Diffusion Tensor Imaging (DTI) in idiopathic REM sleep behaviour disorder (iRBD)

Name: Work Video:
Duration: 3 min 30 s
Description: Idiopathic REM sleep behaviour disorder (iRBD) – a parasomnia characterized by dream enactments – is a risk factor for the development of Parkinson's disease (PD) and other alpha-synucleinopathies. The pathophysiology of iRBD is likely due to dysfunction of brainstem nuclei that regulate REM sleep.
Marcus Belke; MM Unger; K Hattemer; JT Heverhagen; Boris Keil; Karin Stiasny‐Kolster; Felix Rosenow; NJ Diederich; Geert Mayer; J. Carsten Möller; WH Oertel; Susanne Knake
{'id': 'https://openalex.org/W2046493858', 'doi': 'https://doi.org/10.1055/s-0030-1250965', 'title': 'Diffusion Tensor Imaging (DTI) in idiopathic REM sleep behaviour disorder (iRBD)', 'display_name': 'Diffusion Tensor Imaging (DTI) in idiopathic REM sleep behaviour disorder (iRBD)', 'publication_year': 2010, 'publication_date': '2010-03-01', 'ids': {'openalex': 'https://openalex.org/W2046493858', 'doi': 'https://doi.org/10.1055/s-0030-1250965', 'mag': '2046493858'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1055/s-0030-1250965', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S44826309', 'display_name': 'Klinische Neurophysiologie', 'issn_l': '1434-0275', 'issn': ['1434-0275', '1439-4081'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310321135', 'host_organization_name': 'Georg Thieme Verlag', 'host_organization_lineage': ['https://openalex.org/P4310321135', 'https://openalex.org/P4310320000'], 'host_organization_lineage_names': ['Georg Thieme Verlag', 'Thieme Medical Publishers (Germany)'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5039233902', 'display_name': 'Marcus Belke', 'orcid': 'https://orcid.org/0000-0001-5131-1579'}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'M Belke', 'raw_affiliation_strings': ['Philipps Universität Marburg, Neurologie, Marburg, Deutschland'], 'affiliations': [{'raw_affiliation_string': 'Philipps Universität Marburg, Neurologie, Marburg, Deutschland', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020260662', 'display_name': 'MM Unger', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'MM Unger', 'raw_affiliation_strings': ['Philipps Universität Marburg, Neurologie, Marburg, Deutschland'], 'affiliations': [{'raw_affiliation_string': 'Philipps Universität Marburg, Neurologie, Marburg, Deutschland', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023649328', 'display_name': 'K Hattemer', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'K Hattemer', 'raw_affiliation_strings': ['Philipps Universität Marburg, Neurologie, Marburg, Deutschland'], 'affiliations': [{'raw_affiliation_string': 'Philipps Universität Marburg, Neurologie, Marburg, Deutschland', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103428391', 'display_name': 'JT Heverhagen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'JT Heverhagen', 'raw_affiliation_strings': ['Philipps-Universität Marburg, Department of Diagnostic Radiology, Marburg, Deutschland'], 'affiliations': [{'raw_affiliation_string': 'Philipps-Universität Marburg, Department of Diagnostic Radiology, Marburg, Deutschland', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072560130', 'display_name': 'Boris Keil', 'orcid': 'https://orcid.org/0000-0003-0805-8330'}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'B Keil', 'raw_affiliation_strings': ['Philipps-Universität Marburg, Department of Diagnostic Radiology, Marburg, Deutschland'], 'affiliations': [{'raw_affiliation_string': 'Philipps-Universität Marburg, Department of Diagnostic Radiology, Marburg, Deutschland', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065223531', 'display_name': 'Karin Stiasny‐Kolster', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'K Stiasny-Kolster', 'raw_affiliation_strings': ['Philipps Universität Marburg, Neurologie, Marburg, Deutschland'], 'affiliations': [{'raw_affiliation_string': 'Philipps Universität Marburg, Neurologie, Marburg, Deutschland', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054670691', 'display_name': 'Felix Rosenow', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'F Rosenow', 'raw_affiliation_strings': ['Philipps Universität Marburg, Neurologie, Marburg, Deutschland'], 'affiliations': [{'raw_affiliation_string': 'Philipps Universität Marburg, Neurologie, Marburg, Deutschland', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089079189', 'display_name': 'NJ Diederich', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I162487826', 'display_name': 'Centre Hospitalier de Luxembourg', 'ror': 'https://ror.org/03xq7w797', 'country_code': 'LU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I162487826']}], 'countries': ['LU'], 'is_corresponding': False, 'raw_author_name': 'NJ Diederich', 'raw_affiliation_strings': ['Centre Hospitalier de Luxembourg, Department of Neurosciences, Luxembourg, Luxembourg'], 'affiliations': [{'raw_affiliation_string': 'Centre Hospitalier de Luxembourg, Department of Neurosciences, Luxembourg, Luxembourg', 'institution_ids': ['https://openalex.org/I162487826']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000989945', 'display_name': 'Geert Mayer', 'orcid': 'https://orcid.org/0000-0002-5147-4383'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'G Mayer', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015411956', 'display_name': 'J. Carsten Möller', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'JC Möller', 'raw_affiliation_strings': ['Philipps Universität Marburg, Neurologie, Marburg, Deutschland'], 'affiliations': [{'raw_affiliation_string': 'Philipps Universität Marburg, Neurologie, Marburg, Deutschland', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073027634', 'display_name': 'WH Oertel', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'WH Oertel', 'raw_affiliation_strings': ['Philipps Universität Marburg, Neurologie, Marburg, Deutschland'], 'affiliations': [{'raw_affiliation_string': 'Philipps Universität Marburg, Neurologie, Marburg, Deutschland', 'institution_ids': ['https://openalex.org/I161103922']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5015701509', 'display_name': 'Susanne Knake', 'orcid': 'https://orcid.org/0000-0002-6298-0513'}, 'institutions': [{'id': 'https://openalex.org/I161103922', 'display_name': 'Philipps University of Marburg', 'ror': 'https://ror.org/01rdrb571', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I161103922']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'S Knake', 'raw_affiliation_strings': ['Philipps Universität Marburg, Neurologie, Marburg, Deutschland'], 'affiliations': [{'raw_affiliation_string': 'Philipps Universität Marburg, Neurologie, Marburg, Deutschland', 'institution_ids': ['https://openalex.org/I161103922']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.566156, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 71, 'max': 75}, 'biblio': {'volume': '41', 'issue': '01', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10085', 'display_name': "Parkinson's Disease Mechanisms and Treatments", 'score': 0.9916, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10085', 'display_name': "Parkinson's Disease Mechanisms and Treatments", 'score': 0.9916, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10919', 'display_name': 'Neurological disorders and treatments', 'score': 0.9272, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/parasomnia', 'display_name': 'Parasomnia', 'score': 0.91986096}, {'id': 'https://openalex.org/keywords/synucleinopathies', 'display_name': 'Synucleinopathies', 'score': 0.7062619}, {'id': 'https://openalex.org/keywords/sleep', 'display_name': 'Sleep', 'score': 0.46116728}, {'id': 'https://openalex.org/keywords/restless-legs-syndrome', 'display_name': 'Restless Legs Syndrome', 'score': 0.4328096}], 'concepts': [{'id': 'https://openalex.org/C2780228687', 'wikidata': 'https://www.wikidata.org/wiki/Q559869', 'display_name': 'Parasomnia', 'level': 4, 'score': 0.91986096}, {'id': 'https://openalex.org/C2776132596', 'wikidata': 'https://www.wikidata.org/wiki/Q2103933', 'display_name': 'REM sleep behavior disorder', 'level': 4, 'score': 0.91503453}, {'id': 'https://openalex.org/C2777440831', 'wikidata': 'https://www.wikidata.org/wiki/Q2376264', 'display_name': 'Synucleinopathies', 'level': 5, 'score': 0.7062619}, {'id': 'https://openalex.org/C551621295', 'wikidata': 'https://www.wikidata.org/wiki/Q182228', 'display_name': 'Brainstem', 'level': 2, 'score': 0.57963187}, {'id': 'https://openalex.org/C149550507', 'wikidata': 'https://www.wikidata.org/wiki/Q899360', 'display_name': 'Diffusion MRI', 'level': 3, 'score': 0.5613498}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.55689335}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.5248404}, {'id': 'https://openalex.org/C2775841894', 'wikidata': 'https://www.wikidata.org/wiki/Q4683692', 'display_name': 'Sleep (system call)', 'level': 2, 'score': 0.46116728}, {'id': 'https://openalex.org/C2776750294', 'wikidata': 'https://www.wikidata.org/wiki/Q916280', 'display_name': 'Restless legs syndrome', 'level': 3, 'score': 0.4328096}, {'id': 'https://openalex.org/C2781095916', 'wikidata': 'https://www.wikidata.org/wiki/Q36348', 'display_name': 'Dream', 'level': 2, 'score': 0.43203205}, {'id': 'https://openalex.org/C20566671', 'wikidata': 'https://www.wikidata.org/wiki/Q1752878', 'display_name': 'Non-rapid eye movement sleep', 'level': 3, 'score': 0.42561805}, {'id': 'https://openalex.org/C2779734285', 'wikidata': 'https://www.wikidata.org/wiki/Q11085', 'display_name': "Parkinson's disease", 'level': 3, 'score': 0.4244467}, {'id': 'https://openalex.org/C2778205975', 'wikidata': 'https://www.wikidata.org/wiki/Q1754874', 'display_name': 'Polysomnography', 'level': 3, 'score': 0.39961737}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.38511944}, {'id': 'https://openalex.org/C2781449126', 'wikidata': 'https://www.wikidata.org/wiki/Q288591', 'display_name': 'Alpha-synuclein', 'level': 4, 'score': 0.3636127}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.35784054}, {'id': 'https://openalex.org/C16568411', 'wikidata': 'https://www.wikidata.org/wiki/Q83042', 'display_name': 'Neurology', 'level': 2, 'score': 0.33600354}, {'id': 'https://openalex.org/C522805319', 'wikidata': 'https://www.wikidata.org/wiki/Q179965', 'display_name': 'Electroencephalography', 'level': 2, 'score': 0.30145624}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.18065101}, {'id': 'https://openalex.org/C143409427', 'wikidata': 'https://www.wikidata.org/wiki/Q161238', 'display_name': 'Magnetic resonance imaging', 'level': 2, 'score': 0.17151779}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C126838900', 'wikidata': 'https://www.wikidata.org/wiki/Q77604', 'display_name': 'Radiology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C111919701', 'wikidata': 'https://www.wikidata.org/wiki/Q9135', 'display_name': 'Operating system', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1055/s-0030-1250965', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S44826309', 'display_name': 'Klinische Neurophysiologie', 'issn_l': '1434-0275', 'issn': ['1434-0275', '1439-4081'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310321135', 'host_organization_name': 'Georg Thieme Verlag', 'host_organization_lineage': ['https://openalex.org/P4310321135', 'https://openalex.org/P4310320000'], 'host_organization_lineage_names': ['Georg Thieme Verlag', 'Thieme Medical Publishers (Germany)'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.54, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4385350318', 'https://openalex.org/W4298848774', 'https://openalex.org/W4239149489', 'https://openalex.org/W3186279298', 'https://openalex.org/W2892371184', 'https://openalex.org/W2800027468', 'https://openalex.org/W2768364432', 'https://openalex.org/W2413600617', 'https://openalex.org/W2340001262', 'https://openalex.org/W1993332294'], 'abstract_inverted_index': {'Idiopathic': [0], 'REM': [1, 42], 'sleep': [2], 'behaviour': [3], 'disorder': [4], '(iRBD)': [5], '–': [6, 13], 'a': [7, 15], 'parasomnia': [8], 'characterized': [9], 'by': [10], 'dream': [11], 'enactments': [12], 'is': [14, 32], 'risk': [16], 'factor': [17], 'for': [18], 'the': [19], 'development': [20], 'of': [21, 30, 37], "Parkinson's": [22], 'disease': [23], '(PD)': [24], 'and': [25], 'other': [26], 'alpha-synucleinopathies.': [27], 'The': [28], 'pathophysiology': [29], 'iRBD': [31], 'likely': [33], 'due': [34], 'to': [35], 'dysfunction': [36], 'brainstem': [38], 'nuclei': [39], 'that': [40], 'regulate': [41], 'sleep.': [43]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2046493858', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}], 'updated_date': '2024-12-11T13:35:43.729181', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
