Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2048594914', 'doi': 'https://doi.org/10.1089/ham.2005.6.301', 'title': 'Acclimatization to Oxidative Stress at High Altitude', 'display_name': 'Acclimatization to Oxidative Stress at High Altitude', 'publication_year': 2005, 'publication_date': '2005-12-01', 'ids': {'openalex': 'https://openalex.org/W2048594914', 'doi': 'https://doi.org/10.1089/ham.2005.6.301', 'mag': '2048594914', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16351564'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1089/ham.2005.6.301', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S75581497', 'display_name': 'High Altitude Medicine & Biology', 'issn_l': '1527-0297', 'issn': ['1527-0297', '1557-8682'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320443', 'host_organization_name': 'Mary Ann Liebert, Inc.', 'host_organization_lineage': ['https://openalex.org/P4310320443'], 'host_organization_lineage_names': ['Mary Ann Liebert, Inc.'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5049514593', 'display_name': 'Anjana G. Vij', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I51313444', 'display_name': 'Defence Institute of Physiology and Allied Sciences', 'ror': 'https://ror.org/04fzbxp95', 'country_code': 'IN', 'type': 'facility', 'lineage': ['https://openalex.org/I1340206300', 'https://openalex.org/I4210150591', 'https://openalex.org/I51313444']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Anjana G. Vij', 'raw_affiliation_strings': ['Defence Institute of Physiology and Allied Sciences, Delhi, India,'], 'affiliations': [{'raw_affiliation_string': 'Defence Institute of Physiology and Allied Sciences, Delhi, India,', 'institution_ids': ['https://openalex.org/I51313444']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103152587', 'display_name': 'Ruma Dutta', 'orcid': 'https://orcid.org/0000-0002-3637-1618'}, 'institutions': [{'id': 'https://openalex.org/I51313444', 'display_name': 'Defence Institute of Physiology and Allied Sciences', 'ror': 'https://ror.org/04fzbxp95', 'country_code': 'IN', 'type': 'facility', 'lineage': ['https://openalex.org/I1340206300', 'https://openalex.org/I4210150591', 'https://openalex.org/I51313444']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Ruma Dutta', 'raw_affiliation_strings': ['Defence Institute of Physiology and Allied Sciences, Delhi, India,'], 'affiliations': [{'raw_affiliation_string': 'Defence Institute of Physiology and Allied Sciences, Delhi, India,', 'institution_ids': ['https://openalex.org/I51313444']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5006523166', 'display_name': 'Narinder K. Satija', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I51313444', 'display_name': 'Defence Institute of Physiology and Allied Sciences', 'ror': 'https://ror.org/04fzbxp95', 'country_code': 'IN', 'type': 'facility', 'lineage': ['https://openalex.org/I1340206300', 'https://openalex.org/I4210150591', 'https://openalex.org/I51313444']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Narinder K. Satija', 'raw_affiliation_strings': ['Defence Institute of Physiology and Allied Sciences, Delhi, India,'], 'affiliations': [{'raw_affiliation_string': 'Defence Institute of Physiology and Allied Sciences, Delhi, India,', 'institution_ids': ['https://openalex.org/I51313444']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.556, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 60, 'citation_normalized_percentile': {'value': 0.916359, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '6', 'issue': '4', 'first_page': '301', 'last_page': '310'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11968', 'display_name': 'High Altitude and Hypoxia', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11968', 'display_name': 'High Altitude and Hypoxia', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11848', 'display_name': 'Heme Oxygenase-1 and Carbon Monoxide', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11585', 'display_name': 'Exercise and Physiological Responses', 'score': 0.9925, 'subfield': {'id': 'https://openalex.org/subfields/2742', 'display_name': 'Rehabilitation'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/tbars', 'display_name': 'TBARS', 'score': 0.8417578}, {'id': 'https://openalex.org/keywords/thiobarbituric-acid', 'display_name': 'Thiobarbituric acid', 'score': 0.43828762}], 'concepts': [{'id': 'https://openalex.org/C2777352226', 'wikidata': 'https://www.wikidata.org/wiki/Q7669516', 'display_name': 'TBARS', 'level': 4, 'score': 0.8417578}, {'id': 'https://openalex.org/C2776151105', 'wikidata': 'https://www.wikidata.org/wiki/Q898814', 'display_name': 'Oxidative stress', 'level': 2, 'score': 0.80073607}, {'id': 'https://openalex.org/C2986274086', 'wikidata': 'https://www.wikidata.org/wiki/Q199678', 'display_name': 'Ascorbic acid', 'level': 2, 'score': 0.70099473}, {'id': 'https://openalex.org/C2778004101', 'wikidata': 'https://www.wikidata.org/wiki/Q133948', 'display_name': 'Antioxidant', 'level': 2, 'score': 0.63051254}, {'id': 'https://openalex.org/C119406331', 'wikidata': 'https://www.wikidata.org/wiki/Q419763', 'display_name': 'Acclimatization', 'level': 2, 'score': 0.6279062}, {'id': 'https://openalex.org/C2775838275', 'wikidata': 'https://www.wikidata.org/wiki/Q410776', 'display_name': 'Superoxide dismutase', 'level': 3, 'score': 0.60989296}, {'id': 'https://openalex.org/C8240015', 'wikidata': 'https://www.wikidata.org/wiki/Q918226', 'display_name': 'Effects of high altitude on humans', 'level': 2, 'score': 0.5539785}, {'id': 'https://openalex.org/C538909803', 'wikidata': 'https://www.wikidata.org/wiki/Q116907', 'display_name': 'Glutathione', 'level': 3, 'score': 0.5120185}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.50210524}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.44106564}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.44084138}, {'id': 'https://openalex.org/C2777504301', 'wikidata': 'https://www.wikidata.org/wiki/Q418230', 'display_name': 'Thiobarbituric acid', 'level': 4, 'score': 0.43828762}, {'id': 'https://openalex.org/C2780829032', 'wikidata': 'https://www.wikidata.org/wiki/Q898539', 'display_name': 'Lipid peroxidation', 'level': 3, 'score': 0.41818124}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.35558802}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.34806865}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.2827229}, {'id': 'https://openalex.org/C31903555', 'wikidata': 'https://www.wikidata.org/wiki/Q1637030', 'display_name': 'Food science', 'level': 1, 'score': 0.12407911}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.061076134}, {'id': 'https://openalex.org/C18903297', 'wikidata': 'https://www.wikidata.org/wiki/Q7150', 'display_name': 'Ecology', 'level': 1, 'score': 0.051617473}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000064', 'descriptor_name': 'Acclimatization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000532', 'descriptor_name': 'Altitude Sickness', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D000975', 'descriptor_name': 'Antioxidants', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D018384', 'descriptor_name': 'Oxidative Stress', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000208', 'descriptor_name': 'Acute Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000532', 'descriptor_name': 'Altitude Sickness', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000975', 'descriptor_name': 'Antioxidants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006439', 'descriptor_name': 'Hemodynamics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007194', 'descriptor_name': 'India', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018384', 'descriptor_name': 'Oxidative Stress', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1089/ham.2005.6.301', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S75581497', 'display_name': 'High Altitude Medicine & Biology', 'issn_l': '1527-0297', 'issn': ['1527-0297', '1557-8682'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320443', 'host_organization_name': 'Mary Ann Liebert, Inc.', 'host_organization_lineage': ['https://openalex.org/P4310320443'], 'host_organization_lineage_names': ['Mary Ann Liebert, Inc.'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16351564', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Life below water', 'score': 0.88, 'id': 'https://metadata.un.org/sdg/14'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 51, 'referenced_works': ['https://openalex.org/W128213231', 'https://openalex.org/W1589413892', 'https://openalex.org/W1614231230', 'https://openalex.org/W1827540167', 'https://openalex.org/W1859919035', 'https://openalex.org/W1911137613', 'https://openalex.org/W1963820921', 'https://openalex.org/W1963885544', 'https://openalex.org/W1971355916', 'https://openalex.org/W1973993203', 'https://openalex.org/W1974957442', 'https://openalex.org/W1982779076', 'https://openalex.org/W1993730892', 'https://openalex.org/W1994436291', 'https://openalex.org/W1995136950', 'https://openalex.org/W1995517473', 'https://openalex.org/W1996019263', 'https://openalex.org/W2002346300', 'https://openalex.org/W2012231244', 'https://openalex.org/W2017273395', 'https://openalex.org/W2022198234', 'https://openalex.org/W2022303639', 'https://openalex.org/W2028217370', 'https://openalex.org/W2031678443', 'https://openalex.org/W2042430376', 'https://openalex.org/W2043558141', 'https://openalex.org/W2044096147', 'https://openalex.org/W2048569323', 'https://openalex.org/W2053054955', 'https://openalex.org/W2071080907', 'https://openalex.org/W2071758673', 'https://openalex.org/W2076196046', 'https://openalex.org/W2076553390', 'https://openalex.org/W2079321364', 'https://openalex.org/W2083511229', 'https://openalex.org/W2084327512', 'https://openalex.org/W2090851523', 'https://openalex.org/W2102526923', 'https://openalex.org/W2133042655', 'https://openalex.org/W2138064547', 'https://openalex.org/W2142473051', 'https://openalex.org/W2144308706', 'https://openalex.org/W2150539008', 'https://openalex.org/W2161426025', 'https://openalex.org/W2266929960', 'https://openalex.org/W2405134651', 'https://openalex.org/W2416003657', 'https://openalex.org/W2419760473', 'https://openalex.org/W4235808067', 'https://openalex.org/W4239202739', 'https://openalex.org/W89632485'], 'related_works': ['https://openalex.org/W4376270150', 'https://openalex.org/W4300958397', 'https://openalex.org/W3135427317', 'https://openalex.org/W3024122904', 'https://openalex.org/W2380872299', 'https://openalex.org/W2331001191', 'https://openalex.org/W2129170940', 'https://openalex.org/W2093748692', 'https://openalex.org/W2092215721', 'https://openalex.org/W2089604644'], 'abstract_inverted_index': {'Vij,': [0], 'Anjana': [1], 'G.,': [2], 'Ruma': [3], 'Dutta,': [4], 'and': [5, 50, 69, 79, 82, 110, 116, 119, 127, 164, 179, 183, 211, 254], 'Narinder': [6], 'K.': [7], 'Satija.': [8], 'Acclimatization': [9], 'to': [10, 39, 47, 61, 66, 136, 149, 171, 188, 221, 231, 249, 257], 'oxidative': [11, 22, 48, 67, 232, 258], 'stress': [12, 23, 49, 68, 233], 'at': [13, 74, 86, 93, 143, 196], 'high': [14, 31, 40, 197, 222], 'altitude.': [15, 198], 'High': [16], 'Alt.': [17], 'Med.': [18], 'Biol.': [19], '6:301–310,': [20], '2005.—Hypoxia-mediated': [21], 'has': [24], 'been': [25], 'implicated': [26], 'in': [27, 54, 72, 206], 'the': [28, 55, 57, 189, 236, 241], 'pathophysiology': [29], 'of': [30, 176], 'altitude': [32, 41, 87, 223], 'maladaptations.': [33], 'To': [34], 'explore': [35], 'whether': [36], 'prolonged': [37, 219], 'exposure': [38, 220], 'can': [42], 'trigger': [43], 'an': [44, 227, 246], 'adaptive': [45, 229], 'response': [46, 230], 'restore': [51], 'redox': [52], 'homeostasis': [53], 'body,': [56], 'study': [58, 215], 'was': [59, 202], 'conducted': [60], 'evaluate': [62], 'biochemical': [63], 'variables': [64], 'related': [65], 'antioxidant': [70, 122, 154, 237, 242], 'status': [71, 123, 155], 'humans': [73, 224], 'sea': [75, 172], 'level': [76], '(190': [77], 'm)': [78], 'following': [80], '3-': [81], '13-': [83], 'month': [84], 'sojourns': [85], '(4500': [88], 'm).': [89], 'After': [90, 140], '3': [91], 'months': [92, 142], 'altitude,': [94, 144], 'whole-blood': [95], 'thiobarbituric': [96], 'acid': [97, 109, 178], 'reactive': [98], 'substances': [99], '(TBARS)': [100], 'were': [101, 112, 131, 181], 'significantly': [102, 113], 'higher': [103, 185], '(65.6%),': [104], 'nonenzymatic': [105], 'antioxidants': [106], 'like': [107], 'ascorbic': [108, 177], 'caeruloplasmin': [111, 180], 'lower': [114], '(41%': [115], '22%,': [117], 'respectively)': [118], 'plasma': [120, 165], 'total': [121, 153], '(TAS),': [124], 'glutathione': [125, 160], 'levels,': [126], 'superoxide': [128, 208], 'dismutase': [129, 209], 'activity': [130, 210], 'marginally': [132], 'altered': [133], 'as': [134, 169, 186], 'compared': [135, 170, 187], 'their': [137], 'basal': [138], 'values.': [139], '13': [141], 'TBARS': [145], 'levels': [146, 161], 'regressed': [147], 'back': [148], 'preexposure': [150], 'levels.': [151], 'Plasma': [152], '(TAS)': [156], 'improved': [157], 'by': [158, 162, 167, 234], '21%,': [159], '32.8%,': [163], 'bilirubin': [166], '35.8%': [168], 'level.': [173], 'Average': [174], 'concentrations': [175], '18%': [182], '37%': [184], 'subjects': [190], 'studied': [191], 'after': [192], 'a': [193, 203], '3-month': [194], 'stay': [195], 'In': [199], 'addition,': [200], 'there': [201], 'progressive': [204], 'rise': [205], 'erythrocytic': [207], 'persistent': [212], 'hyperurecemia.': [213], 'The': [214], 'observed': [216], 'that': [217], 'on': [218], 'could': [225, 244], 'mount': [226], 'effective': [228, 247], 'activating': [235], 'defense.': [238], 'Hence,': [239], 'strengthening': [240], 'defense': [243], 'be': [245], 'strategy': [248], 'prevent': [250], 'free-radical-mediated': [251], 'pathophysiological': [252], 'alterations': [253], 'quicken': [255], 'acclimatization': [256], 'stress.': [259]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2048594914', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-12T23:27:27.797060', 'created_date': '2016-06-24'}