Publication Information

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'evidence': [86], 'provide': [88, 188, 2692], 'effective': [89, 156], 'medical': [90, 691, 879, 902, 914], 'tailored': [94], 'local': [96, 147], 'systems': [99, 1054, 1092], 'resources.': [101], 'Working': [102], 'continued': [104], 'collaboration': [105], 'with': [106, 209, 296, 505, 584, 669, 680, 815, 978, 1323, 1365, 1393, 1465, 2092, 2261, 2314, 2359, 2410, 2441, 2585, 2625, 2726, 2805, 2808, 2925, 3044, 3295, 3319, 3351], 'leaders': [107], 'countries,': [113, 2176, 2292], 'sponsors': [115], 'World': [116, 165, 348, 462, 3335, 3362], 'Day': [118, 167, 464], '(first': [119], 'Tuesday': [120], 'May)': [122], 'which': [123, 750, 961, 1055, 1184, 1238, 1271, 1372, 1450, 1558, 1680, 1847, 2033, 2043, 2076, 2485, 2519, 2647, 2660, 2905, 2974, 2984, 3075, 3234], 'has': [124, 168, 559, 581, 729, 1185, 1451, 1485, 1577, 2073, 2116, 2126, 2221, 2338, 2735, 2763, 3087, 3145], 'been': [125, 169, 307, 386, 582, 730, 963, 1374, 1443, 1452, 1486, 1505, 1578, 1605, 2027, 2035, 2074, 2117, 2127, 2222, 2339, 2353, 2736, 2764, 2835, 3069, 3088, 3147], 'extremely': [126, 455, 2796], 'successful.': [127], 'A': [128, 196], 'vast': [129], 'number': [130, 299, 648, 719, 760, 1723, 1926, 2622, 2710, 2723, 3157], 'have': [133, 306, 385, 497, 684, 962, 1373, 1433, 1442, 1504, 1508, 1604, 2026, 2034, 2044, 2834, 3068], 'made': [134, 1819, 2737, 3211], 'commitment': [136], 'bring': [138], 'about': [140, 735, 861, 1496, 2392, 2418], 'their': [146, 1317], 'implement': [153, 1066, 1282], 'programs': [154, 1408], 'care.': [158, 692, 1244], 'Beginning': [159], '2003,': [161], 'theme': [163], '‘‘Global': [171], 'Burden': [172], 'Asthma.’’': [174], 'commissioned': [176], 'Professor': [177, 225, 276, 420], 'Richard': [178], 'Beasley,': [179], 'Wellington,': [180], 'New': [181], 'Zealand': [182], '(member,': [183], 'Dissemination': [185], 'Committee)': [186], 'data': [190, 210, 231, 267, 320, 339, 375, 381, 444, 1024, 1600, 1613, 1634, 1689, 2025, 2065, 2500, 2661, 2827, 2841, 2897, 2986, 2994, 3100, 3168, 3327], 'asthma.': [195, 498, 514, 532, 758, 853, 1030, 1046, 1167, 1198, 1279, 1466, 1783, 1809, 1879, 2190], 'summary': [197], 'report': [200, 289, 396, 428, 1582, 2193, 2614], 'provided': [202, 807, 840, 1162], 'publication;': [205], 'full': [207, 288], 'document': [208, 3150], 'sets': [211], '20': [213], 'different': [214, 1308, 1346, 1623, 2093, 2163, 2175, 2236, 3050, 3131], 'regions': [215, 305, 1188], 'worldwide': [216, 651, 728, 3313], 'may': [217, 662, 1056], 'be': [218, 398, 431, 454, 503, 642, 663, 716, 733, 806, 839, 1101, 1455, 1728, 1802, 1805, 2134, 2298, 2717, 3041], 'obtained': [219, 230, 504, 1607, 1631, 1704, 3329], 'website': [223], '(http://www.ginasthma.com).': [224], 'Beasley': [226, 277, 421], 'his': [228, 281, 423], 'colleagues': [229, 424], 'literature': [238], 'primarily': [239], 'published': [240, 1691, 2918, 3333], 'through': [241], 'International': [243, 1536], 'Study': [244, 1537], 'Allergies': [248, 1541], 'Childhood': [250, 1543], '(ISAAC)': [251, 1544], 'European': [254, 1547], 'Community': [255, 1548], 'Respiratory': [256, 1549], 'Health': [257, 1550, 3336, 3363], 'Survey': [258, 1551], '(ECHRS).': [259], 'Methodologies': [260], 'differ': [261], 'these': [263, 1569, 1626, 2703, 2862, 3167], 'studies,': [264, 2351], 'epidemiological': [266, 338, 374, 1857], 'are': [270, 521, 825, 833, 872, 970, 1301, 1898, 2688, 2795, 2865, 3316], 'very': [271], 'difficult': [272, 1064, 2150], 'collect,': [274], 'carefully': [278], 'describes': [279, 2080], 'segment': [282], '‘‘Methodological': [284], 'Issues.’’': [285], 'Nonetheless,': [286], 'provides': [290, 2102], 'wealth': [292, 696], 'information,': [294], 'along': [295], 'large': [298, 830, 1417, 1554, 1860], 'references.': [302], 'study': [304, 342, 1630, 1988, 2894], 'grouped': [308], 'according': [309], 'geographical,': [311], 'political,': [312], 'historical,': [313], 'racial': [315, 820], 'considerations': [316], 'official': [319], 'WHO,': [322], 'United': [324, 346], 'Nations': [325, 347], '(UN),': [326], 'other': [328, 597, 1012, 1324, 2776, 2793], 'sources,': [329], 'some': [332, 366, 380, 1187, 1922, 2041], 'extent,': [333], 'availability': [335, 1108, 1241], 'within': [340, 357, 705, 1480, 1903], 'region.': [343, 451], 'Using': [344], 'Population': [349, 351], 'Prospect': [350], 'Database': [352], '(http://esa.un.org/unpp)': [353], 'source': [356, 434], 'each': [358, 1595, 1917, 2628, 2637, 2714, 2961, 3072, 3164, 3349], 'region,': [359], 'countries': [361, 410, 706, 785, 1063, 1297, 1566, 1624, 1657, 1679, 2484, 2518, 2658, 2734, 2900, 3025], 'were': [362, 376, 1614, 1693, 1958, 2012, 2666, 2923, 2951, 2987, 2995, 3000, 3101, 3169, 3328], 'included,': [363], 'cases': [367], 'territories': [368, 384], 'dependencies': [370], 'if': [371, 1695, 2998], 'specific': [372, 1757, 2677], 'available.': [377, 3102], 'For': [378, 1568, 1678, 1784, 2657, 2960], 'simplicity': [379], 'small': [383], 'omitted': [387], 'or': [388, 690, 777, 832, 1120, 1666, 1686, 1713, 1773, 1844, 1851, 2562, 2819, 2853, 2881, 3155], 'lumped': [389], 'larger': [392], 'sub-regional': [393], 'unit.': [394], 'will': [397, 430, 453], 'updated': [399], 'new': [401], 'information': [402, 436, 1146, 1825, 2011], 'becomes': [403], 'following': [406], 'feedback': [407], 'individual': [409, 1795, 2584], 'regions.': [412], 'Executive': [415], 'Committee': [416], 'indebted': [418], 'providing': [426], 'invaluable': [433], 'those': [438, 823, 1410, 1991, 2815], 'who': [439, 824], 'wish': [440], 'explore': [442], 'by': [450, 524, 593, 671, 2283, 2381, 2459, 2582, 2598, 2641, 2891, 2919], 'useful': [456], 'develop': [458], 'background': [459], 'materials': [460], 'activities': [465], '2004': [467], 'well': [469, 2178], 'into': [470, 534, 1349, 2037], 'future.': [472], 'one': [475, 1661, 3296, 3302], 'most': [478, 1457, 2104, 2970], 'common': [479, 562], 'chronic': [480, 2845, 2879], 'diseases': [481, 1044], 'world.': [484, 1229], 'around': [489, 568, 744, 2322], 'world': [495, 570, 678, 3340], 'currently': [496, 734], 'Considerably': [499], 'higher': [500, 1972], 'estimates': [501, 2107], 'can': [502, 2297, 3040], 'less': [506], 'conservative': [507, 2617], 'criteria': [508, 2332], 'diagnosis': [511, 1519, 1760, 1815, 2752], 'clinical': [513, 1808, 1812, 1845, 1878, 2347, 2363, 2673, 2700, 3097], 'international': [516, 1292, 1419, 1556, 2059, 3008, 3054], 'patterns': [517], 'prevalence': [520, 578, 754, 949, 1216, 1425, 1561, 1589, 1633, 1671, 1866, 1876, 1893, 1913, 1948, 1966, 2064, 2110, 2146, 2201, 2226, 2245, 2276, 2306, 2378, 2406, 2422, 2439, 2448, 2468, 2499, 2530, 2555, 2606, 2632, 2665, 2671, 2698, 3021, 3095, 3126], 'not': [522, 683, 1682, 1745, 1754, 1800, 1872, 2281, 2667, 2849, 2996, 3146, 3170], 'explained': [523, 2282, 2458], 'current': [526, 1490, 1591, 1742, 1868, 1895, 2278, 2295, 2319, 2329, 2336, 2397, 2425, 2450, 2471, 2533], 'knowledge': [527], 'causation': [530, 536, 1398], 'Research': [533, 1396], 'asthma,': [538, 951, 1218, 1400, 1854, 2086, 2558, 2843, 3098], 'efficacy': [541], 'primary': [543, 1401, 2138], 'secondary': [545, 1403], 'intervention': [546, 1404], 'strategies,': [547, 1405], 'represent': [548, 707, 2615, 3111], 'key': [549, 1342], 'priority': [550, 796, 953, 1006], 'areas': [551, 675], 'field': [554], 'research.': [557], 'become': [560, 616, 944], 'more': [561, 1659, 3032], 'both': [564, 897, 1429, 1514, 1523, 1534, 1885, 1951, 2002, 2488, 2521, 3236, 3256], 'children': [565, 1329, 1430, 1524, 1636, 1712, 1886, 2206, 2376, 2474, 2510], 'adults': [567, 1432, 2404, 2453], 'recent': [572, 2971], 'decades.': [573, 656], 'increase': [575, 586, 621, 645], 'associated': [583], 'atopic': [588], 'sensitization,': [589], 'paralleled': [592], 'similar': [594, 768, 2254, 2866], 'increases': [595, 609], 'allergic': [598], 'disorders': [599], 'such': [600, 845, 1015, 1734], 'eczema': [602], 'rhinitis.': [604], 'rate': [606, 1914, 2379, 2407, 2423, 2469, 2531, 2966, 3039, 3079], 'communities': [611], 'adopt': [612], 'western': [613], 'lifestyles': [614], 'urbanized.': [617], 'With': [618], 'projected': [620], 'proportion': [624, 2311, 3092], "world's": [627], 'population': [628, 1931, 2643, 2653, 3347], 'urban': [631, 1956, 1974], '45%': [633], '59%': [635], '2025,': [637], 'there': [638, 661, 926, 1335, 1764], 'likely': [640], 'marked': [644, 2572], 'asthmatics': [650, 2712], 'over': [652, 1834, 2038], 'next': [654], 'two': [655, 2969], 'additional': [665], '100': [666], 'persons': [668, 679, 975, 1390, 2624, 2725], '2025.': [672], 'do': [682], 'access': [685, 3353], 'basic': [687, 1116], 'medications': [689, 1112, 1117], 'Increasing': [693], 'economic': [695, 891, 1207, 1234], 'improving': [698], 'distribution': [700, 1128], 'resources': [702, 803, 1161], 'between': [703, 1620, 1901, 2090, 2111, 2433, 2495, 2600, 2733], 'important': [708, 1203, 1458], 'priorities': [709], 'enable': [711], 'better': [712], 'provided.': [717], 'disability-adjusted': [721], 'life': [722, 3198, 3219, 3227, 3239, 3276], 'years(DALYs)': [723], 'lost': [724, 763, 919, 3220, 3266, 3277, 3309], 'due': [725, 764, 875, 1007, 1224, 1277, 2153, 2569, 2872, 3160, 3310], '15': [736], 'per': [738], 'year.': [739], 'Worldwide,': [740], 'accounts': [742, 859], '1%': [745], 'DALYs': [748, 762, 3308], 'lost,': [749, 3228], 'reflects': [751], 'high': [753, 816], 'severity': [756, 1772, 2361], 'diabetes,': [772], 'cirrhosis': [773], 'liver,': [776], 'schizophrenia.': [778], 'sufficient': [788], 'magnitude': [789], 'warrant': [791], 'its': [792, 2114], 'recognition': [793, 2576, 3138], 'disorder': [797], 'strategies.': [801], 'Particular': [802], 'need': [804, 837, 1726], 'improve': [809], 'disadvantaged': [813], 'groups': [814, 821, 2523], 'morbidity,': [817, 1206], 'including': [818, 983, 992, 1045, 1166, 1266, 1275, 1409, 3119], 'certain': [819], 'poorly': [826], 'educated,': [827], 'live': [828], 'cities,': [831], 'poor.': [834], 'Resources': [835], 'also': [836, 1942, 3017], 'address': [842, 1232, 1262], 'preventable': [843], 'factors,': [844], 'air': [847, 996], 'pollution,': [848, 997], 'trigger': [850], 'exacerbations': [851], '1': [862], 'every': [864], '250': [865], 'deaths': [866, 871, 2774, 2788, 3159], 'Many': [868], 'preventable,': [873], 'being': [874, 2778, 2789, 3026], 'suboptimal': [877], 'long-term': [878], 'delay': [882], 'obtaining': [884], 'help': [885], 'during': [886], 'final': [888], 'attack.': [889], 'cost': [892, 909, 1130], 'considerable': [896, 2591], 'terms': [899, 1082, 1306, 3187], 'direct': [901], 'costs': [903, 915], '(such': [904, 916], 'hospital': [906], 'admissions': [907], 'pharmaceuticals)': [911], 'indirect': [913], 'time': [918, 1479], 'work': [921], 'premature': [923, 3279], 'death).': [924], 'Until': [925], 'greater': [929, 2360], 'understanding': [930], 'factors': [933, 1143, 1237, 1265, 3118], 'cause': [935, 1204], 'novel': [938], 'pharmacological': [942], 'measures': [943, 2000, 2366], 'reduce': [947, 966, 1288, 1377, 2054], 'ensure': [956, 1299], 'cost-effective': [958, 1369], 'approaches': [960, 1038, 1371], 'proven': [964, 1375], 'morbidity': [967, 1026, 1221, 1274, 1378], 'mortality': [969, 1028, 1210, 1223, 2731, 2741, 2755, 2826, 2840, 2863, 2870, 2877, 2908, 2928, 2942, 2965, 2985, 2993, 3012, 3058, 3078, 3124, 3153, 3280], 'possible': [977, 1392, 3148], 'Generic': [981], 'barriers': [982, 991, 1073, 1140], 'poverty,': [984], 'poor': [985, 988, 1125], 'education,': [986], 'infrastructure.': [989], 'Environmental': [990], 'indoor': [993, 1267], 'outdoor': [995, 1269], 'tobacco': [998, 1289], 'smoking,': [999], 'occupational': [1001], 'exposures.': [1002], 'Low': [1003], 'importance': [1010], 'respiratory': [1013, 1043, 1171, 1273, 1326, 1347, 1362], 'illnesses': [1014], 'tuberculosis': [1017], 'pneumonia': [1019], 'lack': [1022, 1032, 1144, 2156], 'symptom-based': [1034], 'rather': [1035, 1103, 2078], 'than': [1036, 1104, 1660, 1975, 2079, 2372], 'disease-based': [1037], 'Unsustainable': [1047], 'generalizations': [1048], 'across': [1049], 'cultures': [1050, 2094], 'make': [1057], 'guidelines': [1059, 1294, 1322, 1327, 1348], 'developed': [1060, 2075], 'high-income': [1062], 'low': [1068, 2241], 'middle-income': [1070, 1258], 'countries.': [1071, 1259, 1415, 2704], 'Inherent': [1072], 'organization': [1076], 'services': [1080], 'of:': [1083], 'geography': [1084], 'type': [1085, 3046], 'professional': [1087, 2187], 'responding': [1088], 'education': [1089], 'training': [1091], 'private': [1095], 'tendency': [1097], '‘‘acute’’': [1102], '‘‘routine.’’': [1105], 'limited': [1107], 'use': [1110, 1154, 1353, 1412, 1981, 2115, 2566], 'including:': [1113, 1141], 'omission': [1114], 'WHO': [1119, 2652, 2824, 2927, 2957, 3174, 3334, 3361], 'national': [1121, 1421, 2267, 2921], 'essential': [1122, 1248, 3355], 'drug': [1123, 1134], 'lists': [1124], 'supply': [1126], 'infrastructure': [1129], 'cultural': [1131, 1142], 'attitudes': [1132], 'towards': [1133], 'delivery': [1135], 'e.g.': [1137], 'inhalers': [1138], 'Patient': [1139], 'underuse': [1147], 'self-management': [1149], 'over-reliance': [1150], 'acute': [1152, 2852], 'alternative': [1156, 2373], 'unproven': [1157], 'therapies.': [1158], 'Inadequate': [1159], 'requirement': [1169, 1338], 'specialists': [1172], 'related': [1174], 'organizations': [1175], 'wide': [1180, 1889, 2273], 'variety': [1181], 'diseases,': [1183], 'resulted': [1189], 'failure': [1192], 'adequately': [1194], 'promote': [1195], 'Recognize': [1199], 'cost,': [1208], 'Measure': [1212], 'monitor': [1214], 'throughout': [1227], 'Identify': [1230, 1260], 'political': [1236], 'limit': [1239], 'Improve': [1245], 'accessibility': [1246], 'drugs': [1249, 3356], 'low-': [1256], 'environmental': [1264], 'pollution': [1270], 'affect': [1272], 'Promote': [1280, 1368], 'anti-tobacco': [1283], 'policies': [1286], 'consumption.': [1290], 'Adapt': [1291], 'developing': [1296, 1414], 'they': [1300, 2999], 'practical': [1302], 'realistic': [1304], 'systems.': [1311], 'This': [1312, 1527, 1907, 2014, 2269, 2331, 2705, 2887, 2936, 3247], 'includes': [1313], 'dissemination': [1314], 'strategies': [1315], 'implementation.': [1318], 'Integrate': [1319], 'global': [1325], 'adults.': [1331, 1526, 1714], 'respect,': [1334], 'merge': [1340], 'elements': [1343], 'algorithm': [1351], 'at': [1354, 1477, 2265, 2454], 'first': [1356, 1738], 'point': [1357], 'entry': [1359], "patient's": [1363], 'contact': [1364], 'services.': [1367], 'mortality,': [1380, 3189], 'thereby': [1381, 2087, 2720], 'ensuring': [1382], 'optimal': [1383], 'treatment': [1384, 1798, 2368, 2597], 'standardised': [1418, 1555, 1735, 1983, 2030, 3177], 'studies': [1422, 1557, 1692, 1858, 2024], 'utilized': [1434], 'written': [1435, 1706, 1985, 2031, 2068, 2401], 'questionnaires': [1436, 1441, 1707, 2032], 'symptoms.': [1439, 1492], 'These': [1440, 2837, 3326], 'symptom': [1447, 1459, 1632, 1670, 1756, 1912, 1947, 2063, 2438, 2664], 'wheezing,': [1449, 2260], 'shown': [1453, 1506, 2354, 2765], 'identification': [1462], 'individuals': [1464, 2313], 'Due': [1467], 'intermittent': [1470], 'nature': [1471], 'symptoms,': [1474], 'wheezing': [1475, 1498, 1697, 1743, 1776, 1792, 2209, 2279, 2296, 2390, 2398, 2451, 2472, 2534, 2587], 'occurring': [1476], 'any': [1478], 'previous': [1482, 1501, 1700, 2212], '12': [1483, 1575], 'months': [1484], 'used': [1487, 1532, 1579, 1694, 2135, 2223, 2299], 'define': [1489], 'Responses': [1493], 'questions': [1495], 'self-reported': [1497, 1696, 1741], '12-month': [1502, 1701, 2213], 'period': [1503, 1702, 1836, 2214, 2982], 'good': [1509], 'specificity': [1510], 'sensitivity': [1512], 'bronchial': [1515, 2315], 'hyperresponsiveness': [1516], 'core': [1530], 'question': [1531, 1603], '(ECRHS),': [1552], 'compared': [1559, 2924], 'symptoms': [1564, 1593, 1777, 1870, 1897, 1969, 2082, 2173, 2251, 2289], 'reasons,': [1570], '‘‘wheezing': [1571], 'last': [1574], 'months’’': [1576], 'response': [1585, 2384], 'determine': [1587, 2152, 2620], 'country.': [1596, 1906], 'report,': [1599, 2823, 3064], 'preferentially': [1606], 'ISAAC': [1609, 1629, 1665, 1685, 1954, 2003, 2121, 2434, 2497, 2526], 'ECRHS': [1611, 1647, 1952, 2436], 'collected': [1615], 'standardized': [1618], 'manner': [1619], 'centres': [1621, 1902, 1928], 'studies.': [1627, 2489], '13-': [1639, 2216, 2549], '14-year': [1641, 2218, 2505, 2551], 'age': [1642, 1652, 2506, 2514, 2522, 2540, 2552, 2748, 2769, 2860, 2885, 2915, 2949, 3085, 3132], 'group,': [1643, 2861], 'whereas': [1644], '20-': [1649], '44-year': [1651], 'group': [1653, 2358, 2541, 2749, 2770, 2916, 2950, 3086], 'studied.': [1655, 1929], 'where': [1658, 3099], 'centre': [1662, 2456], 'participated': [1663, 2486], 'ECRHS,': [1667, 1687, 2005], 'mean': [1669, 2467, 2529, 2631, 2670, 2964, 2981], 'value': [1672], 'country': [1675, 1918, 2638, 3165, 3350], 'used.': [1677, 2680, 2836], 'did': [1681], 'participate': [1683], 'comparable': [1688, 2106], 'defined': [1709, 1939], 'populations': [1710, 1957, 2091, 2112, 2237], 'Despite': [1715, 1979], 'acceptance': [1718], 'approach,': [1721, 2234], 'limitations': [1725, 2684], 'recognised': [1729, 1963, 3105], 'interpretation': [1732, 2171], 'data.': [1736, 2465], 'diagnostic': [1746, 1806, 2161, 2594, 3134], 'individual.': [1751], 'Wheezing': [1752], 'no': [1766, 1797, 1841, 2045], 'agreed': [1767], 'way': [1768, 3030, 3207], 'grading': [1770], 'frequency': [1774], 'identify': [1779, 2356], 'presence': [1781, 1850], 'example,': [1785], 'occasional': [1787], 'transient': [1788], 'episode': [1789], 'mild': [1791, 2259, 2288], 'requiring': [1796], 'would': [1799], 'necessarily': [1801], 'considered': [1803], 'From': [1810], 'standpoint,': [1813], 'basis': [1822, 1936, 2302], 'combined': [1824], 'history,': [1827], 'physical': [1828], 'examination,': [1829], 'physiological': [1831, 2365], 'tests,': [1832], 'often': [1833, 1899], 'time.': [1838], 'There': [1839, 2427, 2490], 'single': [1842, 2159], 'test': [1843], 'feature': [1846], 'defines': [1848], 'absence': [1852], 'particularly': [1855], 'populations.': [1861, 2601], 'As': [1862, 2602, 3261], 'result,': [1864, 3263], 'equivalent': [1873], 'Another': [1880], 'issue': [1881], 'adults,': [1888, 2481], 'variations': [1890], 'observed': [1900, 2432], 'same': [1905], 'indicates': [1908, 2270], 'reported': [1915, 1945, 2208, 2611, 2997], 'dependent': [1920, 3115], 'extent': [1923], 'sample': [1932], 'chosen,': [1933], 'geographical': [1940], 'area,': [1941], 'influences': [1943], 'rates.': [1949], 'predominantly': [1955], 'studied,': [1959], 'but': [1960], 'it': [1961, 2132, 2690, 2975, 3013, 3190], 'generally': [1971], 'rural': [1977], 'areas.': [1978], 'simple': [1984, 2019], 'questionnaires,': [1986, 2069], 'validated': [1987], 'protocols': [1989], '(including': [1990], 'translation': [1993], 'questionnaires),': [1995], 'stringent': [1997], 'quality': [1998, 3244], 'control': [1999], 'biases': [2006, 2056], 'comparability': [2009], 'unavoidable.': [2013], 'evident': [2016], 'observation': [2020], 'presented': [2028], 'translated': [2036], '50': [2039], 'languages,': [2040], 'colloquial': [2046], 'term': [2047], 'wheezing.': [2049, 2426], 'attempt': [2052, 3209], 'inherent': [2057], 'comparisons': [2060, 2089, 3009], 'video': [2071, 2099, 2387], 'questionnaire': [2072, 2100], 'shows': [2077, 2252], 'signs': [2084], 'allowing': [2088], 'languages.': [2096], 'While': [2097, 2681], 'probably': [2101], 'accurate': [2105, 3033], 'worldwide,': [2113], 'confined': [2118], 'programme': [2122], 'insufficient': [2124], 'validation': [2125, 2893, 2937], 'undertaken': [2128], 'date': [2130], 'outcome': [2139], 'variable': [2140], 'report.': [2143], 'true': [2145], 'objective': [2160], 'test,': [2162], 'methods': [2164], 'classification': [2166], 'condition,': [2169], 'differing': [2170], 'uncertain': [2181], 'influence': [2182], 'arbitrary': [2195], 'figure': [2196], '50%': [2198, 2393, 2419], '‘‘current': [2203], 'wheezing’’': [2204], '(self': [2207], 'old': [2219], 'children)': [2220], '‘‘clinical': [2228, 2308, 2609], 'asthma.’’': [2229], 'support': [2231], 'high-': [2239], 'income': [2242], 'countries:': [2243], '‘‘clinically': [2247], 'important’’': [2248], '(severe)': [2249], 'degree': [2255], 'variation': [2257, 2274, 2445, 2461, 2573], 'strong': [2263, 2430], 'correlation': [2264, 2431, 2494], 'level.': [2268], 'relative': [2285], 'over-reporting': [2286], 'highprevalence': [2291], 'detecting': [2304], 'asthma’’.': [2309], 'Hyperresponsiveness': [2316], '(BHR)': [2317], 'plus': [2318, 2335], 'wheeze': [2320, 2337, 2411], '40%': [2323], '60%': [2325], 'reporting': [2328, 2772, 2785, 2810], 'wheeze.': [2330], 'BHR': [2334], 'proposed': [2340], '‘‘gold': [2343], 'standard’’': [2344], 'identifying': [2346], 'population-based': [2350], 'having': [2352], 'requirements': [2369], 'criteria.': [2374], 'determined': [2380, 3089], 'positive': [2383], 'sequence': [2388], 'questionnaire.': [2402], 'breathlessness': [2409], '(indicative': [2412], 'clinically': [2414], 'significant': [2415], 'asthma)': [2416, 2782], 'data,': [2440], '74%': [2442], 'level': [2457], 'childhood': [2464], '88%': [2476], 'recorded': [2479, 2546], 'close': [2493], 'teenagers': [2502], '(13-': [2503], 'group)': [2507], 'young': [2509], '(6-': [2511], '7-year': [2513, 2539], 'group).': [2515], 'studied': [2520], 'programme,': [2527], '6-': [2537], '105%': [2543], 'group.': [2553, 2761, 2886], 'doctor-diagnosed': [2557], 'attacks,': [2561], 'medication': [2565], 'avoided': [2568], 'presentation': [2578], 'doctor': [2581], 'recurrent': [2586], 'episodes,': [2588], 'differences': [2592, 3055], 'labelling': [2595], 'doctors': [2599], 'result': [2604], 'rates': [2607, 2742, 2811, 2909, 2929, 2943, 3022, 3059, 3067, 3110, 3154], 'asthma’’': [2610], 'estimate.': [2618], 'To': [2619], 'country,': [2629, 2646, 2962, 3073], 'calculated': [2635], 'multiplied': [2640], 'derived': [2649, 2958, 3070], 'statistics': [2654, 2922, 3127], '2001.': [2656], 'available,': [2668], 'region': [2678, 2715], 'major': [2683], 'approach': [2687, 2706, 2803, 2888], 'evident,': [2689], 'does': [2691], 'crude': [2694, 3113], 'estimate': [2695], 'enabled': [2707], 'total': [2709, 2722], 'comparison': [2732], 'using': [2738], '5-': [2745, 2857, 2912, 2946, 3082], '34-year': [2747, 2859, 2914, 2948, 3084], 'because': [2750], 'firmly': [2757], 'established': [2758], 'false-positive': [2771], '(i.e.,': [2773, 2786], 'causes': [2777, 3323], 'falsely': [2779, 2790], 'attributed': [2780], 'false-negative': [2784], 'assigned': [2791], 'categories)': [2794], 'low.': [2797], 'However,': [2798], 'accuracy': [2800, 3121], 'declines': [2804], 'age,': [2807], 'falsepositive': [2809], '>30%': [2813], 'aged': [2816], '65': [2817], 'years': [2818, 2972, 3217, 3224, 3265, 3274], 'more.': [2820], 'country-specific': [2825], 'ICD': [2829, 2931], 'codes': [2830, 2838, 2932], '490': [2831, 2933], '493': [2833], 'incorporate': [2839], 'emphysema,': [2844], 'bronchitis,': [2846], 'bronchitis': [2848, 2880], 'specified': [2850], 'chronic.': [2854], 'figures': [2864], 'rates,': [2871], 'rarity': [2875], 'emphysema': [2882], 'supported': [2890], '14': [2899], '7': [2902], 'regions,': [2903], '493.': [2935], 'showed': [2938], 'average': [2953], '89%': [2954], 'figures.': [2959], 'presented.': [2979], '1996': [2990], '1997;': [2992], 'only': [3001], 'prior': [3003], '1992.': [3005], 'When': [3006], 'making': [3007], 'necessary': [3015], 'consider': [3018], 'compared.': [3027], 'determination': [3034], 'case': [3037, 3065, 3108], 'fatality': [3038, 3066, 3109], 'achieved': [3042], 'analysis': [3048], 'perspective': [3051], 'obtained.': [3061], 'estimate,': [3114], 'groups,': [3133], 'coding,': [3135], 'condition.': [3143], 'overall': [3151], 'format.': [3178], 'considering': [3180], 'impact': [3182], 'informative': [3192], 'extend': [3194], 'concept': [3196, 3215], 'expectancy': [3199], 'expectancy.': [3204], 'generalise': [3213], 'healthy': 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