Title: Leucine, isoleucine and valine relationships in the rat
Abstract: Previous work had demonstrated that leucine fed to rats increased the requirement for isoleucine but, when 3% of l-leucine was fed, isoleucine only partially overcame the growth depression. It has now been shown that a supplement of valine was necessary to restore the rate of growth. Valine, isoleucine, and phenylalanine have been shown to reduce the utilization of leucine for the growth of rats fed a 9% casein diet supplemented with a number of amino acids. By using this diet and varying the levels of leucine, valine, isoleucine, and phenylalanine, evidence has been obtained for antagonisms between isoleucine and valine, between phenylalanine and isoleucine, and between phenylalanine and valine. It is suggested that antagonisms between each of these pairs of amino acids may be found under the proper dietary conditions.
Publication Year: 1956
Publication Date: 1956-01-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 92
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