Title: A STUDY OF THE CONTENTS OF THE VESICLES AND PUSTULES OF SMALLPOX.
Abstract:Although we have convincing evidence that the<i>causa causans</i>of smallpox is contained in the purulent contents of the cutaneous lesions, the elusive micro-organism has thus far defied all efforts ...Although we have convincing evidence that the<i>causa causans</i>of smallpox is contained in the purulent contents of the cutaneous lesions, the elusive micro-organism has thus far defied all efforts to establish its identity. The failure to discover the cause of variola has not been due to any inactivity on the part of investigators, for researches in this field have already given rise to a most extensive literature. The bacteriologic investigation of smallpox is indissolubly associated with the study of the cause of vaccinia; according to the most authoritative opinion these two diseases have a common origin, and depend in all probability on the same causative agent. <h3>HISTORICAL SUMMARY.</h3> Sacco, in 1809, was the first to point out the presence in vaccine lymph of motile granules. Since this time scores of investigators have noted the presence of cocci of various kinds in vaccine lymph. In addition, larger roundRead More