Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2044099387', 'doi': 'https://doi.org/10.1016/0140-6736(91)91961-s', 'title': 'Effect of outer membrane vesicle vaccine against group B meningococcal disease in Norway', 'display_name': 'Effect of outer membrane vesicle vaccine against group B meningococcal disease in Norway', 'publication_year': 1991, 'publication_date': '1991-11-01', 'ids': {'openalex': 'https://openalex.org/W2044099387', 'doi': 'https://doi.org/10.1016/0140-6736(91)91961-s', 'mag': '2044099387', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/1682541'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0140-6736(91)91961-s', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S49861241', 'display_name': 'The Lancet', 'issn_l': '0140-6736', 'issn': ['0140-6736', '1474-547X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5091004361', 'display_name': 'Patrick A. D. Grimont', 'orcid': 'https://orcid.org/0000-0002-6264-136X'}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'G Bjune', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029380698', 'display_name': 'E. Arne Høiby', 'orcid': None}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'E.A Høiby', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050269651', 'display_name': 'Jon Ketil Grønnesby', 'orcid': None}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'J.K Grønnesby', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044523225', 'display_name': 'Øyvind Arnesen', 'orcid': None}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'Ø Arnesen', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031000363', 'display_name': 'J. HOLST Fredriksen', 'orcid': None}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'J.H Fredriksen', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045678744', 'display_name': 'A-K Lindbak', 'orcid': None}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'A-K Lindbak', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084886807', 'display_name': 'Hanne Nøkleby', 'orcid': 'https://orcid.org/0000-0003-2332-2443'}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'H Nøkleby', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068583234', 'display_name': 'Einar Rosenqvist', 'orcid': None}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'E Rosenqvist', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084883364', 'display_name': 'L.K Solberg', 'orcid': None}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'L.K Solberg', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086309649', 'display_name': 'O Closs', 'orcid': None}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'O Closs', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084103512', 'display_name': 'L O Frøholm', 'orcid': None}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'L.O Frøholm', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033459008', 'display_name': 'A Lystad', 'orcid': None}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'A Lystad', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031302904', 'display_name': 'Leiv S. Bakketeig', 'orcid': None}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'L.S Bakketeig', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041759195', 'display_name': 'B Hareide', 'orcid': None}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'B Hareide', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053091389', 'display_name': 'A Halstensen', 'orcid': None}, 'institutions': [], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'A Halstensen', 'raw_affiliation_strings': ['Department of Medicine, Haukeland Hospital, N-5021 Bergen, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Haukeland Hospital, N-5021 Bergen, Belgium', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021089951', 'display_name': 'Eirik Holten', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800192669', 'display_name': 'Akershus University Hospital', 'ror': 'https://ror.org/0331wat71', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800192669']}], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'E Holten', 'raw_affiliation_strings': ['Department of Microbiology, Akershus Central Hospital, N-1474 Nordbyhagen, Norway.'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, Akershus Central Hospital, N-1474 Nordbyhagen, Norway.', 'institution_ids': ['https://openalex.org/I2800192669']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5021458318', 'display_name': 'Jan Eng', 'orcid': None}, 'institutions': [], 'countries': ['NO'], 'is_corresponding': False, 'raw_author_name': 'J Eng', 'raw_affiliation_strings': ['National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'National Institute of Public Health, Geitmyrsveien 75, N-0462 Oslo, Norway', 'institution_ids': []}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 6830, 'currency': 'USD', 'value_usd': 6830, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 9.424, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 688, 'citation_normalized_percentile': {'value': 0.988342, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '338', 'issue': '8775', 'first_page': '1093', 'last_page': '1096'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10873', 'display_name': 'Epidemiology and Pathogenesis of Bacterial Meningitis', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2404', 'display_name': 'Microbiology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10873', 'display_name': 'Epidemiology and Pathogenesis of Bacterial Meningitis', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2404', 'display_name': 'Microbiology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10654', 'display_name': 'Management and Epidemiology of Pneumonia', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11243', 'display_name': 'Epidemiology and Pathogenesis of Respiratory Viral Infections', 'score': 0.9938, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/meningococcal-vaccine', 'display_name': 'Meningococcal vaccine', 'score': 0.68300915}, {'id': 'https://openalex.org/keywords/case-fatality-rate', 'display_name': 'Case fatality rate', 'score': 0.60933006}, {'id': 'https://openalex.org/keywords/group-b', 'display_name': 'Group B', 'score': 0.5221211}, {'id': 'https://openalex.org/keywords/outer-membrane-vesicles', 'display_name': 'Outer Membrane Vesicles', 'score': 0.518629}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8106959}, {'id': 'https://openalex.org/C2776645655', 'wikidata': 'https://www.wikidata.org/wiki/Q890785', 'display_name': 'Meningococcal disease', 'level': 4, 'score': 0.7722483}, {'id': 'https://openalex.org/C2780454893', 'wikidata': 'https://www.wikidata.org/wiki/Q6817090', 'display_name': 'Meningococcal vaccine', 'level': 4, 'score': 0.68300915}, {'id': 'https://openalex.org/C22070199', 'wikidata': 'https://www.wikidata.org/wiki/Q192995', 'display_name': 'Vaccination', 'level': 2, 'score': 0.6152493}, {'id': 'https://openalex.org/C187316915', 'wikidata': 'https://www.wikidata.org/wiki/Q92307203', 'display_name': 'Case fatality rate', 'level': 3, 'score': 0.60933006}, {'id': 'https://openalex.org/C2778458888', 'wikidata': 'https://www.wikidata.org/wiki/Q154625', 'display_name': 'Neisseria meningitidis', 'level': 3, 'score': 0.6092324}, {'id': 'https://openalex.org/C61511704', 'wikidata': 'https://www.wikidata.org/wiki/Q1671857', 'display_name': 'Incidence (geometry)', 'level': 2, 'score': 0.6008491}, {'id': 'https://openalex.org/C27081682', 'wikidata': 'https://www.wikidata.org/wiki/Q269829', 'display_name': 'Placebo', 'level': 3, 'score': 0.5697477}, {'id': 'https://openalex.org/C2781026528', 'wikidata': 'https://www.wikidata.org/wiki/Q48143', 'display_name': 'Meningitis', 'level': 2, 'score': 0.53767276}, {'id': 'https://openalex.org/C2777785397', 'wikidata': 'https://www.wikidata.org/wiki/Q492194', 'display_name': 'Group B', 'level': 2, 'score': 0.5221211}, {'id': 'https://openalex.org/C187212893', 'wikidata': 'https://www.wikidata.org/wiki/Q123028', 'display_name': 'Pediatrics', 'level': 1, 'score': 0.422611}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.34873742}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.31824964}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.28473565}, {'id': 'https://openalex.org/C107130276', 'wikidata': 'https://www.wikidata.org/wiki/Q133805', 'display_name': 'Epidemiology', 'level': 2, 'score': 0.27615458}, {'id': 'https://openalex.org/C2780801004', 'wikidata': 'https://www.wikidata.org/wiki/Q1415366', 'display_name': 'Immunization', 'level': 3, 'score': 0.21106106}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.07107976}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C120665830', 'wikidata': 'https://www.wikidata.org/wiki/Q14620', 'display_name': 'Optics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000942', 'descriptor_name': 'Antigens, Bacterial', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D001425', 'descriptor_name': 'Bacterial Outer Membrane Proteins', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D001428', 'descriptor_name': 'Bacterial Vaccines', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D004196', 'descriptor_name': 'Disease Outbreaks', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D008585', 'descriptor_name': 'Meningitis, Meningococcal', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D009345', 'descriptor_name': 'Neisseria meningitidis', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D011135', 'descriptor_name': 'Polysaccharides, Bacterial', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D014611', 'descriptor_name': 'Vaccination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000942', 'descriptor_name': 'Antigens, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016667', 'descriptor_name': 'Bacterial Capsules', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001425', 'descriptor_name': 'Bacterial Outer Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001428', 'descriptor_name': 'Bacterial Vaccines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002675', 'descriptor_name': 'Child, Preschool', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004196', 'descriptor_name': 'Disease Outbreaks', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004311', 'descriptor_name': 'Double-Blind Method', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005069', 'descriptor_name': 'Evaluation Studies as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005500', 'descriptor_name': 'Follow-Up Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007115', 'descriptor_name': 'Immunization Schedule', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007223', 'descriptor_name': 'Infant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008585', 'descriptor_name': 'Meningitis, Meningococcal', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D008585', 'descriptor_name': 'Meningitis, Meningococcal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D022401', 'descriptor_name': 'Meningococcal Vaccines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009345', 'descriptor_name': 'Neisseria meningitidis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009664', 'descriptor_name': 'Norway', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D009664', 'descriptor_name': 'Norway', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011135', 'descriptor_name': 'Polysaccharides, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0140-6736(91)91961-s', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S49861241', 'display_name': 'The Lancet', 'issn_l': '0140-6736', 'issn': ['0140-6736', '1474-547X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/1682541', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.81, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 15, 'referenced_works': ['https://openalex.org/W1989542439', 'https://openalex.org/W1991844560', 'https://openalex.org/W2011048047', 'https://openalex.org/W2080113534', 'https://openalex.org/W2136883754', 'https://openalex.org/W2150290224', 'https://openalex.org/W2178685600', 'https://openalex.org/W2398682099', 'https://openalex.org/W2437851021', 'https://openalex.org/W2797482815', 'https://openalex.org/W2889459752', 'https://openalex.org/W2963397397', 'https://openalex.org/W2963829899', 'https://openalex.org/W2963874641', 'https://openalex.org/W3015688538'], 'related_works': ['https://openalex.org/W4387115080', 'https://openalex.org/W4246281681', 'https://openalex.org/W4234828240', 'https://openalex.org/W4230979920', 'https://openalex.org/W2408300477', 'https://openalex.org/W2405842676', 'https://openalex.org/W2258349998', 'https://openalex.org/W2163631167', 'https://openalex.org/W2070553347', 'https://openalex.org/W2048853144'], 'abstract_inverted_index': {'<h2>Abstract</h2>': [0], 'For': [1], 'more': [2], 'than': [3], '15': [4], 'years,': [5], 'Norway': [6], 'has': [7, 30], 'had': [8, 44], 'the': [9, 56, 89, 134, 162, 191, 200], 'highest': [10], 'incidence': [11], 'of': [12, 20, 109, 133, 178], 'meningococcal': [13, 198], 'disease': [14, 101, 148], 'in': [15, 52, 61, 73, 80, 114, 117, 156, 161], 'northern': [16], 'Europe,': [17], 'with': [18, 86, 99, 166, 171], '80%': [19], 'cases': [21, 108, 120, 136, 155], 'being': [22], 'due': [23, 149], 'to': [24, 48, 55, 77, 104, 127, 144, 150, 204], 'serogroup': [25], 'B': [26, 152, 197], 'meningococci.': [27, 153], 'The': [28, 175, 186], 'case-fatality': [29], 'remained': [31], 'high,': [32], 'at': [33], 'about': [34], '10%.': [35], 'In': [36], 'this': [37], 'study,': [38], 'an': [39, 50], 'outer': [40], 'membrane': [41], 'vaccine,': [42], 'which': [43], 'previously': [45], 'been': [46], 'shown': [47, 143], 'induce': [49], 'increase': [51], 'bactericidal': [53], 'antibodies': [54], 'parent': [57], 'strain,': [58], 'was': [59, 180, 202], 'assessed': [60], 'a': [62, 81, 128, 206], 'large-scale,': [63], 'randomised,': [64], 'double-blind': [65], 'trial.': [66], 'From': [67], 'October,': [68], '1988,': [69], '171': [70], '800': [71], 'students': [72, 116, 168, 172], 'secondary': [74], 'schools': [75, 158, 165], 'volunteered': [76], 'take': [78], 'part': [79, 160], 'double-blind,': [82], 'placebo-controlled,': [83], 'efficacy': [84], 'trial': [85, 163], 'school': [87], 'as': [88], 'randomisation': [90], 'unit.': [91], 'Hospitals': [92], 'and': [93, 123, 169], 'clinics': [94], 'that': [95], 'routinely': [96], 'receive': [97], 'patients': [98], 'infectious': [100], 'were': [102, 121, 142], 'asked': [103], 'report': [105], 'urgently': [106], 'all': [107], 'suspected': [110], 'meningitis': [111], 'and/or': [112], 'septicaemia': [113], '13-21-year-old': [115], 'Norway.': [118], 'These': [119], 'registered': [122], 'further': [124], 'investigated': [125, 137], 'according': [126], 'detailed': [129], 'protocol.': [130], '89': [131], 'out': [132], '221': [135], 'by': [138], 'June': [139], '3,': [140], '1991,': [141], 'be': [145], 'severe': [146], 'systemic': [147], 'group': [151, 196], '36': [154], '35': [157], 'took': [159], '(11': [164], 'vaccinated': [167], '24': [170], 'given': [173], 'placebo).': [174], 'calculated': [176], 'rate': [177], 'protection': [179, 194], 'thus': [181], '57·2%': [182], '(p=0·012,': [183], 'one-sided': [184], 'test).': [185], 'findings': [187], 'suggest': [188], 'that,': [189], 'although': [190], 'vaccine': [192], 'conferred': [193], 'against': [195], 'disease,': [199], 'effect': [201], 'insufficient': [203], 'justify': [205], 'public': [207], 'vaccination': [208], 'programme.': [209]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2044099387', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 15}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 9}, {'year': 2020, 'cited_by_count': 11}, {'year': 2019, 'cited_by_count': 15}, {'year': 2018, 'cited_by_count': 14}, {'year': 2017, 'cited_by_count': 17}, {'year': 2016, 'cited_by_count': 17}, {'year': 2015, 'cited_by_count': 22}, {'year': 2014, 'cited_by_count': 28}, {'year': 2013, 'cited_by_count': 23}, {'year': 2012, 'cited_by_count': 22}], 'updated_date': '2024-09-13T00:56:36.173795', 'created_date': '2016-06-24'}