Title: Early Experiences in the Treatment of Falciparum Malaria From Southeast Asia
Abstract:Four hundred and twenty-six patients had 859 episodes of malaria due to<i>Plasmodium falciparum</i>in late 1965. An analysis of the results of therapy reveals the following data: chloroquine was succe...Four hundred and twenty-six patients had 859 episodes of malaria due to<i>Plasmodium falciparum</i>in late 1965. An analysis of the results of therapy reveals the following data: chloroquine was successful as treatment in 11% of the cases, quinine in 50%, chloroquine and quinine in 35%, pyrimethamine in 91%, quinine and pyrimethamine in 95%, and all three drugs combined in 80% Quinine alone was more effective, when used for 13 days or longer, than when used for 12 days or less. Chloroquine had a dose-related inhibitory effect on the success rate when combined with quinine. The best combination used was quinine and pyrimethamine.Read More
Publication Year: 1968
Publication Date: 1968-07-15
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 16
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot