Publication Information

{'id': 'https://openalex.org/W2042531378', 'doi': 'https://doi.org/10.1002/jcp.21776', 'title': 'CCL5 secreted by senescent aged fibroblasts induces proliferation of prostate epithelial cells and expression of genes that modulate angiogenesis', 'display_name': 'CCL5 secreted by senescent aged fibroblasts induces proliferation of prostate epithelial cells and expression of genes that modulate angiogenesis', 'publication_year': 2009, 'publication_date': '2009-04-09', 'ids': {'openalex': 'https://openalex.org/W2042531378', 'doi': 'https://doi.org/10.1002/jcp.21776', 'mag': '2042531378', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19360811', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2846281'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/jcp.21776', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S43643205', 'display_name': 'Journal of Cellular Physiology', 'issn_l': '0021-9541', 'issn': ['0021-9541', '1097-4652'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc2846281?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5028647192', 'display_name': 'Daniel Eyman', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802336062', 'display_name': 'Harborview Medical Center', 'ror': 'https://ror.org/059jq5127', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802336062']}, {'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'D. Eyman', 'raw_affiliation_strings': ['Department of Medicine, Harborview Medical Center, University of Washington, Seattle, WA 98104, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Harborview Medical Center, University of Washington, Seattle, WA 98104, USA', 'institution_ids': ['https://openalex.org/I2802336062', 'https://openalex.org/I201448701']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046611314', 'display_name': 'Mamatha Damodarasamy', 'orcid': 'https://orcid.org/0009-0001-6121-8420'}, 'institutions': [{'id': 'https://openalex.org/I2802336062', 'display_name': 'Harborview Medical Center', 'ror': 'https://ror.org/059jq5127', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802336062']}, {'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'M. Damodarasamy', 'raw_affiliation_strings': ['Department of Medicine, Harborview Medical Center, University of Washington, Seattle, Washington.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Harborview Medical Center, University of Washington, Seattle, Washington.', 'institution_ids': ['https://openalex.org/I2802336062', 'https://openalex.org/I201448701']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112166455', 'display_name': 'S R Plymate', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210094549', 'display_name': 'VA Puget Sound Health Care System', 'ror': 'https://ror.org/00ky3az31', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210094549', 'https://openalex.org/I4210138024']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'S.R. Plymate', 'raw_affiliation_strings': ['Veterans Affairs Puget Sound Health Care System Seattle Washington'], 'affiliations': [{'raw_affiliation_string': 'Veterans Affairs Puget Sound Health Care System Seattle Washington', 'institution_ids': ['https://openalex.org/I4210094549']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5007982307', 'display_name': 'May J. Reed', 'orcid': 'https://orcid.org/0000-0002-6917-9286'}, 'institutions': [{'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}, {'id': 'https://openalex.org/I2802336062', 'display_name': 'Harborview Medical Center', 'ror': 'https://ror.org/059jq5127', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802336062']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'M.J. Reed', 'raw_affiliation_strings': ['Department of Medicine, Harborview Medical Center, University of Washington, Seattle, Washington.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Harborview Medical Center, University of Washington, Seattle, Washington.', 'institution_ids': ['https://openalex.org/I201448701', 'https://openalex.org/I2802336062']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4940, 'currency': 'USD', 'value_usd': 4940, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.125, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 56, 'citation_normalized_percentile': {'value': 0.914985, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '220', 'issue': '2', 'first_page': '376', 'last_page': '381'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10580', 'display_name': 'Immunotherapy and Immune Responses', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10580', 'display_name': 'Immunotherapy and Immune Responses', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10831', 'display_name': 'Cell Adhesion Molecules Research', 'score': 0.9958, 'subfield': {'id': 'https://openalex.org/subfields/2723', 'display_name': 'Immunology and Allergy'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/ccl5', 'display_name': 'CCL5', 'score': 0.94268465}, {'id': 'https://openalex.org/keywords/cxcl5', 'display_name': 'CXCL5', 'score': 0.4283609}, {'id': 'https://openalex.org/keywords/interleukin-8', 'display_name': 'Interleukin 8', 'score': 0.41900635}], 'concepts': [{'id': 'https://openalex.org/C116484652', 'wikidata': 'https://www.wikidata.org/wiki/Q3492926', 'display_name': 'CCL5', 'level': 5, 'score': 0.94268465}, {'id': 'https://openalex.org/C13373296', 'wikidata': 'https://www.wikidata.org/wiki/Q421866', 'display_name': 'Chemokine', 'level': 3, 'score': 0.81379545}, {'id': 'https://openalex.org/C101666144', 'wikidata': 'https://www.wikidata.org/wiki/Q2587862', 'display_name': 'CCL2', 'level': 4, 'score': 0.8006257}, {'id': 'https://openalex.org/C2780394083', 'wikidata': 'https://www.wikidata.org/wiki/Q539568', 'display_name': 'Angiogenesis', 'level': 2, 'score': 0.7617134}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.49971414}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.4850301}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.47030088}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.46843466}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.46276656}, {'id': 'https://openalex.org/C7806222', 'wikidata': 'https://www.wikidata.org/wiki/Q5014889', 'display_name': 'CXCL5', 'level': 4, 'score': 0.4283609}, {'id': 'https://openalex.org/C68324877', 'wikidata': 'https://www.wikidata.org/wiki/Q421859', 'display_name': 'Interleukin 8', 'level': 3, 'score': 0.41900635}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.34265488}, {'id': 'https://openalex.org/C2776090121', 'wikidata': 'https://www.wikidata.org/wiki/Q193529', 'display_name': 'T cell', 'level': 3, 'score': 0.30953205}, {'id': 'https://openalex.org/C2778690821', 'wikidata': 'https://www.wikidata.org/wiki/Q212354', 'display_name': 'Cytokine', 'level': 2, 'score': 0.27617285}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.2706939}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.18418771}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.08210996}, {'id': 'https://openalex.org/C79484868', 'wikidata': 'https://www.wikidata.org/wiki/Q5971673', 'display_name': 'IL-2 receptor', 'level': 4, 'score': 0.07201567}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.058676988}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D016922', 'descriptor_name': 'Cellular Senescence', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D018946', 'descriptor_name': 'Chemokine CCL5', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D004847', 'descriptor_name': 'Epithelial Cells', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D018919', 'descriptor_name': 'Neovascularization, Physiologic', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D011467', 'descriptor_name': 'Prostate', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D000367', 'descriptor_name': 'Age Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002465', 'descriptor_name': 'Cell Movement', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002465', 'descriptor_name': 'Cell Movement', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D016922', 'descriptor_name': 'Cellular Senescence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018946', 'descriptor_name': 'Chemokine CCL5', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D018946', 'descriptor_name': 'Chemokine CCL5', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017077', 'descriptor_name': 'Culture Media, Conditioned', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D017077', 'descriptor_name': 'Culture Media, Conditioned', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004847', 'descriptor_name': 'Epithelial Cells', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D004847', 'descriptor_name': 'Epithelial Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020869', 'descriptor_name': 'Gene Expression Profiling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018919', 'descriptor_name': 'Neovascularization, Physiologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020411', 'descriptor_name': 'Oligonucleotide Array Sequence Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011467', 'descriptor_name': 'Prostate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011470', 'descriptor_name': 'Prostatic Hyperplasia', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011470', 'descriptor_name': 'Prostatic Hyperplasia', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D011470', 'descriptor_name': 'Prostatic Hyperplasia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/jcp.21776', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S43643205', 'display_name': 'Journal of Cellular Physiology', 'issn_l': '0021-9541', 'issn': ['0021-9541', '1097-4652'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2846281', 'pdf_url': 'https://europepmc.org/articles/pmc2846281?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846281', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19360811', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2846281', 'pdf_url': 'https://europepmc.org/articles/pmc2846281?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 55, 'referenced_works': ['https://openalex.org/W1561228697', 'https://openalex.org/W1581259003', 'https://openalex.org/W1593300855', 'https://openalex.org/W1862673433', 'https://openalex.org/W1965179151', 'https://openalex.org/W1974557172', 'https://openalex.org/W1975069346', 'https://openalex.org/W1975555969', 'https://openalex.org/W1978401724', 'https://openalex.org/W1981147501', 'https://openalex.org/W1982673084', 'https://openalex.org/W2000556101', 'https://openalex.org/W2006961352', 'https://openalex.org/W2009270104', 'https://openalex.org/W2010146889', 'https://openalex.org/W2024209230', 'https://openalex.org/W2031951436', 'https://openalex.org/W2034320146', 'https://openalex.org/W2037023229', 'https://openalex.org/W2050344387', 'https://openalex.org/W2052413295', 'https://openalex.org/W2053831799', 'https://openalex.org/W2060979010', 'https://openalex.org/W2067863474', 'https://openalex.org/W2070338369', 'https://openalex.org/W2070885297', 'https://openalex.org/W2075600855', 'https://openalex.org/W2077665257', 'https://openalex.org/W2088188305', 'https://openalex.org/W2090575954', 'https://openalex.org/W2090788158', 'https://openalex.org/W2091369486', 'https://openalex.org/W2091762807', 'https://openalex.org/W2092243672', 'https://openalex.org/W2097125354', 'https://openalex.org/W2098009765', 'https://openalex.org/W2100065850', 'https://openalex.org/W2104908670', 'https://openalex.org/W2112334521', 'https://openalex.org/W2117345526', 'https://openalex.org/W2117869125', 'https://openalex.org/W2119930698', 'https://openalex.org/W2123684807', 'https://openalex.org/W2135829603', 'https://openalex.org/W2138788396', 'https://openalex.org/W2141720111', 'https://openalex.org/W2142480001', 'https://openalex.org/W2147820545', 'https://openalex.org/W2148120568', 'https://openalex.org/W2158831697', 'https://openalex.org/W2163303508', 'https://openalex.org/W2163525357', 'https://openalex.org/W2169612578', 'https://openalex.org/W2169664148', 'https://openalex.org/W92378175'], 'related_works': ['https://openalex.org/W4243260974', 'https://openalex.org/W4225259124', 'https://openalex.org/W2354626317', 'https://openalex.org/W2236876228', 'https://openalex.org/W2167993798', 'https://openalex.org/W2123359985', 'https://openalex.org/W2112981710', 'https://openalex.org/W2063488613', 'https://openalex.org/W1992840590', 'https://openalex.org/W1972928492'], 'abstract_inverted_index': {'There': [0], 'is': [1, 151], 'increased': [2, 92, 129], 'interest': [3], 'in': [4, 90, 106, 128, 138], 'the': [5, 67, 82, 107, 139], 'effects': [6], 'of': [7, 44, 74, 94, 110, 122, 141], 'secretory': [8], 'products': [9], 'from': [10, 28], 'aged': [11, 30, 157], 'cells': [12, 124, 158], 'on': [13], 'promoting': [14], 'both': [15], 'benign': [16, 45], 'and': [17, 37, 60, 77, 104, 131, 163], 'malignant': [18], 'cell': [19], 'growth.': [20], 'We': [21, 64], 'identified': [22, 56], 'a': [23, 152], 'human': [24], 'fibroblast': [25, 69], 'line,': [26], 'AG04382,': [27], 'an': [29], 'donor': [31], 'that': [32, 66, 113, 143, 149, 159], 'naturally': [33], 'demonstrated': [34], 'senescence-associated': [35], 'features': [36], 'whose': [38], 'conditioned': [39, 86, 108], 'media': [40, 87, 109], 'significantly': [41, 117], 'induced': [42], 'proliferation': [43, 130], 'prostatic': [46], 'hyperplasia': [47], '(BPH1)': [48], 'cells.': [49], 'Candidate': [50], 'cytokines': [51], 'mediating': [52], 'this': [53], 'effect': [54], 'were': [55], 'with': [57, 125], 'protein': [58], 'arrays': [59], 'validated': [61], 'by': [62, 156], 'ELISA.': [63], 'found': [65], 'AG04382': [68, 111], 'line': [70], 'secreted': [71, 155], 'high': [72], 'levels': [73], 'CXCL5,': [75, 102], 'CCL5,': [76, 103], 'CCL2,': [78], 'but': [79], 'relative': [80], 'to': [81, 118], 'other': [83], 'lines,': [84], 'its': [85, 91], 'was': [88], 'unique': [89], 'expression': [93, 140], 'CCL5.': [95], 'Blocking': [96], 'studies': [97], 'using': [98], 'specific': [99], 'antibodies': [100], 'against': [101], 'CCL2': [105], 'showed': [112], 'only': [114], 'CCL5': [115, 150], 'contributed': [116], 'BPH1': [119, 123], 'proliferation.': [120], 'Stimulation': [121], 'rhuCCL5': [126], 'resulted': [127], 'migration,': [132], 'as': [133, 135], 'well': [134], 'significant': [136], 'changes': [137], 'genes': [142], 'influence': [144], 'angiogenesis.': [145, 165], 'These': [146], 'data': [147], 'suggest': [148], 'candidate': [153], 'chemokine': [154], 'promotes': [160], 'prostate': [161], 'growth': [162], 'regulates': [164]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2042531378', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-25T09:21:49.004864', 'created_date': '2016-06-24'}