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'(P692S': [86], 'Y635C)': [88], 'severely': [89], 'reduced': [90], 'extent': [92], 'To': [95], 'further': [96], 'demonstrate': [97, 235], 'specificity': [99], 'labeling,': [101], 'we': [102], 'show': [103], 'that': [104, 110, 165, 176, 189, 217, 236], 'NPC2,': [105], 'endosomal/lysosomal': [108], 'binds': [111], 'high': [115], 'affinity,': [116], 'labeled,': [118], 'whereas': [119], 'mutant': [120], 'NPC2': [121, 250], 'proteins': [122], 'inactive': [123], 'binding': [125, 197, 240, 246], 'are': [127], 'not.': [128], 'Vamp7,': [129], 'an': [130, 137, 167], 'abundant': [131], 'endosomal': [133, 179], 'membrane': [134], 'without': [136], 'SSD': [138, 255], 'one': [141], 'transmembrane': [142], 'domain,': [143], 'cannot': [144], 'be': [145], 'labeled.': [146], 'Binding': [147], 'between': [148, 241], 'H]AC': [151, 212], 'does': [154, 247], 'require': [156, 249], 'NPC2.': [157], 'Treating': [158], 'either': [161], 'U-18666A,': [162], 'compound': [164, 175], 'creates': [166], 'NPC-like': [168], 'phenotype,': [169], 'or': [170, 230], 'bafilomycin': [172], 'A1,': [173], 'raises': [177], 'pH,': [180], 'has': [181], 'no': [182], 'effect': [183], 'on': [184], 'NPC1-YFP,': [187], 'suggesting': [188], 'both': [190], 'drugs': [191], 'affect': [192], 'processes': [193], 'than': [195, 226], 'also': [201], 'developed': [202], 'procedure': [204], 'label': [206], 'NPC1-YFP': [208], 'vitro': [214], 'showed': [216], 'more': [220], 'effective': [221], 'protection': [223], 'against': [224], 'its': [227], 'analogs': [228], 'epicholesterol': [229], '5-α-cholestan.': [231], 'Overall,': [232], 'results': [234], 'there': [237], 'direct': [239], 'azocholestanol;': [244], 'requires': [252], 'functional': [254], 'within': [256], 'NPC1.': [257]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2044272444', 'counts_by_year': [{'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 6}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 12}, {'year': 2019, 'cited_by_count': 12}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 9}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 10}], 'updated_date': '2024-12-18T17:08:27.116852', 'created_date': '2016-06-24'}