Title: Hormone-induced increase of hydroxyindole.O.methyltransferase activity in the embryonic chick pineal gland in organ culture
Abstract: The technique of organ culture was used to investigate the regulation of the increase of hydroxyindole.O.methyltransferase activity of the pineal gland during embryonic development. Glands of 15- and 17-day chick embryos developed small increases of enzyme activity when incubated in organ culture with a standard tissue culture medium. The increase of enzyme activity was markedly stimulated by a combination of hydrocortisone, somatotropin and thyroxine, and simulated the pre-hatch increase found in ovo. All three hormones appeared to be required for consistent development of maximal increases in enzyme activity but none was essential for some increase in activity.
Publication Year: 1979
Publication Date: 1979-03-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 5
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