Publication Information

{'id': 'https://openalex.org/W2043330551', 'doi': 'https://doi.org/10.1021/bi049528x', 'title': 'Lipoyl Synthase Requires Two Equivalents of <i>S</i>-Adenosyl-<scp>l</scp>-methionine To Synthesize One Equivalent of Lipoic Acid', 'display_name': 'Lipoyl Synthase Requires Two Equivalents of <i>S</i>-Adenosyl-<scp>l</scp>-methionine To Synthesize One Equivalent of Lipoic Acid', 'publication_year': 2004, 'publication_date': '2004-05-04', 'ids': {'openalex': 'https://openalex.org/W2043330551', 'doi': 'https://doi.org/10.1021/bi049528x', 'mag': '2043330551', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15157071'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/bi049528x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104038378', 'display_name': 'Biochemistry', 'issn_l': '0006-2960', 'issn': ['0006-2960', '1520-4995', '1943-295X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5069952389', 'display_name': 'Robert M. Cicchillo', 'orcid': 'https://orcid.org/0000-0003-2830-3807'}, 'institutions': [{'id': 'https://openalex.org/I130769515', 'display_name': 'Pennsylvania State University', 'ror': 'https://ror.org/04p491231', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130769515']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert M. Cicchillo', 'raw_affiliation_strings': ['Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802'], 'affiliations': [{'raw_affiliation_string': 'Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802', 'institution_ids': ['https://openalex.org/I130769515']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011027590', 'display_name': 'David F. Iwig', 'orcid': 'https://orcid.org/0000-0001-8394-184X'}, 'institutions': [{'id': 'https://openalex.org/I130769515', 'display_name': 'Pennsylvania State University', 'ror': 'https://ror.org/04p491231', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130769515']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David F. Iwig', 'raw_affiliation_strings': ['Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802'], 'affiliations': [{'raw_affiliation_string': 'Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802', 'institution_ids': ['https://openalex.org/I130769515']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006267438', 'display_name': 'A. Daniel Jones', 'orcid': 'https://orcid.org/0000-0002-7408-6690'}, 'institutions': [{'id': 'https://openalex.org/I130769515', 'display_name': 'Pennsylvania State University', 'ror': 'https://ror.org/04p491231', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130769515']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'A. Daniel Jones', 'raw_affiliation_strings': ['Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802'], 'affiliations': [{'raw_affiliation_string': 'Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802', 'institution_ids': ['https://openalex.org/I130769515']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030479167', 'display_name': 'Natasha M. Nesbitt', 'orcid': 'https://orcid.org/0000-0001-5549-0383'}, 'institutions': [{'id': 'https://openalex.org/I130769515', 'display_name': 'Pennsylvania State University', 'ror': 'https://ror.org/04p491231', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130769515']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Natasha M. Nesbitt', 'raw_affiliation_strings': ['Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802'], 'affiliations': [{'raw_affiliation_string': 'Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802', 'institution_ids': ['https://openalex.org/I130769515']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035031291', 'display_name': 'Camelia Baleanu‐Gogonea', 'orcid': 'https://orcid.org/0000-0003-4147-5347'}, 'institutions': [{'id': 'https://openalex.org/I130769515', 'display_name': 'Pennsylvania State University', 'ror': 'https://ror.org/04p491231', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130769515']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Camelia Baleanu-Gogonea', 'raw_affiliation_strings': ['Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802'], 'affiliations': [{'raw_affiliation_string': 'Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802', 'institution_ids': ['https://openalex.org/I130769515']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058553705', 'display_name': 'Matthew G. Souder', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I130769515', 'display_name': 'Pennsylvania State University', 'ror': 'https://ror.org/04p491231', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130769515']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Matthew G. Souder', 'raw_affiliation_strings': ['Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802'], 'affiliations': [{'raw_affiliation_string': 'Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802', 'institution_ids': ['https://openalex.org/I130769515']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007958693', 'display_name': 'Loretta Tu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I130769515', 'display_name': 'Pennsylvania State University', 'ror': 'https://ror.org/04p491231', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130769515']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Loretta Tu', 'raw_affiliation_strings': ['Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802'], 'affiliations': [{'raw_affiliation_string': 'Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802', 'institution_ids': ['https://openalex.org/I130769515']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5045998043', 'display_name': 'Squire J. Booker', 'orcid': 'https://orcid.org/0000-0002-7211-5937'}, 'institutions': [{'id': 'https://openalex.org/I130769515', 'display_name': 'Pennsylvania State University', 'ror': 'https://ror.org/04p491231', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I130769515']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Squire J. Booker', 'raw_affiliation_strings': ['Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802'], 'affiliations': [{'raw_affiliation_string': 'Departments of Biochemistry and Molecular Biology and of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802', 'institution_ids': ['https://openalex.org/I130769515']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 5.737, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 181, 'citation_normalized_percentile': {'value': 0.999359, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '43', 'issue': '21', 'first_page': '6378', 'last_page': '6386'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12915', 'display_name': 'Biochemical Acid Research Studies', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12915', 'display_name': 'Biochemical Acid Research Studies', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12688', 'display_name': 'Microbial metabolism and enzyme function', 'score': 0.9976, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12827', 'display_name': 'Biochemical and Molecular Research', 'score': 0.995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.7731948}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.7118425}, {'id': 'https://openalex.org/C197957613', 'wikidata': 'https://www.wikidata.org/wiki/Q407280', 'display_name': 'Cofactor', 'level': 3, 'score': 0.6204637}, {'id': 'https://openalex.org/C112243037', 'wikidata': 'https://www.wikidata.org/wiki/Q22327117', 'display_name': 'ATP synthase', 'level': 3, 'score': 0.5685143}, {'id': 'https://openalex.org/C104292427', 'wikidata': 'https://www.wikidata.org/wiki/Q899781', 'display_name': 'Protein subunit', 'level': 3, 'score': 0.54960877}, {'id': 'https://openalex.org/C2779491571', 'wikidata': 'https://www.wikidata.org/wiki/Q312229', 'display_name': 'Lipoic acid', 'level': 3, 'score': 0.46706635}, {'id': 'https://openalex.org/C2776414213', 'wikidata': 'https://www.wikidata.org/wiki/Q183290', 'display_name': 'Serine', 'level': 3, 'score': 0.44982475}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.37882707}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.37858295}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C2778004101', 'wikidata': 'https://www.wikidata.org/wiki/Q133948', 'display_name': 'Antioxidant', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012436', 'descriptor_name': 'S-Adenosylmethionine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008063', 'descriptor_name': 'Thioctic Acid', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002853', 'descriptor_name': 'Chromatography, Liquid', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D002853', 'descriptor_name': 'Chromatography, Liquid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003839', 'descriptor_name': 'Deoxyadenosines', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D003839', 'descriptor_name': 'Deoxyadenosines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006859', 'descriptor_name': 'Hydrogen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013058', 'descriptor_name': 'Mass Spectrometry', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D013058', 'descriptor_name': 'Mass Spectrometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015202', 'descriptor_name': 'Protein Engineering', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015202', 'descriptor_name': 'Protein Engineering', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D012436', 'descriptor_name': 'S-Adenosylmethionine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012436', 'descriptor_name': 'S-Adenosylmethionine', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D008063', 'descriptor_name': 'Thioctic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008063', 'descriptor_name': 'Thioctic Acid', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/bi049528x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104038378', 'display_name': 'Biochemistry', 'issn_l': '0006-2960', 'issn': ['0006-2960', '1520-4995', '1943-295X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15157071', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Clean water and sanitation', 'id': 'https://metadata.un.org/sdg/6', 'score': 0.7}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 21, 'referenced_works': ['https://openalex.org/W1565494682', 'https://openalex.org/W1582536955', 'https://openalex.org/W1605201659', 'https://openalex.org/W1911545410', 'https://openalex.org/W1950687899', 'https://openalex.org/W1968917216', 'https://openalex.org/W1994884882', 'https://openalex.org/W2002549784', 'https://openalex.org/W2004790702', 'https://openalex.org/W2012036296', 'https://openalex.org/W2021944478', 'https://openalex.org/W2027622313', 'https://openalex.org/W2047142948', 'https://openalex.org/W2072289725', 'https://openalex.org/W2092152103', 'https://openalex.org/W2164545938', 'https://openalex.org/W2169007852', 'https://openalex.org/W2227762204', 'https://openalex.org/W2314225431', 'https://openalex.org/W2406743185', 'https://openalex.org/W2949508003'], 'related_works': ['https://openalex.org/W4233494496', 'https://openalex.org/W2375649700', 'https://openalex.org/W2074690676', 'https://openalex.org/W2044417247', 'https://openalex.org/W2037673479', 'https://openalex.org/W2025878174', 'https://openalex.org/W2024093725', 'https://openalex.org/W1970662834', 'https://openalex.org/W1969789435', 'https://openalex.org/W1965539357'], 'abstract_inverted_index': {'Lipoyl': [0], 'synthase': [1, 80, 138], '(LipA)': [2], 'catalyzes': [3], 'the': [4, 7, 18, 28, 49, 71, 121, 130, 144, 148, 153, 181, 185, 189, 204, 216, 221], 'formation': [5], 'of': [6, 21, 30, 39, 70, 84, 89, 98, 123, 147, 152, 184, 188, 240, 249], 'lipoyl': [8, 50, 79, 137, 267], 'cofactor,': [9], 'which': [10, 103, 116, 258], 'is': [11, 52, 81, 104, 194, 206], 'employed': [12], 'by': [13, 226], 'several': [14], 'multienzyme': [15], 'complexes': [16], 'for': [17, 136, 198], 'oxidative': [19], 'decarboxylation': [20], 'various': [22], 'α-keto': [23], 'acids,': [24], 'as': [25, 27, 95, 224], 'well': [26], 'cleavage': [29, 122, 191], 'glycine': [31, 190], 'into': [32], 'CO2': [33], 'and': [34, 74, 167, 251], 'NH3,': [35], 'with': [36, 254], 'concomitant': [37], 'transfer': [38, 228], 'its': [40, 209], 'α-carbon': [41], 'to': [42, 59, 129, 142, 231, 264], 'tetrahydrofolate,': [43], 'generating': [44], 'N5,N10-methylenetetrahydrofolate.': [45], 'In': [46], 'each': [47, 109], 'case,': [48], 'cofactor': [51, 205], 'tethered': [53], 'covalently': [54], 'in': [55, 108, 127, 245, 257], 'an': [56, 105, 118], 'amide': [57], 'linkage': [58], 'a': [60, 66, 82, 85, 96, 99, 196, 255], 'conserved': [61], 'lysine': [62], 'residue': [63], 'located': [64], 'on': [65, 208, 220], 'designated': [67], 'lipoyl-bearing': [68, 149, 186], 'subunit': [69, 150, 187], 'complex.': [72], 'Genetic': [73], 'biochemical': [75], 'studies': [76], 'suggest': [77], 'that': [78, 91, 180, 203, 215, 237], 'member': [83], 'newly': [86], 'established': [87], 'class': [88], 'metalloenzymes': [90], 'use': [92], 'S-adenosyl-l-methionine': [93], '(AdoMet)': [94], 'source': [97], "5'-deoxyadenosyl": [100], 'radical': [101], "(5'-dA•),": [102], 'obligate': [106], 'intermediate': [107], 'reaction.': [110], 'These': [111], 'enzymes': [112], 'contain': [113], 'iron−sulfur': [114], 'clusters,': [115], 'provide': [117], 'electron': [119], 'during': [120], 'AdoMet,': [124], 'forming': [125, 246], 'l-methionine': [126], 'addition': [128], 'primary': [131], 'radical.': [132], 'Recently,': [133], 'one': [134, 266], 'substrate': [135, 197], 'has': [139], 'been': [140], 'shown': [141], 'be': [143], 'octanoylated': [145, 182], 'derivative': [146, 183], '(E2)': [151], 'pyruvate': [154], 'dehydrogenase': [155], 'complex': [156], '[Zhao,': [157], 'S.,': [158], 'Miller,': [159], 'J.': [160, 169], 'R.,': [161], 'Jian,': [162], 'Y.,': [163], 'Marletta,': [164], 'M.': [165], 'A.,': [166], 'Cronan,': [168], 'E.,': [170], 'Jr.': [171], '(2003)': [172], 'Chem.': [173], 'Biol.': [174], '10,': [175], '1293−1302].': [176], 'Herein,': [177], 'we': [178, 213], 'show': [179, 214], 'system': [192], '(H-protein)': [193], 'also': [195], 'LipA,': [199], 'providing': [200], 'further': [201], 'evidence': [202], 'synthesized': [207], 'target': [210], 'protein.': [211], 'Moreover,': [212], "5'-dA•": [217], 'acts': [218], 'directly': [219], 'octanoyl': [222], 'substrate,': [223], 'evidenced': [225], 'deuterium': [227], 'from': [229], '[octanoyl-d15]H-protein': [230], "5'-deoxyadenosine.": [232], 'Last,': [233], 'our': [234], 'data': [235], 'indicate': [236], '2': [238], 'equiv': [239, 248], 'AdoMet': [241], 'are': [242, 252, 262], 'cleaved': [243], 'irreversibly': [244], '1': [247], '[lipoyl]H-protein': [250], 'consistent': [253], 'model': [256], 'two': [259], 'LipA': [260], 'proteins': [261], 'required': [263], 'synthesize': [265], 'group.': [268]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2043330551', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 16}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 6}, {'year': 2018, 'cited_by_count': 13}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 10}, {'year': 2015, 'cited_by_count': 8}, {'year': 2014, 'cited_by_count': 15}, {'year': 2013, 'cited_by_count': 8}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2025-01-07T11:30:38.536608', 'created_date': '2016-06-24'}