Title: Synthesis of enantiomerically enriched α-trifluoromethylated acids, esters and ketones
Abstract: α-Trifluoromethylated carboxylic acids have been obtained with high optical purity by enzymatic hydrolysis. Further, the synthesis of optically active α-trifluoromethylated ketones by the thermolysis of diallyl alcohols, produced from the reaction of Grignard reagent and optically pure α-trifluoromethylated carboxylic acid ethyl esters, is described.
Publication Year: 1992
Publication Date: 1992-11-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 8
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