Publication Information

{'id': 'https://openalex.org/W204747089', 'doi': 'https://doi.org/10.1042/bj2150133', 'title': 'Dual role of a single multienzyme complex in the oxidative decarboxylation of pyruvate and branched-chain 2-oxo acids in <i>Bacillus subtilis</i>', 'display_name': 'Dual role of a single multienzyme complex in the oxidative decarboxylation of pyruvate and branched-chain 2-oxo acids in <i>Bacillus subtilis</i>', 'publication_year': 1983, 'publication_date': '1983-10-01', 'ids': {'openalex': 'https://openalex.org/W204747089', 'doi': 'https://doi.org/10.1042/bj2150133', 'mag': '204747089', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/6414463', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1152372'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bj2150133', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S44425019', 'display_name': 'Biochemical Journal', 'issn_l': '0264-6021', 'issn': ['0264-6021', '1470-8728'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc1152372?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5110651551', 'display_name': 'Peter N. Lowe', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I181647926', 'display_name': 'University of Strathclyde', 'ror': 'https://ror.org/00n3w3b69', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I181647926']}, {'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}, {'id': 'https://openalex.org/I87048295', 'display_name': 'Wellcome Trust', 'ror': 'https://ror.org/029chgv08', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I87048295']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'P N Lowe', 'raw_affiliation_strings': ['Department of Biochemical Parasitology, The Wellcome Research Laboratories, Langley Court, Beckenham, Kent BR3 3BS, U.K.', 'Department of Bioscience and Biotechnology, Applied Microbiology Division, University of Strathclyde, 204 George Street, Glasgow GI lXW, Scotland, U.K.', 'Department ofBiochemistry, University ofCambridge, Tennis Court Road, Cambridge CB2 IQ W, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Department of Bioscience and Biotechnology, Applied Microbiology Division, University of Strathclyde, 204 George Street, Glasgow GI lXW, Scotland, U.K.', 'institution_ids': ['https://openalex.org/I181647926']}, {'raw_affiliation_string': 'Department ofBiochemistry, University ofCambridge, Tennis Court Road, Cambridge CB2 IQ W, U.K.', 'institution_ids': ['https://openalex.org/I241749']}, {'raw_affiliation_string': 'Department of Biochemical Parasitology, The Wellcome Research Laboratories, Langley Court, Beckenham, Kent BR3 3BS, U.K.', 'institution_ids': ['https://openalex.org/I87048295']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110483139', 'display_name': 'J. A. HODGSON', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I181647926', 'display_name': 'University of Strathclyde', 'ror': 'https://ror.org/00n3w3b69', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I181647926']}, {'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}, {'id': 'https://openalex.org/I87048295', 'display_name': 'Wellcome Trust', 'ror': 'https://ror.org/029chgv08', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I87048295']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'J A Hodgson', 'raw_affiliation_strings': ['Department of Biochemical Parasitology, The Wellcome Research Laboratories, Langley Court, Beckenham, Kent BR3 3BS, U.K.', 'Department of Bioscience and Biotechnology, Applied Microbiology Division, University of Strathclyde, 204 George Street, Glasgow GI lXW, Scotland, U.K.', 'Department ofBiochemistry, University ofCambridge, Tennis Court Road, Cambridge CB2 IQ W, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Department of Bioscience and Biotechnology, Applied Microbiology Division, University of Strathclyde, 204 George Street, Glasgow GI lXW, Scotland, U.K.', 'institution_ids': ['https://openalex.org/I181647926']}, {'raw_affiliation_string': 'Department ofBiochemistry, University ofCambridge, Tennis Court Road, Cambridge CB2 IQ W, U.K.', 'institution_ids': ['https://openalex.org/I241749']}, {'raw_affiliation_string': 'Department of Biochemical Parasitology, The Wellcome Research Laboratories, Langley Court, Beckenham, Kent BR3 3BS, U.K.', 'institution_ids': ['https://openalex.org/I87048295']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5108288766', 'display_name': 'Richard N. Perham', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I181647926', 'display_name': 'University of Strathclyde', 'ror': 'https://ror.org/00n3w3b69', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I181647926']}, {'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}, {'id': 'https://openalex.org/I87048295', 'display_name': 'Wellcome Trust', 'ror': 'https://ror.org/029chgv08', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I87048295']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'R N Perham', 'raw_affiliation_strings': ['Department of Biochemical Parasitology, The Wellcome Research Laboratories, Langley Court, Beckenham, Kent BR3 3BS, U.K.', 'Department of Bioscience and Biotechnology, Applied Microbiology Division, University of Strathclyde, 204 George Street, Glasgow GI lXW, Scotland, U.K.', 'Department ofBiochemistry, University ofCambridge, Tennis Court Road, Cambridge CB2 IQ W, U.K.'], 'affiliations': [{'raw_affiliation_string': 'Department of Bioscience and Biotechnology, Applied Microbiology Division, University of Strathclyde, 204 George Street, Glasgow GI lXW, Scotland, U.K.', 'institution_ids': ['https://openalex.org/I181647926']}, {'raw_affiliation_string': 'Department ofBiochemistry, University ofCambridge, Tennis Court Road, Cambridge CB2 IQ W, U.K.', 'institution_ids': ['https://openalex.org/I241749']}, {'raw_affiliation_string': 'Department of Biochemical Parasitology, The Wellcome Research Laboratories, Langley Court, Beckenham, Kent BR3 3BS, U.K.', 'institution_ids': ['https://openalex.org/I87048295']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.32, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 68, 'citation_normalized_percentile': {'value': 0.950617, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '215', 'issue': '1', 'first_page': '133', 'last_page': '140'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12770', 'display_name': 'Amino Acid Enzymes and Metabolism', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12770', 'display_name': 'Amino Acid Enzymes and Metabolism', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12915', 'display_name': 'Biochemical Acid Research Studies', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11162', 'display_name': 'Enzyme Structure and Function', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/2505', 'display_name': 'Materials Chemistry'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dihydrolipoyl-transacetylase', 'display_name': 'Dihydrolipoyl transacetylase', 'score': 0.9148096}, {'id': 'https://openalex.org/keywords/oxoglutarate-dehydrogenase-complex', 'display_name': 'Oxoglutarate dehydrogenase complex', 'score': 0.7638328}, {'id': 'https://openalex.org/keywords/oxidative-decarboxylation', 'display_name': 'Oxidative decarboxylation', 'score': 0.6371254}, {'id': 'https://openalex.org/keywords/dihydrolipoamide-dehydrogenase', 'display_name': 'Dihydrolipoamide dehydrogenase', 'score': 0.51833546}], 'concepts': [{'id': 'https://openalex.org/C88099638', 'wikidata': 'https://www.wikidata.org/wiki/Q412856', 'display_name': 'Pyruvate dehydrogenase complex', 'level': 3, 'score': 0.93006235}, {'id': 'https://openalex.org/C80097345', 'wikidata': 'https://www.wikidata.org/wiki/Q419036', 'display_name': 'Dihydrolipoyl transacetylase', 'level': 5, 'score': 0.9148096}, {'id': 'https://openalex.org/C151325109', 'wikidata': 'https://www.wikidata.org/wiki/Q22327132', 'display_name': 'Branched-chain alpha-keto acid dehydrogenase complex', 'level': 4, 'score': 0.8785458}, {'id': 'https://openalex.org/C190098323', 'wikidata': 'https://www.wikidata.org/wiki/Q14912712', 'display_name': 'Pyruvate dehydrogenase phosphatase', 'level': 4, 'score': 0.8432374}, {'id': 'https://openalex.org/C101972281', 'wikidata': 'https://www.wikidata.org/wiki/Q899965', 'display_name': 'Pyruvate decarboxylation', 'level': 4, 'score': 0.76799583}, {'id': 'https://openalex.org/C126093377', 'wikidata': 'https://www.wikidata.org/wiki/Q309518', 'display_name': 'Oxoglutarate dehydrogenase complex', 'level': 5, 'score': 0.7638328}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.7440124}, {'id': 'https://openalex.org/C9506865', 'wikidata': 'https://www.wikidata.org/wiki/Q6321025', 'display_name': 'Pyruvate dehydrogenase kinase', 'level': 4, 'score': 0.7403176}, {'id': 'https://openalex.org/C179402230', 'wikidata': 'https://www.wikidata.org/wiki/Q14865383', 'display_name': 'Pyruvate dehydrogenase lipoamide kinase isozyme 1', 'level': 5, 'score': 0.655833}, {'id': 'https://openalex.org/C2779634684', 'wikidata': 'https://www.wikidata.org/wiki/Q3818578', 'display_name': 'Oxidative decarboxylation', 'level': 3, 'score': 0.6371254}, {'id': 'https://openalex.org/C2776317432', 'wikidata': 'https://www.wikidata.org/wiki/Q412547', 'display_name': 'Dehydrogenase', 'level': 3, 'score': 0.5266359}, {'id': 'https://openalex.org/C120763696', 'wikidata': 'https://www.wikidata.org/wiki/Q419337', 'display_name': 'Dihydrolipoamide dehydrogenase', 'level': 4, 'score': 0.51833546}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4300001}, {'id': 'https://openalex.org/C165135838', 'wikidata': 'https://www.wikidata.org/wiki/Q133895', 'display_name': 'Citric acid cycle', 'level': 3, 'score': 0.41718197}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.398788}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.23141316}], 'mesh': [{'descriptor_ui': 'D001412', 'descriptor_name': 'Bacillus subtilis', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D007658', 'descriptor_name': 'Ketone Oxidoreductases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009097', 'descriptor_name': 'Multienzyme Complexes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011768', 'descriptor_name': 'Pyruvate Dehydrogenase Complex', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D042942', 'descriptor_name': '3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001412', 'descriptor_name': 'Bacillus subtilis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001412', 'descriptor_name': 'Bacillus subtilis', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D001412', 'descriptor_name': 'Bacillus subtilis', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D003653', 'descriptor_name': 'Decarboxylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007658', 'descriptor_name': 'Ketone Oxidoreductases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007658', 'descriptor_name': 'Ketone Oxidoreductases', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009097', 'descriptor_name': 'Multienzyme Complexes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009097', 'descriptor_name': 'Multienzyme Complexes', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010084', 'descriptor_name': 'Oxidation-Reduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011768', 'descriptor_name': 'Pyruvate Dehydrogenase Complex', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011768', 'descriptor_name': 'Pyruvate Dehydrogenase Complex', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bj2150133', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S44425019', 'display_name': 'Biochemical Journal', 'issn_l': '0264-6021', 'issn': ['0264-6021', '1470-8728'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1152372', 'pdf_url': 'https://europepmc.org/articles/pmc1152372?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1152372', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/6414463', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1152372', 'pdf_url': 'https://europepmc.org/articles/pmc1152372?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Clean water and sanitation', 'score': 0.43, 'id': 'https://metadata.un.org/sdg/6'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 20, 'referenced_works': ['https://openalex.org/W1488217721', 'https://openalex.org/W1488365067', 'https://openalex.org/W1503256853', 'https://openalex.org/W1553661888', 'https://openalex.org/W1562347249', 'https://openalex.org/W1587473926', 'https://openalex.org/W1595387542', 'https://openalex.org/W1619234571', 'https://openalex.org/W16358976', 'https://openalex.org/W1800196134', 'https://openalex.org/W1991727789', 'https://openalex.org/W2007568727', 'https://openalex.org/W2013004671', 'https://openalex.org/W2021997260', 'https://openalex.org/W2106359341', 'https://openalex.org/W2160307752', 'https://openalex.org/W2334169074', 'https://openalex.org/W2407356409', 'https://openalex.org/W2408748654', 'https://openalex.org/W2417900331'], 'related_works': ['https://openalex.org/W4230390448', 'https://openalex.org/W320461670', 'https://openalex.org/W2369281961', 'https://openalex.org/W2184209744', 'https://openalex.org/W204747089', 'https://openalex.org/W2015269539', 'https://openalex.org/W2000725524', 'https://openalex.org/W1975622822', 'https://openalex.org/W1516242195', 'https://openalex.org/W1490403537'], 'abstract_inverted_index': {'The': [0, 78, 105], 'pyruvate': [1, 29, 39, 69, 79, 114, 184], 'dehydrogenase': [2, 7, 34, 40, 49, 70, 75, 80, 85, 117, 122, 161, 185, 190], 'and': [3, 32, 71, 81, 98, 102, 118, 127, 153, 186], 'branched-chain': [4, 46, 72, 82, 119, 187], '2-oxo': [5, 47, 73, 83, 120, 188], 'acid': [6, 48, 74, 84, 121, 189], 'activities': [8], 'of': [9, 22, 37, 54, 87, 132, 176, 199, 204], 'Bacillus': [10], 'subtilis': [11, 24, 89], 'were': [12, 42], 'found': [13], 'to': [14, 65, 109, 128, 143, 168], 'co-purify': [15], 'as': [16, 195], 'a': [17, 133, 177], 'single': [18, 134, 183], 'multienzyme': [19], 'complex.': [20], 'Mutants': [21], 'B.': [23, 88, 151], 'with': [25], 'defects': [26], 'in': [27, 45, 62, 68, 124, 150, 179], 'the': [28, 38, 55, 91, 103, 113, 130, 158, 173], 'decarboxylase': [30], '(E1)': [31], 'dihydrolipoamide': [33], '(E3)': [35], 'components': [36, 61], 'complex': [41, 50, 76, 191], 'correspondingly': [43], 'affected': [44], 'activity.': [51, 77], 'Selective': [52], 'inhibition': [53], 'E1': [56], 'or': [57], 'lipoate': [58], 'acetyltransferase': [59], '(E2)': [60], 'vitro': [63], 'led': [64], 'parallel': [66], 'losses': [67], 'complexes': [86, 123], 'at': [90], 'very': [92], 'least': [93], 'share': [94], 'many': [95], 'structural': [96, 135], 'components,': [97], 'are': [99, 141], 'probably': [100], 'one': [101], 'same.': [104], 'E3': [106], 'component': [107], 'appeared': [108], 'be': [110, 129, 144, 193], 'identical': [111], 'for': [112, 146], 'dehydrogenase,': [115], '2-oxoglutarate': [116], 'this': [125], 'organism': [126], 'product': [131], 'gene.': [136], 'Long-chain': [137], 'branched': [138], 'fatty': [139], 'acids': [140], 'thought': [142], 'essential': [145, 205], 'maintaining': [147], 'membrane': [148, 180], 'fluidity': [149], 'subtilis,': [152], 'it': [154], 'was': [155, 165], 'observed': [156], 'that': [157], 'ace': [159], '(pyruvate': [160], 'complex)': [162], 'mutant': [163], '61142': [164], 'unable': [166], 'rapidly': [167], 'take': [169], 'up': [170], 'acetoacetate,': [171], 'unlike': [172], 'wild-type,': [174], 'indicative': [175], 'defect': [178], 'permeability.': [181], 'A': [182], 'can': [192], 'seen': [194], 'an': [196], 'economical': [197], 'means': [198], 'supplying': [200], 'two': [201], 'different': [202], 'sets': [203], 'metabolites.': [206]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W204747089', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-12T21:40:37.917129', 'created_date': '2016-06-24'}