Title: Combination Atmospheric Pressure Solids Analysis Probe and Desorption Electrospray Ionization Mass Spectrometry Ion Source
Abstract:The atmospheric solids probe analysis (ASAP) probe was investigated as a means for conducting desorption electrospray ionization (DESI) using a commercially available ion source. Solid and liquid samp...The atmospheric solids probe analysis (ASAP) probe was investigated as a means for conducting desorption electrospray ionization (DESI) using a commercially available ion source. Solid and liquid samples as well as a raw urine sample were placed on individual melting point tubes and were inserted into either a heated gas stream for ASAP analysis or a charged solvent spray for DESI-like experiments. Samples ranged in polarity, volatility, mass, (100−17 000 Da), and concentration (neat to submicromolar). Mass spectra of multiple samples were obtained within a single acquisition on a short time scale (<30 s per sample). The configuration of the ion source also allowed rapid switching (∼1 min) between ASAP, electrospray ionization (ESI), and DESI.Read More
Publication Year: 2009
Publication Date: 2009-10-06
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 37
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