Title: SODIUM AMYTAL AND OTHER DERIVATIVES OF BARBITURIC ACID
Abstract:APPRoxIiMATELY tWo years lhave elapsed sinice the fiirst studies were made oni the clinical use of sodium iso-anmylethyl-barbituric acid (sodium amytal ).In a preliminary report' certain clinical obse...APPRoxIiMATELY tWo years lhave elapsed sinice the fiirst studies were made oni the clinical use of sodium iso-anmylethyl-barbituric acid (sodium amytal ).In a preliminary report' certain clinical observationis were recorded, and attention was called to the need of further pharmacological and clinical work before definite conclusionis could be drawni as to the safety, contrainidications, and limitations of this compound.Since that time v-arious experimental and clinical observationis have been made by different in- vestigators, so that the status of this drug is now moro clearly defined.Tle puripose of this paper is to review briefly the data relating to sodiumn ansytal and similar compoun1ds.CHARACTERISTICS COMYON TO DERIVATIVES OF BARBITURIC ACID.All derivatives of barbituric acid hav-e certain character- istics in common which have long been recognized.1.They are primarily hypnotics; only occasionally will amiounts ordinarily producing hypnosis produce analgesiaRead More