Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2044911975', 'doi': 'https://doi.org/10.1016/j.devcel.2012.01.003', 'title': 'Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway', 'display_name': 'Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway', 'publication_year': 2012, 'publication_date': '2012-03-01', 'ids': {'openalex': 'https://openalex.org/W2044911975', 'doi': 'https://doi.org/10.1016/j.devcel.2012.01.003', 'mag': '2044911975', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22421047', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3319042'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.devcel.2012.01.003', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S83804233', 'display_name': 'Developmental Cell', 'issn_l': '1534-5807', 'issn': ['1534-5807', '1878-1551'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://doi.org/10.1016/j.devcel.2012.01.003', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5025926869', 'display_name': 'Cong Xu', 'orcid': 'https://orcid.org/0000-0003-3689-5945'}, 'institutions': [{'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}, {'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}, {'id': 'https://openalex.org/I4210157861', 'display_name': 'Harvard Stem Cell Institute', 'ror': 'https://ror.org/04kj1hn59', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I136199984', 'https://openalex.org/I4210157861']}, {'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Cong Xu', 'raw_affiliation_strings': ["Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", "Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA"], 'affiliations': [{'raw_affiliation_string': "Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", 'institution_ids': ['https://openalex.org/I136199984', 'https://openalex.org/I4210117453', 'https://openalex.org/I4210157861']}, {'raw_affiliation_string': "Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", 'institution_ids': ['https://openalex.org/I4210157861', 'https://openalex.org/I136199984', 'https://openalex.org/I1344073410', 'https://openalex.org/I4210117453']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003953173', 'display_name': 'Zi Peng Fan', 'orcid': 'https://orcid.org/0009-0004-0094-6514'}, 'institutions': [{'id': 'https://openalex.org/I4210157710', 'display_name': 'Whitehead Institute for Biomedical Research', 'ror': 'https://ror.org/04vqm6w82', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210157710', 'https://openalex.org/I63966007']}, {'id': 'https://openalex.org/I63966007', 'display_name': 'Massachusetts Institute of Technology', 'ror': 'https://ror.org/042nb2s44', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I63966007']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Zi\xa0Peng Fan', 'raw_affiliation_strings': ['Whitehead Institute and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142 USA'], 'affiliations': [{'raw_affiliation_string': 'Whitehead Institute and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142 USA', 'institution_ids': ['https://openalex.org/I4210157710', 'https://openalex.org/I63966007']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077931913', 'display_name': 'Patrick Müller', 'orcid': 'https://orcid.org/0000-0002-0702-6209'}, 'institutions': [{'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Patrick Müller', 'raw_affiliation_strings': ['Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA', 'institution_ids': ['https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053772271', 'display_name': 'Rachel Fogley', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210157861', 'display_name': 'Harvard Stem Cell Institute', 'ror': 'https://ror.org/04kj1hn59', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I136199984', 'https://openalex.org/I4210157861']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}, {'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}, {'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Rachel Fogley', 'raw_affiliation_strings': ["Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA"], 'affiliations': [{'raw_affiliation_string': "Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", 'institution_ids': ['https://openalex.org/I4210157861', 'https://openalex.org/I136199984', 'https://openalex.org/I1344073410', 'https://openalex.org/I4210117453']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081789772', 'display_name': 'Anthony DiBiase', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210157861', 'display_name': 'Harvard Stem Cell Institute', 'ror': 'https://ror.org/04kj1hn59', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I136199984', 'https://openalex.org/I4210157861']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}, {'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}, {'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Anthony DiBiase', 'raw_affiliation_strings': ["Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", "Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA"], 'affiliations': [{'raw_affiliation_string': "Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", 'institution_ids': ['https://openalex.org/I4210157861', 'https://openalex.org/I136199984', 'https://openalex.org/I4210117453']}, {'raw_affiliation_string': "Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", 'institution_ids': ['https://openalex.org/I4210157861', 'https://openalex.org/I136199984', 'https://openalex.org/I1344073410', 'https://openalex.org/I4210117453']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016729487', 'display_name': 'Eirini Trompouki', 'orcid': 'https://orcid.org/0000-0002-7242-8810'}, 'institutions': [{'id': 'https://openalex.org/I4210157861', 'display_name': 'Harvard Stem Cell Institute', 'ror': 'https://ror.org/04kj1hn59', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I136199984', 'https://openalex.org/I4210157861']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}, {'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}, {'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Eirini Trompouki', 'raw_affiliation_strings': ["Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", "Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA"], 'affiliations': [{'raw_affiliation_string': "Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", 'institution_ids': ['https://openalex.org/I4210157861', 'https://openalex.org/I136199984', 'https://openalex.org/I1344073410', 'https://openalex.org/I4210117453']}, {'raw_affiliation_string': "Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", 'institution_ids': ['https://openalex.org/I4210157861', 'https://openalex.org/I136199984', 'https://openalex.org/I4210117453']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002611376', 'display_name': 'Juli Unternaehrer', 'orcid': 'https://orcid.org/0000-0001-5864-4704'}, 'institutions': [{'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}, {'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}, {'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}, {'id': 'https://openalex.org/I4210157861', 'display_name': 'Harvard Stem Cell Institute', 'ror': 'https://ror.org/04kj1hn59', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I136199984', 'https://openalex.org/I4210157861']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Juli Unternaehrer', 'raw_affiliation_strings': ["Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", "Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA"], 'affiliations': [{'raw_affiliation_string': "Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", 'institution_ids': ['https://openalex.org/I136199984', 'https://openalex.org/I1344073410', 'https://openalex.org/I4210117453', 'https://openalex.org/I4210157861']}, {'raw_affiliation_string': "Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", 'institution_ids': ['https://openalex.org/I4210157861', 'https://openalex.org/I136199984', 'https://openalex.org/I4210117453']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059536685', 'display_name': 'Fengzhu Xiong', 'orcid': 'https://orcid.org/0000-0002-6153-0254'}, 'institutions': [{'id': 'https://openalex.org/I4210155419', 'display_name': 'Center for Systems Biology', 'ror': 'https://ror.org/05r3dyn47', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I136199984', 'https://openalex.org/I4210087915', 'https://openalex.org/I4210155419', 'https://openalex.org/I48633490']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Fengzhu Xiong', 'raw_affiliation_strings': ['Department of Systems Biology, Harvard Medical School, Boston, MA 02115 USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Systems Biology, Harvard Medical School, Boston, MA 02115 USA', 'institution_ids': ['https://openalex.org/I4210155419', 'https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023839901', 'display_name': 'Ingrid Torregroza', 'orcid': 'https://orcid.org/0000-0002-5368-0834'}, 'institutions': [{'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ingrid Torregroza', 'raw_affiliation_strings': ['Department of Surgery, Weill Cornell Medical College of Cornell University, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, Weill Cornell Medical College of Cornell University, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I205783295']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003411069', 'display_name': 'Todd Evans', 'orcid': 'https://orcid.org/0000-0002-7148-9849'}, 'institutions': [{'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Todd Evans', 'raw_affiliation_strings': ['Department of Surgery, Weill Cornell Medical College of Cornell University, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Surgery, Weill Cornell Medical College of Cornell University, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I205783295']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029573236', 'display_name': 'Sean G. Megason', 'orcid': 'https://orcid.org/0000-0002-9330-2934'}, 'institutions': [{'id': 'https://openalex.org/I4210155419', 'display_name': 'Center for Systems Biology', 'ror': 'https://ror.org/05r3dyn47', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I136199984', 'https://openalex.org/I4210087915', 'https://openalex.org/I4210155419', 'https://openalex.org/I48633490']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sean\xa0G. Megason', 'raw_affiliation_strings': ['Department of Systems Biology, Harvard Medical School, Boston, MA 02115 USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Systems Biology, Harvard Medical School, Boston, MA 02115 USA', 'institution_ids': ['https://openalex.org/I4210155419', 'https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059348374', 'display_name': 'George Q. Daley', 'orcid': 'https://orcid.org/0000-0002-6346-5919'}, 'institutions': [{'id': 'https://openalex.org/I4210157861', 'display_name': 'Harvard Stem Cell Institute', 'ror': 'https://ror.org/04kj1hn59', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I136199984', 'https://openalex.org/I4210157861']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}, {'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}, {'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'George\xa0Q. Daley', 'raw_affiliation_strings': ["Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", "Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA"], 'affiliations': [{'raw_affiliation_string': "Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", 'institution_ids': ['https://openalex.org/I4210157861', 'https://openalex.org/I136199984', 'https://openalex.org/I4210117453']}, {'raw_affiliation_string': "Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", 'institution_ids': ['https://openalex.org/I4210157861', 'https://openalex.org/I136199984', 'https://openalex.org/I1344073410', 'https://openalex.org/I4210117453']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066848145', 'display_name': 'Alexander F. Schier', 'orcid': 'https://orcid.org/0000-0001-7645-5325'}, 'institutions': [{'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Alexander\xa0F. Schier', 'raw_affiliation_strings': ['Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA', 'institution_ids': ['https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102816742', 'display_name': 'Richard A. Young', 'orcid': 'https://orcid.org/0000-0001-5791-1604'}, 'institutions': [{'id': 'https://openalex.org/I4210157710', 'display_name': 'Whitehead Institute for Biomedical Research', 'ror': 'https://ror.org/04vqm6w82', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210157710', 'https://openalex.org/I63966007']}, {'id': 'https://openalex.org/I63966007', 'display_name': 'Massachusetts Institute of Technology', 'ror': 'https://ror.org/042nb2s44', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I63966007']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Richard\xa0A. Young', 'raw_affiliation_strings': ['Whitehead Institute and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142 USA'], 'affiliations': [{'raw_affiliation_string': 'Whitehead Institute and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142 USA', 'institution_ids': ['https://openalex.org/I4210157710', 'https://openalex.org/I63966007']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5086372369', 'display_name': 'Leonard I. Zon', 'orcid': 'https://orcid.org/0000-0003-0860-926X'}, 'institutions': [{'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}, {'id': 'https://openalex.org/I4210157861', 'display_name': 'Harvard Stem Cell Institute', 'ror': 'https://ror.org/04kj1hn59', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I136199984', 'https://openalex.org/I4210157861']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}, {'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Leonard\xa0I. Zon', 'raw_affiliation_strings': ["Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", "Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA"], 'affiliations': [{'raw_affiliation_string': "Division of Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", 'institution_ids': ['https://openalex.org/I4210117453', 'https://openalex.org/I4210157861', 'https://openalex.org/I136199984']}, {'raw_affiliation_string': "Howard Hughes Medical Institute, Children's Hospital Boston and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA", 'institution_ids': ['https://openalex.org/I4210157861', 'https://openalex.org/I136199984', 'https://openalex.org/I1344073410', 'https://openalex.org/I4210117453']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 8, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 9080, 'currency': 'USD', 'value_usd': 9080, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.697, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 103, 'citation_normalized_percentile': {'value': 0.999985, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '22', 'issue': '3', 'first_page': '625', 'last_page': '638'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10505', 'display_name': 'Pluripotent Stem Cells Research', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10505', 'display_name': 'Pluripotent Stem Cells Research', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11677', 'display_name': 'Congenital heart defects research', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10268', 'display_name': 'Developmental Biology and Gene Regulation', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/homeobox-protein-nanog', 'display_name': 'Homeobox protein NANOG', 'score': 0.959328}, {'id': 'https://openalex.org/keywords/nanog-homeobox-protein', 'display_name': 'Nanog Homeobox Protein', 'score': 0.75202036}, {'id': 'https://openalex.org/keywords/nodal-signaling', 'display_name': 'Nodal signaling', 'score': 0.54897034}, {'id': 'https://openalex.org/keywords/rex1', 'display_name': 'Rex1', 'score': 0.5236306}], 'concepts': [{'id': 'https://openalex.org/C207701140', 'wikidata': 'https://www.wikidata.org/wiki/Q420522', 'display_name': 'Homeobox protein NANOG', 'level': 5, 'score': 0.959328}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8742563}, {'id': 'https://openalex.org/C2777164004', 'wikidata': 'https://www.wikidata.org/wiki/Q331858', 'display_name': 'Endoderm', 'level': 4, 'score': 0.82255757}, {'id': 'https://openalex.org/C2908926650', 'wikidata': 'https://www.wikidata.org/wiki/Q420522', 'display_name': 'Nanog Homeobox Protein', 'level': 5, 'score': 0.75202036}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.55588377}, {'id': 'https://openalex.org/C205583638', 'wikidata': 'https://www.wikidata.org/wiki/Q7046607', 'display_name': 'Nodal signaling', 'level': 5, 'score': 0.54897034}, {'id': 'https://openalex.org/C207168726', 'wikidata': 'https://www.wikidata.org/wiki/Q18050439', 'display_name': 'Rex1', 'level': 5, 'score': 0.5236306}, {'id': 'https://openalex.org/C83330619', 'wikidata': 'https://www.wikidata.org/wiki/Q21124872', 'display_name': 'NODAL', 'level': 2, 'score': 0.50445783}, {'id': 'https://openalex.org/C121587040', 'wikidata': 'https://www.wikidata.org/wiki/Q898769', 'display_name': 'Homeobox', 'level': 4, 'score': 0.4991374}, {'id': 'https://openalex.org/C2776878037', 'wikidata': 'https://www.wikidata.org/wiki/Q169444', 'display_name': 'Zebrafish', 'level': 3, 'score': 0.4832919}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.41347855}, {'id': 'https://openalex.org/C145103041', 'wikidata': 'https://www.wikidata.org/wiki/Q1151519', 'display_name': 'Embryonic stem cell', 'level': 3, 'score': 0.3748812}, {'id': 'https://openalex.org/C2777933648', 'wikidata': 'https://www.wikidata.org/wiki/Q21114866', 'display_name': 'SOX2', 'level': 4, 'score': 0.34097707}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.31689733}, {'id': 'https://openalex.org/C129536746', 'wikidata': 'https://www.wikidata.org/wiki/Q1141026', 'display_name': 'Gastrulation', 'level': 4, 'score': 0.31312168}, {'id': 'https://openalex.org/C196843134', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryo', 'level': 2, 'score': 0.2759689}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.21228945}, {'id': 'https://openalex.org/C87073359', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryogenesis', 'level': 3, 'score': 0.19474173}, {'id': 'https://openalex.org/C107459253', 'wikidata': 'https://www.wikidata.org/wiki/Q674925', 'display_name': 'Induced pluripotent stem cell', 'level': 4, 'score': 0.18438068}], 'mesh': [{'descriptor_ui': 'D004707', 'descriptor_name': 'Endoderm', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D018398', 'descriptor_name': 'Homeodomain Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D047908', 'descriptor_name': 'Intracellular Signaling Peptides and Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D055456', 'descriptor_name': 'Nodal Signaling Ligands', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015027', 'descriptor_name': 'Zebrafish', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': True}, {'descriptor_ui': 'D029961', 'descriptor_name': 'Zebrafish Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004625', 'descriptor_name': 'Embryo, Nonmammalian', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004625', 'descriptor_name': 'Embryo, Nonmammalian', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004707', 'descriptor_name': 'Endoderm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018507', 'descriptor_name': 'Gene Expression Regulation, Developmental', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018398', 'descriptor_name': 'Homeodomain Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D018398', 'descriptor_name': 'Homeodomain Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047908', 'descriptor_name': 'Intracellular Signaling Peptides and Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000071317', 'descriptor_name': 'Nanog Homeobox Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055456', 'descriptor_name': 'Nodal Signaling Ligands', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015027', 'descriptor_name': 'Zebrafish', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015027', 'descriptor_name': 'Zebrafish', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015027', 'descriptor_name': 'Zebrafish', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D029961', 'descriptor_name': 'Zebrafish Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D029961', 'descriptor_name': 'Zebrafish Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.devcel.2012.01.003', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S83804233', 'display_name': 'Developmental Cell', 'issn_l': '1534-5807', 'issn': ['1534-5807', '1878-1551'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3319042', 'pdf_url': 'https://europepmc.org/articles/pmc3319042?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319042', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22421047', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.devcel.2012.01.003', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S83804233', 'display_name': 'Developmental Cell', 'issn_l': '1534-5807', 'issn': ['1534-5807', '1878-1551'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320332161', 'funder_display_name': 'National Institutes of Health', 'award_id': '5R01HL048801-18'}, {'funder': 'https://openalex.org/F4320332161', 'funder_display_name': 'National Institutes of Health', 'award_id': '5U01HL10001-02'}, {'funder': 'https://openalex.org/F4320332161', 'funder_display_name': 'National Institutes of Health', 'award_id': 'R01 HG002668'}, {'funder': 'https://openalex.org/F4320332161', 'funder_display_name': 'National Institutes of Health', 'award_id': 'HL056182'}], 'datasets': [], 'versions': [], 'referenced_works_count': 59, 'referenced_works': ['https://openalex.org/W1489916230', 'https://openalex.org/W1528309942', 'https://openalex.org/W1545772717', 'https://openalex.org/W158860518', 'https://openalex.org/W1803122644', 'https://openalex.org/W1824369405', 'https://openalex.org/W1920707660', 'https://openalex.org/W1968403914', 'https://openalex.org/W1971987459', 'https://openalex.org/W1976009549', 'https://openalex.org/W1981088384', 'https://openalex.org/W1985843365', 'https://openalex.org/W1988294855', 'https://openalex.org/W1989360008', 'https://openalex.org/W1990620111', 'https://openalex.org/W2004283021', 'https://openalex.org/W2010275561', 'https://openalex.org/W2011373586', 'https://openalex.org/W2015396326', 'https://openalex.org/W2017065102', 'https://openalex.org/W2021232061', 'https://openalex.org/W2022959322', 'https://openalex.org/W2024819483', 'https://openalex.org/W2026059202', 'https://openalex.org/W2026960397', 'https://openalex.org/W2030362521', 'https://openalex.org/W2039124939', 'https://openalex.org/W2045628618', 'https://openalex.org/W2046217837', 'https://openalex.org/W2047522987', 'https://openalex.org/W2060772796', 'https://openalex.org/W2072650825', 'https://openalex.org/W2074324848', 'https://openalex.org/W2079331738', 'https://openalex.org/W2080498142', 'https://openalex.org/W2082955515', 'https://openalex.org/W2092441894', 'https://openalex.org/W2093262939', 'https://openalex.org/W2098717020', 'https://openalex.org/W2107575419', 'https://openalex.org/W2110015307', 'https://openalex.org/W2110737932', 'https://openalex.org/W2126851387', 'https://openalex.org/W2129502556', 'https://openalex.org/W2130840634', 'https://openalex.org/W2133045719', 'https://openalex.org/W2142330433', 'https://openalex.org/W2146927398', 'https://openalex.org/W2150163104', 'https://openalex.org/W2151870437', 'https://openalex.org/W2157193608', 'https://openalex.org/W2161533644', 'https://openalex.org/W2161841253', 'https://openalex.org/W2164701483', 'https://openalex.org/W2166658859', 'https://openalex.org/W2166697185', 'https://openalex.org/W2167997874', 'https://openalex.org/W4232117151', 'https://openalex.org/W4232123484'], 'related_works': ['https://openalex.org/W3196835192', 'https://openalex.org/W2373796651', 'https://openalex.org/W2148099781', 'https://openalex.org/W2123806948', 'https://openalex.org/W2106840146', 'https://openalex.org/W2077661681', 'https://openalex.org/W2063334316', 'https://openalex.org/W2044911975', 'https://openalex.org/W1995050756', 'https://openalex.org/W1976337831'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2044911975', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 11}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 8}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 11}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 8}, {'year': 2013, 'cited_by_count': 10}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-18T11:04:55.981255', 'created_date': '2016-06-24'}