Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2047546483', 'doi': 'https://doi.org/10.1021/bi00232a031', 'title': "Kinetic parameters for the elimination reaction catalyzed by triosephosphate isomerase and an estimation of the reaction's physiological significance", 'display_name': "Kinetic parameters for the elimination reaction catalyzed by triosephosphate isomerase and an estimation of the reaction's physiological significance", 'publication_year': 1991, 'publication_date': '1991-05-07', 'ids': {'openalex': 'https://openalex.org/W2047546483', 'doi': 'https://doi.org/10.1021/bi00232a031', 'mag': '2047546483', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2021650'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/bi00232a031', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104038378', 'display_name': 'Biochemistry', 'issn_l': '0006-2960', 'issn': ['0006-2960', '1520-4995', '1943-295X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5066402611', 'display_name': 'John P. Richard', 'orcid': 'https://orcid.org/0000-0002-0440-2387'}, 'institutions': [{'id': 'https://openalex.org/I143302722', 'display_name': 'University of Kentucky', 'ror': 'https://ror.org/02k3smh20', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I143302722']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'John P. Richard', 'raw_affiliation_strings': ['Department of Chemistry, University of Kentucky, Lexington 40506-0055'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, University of Kentucky, Lexington 40506-0055', 'institution_ids': ['https://openalex.org/I143302722']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5066402611'], 'corresponding_institution_ids': ['https://openalex.org/I143302722'], 'apc_list': None, 'apc_paid': None, 'fwci': 3.936, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 200, 'citation_normalized_percentile': {'value': 0.985668, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '30', 'issue': '18', 'first_page': '4581', 'last_page': '4585'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12286', 'display_name': 'Erythrocyte Function and Pathophysiology', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12286', 'display_name': 'Erythrocyte Function and Pathophysiology', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12068', 'display_name': 'Neonatal Health and Biochemistry', 'score': 0.9962, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10554', 'display_name': 'Hemoglobinopathies and Related Disorders', 'score': 0.9695, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/triosephosphate-isomerase', 'display_name': 'Triosephosphate isomerase', 'score': 0.9714941}, {'id': 'https://openalex.org/keywords/dihydroxyacetone-phosphate', 'display_name': 'Dihydroxyacetone phosphate', 'score': 0.8756547}, {'id': 'https://openalex.org/keywords/enzyme-kinetics', 'display_name': 'Enzyme Kinetics', 'score': 0.6315277}, {'id': 'https://openalex.org/keywords/glyceraldehyde', 'display_name': 'Glyceraldehyde', 'score': 0.4851416}, {'id': 'https://openalex.org/keywords/reaction-rate', 'display_name': 'Reaction rate', 'score': 0.42599347}, {'id': 'https://openalex.org/keywords/enzyme-catalysis', 'display_name': 'Enzyme Catalysis', 'score': 0.41623902}, {'id': 'https://openalex.org/keywords/dhap', 'display_name': 'DHAP', 'score': 0.413359}], 'concepts': [{'id': 'https://openalex.org/C2778727959', 'wikidata': 'https://www.wikidata.org/wiki/Q24777683', 'display_name': 'Triosephosphate isomerase', 'level': 3, 'score': 0.9714941}, {'id': 'https://openalex.org/C2780866112', 'wikidata': 'https://www.wikidata.org/wiki/Q416915', 'display_name': 'Dihydroxyacetone phosphate', 'level': 3, 'score': 0.8756547}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.78895944}, {'id': 'https://openalex.org/C93391505', 'wikidata': 'https://www.wikidata.org/wiki/Q658700', 'display_name': 'Reaction rate constant', 'level': 3, 'score': 0.70791155}, {'id': 'https://openalex.org/C2777289219', 'wikidata': 'https://www.wikidata.org/wiki/Q7632154', 'display_name': 'Substrate (aquarium)', 'level': 2, 'score': 0.6571906}, {'id': 'https://openalex.org/C56856141', 'wikidata': 'https://www.wikidata.org/wiki/Q883112', 'display_name': 'Enzyme kinetics', 'level': 4, 'score': 0.6315277}, {'id': 'https://openalex.org/C161790260', 'wikidata': 'https://www.wikidata.org/wiki/Q82264', 'display_name': 'Catalysis', 'level': 2, 'score': 0.50970864}, {'id': 'https://openalex.org/C2781272698', 'wikidata': 'https://www.wikidata.org/wiki/Q423211', 'display_name': 'Glyceraldehyde', 'level': 4, 'score': 0.4851416}, {'id': 'https://openalex.org/C2781264208', 'wikidata': 'https://www.wikidata.org/wiki/Q118026', 'display_name': 'Isomerase', 'level': 3, 'score': 0.47032747}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.45632106}, {'id': 'https://openalex.org/C30095370', 'wikidata': 'https://www.wikidata.org/wiki/Q899488', 'display_name': 'Protonation', 'level': 3, 'score': 0.4349867}, {'id': 'https://openalex.org/C175113610', 'wikidata': 'https://www.wikidata.org/wiki/Q3394849', 'display_name': 'Reaction rate', 'level': 3, 'score': 0.42599347}, {'id': 'https://openalex.org/C69118441', 'wikidata': 'https://www.wikidata.org/wiki/Q2941663', 'display_name': 'Enzyme catalysis', 'level': 3, 'score': 0.41623902}, {'id': 'https://openalex.org/C2779617269', 'wikidata': 'https://www.wikidata.org/wiki/Q18015634', 'display_name': 'DHAP', 'level': 3, 'score': 0.413359}, {'id': 'https://openalex.org/C148898269', 'wikidata': 'https://www.wikidata.org/wiki/Q1108792', 'display_name': 'Kinetics', 'level': 2, 'score': 0.39893457}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.39745733}, {'id': 'https://openalex.org/C41183919', 'wikidata': 'https://www.wikidata.org/wiki/Q423026', 'display_name': 'Active site', 'level': 3, 'score': 0.35689417}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.2099899}, {'id': 'https://openalex.org/C2776317432', 'wikidata': 'https://www.wikidata.org/wiki/Q412547', 'display_name': 'Dehydrogenase', 'level': 3, 'score': 0.19543225}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.07095799}, {'id': 'https://openalex.org/C145148216', 'wikidata': 'https://www.wikidata.org/wiki/Q36496', 'display_name': 'Ion', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C18903297', 'wikidata': 'https://www.wikidata.org/wiki/Q7150', 'display_name': 'Ecology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C62520636', 'wikidata': 'https://www.wikidata.org/wiki/Q944', 'display_name': 'Quantum mechanics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D009132', 'descriptor_name': 'Muscles', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D014305', 'descriptor_name': 'Triose-Phosphate Isomerase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004099', 'descriptor_name': 'Dihydroxyacetone Phosphate', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004099', 'descriptor_name': 'Dihydroxyacetone Phosphate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005986', 'descriptor_name': 'Glyceraldehyde 3-Phosphate', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005986', 'descriptor_name': 'Glyceraldehyde 3-Phosphate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007791', 'descriptor_name': 'Lactoylglutathione Lyase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007791', 'descriptor_name': 'Lactoylglutathione Lyase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009132', 'descriptor_name': 'Muscles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011765', 'descriptor_name': 'Pyruvaldehyde', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011765', 'descriptor_name': 'Pyruvaldehyde', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011817', 'descriptor_name': 'Rabbits', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013869', 'descriptor_name': 'Thiolester Hydrolases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013869', 'descriptor_name': 'Thiolester Hydrolases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014305', 'descriptor_name': 'Triose-Phosphate Isomerase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014305', 'descriptor_name': 'Triose-Phosphate Isomerase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/bi00232a031', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104038378', 'display_name': 'Biochemistry', 'issn_l': '0006-2960', 'issn': ['0006-2960', '1520-4995', '1943-295X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2021650', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 27, 'referenced_works': ['https://openalex.org/W106577432', 'https://openalex.org/W1485363919', 'https://openalex.org/W1501510468', 'https://openalex.org/W1506579504', 'https://openalex.org/W1535005019', 'https://openalex.org/W1541556471', 'https://openalex.org/W1542070333', 'https://openalex.org/W1542496341', 'https://openalex.org/W1974873606', 'https://openalex.org/W1985066480', 'https://openalex.org/W2023688586', 'https://openalex.org/W2026019482', 'https://openalex.org/W2036156471', 'https://openalex.org/W2046696671', 'https://openalex.org/W2052536323', 'https://openalex.org/W2063539499', 'https://openalex.org/W2067402940', 'https://openalex.org/W2079490993', 'https://openalex.org/W2089863436', 'https://openalex.org/W2095098723', 'https://openalex.org/W2095237995', 'https://openalex.org/W2200018599', 'https://openalex.org/W2306066944', 'https://openalex.org/W2321274769', 'https://openalex.org/W2329265014', 'https://openalex.org/W2950310426', 'https://openalex.org/W90656072'], 'related_works': ['https://openalex.org/W2265730753', 'https://openalex.org/W2137086924', 'https://openalex.org/W2088699662', 'https://openalex.org/W2067402940', 'https://openalex.org/W2030448843', 'https://openalex.org/W2004764839', 'https://openalex.org/W1999979854', 'https://openalex.org/W1984539952', 'https://openalex.org/W177751858', 'https://openalex.org/W1015683091'], 'abstract_inverted_index': {'ADVERTISEMENT': [0], 'RETURN': [1], 'TO': [2], 'ISSUEPREVArticleNEXTKinetic': [3], 'parameters': [4], 'for': [5, 147], 'the': [6, 17, 51, 82, 87, 116, 127, 140, 143, 148, 155, 161], 'elimination': [7], 'reaction': [8], 'catalyzed': [9], 'by': [10, 96], 'triosephosphate': [11], 'isomerase': [12], 'and': [13, 64, 69, 98, 142, 159, 175, 177], 'an': [14], 'estimation': [15], 'of': [16, 54, 89, 115], "reaction's": [18], 'physiological': [19], 'significanceJohn': [20], 'P.': [21], 'RichardCite': [22], 'this:': [23], 'Biochemistry': [24], '1991,': [25], '30,': [26], '18,': [27], '4581–4585Publication': [28], 'Date': [29], '(Print):May': [30], '7,': [31], '1991Publication': [32], 'History': [33], 'Published': [34], 'online1': [35], 'May': [36, 40], '2002Published': [37], 'inissue': [38], '7': [39], '1991https://pubs.acs.org/doi/10.1021/bi00232a031https://doi.org/10.1021/bi00232a031research-articleACS': [41], 'PublicationsRequest': [42], 'reuse': [43], 'permissionsArticle': [44], 'Views789Altmetric-Citations166LEARN': [45], 'ABOUT': [46], 'THESE': [47], 'METRICSArticle': [48], 'Views': [49], 'are': [50, 73, 86], 'COUNTER-compliant': [52], 'sum': [53], 'full': [55], 'text': [56], 'article': [57, 121], 'downloads': [58], 'since': [59], 'November': [60], '2008': [61], '(both': [62], 'PDF': [63], 'HTML)': [65], 'across': [66], 'all': [67], 'institutions': [68], 'individuals.': [70], 'These': [71], 'metrics': [72], 'regularly': [74], 'updated': [75, 99], 'to': [76, 81], 'reflect': [77], 'usage': [78], 'leading': [79], 'up': [80], 'last': [83], 'few': [84], 'days.Citations': [85], 'number': [88], 'other': [90], 'articles': [91], 'citing': [92], 'this': [93], 'article,': [94], 'calculated': [95], 'Crossref': [97, 105], 'daily.': [100], 'Find': [101, 151], 'more': [102, 152], 'information': [103, 153], 'about': [104, 139], 'citation': [106], 'counts.The': [107], 'Altmetric': [108, 156], 'Attention': [109, 157], 'Score': [110, 158], 'is': [111, 163], 'a': [112, 119, 132], 'quantitative': [113], 'measure': [114], 'attention': [117], 'that': [118], 'research': [120], 'has': [122], 'received': [123], 'online.': [124], 'Clicking': [125], 'on': [126, 154], 'donut': [128], 'icon': [129], 'will': [130], 'load': [131], 'page': [133], 'at': [134], 'altmetric.com': [135], 'with': [136, 171], 'additional': [137], 'details': [138], 'score': [141, 162], 'social': [144], 'media': [145], 'presence': [146], 'given': [149], 'article.': [150], 'how': [160], 'calculated.': [164], 'Share': [165, 180], 'Add': [166], 'toView': [167], 'InAdd': [168], 'Full': [169], 'Text': [170], 'ReferenceAdd': [172], 'Description': [173], 'ExportRISCitationCitation': [174], 'abstractCitation': [176], 'referencesMore': [178], 'Options': [179], 'onFacebookTwitterWechatLinked': [181], 'InRedditEmail': [182], 'Other': [183], 'access': [184], 'optionsGet': [185], 'e-Alertsclose': [186], 'Get': [187], 'e-Alerts': [188]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2047546483', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 8}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-07T22:49:29.383899', 'created_date': '2016-06-24'}