Publication Information

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'https://openalex.org/W2115182798', 'https://openalex.org/W2126102214', 'https://openalex.org/W2130516627', 'https://openalex.org/W2131154239', 'https://openalex.org/W2143293886', 'https://openalex.org/W2159672893', 'https://openalex.org/W2169780191', 'https://openalex.org/W2172245690', 'https://openalex.org/W2237759833', 'https://openalex.org/W2404301101', 'https://openalex.org/W2409492879', 'https://openalex.org/W322031617', 'https://openalex.org/W4390186718'], 'related_works': ['https://openalex.org/W4290155861', 'https://openalex.org/W4206347286', 'https://openalex.org/W3200989062', 'https://openalex.org/W3099606857', 'https://openalex.org/W2419529664', 'https://openalex.org/W2156790153', 'https://openalex.org/W2058091174', 'https://openalex.org/W2037492675', 'https://openalex.org/W2016684134', 'https://openalex.org/W1828383458'], 'abstract_inverted_index': {'The': [0, 48, 269, 317, 538, 1411, 1676, 2017, 2128, 2408, 2426, 2452, 2464, 2525, 2655, 2927, 2977, 3102, 3374, 3394, 3625, 4047, 4272], 'serotonin': [1, 270, 593, 613, 729, 749], '5-HT1A': [2, 26, 41, 50, 187, 216, 239, 249, 271, 295, 310, 319, 456, 485, 508, 518, 539, 594, 614, 730, 750, 1038, 1282, 1301, 1323, 1907, 1966, 2032, 2059, 2074, 2278, 2313, 2465, 2476, 2551, 3425, 3801, 3812, 3959, 3980, 4064, 4081, 4096, 4163, 4300, 4324], 'receptor': [3, 27, 42, 51, 188, 202, 217, 240, 250, 265, 272, 296, 311, 320, 457, 471, 486, 509, 519, 534, 812, 822, 1035, 1039, 1302, 1324, 1341, 1430, 1610, 1692, 1709, 1789, 1861, 1908, 1997, 2033, 2047, 2060, 2075, 2118, 2126, 2157, 2211, 2314, 2466, 2477, 2552, 3426, 3813, 3903, 3960, 3967, 3981, 3992, 4301, 4325], 'couples': [4, 273, 1040], 'to': [5, 180, 274, 449, 1041, 1288, 1303, 1361, 1420, 1580, 1603, 1605, 1625, 1651, 1682, 1714, 1721, 1910, 1988, 2134, 2145, 2591, 2637, 2650, 2690, 2768, 2866, 2913, 3116, 3141, 3190, 3198, 3217, 3239, 3333, 3405, 3412, 3468, 3535, 3601, 3719, 3744, 3943, 3988, 4027, 4055, 4171, 4256], 'heterotrimeric': [6, 275, 1304], 'G': [7, 200, 276, 469, 573, 709, 1033, 1305, 1347, 1491, 1716, 1809, 1872], 'proteins': [8, 24, 277, 293, 1306, 1321, 1459, 1492, 3448], 'and': [9, 62, 80, 109, 125, 141, 169, 212, 242, 253, 267, 278, 331, 349, 378, 394, 410, 438, 481, 511, 522, 536, 838, 970, 1219, 1307, 1373, 1422, 1494, 1518, 1523, 1581, 1595, 1650, 1720, 1885, 1979, 2014, 2086, 2105, 2147, 2165, 2188, 2300, 2339, 2368, 2393, 2415, 2442, 2448, 2461, 2480, 2486, 2492, 2545, 2570, 2619, 2639, 2643, 2706, 2732, 2744, 2758, 2794, 2821, 2839, 2869, 2882, 2918, 2952, 3013, 3054, 3123, 3153, 3382, 3423, 3454, 3486, 3527, 3547, 3608, 3620, 3669, 3732, 3902, 4122, 4182, 4290, 4316], 'intracellular': [10, 69, 279, 338, 588, 608, 724, 744, 1308, 1365, 1564, 1801, 1863, 1975, 2093, 2316, 3972, 4174], 'second': [11, 280, 1046, 1309], 'messengers,': [12, 281, 1047, 1310], 'yet': [13, 282], 'no': [14, 283, 1311], 'studies': [15, 284, 1293, 1312], 'have': [16, 30, 285, 299, 1294, 1313, 3803, 4258], 'investigated': [17, 286, 1314], 'the': [18, 33, 40, 60, 67, 72, 77, 138, 145, 155, 186, 193, 215, 236, 248, 287, 302, 309, 329, 336, 341, 346, 407, 414, 424, 455, 462, 484, 505, 517, 582, 586, 591, 602, 606, 611, 718, 722, 727, 738, 742, 747, 815, 820, 1037, 1297, 1300, 1315, 1368, 1424, 1488, 1519, 1606, 1687, 1703, 1708, 1787, 1799, 1859, 1870, 1982, 2003, 2006, 2031, 2046, 2058, 2067, 2072, 2084, 2091, 2096, 2117, 2137, 2285, 2290, 2312, 2328, 2459, 2474, 2532, 2550, 2651, 2771, 2870, 2892, 2962, 2985, 3019, 3078, 3090, 3106, 3126, 3175, 3178, 3184, 3240, 3406, 3424, 3578, 3587, 3631, 3641, 3725, 3774, 3779, 3799, 3966, 3979, 4028, 4050, 4063, 4080, 4090, 4095, 4158, 4162, 4172, 4177, 4180, 4198, 4266, 4293, 4299, 4323], 'possible': [19, 231, 288, 500, 1316], 'role': [20, 232, 289, 501, 1317, 1570, 1903, 1991, 2024, 2124, 3957], 'of': [21, 66, 71, 105, 119, 134, 159, 164, 198, 214, 238, 290, 335, 340, 374, 388, 403, 428, 433, 467, 483, 507, 585, 590, 605, 610, 664, 721, 726, 741, 746, 800, 819, 1045, 1269, 1299, 1318, 1335, 1414, 1427, 1586, 1702, 1707, 1858, 1869, 1974, 1981, 2005, 2066, 2090, 2095, 2116, 2130, 2156, 2277, 2289, 2311, 2377, 2658, 2727, 2773, 2781, 2817, 2824, 2856, 2964, 3050, 3128, 3136, 3161, 3169, 3177, 3188, 3242, 3271, 3300, 3304, 3317, 3327, 3346, 3376, 3401, 3447, 3474, 3483, 3580, 3589, 3605, 3633, 3655, 3665, 3705, 3727, 3730, 3778, 3781, 3796, 3818, 3870, 3970, 4031, 4049, 4084, 4094, 4161, 4176, 4200, 4322], 'additional': [22, 291, 1319], 'receptor-interacting': [23, 292, 1320], 'in': [25, 43, 59, 91, 95, 154, 189, 195, 227, 235, 264, 294, 312, 328, 360, 364, 423, 458, 464, 496, 504, 533, 835, 1322, 1571, 1699, 1798, 1866, 1888, 1906, 1992, 2030, 2061, 2083, 2125, 2379, 2555, 2577, 2609, 2624, 2673, 2702, 2708, 2830, 2891, 2936, 2961, 2984, 3058, 3066, 3125, 3144, 3357, 3431, 3529, 3577, 3674, 3701, 3784, 3810, 3941, 3947, 3958, 4012, 4059, 4072, 4089, 4157, 4298, 4349], 'signaling.': [28, 297, 1325], 'We': [29, 112, 174, 298, 381, 443, 3938], 'found': [31, 300], 'that': [32, 182, 209, 247, 259, 301, 451, 478, 516, 528, 1281, 1329, 1358, 1566, 1679, 1710, 1786, 1805, 1850, 1879, 2019, 2037, 2054, 2071, 2113, 3443, 3806, 3975, 3985, 4071, 4102, 4330], 'ubiquitous': [34, 303, 1563], 'Ca2+-sensor': [35, 304, 1565], 'calmodulin': [36, 305, 2427, 3714], '(CaM)': [37, 306, 1560], 'co-immunoprecipitates': [38, 307, 2056], 'with': [39, 97, 161, 185, 204, 308, 366, 430, 454, 473, 1277, 1346, 1363, 1684, 1791, 1853, 2045, 2057, 2559, 2628, 2677, 2712, 2748, 2753, 2900, 2921, 2931, 2956, 2993, 3005, 3046, 3096, 3234, 3275, 3295, 3342, 3355, 3364, 3543, 3613, 3662, 3750, 3759, 3798, 3965, 4045, 4062, 4079, 4205, 4283, 4335], 'Chinese': [44, 313, 560, 696], 'hamster': [45, 314, 561, 697], 'ovary': [46, 315], 'fibroblasts.': [47, 316, 2063], 'human': [49, 318, 592, 612, 728, 748, 2073], 'contains': [52, 251, 321, 520, 1695, 2076], 'two': [53, 322, 2077, 2138, 4152], 'putative': [54, 323, 2139, 4104, 4153, 4166], 'CaM': [55, 88, 108, 183, 210, 234, 256, 324, 357, 377, 452, 479, 503, 525, 1577, 1599, 1685, 1792, 1806, 1851, 1880, 1905, 1977, 1986, 2020, 2039, 2055, 2079, 2140, 2818, 2960, 3137, 3189, 3272, 3322, 3422, 3797, 3807, 3951, 4032, 4051, 4075, 4086, 4154, 4192, 4252, 4274, 4295, 4326, 4339], 'binding': [56, 93, 211, 257, 325, 362, 480, 526, 1807, 2080, 2141, 3012, 3197, 3221, 4155, 4193, 4253, 4275, 4296, 4327, 4340], 'motifs,': [57, 326, 2081], 'located': [58, 327, 2082], 'N-': [61, 330, 2085, 4181], 'C-terminal': [63, 81, 332, 350, 583, 719, 1355, 1795, 2087, 2301, 4183, 4294], 'juxtamembrane': [64, 333, 1796, 1856, 2088, 4184], 'regions': [65, 258, 334, 527, 2089, 2115, 2310, 4156, 4185, 4194, 4254, 4328], 'third': [68, 337, 587, 607, 723, 743, 1800, 1862, 2092, 2315, 4173], 'loop': [70, 219, 339, 488, 589, 609, 725, 745, 2094, 2317, 4175], 'receptor.': [73, 342, 675, 811, 2097, 4082, 4164], 'Peptides': [74, 343], 'encompassing': [75, 344], 'both': [76, 110, 345, 379], 'N-terminal': [78, 347, 603, 739, 1855, 2291, 4273], '(i3N)': [79, 348], '(i3C)': [82, 351], 'CaM-binding': [83, 352, 1697, 4105, 4167], 'domains': [84, 353, 4168], 'were': [85, 354, 2170, 2180, 2191, 2202, 2213, 2318, 2353, 2417, 2538, 2553, 2589, 2607, 2634, 2671, 2700, 2723, 2738, 2763, 2828, 2872, 2911, 2929, 2954, 2980, 3016, 3044, 3074, 3094, 3121, 3204, 3215, 3329, 3353, 3385, 3403, 3522, 3541, 3560, 3575, 3611, 3722, 3741, 3986, 4169], 'tested': [86, 355], 'for': [87, 137, 144, 233, 356, 406, 413, 502, 1904, 2002, 2108, 2621, 2661, 2687, 2692, 2734, 2765, 2770, 2851, 2946, 2997, 3180, 3196, 3279, 3368, 3387, 3398, 3532, 3537, 3582, 3593, 3737], 'binding.': [89, 358], 'Using': [90, 359, 4352], 'vitro': [92, 361], 'assays': [94, 363], 'combination': [96, 118, 365, 387], 'gel': [98, 367, 2788], 'shift': [99, 368, 2779], 'analysis,': [100, 369], 'we': [101, 207, 370, 476, 2052, 3434, 3977, 4150], 'demonstrated': [102, 371], 'Ca2+-dependent': [103, 372], 'formation': [104, 373], 'complexes': [106, 375, 2783], 'between': [107, 376, 3452, 4268], 'peptides.': [111, 380], 'determined': [113, 382], 'kinetic': [114, 383, 3014], 'data': [115, 245, 384, 514, 3214], 'using': [116, 385, 2333, 2343, 2363, 2440, 2484, 2645, 2786, 3033, 3081, 3183, 3226, 3291, 3336, 3449, 3562, 3766], 'a': [117, 199, 230, 386, 468, 499, 828, 1031, 1042, 1333, 1562, 1583, 1696, 1700, 1723, 1794, 1814, 1867, 1902, 1990, 1999, 2022, 2027, 2321, 2356, 2364, 2374, 2578, 2662, 2703, 2857, 3006, 3025, 3047, 3134, 3158, 3218, 3292, 3296, 3337, 3441, 3481, 3550, 3563, 3602, 3702, 3756, 3954, 4015, 4019, 4098, 4189, 4280, 4305], 'BIAcore': [120, 389, 2205, 3026, 3110], 'surface': [121, 390, 652, 788, 1425, 3034, 3176], 'plasmon': [122, 391, 653, 789, 3035], 'resonance': [123, 177, 392, 446, 554, 690, 3036, 3437], '(SPR)': [124, 393, 3037], 'dansyl-CaM': [126, 395, 3328, 3356, 3377, 3392, 3402], 'fluorescence.': [127, 396], 'SPR': [128, 397, 3103], 'analysis': [129, 398, 2780, 3788, 4321], 'gave': [130, 399, 3314], 'an': [131, 400, 1568, 1854, 2121, 3082, 3315, 3343, 3469], 'apparent': [132, 162, 401, 431, 3395], 'KD': [133, 402, 3396], '∼110': [135, 404], 'nm': [136, 143, 168, 405, 412, 437, 3065, 3140, 3308, 3335, 3619, 3638, 3646], 'i3N': [139, 408, 3666], 'peptide': [140, 409, 579, 599, 715, 735, 2325, 2825], '∼700': [142, 411], 'i3C': [146, 415, 3670], 'peptide.': [147, 416], 'Both': [148, 417, 2098, 4165], 'peptides': [149, 220, 418, 489, 2352, 3061, 3108, 3350, 3673], 'also': [150, 419, 1712], 'caused': [151, 420], 'characteristic': [152, 421], 'shifts': [153, 422], 'fluorescence': [156, 425, 3388], 'emission': [157, 426, 3325], 'spectrum': [158, 427], 'dansyl-CaM,': [160, 429], 'affinities': [163, 432], '87': [165, 434], '±': [166, 171, 435, 440, 3617, 3622, 3776], '23': [167, 436], '1.70': [170, 439], '0.16': [172, 441], 'μm.': [173, 442], 'used': [175, 444, 542, 678, 3435], 'bioluminescence': [176, 445, 553, 689, 3436], 'energy': [178, 447, 555, 691, 3438, 3450, 3467], 'transfer': [179, 448, 3439, 3451, 3466, 3488], 'show': [181, 450], 'interacts': [184, 453, 1790, 1852], 'living': [190, 459], 'cells,': [191, 460, 3433], 'representing': [192, 461], 'first': [194, 463, 1677], 'vivo': [196, 465], 'evidence': [197, 466, 1327], 'protein-coupled': [201, 470, 574, 710, 1034], 'interacting': [203, 472, 2044, 3963], 'CaM.': [205, 474], 'Finally,': [206, 475], 'showed': [208, 477, 1785, 1849], 'phosphorylation': [213, 241, 482, 510, 1725, 2103], 'i3': [218, 487, 2280], 'by': [221, 490, 1275, 1972, 1995, 2043, 2327, 2420, 2540, 2792, 2898, 2916, 2991, 3089, 3206, 3409, 3586, 3724, 3755, 3791, 3962, 4197, 4309], 'protein': [222, 491, 570, 618, 622, 642, 706, 754, 758, 778, 1178, 1348, 1376, 1416, 1717, 1810, 1873, 1913, 1984, 2008, 2110, 2397, 2411, 2693, 3538, 4159], 'kinase': [223, 492, 623, 643, 759, 779, 1914, 3675], 'C': [224, 493, 1085, 1705], 'are': [225, 494, 1273, 2106, 4195, 4347], 'antagonistic': [226, 495], 'vitro,': [228, 497], 'suggesting': [229, 498], 'regulation': [237, 506], 'desensitization.': [243, 512], 'These': [244, 513, 1876, 4068], 'suggest': [246, 515, 4070], 'high': [252, 521], 'moderate': [254, 523], 'affinity': [255, 524], 'may': [260, 529, 1882], 'play': [261, 530, 1883, 1989, 2120, 3953], 'important': [262, 531, 1569, 1884, 2107, 2122], 'roles': [263, 532, 1887, 1893, 3809, 3946], 'signaling': [266, 535, 1575, 1909, 2034, 3814, 3949, 3961], 'function.': [268, 537, 2127, 2158], '1The': [540, 676], 'abbreviations': [541, 677], 'are:': [543, 679], '5-HT,': [544, 680], '5-hydroxytryptamine;': [545, 681], '8-OH-DPAT,': [546, 682], '(±)-8-hydroxy-2-(di-n-propylamino)tetralin;': [547, 683], 'BAPTA-AM,': [548, 684], '1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic': [549, 685], 'acid': [550, 578, 598, 686, 714, 734, 2287, 2385], 'tetra(acetoxymethyl)ester;': [551, 687], 'BRET,': [552, 688], 'transfer;': [556, 692], 'CaM,': [557, 693, 2146, 2989], 'calmodulin;': [558, 694], 'CHO,': [559, 695], 'ovary;': [562, 698], 'EGF,': [563, 699], 'epidermal': [564, 700, 1607], 'growth': [565, 701, 1608], 'factor;': [566, 702], 'ERK,': [567, 703], 'extracellular': [568, 704, 1911], 'signal-regulated': [569, 705, 1912], 'kinase;': [571, 619, 624, 629, 707, 755, 760, 765], 'GPCR,': [572, 708], 'receptor;': [575, 595, 615, 711, 731, 751], 'i3C,': [576, 712], '23-amino': [577, 597, 713, 733], 'fragment': [580, 600, 716, 736, 2453, 2526], 'from': [581, 601, 717, 737, 2172, 2181, 2193, 2204, 2270, 2284, 2403, 2436, 2471, 3105, 3114, 3288, 3331, 3982, 4342], 'end': [584, 604, 720, 740], 'i3N,': [596, 732], 'MAPK,': [616, 752], 'mitogen-activated': [617, 621, 753, 757, 1177, 2007], 'MEK,': [620, 756, 2011], 'MLCK,': [625, 761], 'myosin': [626, 762], 'light': [627, 763, 3634, 3642], 'chain': [628, 764], 'MOPS,': [630, 766, 3679], '3-[N-morpholino]propanesulfonic': [631, 767], 'acid;': [632, 768], 'PBS,': [633, 769], 'phosphate-buffered': [634, 770], 'saline;': [635, 771], 'PDZ,': [636, 772], 'post': [637, 773], 'synaptic': [638, 774], 'density/disks': [639, 775], 'large/ZO-1;': [640, 776], 'PKC,': [641, 777], 'C;': [644, 780], 'PVDF,': [645, 781], 'polyvinylidene': [646, 782], 'fluoride;': [647, 783], 'RLuc,': [648, 784], 'Renilla': [649, 785, 2409], 'luciferase;': [650, 786], 'SPR,': [651, 787], 'resonance;': [654, 790], 'W-7,': [655, 791], 'N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide;': [656, 792], 'YFP,': [657, 793], 'yellow': [658, 794, 2395], 'fluorescent': [659, 795, 2396, 3455, 3477], 'protein;': [660, 796], 'MUSC,': [661, 797], 'Medical': [662, 798], 'University': [663, 799], 'South': [665, 801], 'Carolina;': [666, 802], 'aa,': [667, 803], 'amino': [668, 804, 2286], 'acid(s);': [669, 805], 'mGluR5,': [670, 806], 'metabotropic': [671, 807, 1688], 'glutamate': [672, 808, 1689], 'subtype': [673, 809, 1690], '5': [674, 810, 1691, 3162, 3594, 3606, 3728], 'is': [813, 1561, 1711, 1970, 3489, 4076], 'arguably': [814], 'most': [816], 'well': [817, 2664, 4337], 'characterized': [818, 4196, 4308], '5-HT': [821], 'subtypes,': [823], 'having': [824], 'been': [825, 833, 1418, 1601, 4259], 'cloned': [826], 'over': [827, 3133, 3174, 3208, 3640], 'decade': [829], 'ago.': [830], 'It': [831], 'has': [832, 1417, 1600, 1899], 'implicated': [834], 'numerous': [836, 3811], 'physiological': [837, 3994], 'pathological': [839], 'processes,': [840], 'including': [841, 1048, 1367, 1589, 3816], 'thermoregulation': [842], '(1Balcells-Olivero': [843], 'M.': [844, 885, 981, 1008, 1053, 1068, 1536, 1739, 1830, 3255, 4133, 4137, 4362], 'Cousins': [845], 'M.S.': [846, 1499], 'Seiden': [847], 'L.S.': [848, 1393], 'J.': [849, 906, 1056, 1072, 1074, 1089, 1093, 1120, 1138, 1210, 1229, 1251, 1440, 1472, 1543, 1616, 1660, 1744, 1769, 1833, 1924, 1950, 2234, 2421, 2509, 3253, 3256, 3827, 3853, 3886, 3922, 3998, 4129, 4138, 4358], 'Pharmacol.': [850, 907, 1057, 1075, 1094, 1171, 1509], 'Exp.': [851, 1058], 'Ther.': [852, 1059], '1998;': [853, 890, 908, 966, 989, 1022, 1211, 1230, 1403, 1475, 1925, 3828], '286:': [854], '742-752PubMed': [855], 'Google': [856, 878, 896, 914, 936, 953, 995, 1028, 1063, 1082, 1101, 1130, 1145, 1158, 1175, 1201, 1217, 1236, 1265, 1409, 1454, 1486, 1516, 1557, 1623, 1648, 1674, 1758, 1783, 1847, 1931, 1964, 2244, 2265, 2523, 2808, 3266, 3518, 3834, 3867, 3900, 3936, 4008, 4148, 4232, 4250], 'Scholar,': [857, 954, 996, 1064, 1146, 1159, 1202, 1237, 1932, 2245, 3835, 4233], '2Seletti': [858], 'B.': [859, 1091, 1167, 1187, 3247], 'Benkelfat': [860], 'C.': [861, 870, 945, 1538, 1542, 1741, 1832, 3504], 'Blier': [862, 1005], 'P.': [863, 940, 1006, 4215], 'Annable': [864], 'L.': [865, 887, 1433, 1530], 'Gilbert': [866], 'F.': [867, 1526], 'De': [868, 943], 'Montigny': [869, 944], 'Neuropsychopharmacology.': [871, 946, 965], '1995;': [872, 930, 4223], '13:': [873], '93-104Crossref': [874], 'PubMed': [875, 893, 911, 933, 950, 992, 1025, 1079, 1098, 1129, 1155, 1198, 1214, 1233, 1262, 1406, 1451, 1483, 1513, 1554, 1620, 1645, 1671, 1755, 1780, 1844, 1928, 1961, 2243, 2262, 2520, 2805, 3265, 3515, 3831, 3864, 3897, 3933, 4007, 4145, 4229, 4247], 'Scopus': [876, 894, 912, 934, 951, 993, 1026, 1080, 1099, 1143, 1156, 1199, 1215, 1234, 1263, 1407, 1452, 1484, 1514, 1555, 1621, 1646, 1672, 1756, 1781, 1845, 1929, 1962, 2263, 2521, 2806, 3516, 3832, 3865, 3898, 3934, 4146, 4230, 4248], '(83)': [877], 'Scholar),': [879, 897, 915, 937, 969, 1083, 1102, 1131, 1176, 1218, 1487, 1517, 1624, 1649, 3868, 3901, 4149], 'sexual': [880], 'behavior': [881], '(3Maswood': [882], 'N.': [883, 1532, 1534, 1540], 'Caldarola-Pastuszka': [884], 'Uphouse': [886], 'Brain': [888], 'Res.': [889], '802:': [891], '98-103Crossref': [892], '(36)': [895], 'memory': [898], '(4Edagawa': [899], 'Y.': [900, 1087, 1634, 1941, 3499, 3844, 3913], 'Saito': [901], 'H.': [902, 1465, 1612, 1743, 1828], 'Abe': [903], 'K.': [904, 919, 1632, 4131, 4360], 'Eur.': [905, 1073, 1092], '349:': [909], '221-224Crossref': [910], '(50)': [913], 'immune': [916], 'function': [917], '(5Iken': [918], 'Cheng': [920], 'S.': [921, 987, 998, 1020, 1055, 1066, 1169, 1395, 1399, 1737, 2797, 3249, 3510], 'Fargin': [922, 1106, 2220], 'A.': [923, 988, 1021, 1107, 1148, 1389, 1614, 2221, 2247, 3511], 'Goulet': [924], 'A.C.': [925], 'Kouassi': [926], 'E.': [927, 977, 1731, 1822, 4219], 'Cell': [928, 2543], 'Immun.': [929], '163:': [931], '1-9Crossref': [932], '(123)': [935], 'depression': [938], '(6Blier': [939], 'Bergeron': [941], 'R.': [942, 1000, 1014, 1135, 1507], '1997;': [947, 1254, 1546, 2512, 3889], '16:': [948], '333-338Crossref': [949], '(175)': [952], '7Shiah': [955], 'I.S.': [956], 'Yatham': [957], 'L.N.': [958], 'Lam': [959], 'R.W.': [960], 'Tam': [961], 'E.M.': [962, 1505], 'Zis': [963], 'A.P.': [964], '38:': [967], '6-12Google': [968], 'anxiety': [971], '(8Parks': [972], 'C.L.': [973], 'Robinson': [974], 'P.S.': [975], 'Sibille': [976], 'Shenk': [978], 'T.': [979, 1185, 1244, 2502, 3251, 3879, 4135, 4217, 4364], 'Toth': [980], 'Proc.': [982, 1015, 3505], 'Natl.': [983, 1016, 3506], 'Acad.': [984, 1017, 3507], 'Sci.': [985, 1018, 3508, 4222, 4240], 'U.': [986, 1019, 3509], '95:': [990, 1023], '10734-10739Crossref': [991], '(598)': [994], '9Ramboz': [997], 'Oosting': [999], 'Amara': [1001], 'D.A.': [1002], 'Kung': [1003], 'H.F.': [1004], 'Mendelsohn': [1007], 'Mann': [1009], 'J.J.': [1010], 'Brunner': [1011], 'D.': [1012, 1636, 1655, 1764], 'Hen': [1013], '14476-14481Crossref': [1024], '(707)': [1027], 'Scholar).': [1029, 1266, 1410, 1455, 1558, 1675, 1759, 1965, 2266, 2524, 2809, 3267, 3519, 3937, 4009, 4251], 'As': [1030, 4010, 4188], 'prototypical': [1032], '(GPCR),': [1036], 'broad': [1043], 'array': [1044, 1585], 'adenylyl': [1049], 'cyclase': [1050], '(10De': [1051], 'Vivo': [1052], 'Maayani': [1054], '1986;': [1060, 1076, 1140], '238:': [1061], '248-253PubMed': [1062], '11Weiss': [1065], 'Sebben': [1067], 'Kemp': [1069], 'D.E.': [1070], 'Bockaert': [1071], '120:': [1077], '227-230Crossref': [1078], '(78)': [1081], 'phospholipase': [1084], '(12Claustre': [1086], 'Benavides': [1088], 'Scatton': [1090], '1988;': [1095, 2259], '149:': [1096], '149-153Crossref': [1097], '(45)': [1100], 'PKC': [1103, 1724, 2102, 2169, 3659], '(13Raymond': [1104, 2218], 'J.R.': [1105, 1193, 1208, 1227, 1250, 1922, 1949, 2219, 2249, 2508, 3825, 3852, 3885, 3921, 3997], 'Middleton': [1108, 2222], 'J.P.': [1109, 1528, 2223], 'Graff': [1110, 2224], 'J.M.': [1111, 1161, 1659, 1733, 1768, 2225], 'Haupt': [1112, 2226], 'D.M.': [1113, 2227], 'Caron': [1114, 2228, 2254], 'M.G.': [1115, 2229, 2255], 'Lefkowitz': [1116, 1190, 1400, 1946, 2230, 2256, 3849, 3918], 'R.J.': [1117, 1191, 1401, 1947, 2231, 2257, 3850, 3919], 'Dennis': [1118, 2232], 'V.W.': [1119, 2233], 'Biol.': [1121, 1252, 1441, 1473, 1544, 1661, 1745, 1770, 1834, 1951, 2235, 2510, 3257, 3854, 3887, 3923, 3999], 'Chem.': [1122, 1253, 1442, 1474, 1545, 1662, 1746, 1771, 1835, 1952, 2236, 2511, 3258, 3855, 3888, 3924, 4000], '1989;': [1123, 1172, 2237], '264:': [1124, 2238], '21943-21950Abstract': [1125, 2239], 'Full': [1126, 1257, 1259, 1446, 1448, 1478, 1480, 1549, 1551, 1666, 1668, 1750, 1752, 1775, 1777, 1839, 1841, 1956, 1958, 2240, 2515, 2517, 3262, 3859, 3861, 3892, 3894, 3928, 3930, 4004, 4226, 4244], 'Text': [1127, 1258, 1260, 1447, 1449, 1479, 1481, 1550, 1552, 1667, 1669, 1751, 1753, 1776, 1778, 1840, 1842, 1957, 1959, 2241, 2516, 2518, 3263, 3860, 3862, 3893, 3895, 3929, 3931, 4005, 4227, 4245], 'PDF': [1128, 1261, 1450, 1482, 1553, 1670, 1754, 1779, 1843, 1960, 2242, 2519, 3264, 3863, 3896, 3932, 4006, 4228, 4246], 'K+': [1132], 'channels': [1133], '(14Andrade': [1134], 'Nicoll': [1136], 'R.A.': [1137, 1379], 'Physiol.': [1139], '394:': [1141], '99-124Crossref': [1142], '(459)': [1144], '15Colino': [1147], 'Halliwell': [1149], 'J.V.': [1150], 'Nature.': [1151, 1402, 2258], '1987;': [1152, 2802], '328:': [1153], '73-77Crossref': [1154], '(381)': [1157], '16Zgombick': [1160], 'Beck': [1162], 'S.G.': [1163], 'Mahle': [1164], 'C.D.': [1165], 'Craddock-Royal': [1166], 'Mayaani': [1168], 'Mol.': [1170, 1508], '35:': [1173, 1196], '484-494PubMed': [1174], 'kinases': [1179, 2009], '(MAPKs)': [1180], '(17Garnovskaya': [1181], 'M.N.': [1182, 1204, 1223, 1239, 1918, 1939, 2497, 3821, 3842, 3874, 3911], 'Van': [1183, 1242, 2500, 3877], 'Biesen': [1184, 1243, 2501, 3878], 'Hawes': [1186], 'Ramos': [1188], 'S.C.': [1189], 'Raymond': [1192, 1207, 1226, 1249, 1921, 1948, 2248, 2507, 3824, 3851, 3884, 3920], 'Biochemistry.': [1194], '1996;': [1195], '13716-13722Crossref': [1197], '(97)': [1200], '18Garnovskaya': [1203], 'Mukhin': [1205, 1224, 1919, 1936, 3822, 3839, 3908], 'Y.V.': [1206, 1225, 1920, 1937, 3823, 3840, 3909], 'Biochem.': [1209, 1228, 1615, 1923, 3826, 4221, 4239], '330:': [1212, 1231, 1926, 3829], '489-495Crossref': [1213, 1232, 1927, 3830], '(41)': [1216, 1235, 1622, 1930, 3833], 'Na+/H+': [1220, 1369, 3871], 'exchange': [1221, 3872], '(18Garnovskaya': [1222, 1917, 3820], '19Garnovskaya': [1238], 'Gettys': [1240, 2498, 3875], 'T.W.': [1241, 2499, 3876], 'Chuprun': [1245, 2503, 3880], 'J.K.': [1246, 2504, 3881], 'Prpic': [1247, 2505, 3882], 'V.': [1248, 1735, 2506, 3883], '272:': [1255, 1547, 2513, 3890], '7770-7776Abstract': [1256, 2514, 3891], '(46)': [1264, 2522, 3899], 'Virtually': [1267], 'all': [1268], 'these': [1270, 2114], 'cellular': [1271, 1587], 'effects': [1272, 2042], 'averted': [1274], 'pretreatment': [1276], 'pertussis': [1278], 'toxin,': [1279], 'indicating': [1280, 2112], 'receptors': [1283], 'couple': [1284], 'specifically': [1285], 'and/or': [1286, 1344], 'preferentially': [1287], 'Gi/o': [1289, 2109], 'proteins.': [1290, 1597, 4344], 'Although': [1291], 'previous': [1292], 'thoroughly': [1295], 'detailed': [1296], 'coupling': [1298, 3084], 'Growing': [1326], 'suggests': [1328, 2036], 'GPCRs': [1330, 1353, 1653], 'can': [1331, 1338, 1578, 3465], 'bind': [1332, 1421, 1579, 1604, 1715, 2144], 'variety': [1334], 'proteins,': [1336, 1366, 1588], 'which': [1337, 1694, 2012, 4025], 'subsequently': [1339], 'modify': [1340], 'signaling,': [1342, 1890], 'internalization,': [1343], 'interaction': [1345], 'subunits.': [1349], 'For': [1350, 2602, 2695], 'example,': [1351], 'several': [1352, 1572, 3748, 4201, 4206, 4262], 'contain': [1354, 1722, 2100], 'PDZ': [1356], 'motifs': [1357, 2099, 4263, 4341], 'permit': [1359], 'them': [1360], 'interact': [1362, 1683], 'multiple': [1364], 'exchanger': [1370], 'regulatory': [1371, 2123], 'factor': [1372, 1609], 'post-synaptic': [1374], 'density': [1375, 4048], 'PSD-95': [1377], '(20Hall': [1378], 'Premont': [1380], 'R.T.': [1381], 'Chow': [1382], 'C.W.': [1383], 'Blitzer': [1384], 'J.T.': [1385], 'Pitcher': [1386], 'J.A.': [1387], 'Claing': [1388], 'Stoffel': [1390], 'R.H.': [1391], 'Barak': [1392], 'Shenolikar': [1394], 'Weinman': [1396], 'E.J.': [1397], 'Grinstein': [1398], '392:': [1404], '626-630Crossref': [1405], '(516)': [1408], 'ζ': [1412], 'isoform': [1413], '14-3-3': [1415], 'shown': [1419, 1602, 1681, 3772, 3805, 4011], 'regulate': [1423], 'expression': [1426, 1980, 2398, 2412], 'different': [1428], 'α2-adrenergic': [1429], 'subtypes': [1431], '(21Prezeau': [1432], 'Richman': [1434], 'J.G.': [1435], 'Edwards': [1436], 'S.W.': [1437], 'Limbird': [1438], 'L.E.': [1439], '1999;': [1443, 1663, 1772, 1953, 3512, 3856, 3925], '274:': [1444, 1664, 1773, 1954, 3857, 3926], '13462-13469Abstract': [1445], '(76)': [1453], 'Other': [1456], 'reported': [1457, 1901], 'GPCR-interacting': [1458], 'include': [1460], 'endothelial': [1461], 'nitric-oxide': [1462], 'synthase': [1463], '(22Ju': [1464], 'Venema': [1466, 1470], 'V.J.': [1467], 'Marrero': [1468], 'M.B.': [1469], 'R.C.': [1471], '273:': [1476], '24025-24029Abstract': [1477], '(139)': [1485], 'small': [1489], 'nonheterotrimeric': [1490], 'ARF': [1493], 'RhoA': [1495], '(23Robertson': [1496], 'D.N.': [1497], 'Johnson': [1498, 3503], 'Moggach': [1500], 'L.O.': [1501], 'Holland': [1502], 'P.J.': [1503], 'Lutz': [1504], 'Mitchell': [1506], '2003;': [1510], '64:': [1511], '1239-1250Crossref': [1512], '(54)': [1515], 'tyrosine': [1520], 'phosphatases': [1521], 'SHP-1': [1522], 'SHP-2': [1524], '(24Lopez': [1525], 'Esteve': [1527], 'Buscail': [1529], 'Delesque': [1531], 'Saint-Laurent': [1533], 'Theveniau': [1535], 'Nahmias': [1537], 'Vaysse': [1539], 'Susini': [1541], '24448-24454Abstract': [1548], '(154)': [1556], 'Calmodulin': [1559], 'plays': [1567, 2021, 3808], 'downstream': [1573, 3948], 'GPCR': [1574, 1678, 1889], 'pathways.': [1576], 'modulate': [1582], 'diverse': [1584, 1886], 'enzymes,': [1590], 'ion': [1591], 'channels,': [1592], 'transcription': [1593], 'factors,': [1594], 'cytoskeletal': [1596], 'Recently,': [1598], '(25Li': [1611], 'Villalobo': [1613], '2002;': [1617, 1642], '362:': [1618], '499-505Crossref': [1619], 'platelet': [1626], 'glycoprotein': [1627], 'VI': [1628], '(26Andrews': [1629], 'R.K.': [1630], 'Suzuki-Inoue': [1631], 'Shen': [1633], 'Tulasne': [1635], 'Watson': [1637], 'S.P.': [1638], 'Berndt': [1639], 'M.C.': [1640], 'Blood.': [1641], '99:': [1643], '4219-4221Crossref': [1644], '(75)': [1647], 'some': [1652, 2154, 3572, 3709], '(27Wang': [1654, 1763], 'Sadee': [1656, 1765], 'W.': [1657, 1766], 'Quillan': [1658, 1767], '22081-22088Abstract': [1665, 1774], '(108)': [1673, 1782], 'was': [1680, 1686, 2133, 2268, 2341, 2370, 2401, 2434, 2454, 2469, 2527, 2665, 2746, 2784, 2864, 2896, 3004, 3131, 3172, 3194, 3236, 3273, 3286, 3380, 3598, 3628, 3660, 3717, 3764, 3789, 4038, 4043, 4053, 4277, 4302], '(mGluR5),': [1693], 'site': [1698, 1726], 'region': [1701, 1797, 1857, 2483, 4276, 4297], 'extended': [1704], 'terminus': [1706], 'known': [1713], 'βγ': [1718], 'subunits': [1719], '(28El': [1727], 'Far': [1728], 'O.': [1729, 1824], 'Bofill-Cardona': [1730, 1818], 'Airas': [1732], "O'Connor": [1734], 'Boehm': [1736], 'Freissmuth': [1738, 1829], 'Nanoff': [1740, 1831], 'Betz': [1742], '2001;': [1747], '276:': [1748], '30662-30669Abstract': [1749], '(57)': [1757], 'Wang': [1760], 'et': [1761, 1819, 3244], 'al.': [1762, 1820, 3245], 'Scholar)': [1784, 1848], 'μ-opioid': [1788], 'at': [1793, 2025, 2574, 2612, 2848, 2949, 2974, 3000, 3018, 3071, 3164, 3282, 3306, 3371, 3390, 3492, 3553, 3615, 3636, 3644, 3734, 3993, 4022, 4179, 4287, 4312], 'loop.': [1802], 'They': [1803], 'concluded': [1804], 'reduces': [1808], 'coupling,': [1811, 2111], 'probably': [1812], 'through': [1813, 3968], 'competitive': [1815], 'mechanism.': [1816], 'Similarly,': [1817], '(29Bofill-Cardona': [1821], 'Kudlacek': [1823], 'Yang': [1825], 'Q.': [1826], 'Ahorn': [1827], '2000;': [1836, 4142], '275:': [1837], '32672-32680Abstract': [1838], '(114)': [1846], 'D2-dopamine': [1860], 'loop,': [1864], 'resulting': [1865], 'blockade': [1868], 'receptor-operated': [1871], 'activation': [1874, 1969, 1994, 2004, 3869], 'switch.': [1875], 'examples': [1877, 4346], 'indicate': [1878], 'interactions': [1881], 'although': [1891], 'those': [1892], 'remain': [1894], 'largely': [1895], 'undefined.': [1896], 'Our': [1897], 'group': [1898], 'previously': [1900, 2216, 2730, 3804], '(ERK)': [1915], 'MAPKs': [1916, 3819], '30Della': [1933, 3836], 'Rocca': [1934, 3837, 3906], 'G.J.': [1935, 1943, 3838, 3846, 3907, 3915], 'Garnovskaya': [1938, 3841, 3910], 'Daaka': [1940, 3843, 3912], 'Clark': [1942, 3845, 3914], 'Luttrell': [1944, 3847, 3916], 'L.M.': [1945, 3848, 3917], '4749-4753Abstract': [1955, 3858, 3927], '(132)': [1963, 2807, 3866, 3935], 'receptor-mediated': [1967], 'ERK': [1968, 1993], 'inhibited': [1971], 'chelation': [1973], 'Ca2+,': [1976], 'inhibitors,': [1978], 'CaM-sequestering': [1983], 'calspermin.': [1985], 'appears': [1987], 'modulating': [1996], 'endocytosis,': [1998], 'step': [2000, 2029], 'required': [2001], 'kinase,': [2010], 'phosphorylates': [2013], 'activates': [2015], 'ERK.': [2016], 'fact': [2018], 'vital': [2023], 'such': [2026, 4111], 'proximal': [2028, 3956], 'pathway': [2035], 'perhaps': [2038], 'exerts': [2040], 'its': [2041, 2431, 3944, 3971], 'itself.': [2048], 'In': [2049, 3571, 3648, 3708], 'this': [2050, 2131, 2151, 3487, 3991], 'work,': [2051], 'report': [2053], 'CHO': [2062, 2605, 2698, 3983, 4073], 'A': [2064, 3457], 'search': [2065, 4100], 'primary': [2068], 'sequence': [2069, 2288, 2429, 2468, 2479, 4160], 'revealed': [2070, 4329], 'potential': [2078], 'consensus': [2101], 'sites': [2104, 2142, 2495, 3093, 4106], 'likely': [2119], 'purpose': [2129], 'work': [2132], 'determine': [2135, 3420], 'whether': [2136, 2150, 3421], 'could': [2143, 4332], 'if': [2148], 'so,': [2149], 'would': [2152], 'alter': [2153], 'parameter': [2155], 'Materials—Purified': [2159], 'bovine': [2160, 2598, 2679, 2933, 3712], 'brain': [2161, 2168, 3658, 3713], 'calmodulin,': [2162, 2164], 'biotinylated': [2163, 2959], 'purified': [2166, 2354, 3287, 3656, 3711], 'rat': [2167, 3657], 'purchased': [2171, 2192, 2203, 2269], 'Calbiochem': [2173], '(La': [2174], 'Jolla,': [2175], 'CA).': [2176, 2209, 2407], 'Mouse': [2177], 'anti-CaM': [2178], 'antibodies': [2179, 2212], 'Upstate': [2182], 'Biotechnology': [2183], '(Charlottesville,': [2184], 'VA).': [2185], 'Coelenterazine': [2186, 3596], 'h': [2187, 2584, 2623, 2689, 2948, 2999, 3281, 3370, 3534, 3597], 'dansyl': [2189, 3319], 'chloride': [2190], 'Molecular': [2194], 'Probes': [2195], '(Eugene,': [2196], 'OR).': [2197], 'CM5': [2198], 'carboxymethylated': [2199], 'sensor': [2200, 3040, 3079], 'chips': [2201, 3041, 3080], 'AB': [2206], '(Foster': [2207], 'City,': [2208], 'Anti-5-HT1A': [2210], 'raised': [2214], 'as': [2215, 2729, 2790, 3087, 3524, 3630, 4112, 4279, 4304], 'described': [2217, 2731, 2791, 3088, 3525, 4255], '31Fargin': [2246], 'Lohse': [2250], 'M.J.': [2251], 'Kobilka': [2252], 'B.K.': [2253], '335:': [2260], '358-360Crossref': [2261], '(523)': [2264], '[γ-32P]ATP': [2267, 3731], 'PerkinElmer': [2271], 'Life': [2272, 3569], 'Sciences': [2273], '(Boston,': [2274], 'MA).': [2275], 'Synthesis': [2276, 2331], 'Receptor': [2279], 'Loop': [2281, 4093], 'Peptides—Peptides': [2282], 'derived': [2283], '(i3N,': [2292], 'aa': [2293, 2297, 2303, 2307], '215–237,': [2294, 2298], 'YGRIFRAARFRIRKTVKKVEKTG;': [2295], 'i3N-P,': [2296], 'YGRIFRAARFRIRKpTVKKVEKTG)': [2299], '(i3C,': [2302], '328–350,': [2304, 2308], 'EAKRKMALARERKTVKTLGIIMG;': [2305], 'i3C-P,': [2306], 'EAKRKMALARERKpTVKTLGIIMG)': [2309], 'synthesized': [2319, 3237], 'on': [2320, 2355, 2874, 3024, 3077, 4108, 4265], 'Rainin': [2322], 'PS3': [2323], 'automated': [2324], 'synthesizer': [2326], 'MUSC': [2329, 3020], 'Peptide': [2330, 2337], 'Facility,': [2332, 2389], 'standard': [2334], 'solid-phase': [2335], 'methods.': [2336], 'size': [2338], 'purity': [2340], 'verified': [2342, 2539], 'matrix-assisted': [2344], 'laser': [2345], 'desorption': [2346], 'ionization/time-of-flight': [2347], 'mass': [2348, 3298], 'spectrometry.': [2349], 'When': [2350], 'necessary,': [2351], 'Waters': [2357], 'Delta': [2358], 'Prep': [2359], '3000': [2360, 3027], 'chromatography': [2361], 'system': [2362, 3029], 'C-18': [2365], 'silica': [2366], 'column,': [2367], 'elution': [2369], 'carried': [2371], 'out': [2372], 'across': [2373], 'linear': [2375, 3410], 'gradient': [2376], 'acetonitrile': [2378], 'water': [2380], 'containing': [2381, 2445, 2473, 2489, 2594, 2814, 2878, 2942], '0.1%': [2382, 2943], '(w/v)': [2383], 'trifluoroacetic': [2384], '(Emory': [2386], 'University,': [2387], 'Microchemical': [2388], 'Atlanta,': [2390], 'GA).': [2391], 'Plasmids': [2392], 'Transfections—The': [2394], 'vector': [2399, 2536], 'eYFP-N1': [2400, 2533], 'obtained': [2402], 'Clontech': [2404], '(San': [2405], 'Jose,': [2406], 'Luciferase': [2410], 'vectors': [2413], 'RLuc-N1': [2414, 2460], 'RLuc-C1': [2416, 2462], 'kindly': [2418], 'provided': [2419, 4348], 'Yordy': [2422], '(MUSC,': [2423], 'Charleston,': [2424], 'SC).': [2425], 'coding': [2428, 2467, 2478], 'without': [2430, 2988, 3211], 'stop': [2432], 'codon': [2433], 'amplified': [2435, 2470], 'HeLa': [2437], 'cell': [2438], 'cDNA': [2439], 'sense': [2441, 2485], 'antisense': [2443, 2487], 'primers': [2444, 2488], 'unique': [2446, 2490], 'XmaI': [2447], 'SacII': [2449], 'restriction': [2450, 2494], 'sites.': [2451], 'then': [2455, 2528, 2635, 2739, 2953, 2981, 3075, 3599, 3742], 'subcloned': [2456, 2529], 'in-frame': [2457, 2530], 'into': [2458, 2531, 2741, 3428, 3549, 4261], 'vectors.': [2463], 'pcDNA3.1': [2472], 'entire': [2475], '3′': [2481], 'untranslated': [2482], 'BaMH1': [2491], 'XhoI': [2493], '(19Garnovskaya': [2496, 3873], 'vector.': [2534], 'All': [2535], 'constructs': [2537], 'DNA': [2541, 2660], 'sequencing.': [2542], 'Culture': [2544], 'Transfection—CHO-K1': [2546], '(CHO)': [2547], 'cells': [2548, 2588, 2606, 2616, 2670, 2699, 3120, 3193, 3203, 3521, 3574, 4074], 'expressing': [2549], 'maintained': [2554], "F-12/Ham's": [2556, 2625, 2641, 2674, 2709, 2750, 3530], 'medium,': [2557], 'supplemented': [2558, 2627, 2676, 2711, 2752, 3363], '10%': [2560, 2629, 2683, 2713, 2754], 'fetal': [2561, 2630, 2684, 2714, 2755], 'calf': [2562, 2631, 2685, 2715, 2756], 'serum,': [2563], 'streptomycin': [2564], '(100': [2565, 2568, 3062], 'μg/ml),': [2566], 'penicillin': [2567], 'units/ml),': [2569], 'gentamicin': [2571], '(400': [2572], 'μg/ml)': [2573], '37': [2575], '°C': [2576, 2850, 3736], '5%': [2579, 2932], 'CO2-enriched,': [2580], 'humidified': [2581], 'atmosphere.': [2582], '24–48': [2583], 'before': [2585], 'each': [2586, 2867, 3391, 3399, 3785], 'experiment,': [2587], 'switched': [2590], 'serum-free': [2592, 2640], 'medium': [2593, 2626, 2642, 2675, 2710, 2751], '0.5%': [2595, 2678], 'fatty': [2596], 'acid-free': [2597], 'serum': [2599, 2680, 2686, 2716, 2757, 2934], 'albumin': [2600, 2681, 2935], '(Sigma).': [2601], 'transient': [2603], 'transfections,': [2604, 2697], 'plated': [2608, 2701], '6-well': [2610], 'plates': [2611], '1': [2613, 2845, 2888, 2947, 2970, 2998, 3097, 3142, 3280, 3554, 3590, 3686, 3689, 3738, 4289], '×': [2614, 3555], '105': [2615, 3556], 'per': [2617, 3321], 'well,': [2618], 'cultured': [2620, 2672, 2707, 2733, 2764, 3528], '24': [2622], 'serum.': [2632], 'Cells': [2633, 2722, 2737, 2762, 3540], 'transferred': [2636, 3743], 'antibiotic-': [2638], 'transfected': [2644, 2659, 2724, 3523, 3987], 'LipofectAMINE': [2646], '2000': [2647], 'reagent': [2648], 'according': [2649, 3238], "manufacturer's": [2652], 'instructions': [2653], '(Invitrogen).': [2654], 'final': [2656, 3603, 3757], 'amount': [2657], 'single': [2663], '∼2': [2666], 'μg.': [2667], 'After': [2668], 'transfection,': [2669], 'or': [2682, 2844, 2887, 2969, 4056], '48': [2688, 2735, 3533], 'allow': [2691, 2769, 3536], 'expression.': [2694, 3539], 'stable': [2696, 2774], '12-well': [2704], 'plate': [2705, 3552, 3566], 'until': [2717], 'they': [2718, 4331], 'reached': [2719], '∼90–95%': [2720], 'confluence.': [2721], '(1': [2725], 'μg': [2726, 3270, 3277], 'DNA/well)': [2728], 'h.': [2736, 3739], 'sub-cultured': [2740], '100-mm': [2742], 'dishes,': [2743], 'media': [2745, 3531], 'replaced': [2747], 'fresh': [2749], '400': [2759, 3115, 3154, 3332], 'μg/ml': [2760, 2958], 'Geneticin.': [2761], '1–2': [2766], 'weeks': [2767], 'selection': [2772], 'clones.': [2775], 'Gel': [2776], 'Shift': [2777], 'Assays—Gel': [2778], 'CaM-peptide': [2782], 'performed': [2785, 3017, 3790, 4044], 'urea-polyacrylamide': [2787], 'electrophoresis,': [2789], 'Erickson-Viitanen': [2793], 'Delgrado': [2795], '(33Erickson-Viitanen': [2796], 'DeGrado': [2798, 4236], 'W.F.': [2799, 4237], 'Methods': [2800], 'Enzymol.': [2801], '139:': [2803], '455-478Crossref': [2804], 'Reactions': [2810, 3740], '(30-μl': [2811], 'total': [2812, 3703], 'volume)': [2813], '300': [2815], 'pmol': [2816], '(∼5': [2819], 'μg)': [2820], 'increasing': [2822, 3663], 'amounts': [2823], '(0–3000': [2826], 'pmol)': [2827], 'incubated': [2829, 2955, 3274, 3354, 3576, 3661, 3733], '100': [2831, 2922, 2937, 3148, 3358, 3496, 3698], 'mm': [2832, 2842, 2846, 2885, 2889, 2923, 2938, 2967, 2971, 3068, 3146, 3149, 3359, 3366, 3545, 3678, 3683, 3687, 3690], 'Tris-HCl,': [2833, 2924, 2939, 3360], 'pH': [2834, 2925, 2940, 3072, 3361, 3680], '7.5,': [2835, 2941, 3362], '4': [2836, 2879, 2975, 3283], 'm': [2837, 2880, 3052, 3056, 3098], 'urea,': [2838], 'either': [2840, 2883, 2965], '0.1': [2841, 2884, 2966, 3365, 3692], 'CaCl2': [2843, 2886, 2968, 3156, 3367], 'EGTA': [2847, 2890, 2972], '22': [2849], '30': [2852, 3706, 3735], 'min.': [2853, 3595], '15': [2854], 'μl': [2855, 3168], '50%': [2858], 'glycerol/0.1%': [2859], 'bromphenol': [2860], 'blue': [2861, 2902], 'loading': [2862], 'buffer': [2863, 2987, 3210, 3676], 'added': [2865, 3600, 3718], 'reaction,': [2868], 'samples': [2871, 4060], 'resolved': [2873], '14%': [2875], 'polyacrylamide': [2876], 'gels': [2877], 'urea': [2881], 'running': [2893, 3209], 'buffer.': [2894], 'Protein': [2895], 'visualized': [2897], 'staining': [2899, 2904], 'Gel-code': [2901], '(Pierce)': [2903], 'reagent.': [2905, 3008], 'Blot': [2906], 'Overlay': [2907], 'Assays—Peptides': [2908], '(1–100': [2909], 'nmol)': [2910], 'immobilized': [2912, 3076, 3107], 'PVDF': [2914, 2978], 'membranes': [2915, 2928, 2979], 'slot-blot': [2917], 'washed': [2919, 2982, 3747], 'twice': [2920], '7.5.': [2926], 'blocked': [2930, 3095, 3124], 'Tween': [2944], '20': [2945, 3583], 'room': [2950, 3001, 3372], 'temperature,': [2951], '0.5': [2957], 'presence': [2963, 3579, 4199], 'overnight': [2973], '°C.': [2976, 3166, 3284], '3×': [2983], 'same': [2986], 'followed': [2990, 3585, 3754], 'incubation': [2992], 'alkaline': [2994], 'phosphatase-conjugated': [2995], 'avidin': [2996], 'temperature.': [3002, 3373], 'Detection': [3003], 'chemiluminescent': [3007], 'Surface': [3009], 'Plasmon': [3010], 'Resonance—Real-time': [3011], 'analyses': [3015], 'Biomolecular': [3021], 'Resource': [3022], 'Facility': [3023], 'biosensor': [3028], '(Pharmacia': [3030], 'Biosensor': [3031], 'AB)': [3032], 'measurements.': [3038], 'Carboxymethylated': [3039], '(type': [3042], 'CM5)': [3043], 'activated': [3045, 3122], '1:1': [3048, 3219], 'mixture': [3049], '0.2': [3051], 'N-ethyl-N′-(3-dimethylaminopropyl)carbodiimide': [3053], '0.05': [3055], 'N-hydroxysuccinimide': [3057], 'water.': [3059], 'Synthetic': [3060], 'μg/ml,': [3063], '31.5': [3064], '10': [3067, 3167, 3269], 'sodium': [3069], 'acetate': [3070], '4.8)': [3073], 'amine': [3083], 'kit': [3085], '(BIAcore)': [3086], 'supplier.': [3091], 'Unreacted': [3092], 'ethanolamine': [3099], '(pH': [3100, 3151], '8.5).': [3101], 'signals': [3104], 'generated': [3109, 3386], 'response': [3111], 'units': [3112, 3320], 'ranging': [3113], '720.': [3117], 'Control': [3118], 'flow': [3119, 3160, 3192, 3200], 'absence': [3127], 'protein.': [3129], 'Binding': [3130, 3187, 3213, 4087], 'evaluated': [3132], 'range': [3135], 'concentrations': [3138, 3664], '(15.6': [3139], 'μm)': [3143, 3352, 3379, 3668, 3672, 3716], '150': [3145], 'NaCl,': [3147], 'HEPES': [3150], '7.4),': [3152], 'μm': [3155, 3591, 3699], 'under': [3157, 3223, 4033], 'continuous': [3159], 'μl/min': [3163], '25': [3165, 3618, 3623, 3682], 'CaM-containing': [3170], 'solutions': [3171], 'pulsed': [3173], 'chip': [3179], '2': [3181, 3369], 'min': [3182], 'kinject': [3185], 'command.': [3186], 'peptide-immobilized': [3191], 'corrected': [3195], 'control': [3199], 'cells.': [3201], 'Flow': [3202], 'regenerated': [3205], 'passing': [3207], 'CaCl2.': [3212], 'fitted': [3216], 'Langmuir': [3220], 'model': [3222], 'steady-state': [3224], 'conditions': [3225], 'BIAevaluation': [3227], 'version': [3228], '3.1': [3229], 'software': [3230], '(BIAcore).': [3231], 'Fluorometric': [3232], 'Measurements': [3233], 'Dansyl-CaM—Dansyl-CaM': [3235], 'method': [3241], 'Bertrand': [3243], '(34Bertrand': [3246], 'Wakabayashi': [3248], 'Ikeda': [3250], 'Pouyssegur': [3252], 'Shigekawa': [3254], '1994;': [3259], '269:': [3260], '13703-13709Abstract': [3261], 'Briefly,': [3268], '∼1': [3276], 'dansyl-chloride': [3278], 'Dansyl-CaM': [3285], 'unincorporated': [3289], 'dye': [3290], 'Centricon™': [3293], 'concentrator': [3294], 'molecular': [3297], 'cutoff': [3299], '10,000': [3301], 'Da.': [3302], 'Measurement': [3303], 'absorbance': [3305], '340': [3307, 3347], '(molar': [3309], 'extinction': [3310], 'coefficient:': [3311], '3,400': [3312], 'm–1cm–1)': [3313], 'incorporation': [3316], '∼1.3': [3318], 'molecule.': [3323], 'Fluorescence': [3324, 3558], 'spectra': [3326], 'measured': [3330, 3765], '600': [3334], 'SLM': [3338], '8000™C': [3339], 'spectrofluorometer': [3340], '(Aminco-Bowman)': [3341], 'excitation': [3344], 'wavelength': [3345], 'nm.': [3348, 3624], 'Test': [3349], '(0–8': [3351], 'concentration': [3375, 3400, 3604], '(0.1–0.5': [3378], 'varied,': [3381], 'concentration-response': [3383], 'curves': [3384], 'enhancement': [3389], 'concentration.': [3393], 'values': [3397], 'fit': [3404], 'Hill': [3407], 'equation': [3408], 'regression': [3411], 'calculate': [3413], 'true': [3414], 'affinities.': [3415], 'Bioluminescence': [3416], 'Resonance': [3417], 'Energy': [3418], 'Transfer—To': [3419], 'come': [3427], 'close': [3429, 3445], 'proximity': [3430, 3446], 'intact': [3432], '(BRET),': [3440], 'technique': [3442], 'detects': [3444], 'luminescent': [3453], 'tags.': [3456], 'bioluminescent': [3458], 'donor': [3459], 'source': [3460], '(Renilla': [3461], 'reniformis': [3462], 'luciferase,': [3463], 'RLuc)': [3464], 'acceptor': [3470], 'fluorophore': [3471], '(yellow': [3472], 'variant': [3473], 'Aequorea': [3475], 'green': [3476], 'protein,': [3478], 'YFP)': [3479], 'within': [3480], 'radius': [3482], '∼50': [3484], 'Å,': [3485], 'virtually': [3490], 'undetectable': [3491], 'distances': [3493], 'greater': [3494], 'than': [3495], 'Å': [3497], '(35Xu': [3498], 'Piston': [3500], 'D.W.': [3501], 'Hirschie': [3502], '96:': [3513], '151-156Crossref': [3514], '(495)': [3517], 'CHO-5-HT1AR': [3520], 'above': [3526], 'detached': [3542], 'PBS/1': [3544], 'EDTA': [3546], 'distributed': [3548], '96-well': [3551], 'cells/well.': [3557], 'measurements': [3559, 3610], 'acquired': [3561], 'Victor2': [3564], 'multilabel': [3565], 'reader': [3567], '(PerkinElmer': [3568], 'Sciences).': [3570], 'cases,': [3573, 3710], 'inhibitors': [3581], 'min,': [3584], 'addition': [3588, 3726, 3942], '8-OH-DPAT': [3592], 'μm,': [3607], 'sequential': [3609], 'made': [3612], 'filters': [3614], '460': [3616, 3645], '525': [3621, 3637], 'BRET': [3626], 'ratio': [3627, 3632], 'calculated': [3629], 'emitted': [3635, 3643], '(YFP)': [3639], '(Luciferase).': [3647], 'Vitro': [3649], 'Kinase': [3650], 'Assays—Thirty-five': [3651], 'nanograms': [3652], '(∼0.06': [3653], 'unit)': [3654], '(0–5': [3667], '(0–10': [3671], '(20': [3677], '7.2,': [3681], 'β-glycerol': [3684], 'phosphate,': [3685], 'dithiothreitol,': [3688], 'CaCl2,': [3691], 'mg/ml': [3693, 3696], 'phosphatidylserine,': [3694], '0.01': [3695], 'diacylglycerol,': [3697], '[γ-32P]ATP)': [3700], 'volume': [3704], 'μl.': [3707], '(0–120': [3715], 'reactions.': [3720], 'Assays': [3721], 'started': [3723], 'μCi': [3729], 'nitrocellulose': [3745], 'squares,': [3746], 'times': [3749], '0.75%': [3751], 'phosphoric': [3752], 'acid,': [3753], 'wash': [3758], '100%': [3760], 'acetone.': [3761], 'Bound': [3762], 'radioactivity': [3763], 'liquid': [3767], 'scintillation': [3768], 'counting.': [3769], 'Statistical': [3770, 3787], 'Analysis—Results': [3771], 'represent': [3773], 'means': [3775], 'S.E.': [3777], 'number': [3780], 'experiments': [3782], 'indicated': [3783], 'case.': [3786], "student's": [3792], 't': [3793], 'test.': [3794], 'Interaction': [3795], 'Serotonin': [3800], 'Receptor—We': [3802], 'pathways,': [3815, 3950], 'stimulation': [3817], 'internalization': [3904], '(30Della': [3905], 'wondered': [3939], 'if,': [3940], 'distinct': [3945, 4020], 'might': [3952], 'more': [3955], 'directly': [3964], 'one': [3969], 'domains.': [3973], 'To': [3974], 'end,': [3976], 'immunoprecipitated': [3978], 'fibroblasts': [3984], 'stably': [3989], 'express': [3990], 'levels': [3995], '(36Raymond': [3996], '1991;': [4001], '266:': [4002], '14747-14753Abstract': [4003], 'Fig.': [4013, 4350], '1,': [4014, 4314], 'CaM-specific': [4016], 'antibody': [4017], 'detected': [4018], 'band': [4021, 4037, 4052], '∼19': [4023], 'kDa,': [4024], 'corresponds': [4026], 'Ca2+-bound': [4029], 'mobility': [4030], 'denaturing': [4034], 'conditions.': [4035], 'This': [4036], 'not': [4039], 'present': [4040], 'when': [4041], 'immunoprecipitation': [4042], 'nonspecific-IgG.': [4046], 'similar': [4054], 'slightly': [4057], 'decreased': [4058], 'treated': [4061], 'receptor-selective': [4065], 'agonist': [4066], '8-OH-DPAT.': [4067], 'results': [4069], 'constitutively': [4077], 'complexed': [4078], 'Identification': [4083], 'Putative': [4085], 'Regions': [4088], 'Third': [4091], 'Intracellular': [4092], 'Receptor—Using': [4097], 'computer': [4099, 4353], 'program': [4101], 'identifies': [4103], 'based': [4107, 4264], 'evaluation': [4109], 'criteria': [4110], 'hydropathy,': [4113], 'α-helical': [4114], 'propensity,': [4115], 'residue': [4116, 4120, 4124], 'charge,': [4117], 'helical': [4118], 'class,': [4119], 'weight,': [4121], 'hydrophobic': [4123, 4202, 4270, 4285, 4310], 'content': [4125], '(37Yap': [4126, 4355], 'K.L.': [4127, 4356], 'Kim': [4128, 4357], 'Truong': [4130, 4359], 'Sherman': [4132, 4361], 'Yuan': [4134, 4363], 'Ikura': [4136, 4365], 'Struct.': [4139], 'Funct.': [4140], 'Genomics.': [4141], '1:': [4143], '8-14Crossref': [4144], '(448)': [4147], 'identified': [4151, 4278], 'localized': [4170], 'receptor,': [4178], '(Fig.': [4186, 4318], '2A).': [4187], 'general': [4190], 'rule,': [4191], 'residues': [4203, 4286, 4311], 'interspersed': [4204], 'positively': [4207], 'charged': [4208], 'residues,': [4209], 'often': [4210], 'forming': [4211], 'amphipathic': [4212], 'α-helices': [4213], '(38James': [4214], 'Vorherr': [4216], 'Carafoli': [4218], 'Trends': [4220, 4238], '20:': [4224], '38-42Abstract': [4225], '(346)': [4231], "39O'Neil": [4234], 'K.T.': [4235], '1990;': [4241], '15:': [4242], '59-64Abstract': [4243], '(710)': [4249], 'date': [4257], 'divided': [4260], 'distance': [4267], 'key': [4269, 4284], 'residues.': [4271], '1-12': [4281], 'motif,': [4282, 4307], 'positions': [4288, 4313], '12,': [4291], 'whereas': [4292], 'classified': [4303], '1-8-14': [4306], '8,': [4315], '14': [4317], '2B).': [4319], 'Further': [4320], 'be': [4333], 'aligned': [4334], 'other': [4336, 4343], 'defined': [4338], 'Some': [4345], '2B.': [4351], 'modeling': [4354], 'M': [4366]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2049174331', 'counts_by_year': [{'year': 2023, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-07T21:18:30.135683', 'created_date': '2016-06-24'}