Publication Information

{'id': 'https://openalex.org/W2043069063', 'doi': 'https://doi.org/10.1001/archpsyc.1991.01810300025004', 'title': 'The Mechanisms of Action of Lithium', 'display_name': 'The Mechanisms of Action of Lithium', 'publication_year': 1991, 'publication_date': '1991-06-01', 'ids': {'openalex': 'https://openalex.org/W2043069063', 'doi': 'https://doi.org/10.1001/archpsyc.1991.01810300025004', 'mag': '2043069063', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/1645514'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1001/archpsyc.1991.01810300025004', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S126359496', 'display_name': 'Archives of General Psychiatry', 'issn_l': '0003-990X', 'issn': ['0003-990X', '1538-3636'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320259', 'host_organization_name': 'American Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310320259'], 'host_organization_lineage_names': ['American Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5087714828', 'display_name': 'Emile D. Risby', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210167247', 'display_name': 'National Institute of Mental Health', 'ror': 'https://ror.org/05xj56w78', 'country_code': 'CZ', 'type': 'facility', 'lineage': ['https://openalex.org/I4210167247']}], 'countries': ['CZ'], 'is_corresponding': True, 'raw_author_name': 'Emile D. Risby', 'raw_affiliation_strings': ['Section on Clinical Pharmacology, National Institute of Mental Health, Bethesda, Md 20892.'], 'affiliations': [{'raw_affiliation_string': 'Section on Clinical Pharmacology, National Institute of Mental Health, Bethesda, Md 20892.', 'institution_ids': ['https://openalex.org/I4210167247']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5087714828'], 'corresponding_institution_ids': ['https://openalex.org/I4210167247'], 'apc_list': None, 'apc_paid': None, 'fwci': 9.051, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 96, 'citation_normalized_percentile': {'value': 0.905171, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '48', 'issue': '6', 'first_page': '513', 'last_page': '513'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10854', 'display_name': 'Bipolar Disorder and Treatment', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10854', 'display_name': 'Bipolar Disorder and Treatment', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 0.9962, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10448', 'display_name': 'Memory and Neural Mechanisms', 'score': 0.9866, 'subfield': {'id': 'https://openalex.org/subfields/2805', 'display_name': 'Cognitive Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.7514136}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.7379839}, {'id': 'https://openalex.org/C2780069284', 'wikidata': 'https://www.wikidata.org/wiki/Q5198121', 'display_name': 'Cyclase', 'level': 3, 'score': 0.7011527}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.64533997}, {'id': 'https://openalex.org/C2778541603', 'wikidata': 'https://www.wikidata.org/wiki/Q152763', 'display_name': 'Lithium (medication)', 'level': 2, 'score': 0.64013904}, {'id': 'https://openalex.org/C180526460', 'wikidata': 'https://www.wikidata.org/wiki/Q356240', 'display_name': 'Adenylate kinase', 'level': 3, 'score': 0.62835217}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.4234187}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.20407268}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.1357061}], 'mesh': [{'descriptor_ui': 'D000262', 'descriptor_name': 'Adenylyl Cyclases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D005459', 'descriptor_name': 'Fluorides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D008094', 'descriptor_name': 'Lithium', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D011943', 'descriptor_name': 'Receptors, Adrenergic, beta', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000262', 'descriptor_name': 'Adenylyl Cyclases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000339', 'descriptor_name': 'Affect', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000339', 'descriptor_name': 'Affect', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D001792', 'descriptor_name': 'Blood Platelets', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001792', 'descriptor_name': 'Blood Platelets', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D001792', 'descriptor_name': 'Blood Platelets', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D002586', 'descriptor_name': 'Cesium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002586', 'descriptor_name': 'Cesium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006160', 'descriptor_name': 'Guanosine Triphosphate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006160', 'descriptor_name': 'Guanosine Triphosphate', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006160', 'descriptor_name': 'Guanosine Triphosphate', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D006165', 'descriptor_name': 'Guanylyl Imidodiphosphate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006165', 'descriptor_name': 'Guanylyl Imidodiphosphate', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008094', 'descriptor_name': 'Lithium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008094', 'descriptor_name': 'Lithium', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D008094', 'descriptor_name': 'Lithium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D016651', 'descriptor_name': 'Lithium Carbonate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008214', 'descriptor_name': 'Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008214', 'descriptor_name': 'Lymphocytes', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D008214', 'descriptor_name': 'Lymphocytes', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009638', 'descriptor_name': 'Norepinephrine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009638', 'descriptor_name': 'Norepinephrine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011446', 'descriptor_name': 'Prospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011943', 'descriptor_name': 'Receptors, Adrenergic, beta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011943', 'descriptor_name': 'Receptors, Adrenergic, beta', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D015290', 'descriptor_name': 'Second Messenger Systems', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D015290', 'descriptor_name': 'Second Messenger Systems', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012701', 'descriptor_name': 'Serotonin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012701', 'descriptor_name': 'Serotonin', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D012701', 'descriptor_name': 'Serotonin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1001/archpsyc.1991.01810300025004', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S126359496', 'display_name': 'Archives of General Psychiatry', 'issn_l': '0003-990X', 'issn': ['0003-990X', '1538-3636'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320259', 'host_organization_name': 'American Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310320259'], 'host_organization_lineage_names': ['American Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/1645514', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 103, 'referenced_works': ['https://openalex.org/W1595160908', 'https://openalex.org/W1775749144', 'https://openalex.org/W1865482726', 'https://openalex.org/W1889236699', 'https://openalex.org/W1927894522', 'https://openalex.org/W1958331420', 'https://openalex.org/W1963563875', 'https://openalex.org/W1963622332', 'https://openalex.org/W1964839077', 'https://openalex.org/W196940827', 'https://openalex.org/W1973261604', 'https://openalex.org/W1974016360', 'https://openalex.org/W1974505399', 'https://openalex.org/W1975867623', 'https://openalex.org/W1976904248', 'https://openalex.org/W1977234592', 'https://openalex.org/W1977660551', 'https://openalex.org/W1978492878', 'https://openalex.org/W1980840240', 'https://openalex.org/W1982344927', 'https://openalex.org/W1987515973', 'https://openalex.org/W1988625476', 'https://openalex.org/W1991726951', 'https://openalex.org/W1992498254', 'https://openalex.org/W1993282564', 'https://openalex.org/W1998701465', 'https://openalex.org/W2001215218', 'https://openalex.org/W2001256704', 'https://openalex.org/W2004475074', 'https://openalex.org/W2009697954', 'https://openalex.org/W2010299939', 'https://openalex.org/W2015379568', 'https://openalex.org/W2023772121', 'https://openalex.org/W2024956593', 'https://openalex.org/W2025743030', 'https://openalex.org/W2026594977', 'https://openalex.org/W2028599453', 'https://openalex.org/W2030307222', 'https://openalex.org/W2031458084', 'https://openalex.org/W2032924239', 'https://openalex.org/W2034984305', 'https://openalex.org/W2039559232', 'https://openalex.org/W2042888367', 'https://openalex.org/W2049197899', 'https://openalex.org/W2050083058', 'https://openalex.org/W2050923935', 'https://openalex.org/W2052570973', 'https://openalex.org/W2053922838', 'https://openalex.org/W2054745706', 'https://openalex.org/W2056272943', 'https://openalex.org/W2058282000', 'https://openalex.org/W2058329827', 'https://openalex.org/W2058636320', 'https://openalex.org/W2059063184', 'https://openalex.org/W2060395067', 'https://openalex.org/W2060404435', 'https://openalex.org/W2061292709', 'https://openalex.org/W2062929908', 'https://openalex.org/W2063253045', 'https://openalex.org/W2065230351', 'https://openalex.org/W2067869569', 'https://openalex.org/W2068917030', 'https://openalex.org/W2068990274', 'https://openalex.org/W2071036129', 'https://openalex.org/W2071995561', 'https://openalex.org/W2072895481', 'https://openalex.org/W2073763080', 'https://openalex.org/W2079502063', 'https://openalex.org/W2080875376', 'https://openalex.org/W2082951032', 'https://openalex.org/W2083307191', 'https://openalex.org/W2084073391', 'https://openalex.org/W2085449450', 'https://openalex.org/W2085968319', 'https://openalex.org/W2087368964', 'https://openalex.org/W2089686383', 'https://openalex.org/W2090819927', 'https://openalex.org/W2091289917', 'https://openalex.org/W2094167557', 'https://openalex.org/W2095485211', 'https://openalex.org/W2103717949', 'https://openalex.org/W2103779140', 'https://openalex.org/W2108143899', 'https://openalex.org/W2125662401', 'https://openalex.org/W2127576431', 'https://openalex.org/W2131524293', 'https://openalex.org/W2135004468', 'https://openalex.org/W2135809214', 'https://openalex.org/W2152744673', 'https://openalex.org/W2155250197', 'https://openalex.org/W2165095081', 'https://openalex.org/W2268324534', 'https://openalex.org/W2330454823', 'https://openalex.org/W2410276771', 'https://openalex.org/W2414498190', 'https://openalex.org/W2423666042', 'https://openalex.org/W2463531151', 'https://openalex.org/W2468119228', 'https://openalex.org/W2471547884', 'https://openalex.org/W2473734286', 'https://openalex.org/W376578160', 'https://openalex.org/W81176037', 'https://openalex.org/W957480215'], 'related_works': ['https://openalex.org/W4211194360', 'https://openalex.org/W4211088770', 'https://openalex.org/W3103481565', 'https://openalex.org/W2406327875', 'https://openalex.org/W2079960837', 'https://openalex.org/W2053922838', 'https://openalex.org/W1983113419', 'https://openalex.org/W1964888906', 'https://openalex.org/W180243494', 'https://openalex.org/W17693006'], 'abstract_inverted_index': {'As': [0], 'part': [1], 'of': [2, 5, 8, 35, 137, 146, 208], 'a': [3, 202], 'study': [4], 'the': [6, 135, 158], 'effects': [7, 45, 105, 168, 183, 217], 'lithium': [9, 36, 71, 121], 'carbonate': [10], 'on': [11, 46, 106, 169, 184, 212], 'neurochemical': [12], 'function': [13, 186, 226], 'in': [14, 38, 75, 196, 201, 222, 224], 'man,': [15], 'platelet': [16, 47], 'and': [17, 22, 31, 48, 56, 78, 116, 119, 161, 189], 'lymphocyte': [18, 23, 49, 150], 'adenylate': [19, 50, 64, 81, 107], 'cyclase': [20, 51, 65, 82, 108], 'activity': [21, 66, 83, 88, 109], 'beta-adrenergic': [24, 151, 159], 'receptor': [25, 160], 'binding': [26, 127, 148], 'characteristics': [27], 'were': [28], 'determined': [29], 'before': [30], 'after': [32, 92], '2': [33], 'weeks': [34], 'treatment': [37, 132], '10': [39], 'normal': [40], 'volunteers.': [41], 'Lithium': [42, 131, 165], 'had': [43, 166], 'differential': [44], 'activity.': [52], 'In': [53], 'platelets,': [54], 'basal': [55, 87], 'stimulated': [57], '(guanyl': [58], 'imidodiphosphate': [59], '[Gpp[NH]p]': [60], 'or': [61], 'cesium': [62, 79], 'fluoride)': [63], 'was': [67, 84, 89], 'significantly': [68, 133], 'augmented': [69], 'by': [70], 'treatment.': [72], 'By': [73], 'contrast,': [74], 'lymphocytes,': [76], 'Gpp(NH)p-': [77], 'fluoride-stimulated': [80], 'unaffected,': [85], 'while': [86], 'decreased': [90], 'modestly': [91], 'lithium.': [93], 'These': [94, 216], 'results': [95], 'are': [96, 110], 'consistent': [97], 'with': [98, 112, 124, 172], 'preclinical': [99], 'studies': [100], 'that': [101, 103, 120, 175, 227], 'suggest': [102], "lithium's": [104, 232], 'specific': [111], 'respect': [113], 'to': [114, 139, 149, 154, 179, 193, 231], 'tissue': [115], 'brain': [117], 'region': [118], 'may': [122, 210, 219, 228], 'interfere': [123], 'guanine': [125], 'nucleotide': [126], '(G)': [128], 'protein': [129], 'function.': [130], 'increased': [134], 'ratio': [136], 'low-': [138], 'high-affinity': [140], 'dissociation': [141], 'constants': [142], 'for': [143], 'agonist': [144], 'displacement': [145], 'antagonist': [147], 'receptors': [152], '(thought': [153], 'reflect': [155], 'coupling': [156], 'between': [157], 'stimulatory': [162], 'G': [163], 'protein).': [164], 'significant': [167], 'measures': [170], 'associated': [171], 'signal': [173, 213], 'transduction': [174, 214], 'might': [176], 'be': [177, 211, 220, 229], 'contrasted': [178], 'its': [180], 'more': [181], 'subtle': [182], 'neuronal': [185], '(norepinephrine': [187], 'release)': [188], 'neuroendocrine': [190], 'systems': [191], '(responses': [192], 'serotoninergic': [194], 'challenge)': [195], 'these': [197], 'same': [198], 'subjects': [199], '(reported': [200], 'companion': [203], 'article).': [204], "Lithium's": [205], 'primary': [206], 'site': [207], 'action': [209], 'mechanisms.': [215], 'subsequently': [218], 'manifested': [221], 'changes': [223], 'neurotransmitter': [225], 'important': [230], 'mood-stabilizing': [233], 'actions.': [234]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2043069063', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-08T17:45:44.747760', 'created_date': '2016-06-24'}