Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2043720462', 'doi': 'https://doi.org/10.1016/0168-9525(91)90434-r', 'title': 'The polymerase in its labyrinth: mechanisms and implications of RNA recombination', 'display_name': 'The polymerase in its labyrinth: mechanisms and implications of RNA recombination', 'publication_year': 1991, 'publication_date': '1991-06-01', 'ids': {'openalex': 'https://openalex.org/W2043720462', 'doi': 'https://doi.org/10.1016/0168-9525(91)90434-r', 'mag': '2043720462', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/1712518', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/7134375'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/0168-9525(91)90434-r', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S139283865', 'display_name': 'Trends in Genetics', 'issn_l': '0168-9525', 'issn': ['0168-9525', '1362-4555'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://doi.org/10.1016/0168-9525(91)90434-r', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5088101752', 'display_name': 'Thale C. Jarvis', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}, {'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Thale C. Jarvis', 'raw_affiliation_strings': ['Department of Molecular, Cellular and Developmental Biology, Howard Hughes Medical Institute, University of Colorado, Boulder, CO 80309, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular, Cellular and Developmental Biology, Howard Hughes Medical Institute, University of Colorado, Boulder, CO 80309, USA', 'institution_ids': ['https://openalex.org/I188538660', 'https://openalex.org/I1344073410']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5073092630', 'display_name': 'Karla Kirkegaard', 'orcid': 'https://orcid.org/0000-0001-7628-3770'}, 'institutions': [{'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}, {'id': 'https://openalex.org/I188538660', 'display_name': 'University of Colorado Boulder', 'ror': 'https://ror.org/02ttsq026', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I188538660']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Karla Kirkegaard', 'raw_affiliation_strings': ['Department of Molecular, Cellular and Developmental Biology, Howard Hughes Medical Institute, University of Colorado, Boulder, CO 80309, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular, Cellular and Developmental Biology, Howard Hughes Medical Institute, University of Colorado, Boulder, CO 80309, USA', 'institution_ids': ['https://openalex.org/I1344073410', 'https://openalex.org/I188538660']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 6830, 'currency': 'USD', 'value_usd': 6830, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.933, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 93, 'citation_normalized_percentile': {'value': 0.825193, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '7', 'issue': '6', 'first_page': '186', 'last_page': '191'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11112', 'display_name': 'Aetiology, Diagnosis, and Management of Myocarditis', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11112', 'display_name': 'Aetiology, Diagnosis, and Management of Myocarditis', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10878', 'display_name': 'Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10604', 'display_name': 'Regulation of RNA Processing and Function', 'score': 0.9915, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/genome-engineering', 'display_name': 'Genome Engineering', 'score': 0.453948}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.87138116}, {'id': 'https://openalex.org/C156695909', 'wikidata': 'https://www.wikidata.org/wiki/Q3373825', 'display_name': 'Recombination', 'level': 3, 'score': 0.76165533}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.700234}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.60514975}, {'id': 'https://openalex.org/C141231307', 'wikidata': 'https://www.wikidata.org/wiki/Q7020', 'display_name': 'Genome', 'level': 3, 'score': 0.5645728}, {'id': 'https://openalex.org/C89611455', 'wikidata': 'https://www.wikidata.org/wiki/Q6804646', 'display_name': 'Mechanism (biology)', 'level': 2, 'score': 0.5355185}, {'id': 'https://openalex.org/C101434241', 'wikidata': 'https://www.wikidata.org/wiki/Q211675', 'display_name': 'Genetic recombination', 'level': 4, 'score': 0.47477815}, {'id': 'https://openalex.org/C21786251', 'wikidata': 'https://www.wikidata.org/wiki/Q14886350', 'display_name': 'RNA editing', 'level': 4, 'score': 0.44337893}, {'id': 'https://openalex.org/C82381507', 'wikidata': 'https://www.wikidata.org/wiki/Q416878', 'display_name': 'Polymerase', 'level': 3, 'score': 0.4177242}, {'id': 'https://openalex.org/C78458016', 'wikidata': 'https://www.wikidata.org/wiki/Q840400', 'display_name': 'Evolutionary biology', 'level': 1, 'score': 0.41513664}, {'id': 'https://openalex.org/C2776449523', 'wikidata': 'https://www.wikidata.org/wiki/Q272631', 'display_name': 'RNA polymerase', 'level': 4, 'score': 0.41343623}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.33138573}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.29331058}, {'id': 'https://openalex.org/C138885662', 'wikidata': 'https://www.wikidata.org/wiki/Q5891', 'display_name': 'Philosophy', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C111472728', 'wikidata': 'https://www.wikidata.org/wiki/Q9471', 'display_name': 'Epistemology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D012321', 'descriptor_name': 'DNA-Directed RNA Polymerases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012313', 'descriptor_name': 'RNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012328', 'descriptor_name': 'RNA Viruses', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D011995', 'descriptor_name': 'Recombination, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D005075', 'descriptor_name': 'Biological Evolution', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012321', 'descriptor_name': 'DNA-Directed RNA Polymerases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014644', 'descriptor_name': 'Genetic Variation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008957', 'descriptor_name': 'Models, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012328', 'descriptor_name': 'RNA Viruses', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013698', 'descriptor_name': 'Templates, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/0168-9525(91)90434-r', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S139283865', 'display_name': 'Trends in Genetics', 'issn_l': '0168-9525', 'issn': ['0168-9525', '1362-4555'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc7134375', 'pdf_url': 'https://europepmc.org/articles/pmc7134375?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134375', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/1712518', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/0168-9525(91)90434-r', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S139283865', 'display_name': 'Trends in Genetics', 'issn_l': '0168-9525', 'issn': ['0168-9525', '1362-4555'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 41, 'referenced_works': ['https://openalex.org/W1508030956', 'https://openalex.org/W1561528540', 'https://openalex.org/W1580027475', 'https://openalex.org/W1586964416', 'https://openalex.org/W1801780041', 'https://openalex.org/W1828812071', 'https://openalex.org/W1921262380', 'https://openalex.org/W1964689773', 'https://openalex.org/W1968038125', 'https://openalex.org/W1973655646', 'https://openalex.org/W1973968273', 'https://openalex.org/W1980437255', 'https://openalex.org/W1980624564', 'https://openalex.org/W1988411415', 'https://openalex.org/W1989154040', 'https://openalex.org/W1993486727', 'https://openalex.org/W2001297399', 'https://openalex.org/W2001505139', 'https://openalex.org/W2002842607', 'https://openalex.org/W2008464428', 'https://openalex.org/W2022291864', 'https://openalex.org/W2023719523', 'https://openalex.org/W2027271983', 'https://openalex.org/W2029402164', 'https://openalex.org/W2033988102', 'https://openalex.org/W2037713473', 'https://openalex.org/W2040722089', 'https://openalex.org/W2041282645', 'https://openalex.org/W2060190614', 'https://openalex.org/W2071944390', 'https://openalex.org/W2073004681', 'https://openalex.org/W2078354583', 'https://openalex.org/W2086657415', 'https://openalex.org/W2143010405', 'https://openalex.org/W2148141318', 'https://openalex.org/W2153359028', 'https://openalex.org/W2730153167', 'https://openalex.org/W346584939', 'https://openalex.org/W4239862408', 'https://openalex.org/W4252503192', 'https://openalex.org/W44757669'], 'related_works': ['https://openalex.org/W4242086171', 'https://openalex.org/W2970236921', 'https://openalex.org/W2226255475', 'https://openalex.org/W2184214635', 'https://openalex.org/W2071784810', 'https://openalex.org/W1998410376', 'https://openalex.org/W1866756245', 'https://openalex.org/W1578419118', 'https://openalex.org/W125907854', 'https://openalex.org/W103424567'], 'abstract_inverted_index': {'The': [0], 'wide': [1], 'variety': [2], 'of': [3, 19, 32], 'RNA': [4, 20, 33], 'viruses,': [5], 'and': [6, 35, 41], 'the': [7, 17, 30], 'diseases': [8], 'associated': [9], 'with': [10], 'them,': [11], 'may': [12], 'result': [13], 'in': [14, 43], 'part': [15], 'from': [16], 'capacity': [18], 'genomes': [21], 'to': [22], 'evolve': [23], 'through': [24], 'genetic': [25], 'recombination.': [26], 'Here': [27], 'we': [28], 'address': [29], 'mechanism': [31], 'recombination,': [34], 'ask': [36], 'questions': [37], 'about': [38], 'its': [39], 'prevalence': [40], 'purpose': [42], 'nature.': [44]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2043720462', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 5}], 'updated_date': '2024-09-09T11:20:08.435427', 'created_date': '2016-06-24'}