Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2042433863', 'doi': 'https://doi.org/10.1016/j.cell.2010.01.022', 'title': 'Pattern Recognition Receptors and Inflammation', 'display_name': 'Pattern Recognition Receptors and Inflammation', 'publication_year': 2010, 'publication_date': '2010-03-01', 'ids': {'openalex': 'https://openalex.org/W2042433863', 'doi': 'https://doi.org/10.1016/j.cell.2010.01.022', 'mag': '2042433863', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20303872'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.cell.2010.01.022', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S110447773', 'display_name': 'Cell', 'issn_l': '0092-8674', 'issn': ['0092-8674', '1097-4172'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://doi.org/10.1016/j.cell.2010.01.022', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5056230564', 'display_name': 'Osamu Takeuchi', 'orcid': 'https://orcid.org/0000-0002-1260-6232'}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Osamu Takeuchi', 'raw_affiliation_strings': ['Laboratory of Host Defense, WPI Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan', 'Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Host Defense, WPI Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan', 'institution_ids': ['https://openalex.org/I98285908']}, {'raw_affiliation_string': 'Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5018553332', 'display_name': 'Shizuo Akira', 'orcid': 'https://orcid.org/0000-0001-7602-9617'}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shizuo Akira', 'raw_affiliation_strings': ['Laboratory of Host Defense, WPI Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan', 'Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan'], 'affiliations': [{'raw_affiliation_string': 'Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan', 'institution_ids': ['https://openalex.org/I98285908']}, {'raw_affiliation_string': 'Laboratory of Host Defense, WPI Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan', 'institution_ids': ['https://openalex.org/I98285908']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 10100, 'currency': 'USD', 'value_usd': 10100, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 38.663, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 7790, 'citation_normalized_percentile': {'value': 0.998875, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '140', 'issue': '6', 'first_page': '805', 'last_page': '820'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11668', 'display_name': 'interferon and immune responses', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11668', 'display_name': 'interferon and immune responses', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11078', 'display_name': 'Inflammasome and immune disorders', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/c-type-lectin', 'display_name': 'C-type lectin', 'score': 0.47554776}, {'id': 'https://openalex.org/keywords/damp', 'display_name': 'Damp', 'score': 0.46018276}, {'id': 'https://openalex.org/keywords/immune-receptor', 'display_name': 'Immune receptor', 'score': 0.4475407}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.87013394}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.7735044}, {'id': 'https://openalex.org/C111289621', 'wikidata': 'https://www.wikidata.org/wiki/Q418772', 'display_name': 'Pattern recognition receptor', 'level': 4, 'score': 0.7298677}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.59980613}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.59753746}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5656432}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.5451602}, {'id': 'https://openalex.org/C136449434', 'wikidata': 'https://www.wikidata.org/wiki/Q428253', 'display_name': 'Innate immune system', 'level': 3, 'score': 0.5417237}, {'id': 'https://openalex.org/C2780130043', 'wikidata': 'https://www.wikidata.org/wiki/Q192360', 'display_name': 'Autoimmunity', 'level': 3, 'score': 0.538326}, {'id': 'https://openalex.org/C55851684', 'wikidata': 'https://www.wikidata.org/wiki/Q518390', 'display_name': 'Nod', 'level': 3, 'score': 0.4798762}, {'id': 'https://openalex.org/C106257327', 'wikidata': 'https://www.wikidata.org/wiki/Q24788214', 'display_name': 'C-type lectin', 'level': 3, 'score': 0.47554776}, {'id': 'https://openalex.org/C2777482401', 'wikidata': 'https://www.wikidata.org/wiki/Q469057', 'display_name': 'Damp', 'level': 2, 'score': 0.46018276}, {'id': 'https://openalex.org/C103474210', 'wikidata': 'https://www.wikidata.org/wiki/Q142851', 'display_name': 'Immune receptor', 'level': 3, 'score': 0.4475407}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.29864037}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.120033085}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.11171284}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C153294291', 'wikidata': 'https://www.wikidata.org/wiki/Q25261', 'display_name': 'Meteorology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D051192', 'descriptor_name': 'Receptors, Pattern Recognition', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003593', 'descriptor_name': 'Cytoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003593', 'descriptor_name': 'Cytoplasm', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007239', 'descriptor_name': 'Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007239', 'descriptor_name': 'Infections', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051192', 'descriptor_name': 'Receptors, Pattern Recognition', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051193', 'descriptor_name': 'Toll-Like Receptors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051193', 'descriptor_name': 'Toll-Like Receptors', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.cell.2010.01.022', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S110447773', 'display_name': 'Cell', 'issn_l': '0092-8674', 'issn': ['0092-8674', '1097-4172'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20303872', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.cell.2010.01.022', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S110447773', 'display_name': 'Cell', 'issn_l': '0092-8674', 'issn': ['0092-8674', '1097-4172'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.72, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [{'funder': 'https://openalex.org/F4320320912', 'funder_display_name': 'Ministry of Education, Culture, Sports, Science and Technology', 'award_id': None}, {'funder': 'https://openalex.org/F4320332161', 'funder_display_name': 'National Institutes of Health', 'award_id': 'P01 AI070167'}], 'datasets': [], 'versions': [], 'referenced_works_count': 145, 'referenced_works': ['https://openalex.org/W1503306485', 'https://openalex.org/W1539659593', 'https://openalex.org/W1569574024', 'https://openalex.org/W1579696447', 'https://openalex.org/W1591714343', 'https://openalex.org/W1894719160', 'https://openalex.org/W1963751749', 'https://openalex.org/W1968178474', 'https://openalex.org/W1969354039', 'https://openalex.org/W1969601023', 'https://openalex.org/W1969776705', 'https://openalex.org/W1969913081', 'https://openalex.org/W1970154782', 'https://openalex.org/W1975215291', 'https://openalex.org/W1975359970', 'https://openalex.org/W1980494339', 'https://openalex.org/W1986303112', 'https://openalex.org/W1987241739', 'https://openalex.org/W1987410025', 'https://openalex.org/W1993832002', 'https://openalex.org/W1995744610', 'https://openalex.org/W1999064607', 'https://openalex.org/W1999746344', 'https://openalex.org/W2004608668', 'https://openalex.org/W2005884645', 'https://openalex.org/W2007222211', 'https://openalex.org/W2008969317', 'https://openalex.org/W2009127910', 'https://openalex.org/W2009708031', 'https://openalex.org/W2011265690', 'https://openalex.org/W2012005937', 'https://openalex.org/W2016194523', 'https://openalex.org/W2017515700', 'https://openalex.org/W2017760549', 'https://openalex.org/W2018653121', 'https://openalex.org/W2020040634', 'https://openalex.org/W2026563152', 'https://openalex.org/W2027443955', 'https://openalex.org/W2028575270', 'https://openalex.org/W2028792773', 'https://openalex.org/W2031084334', 'https://openalex.org/W2031182394', 'https://openalex.org/W2032758279', 'https://openalex.org/W2032948492', 'https://openalex.org/W2033106764', 'https://openalex.org/W2034708798', 'https://openalex.org/W2036584139', 'https://openalex.org/W2040459416', 'https://openalex.org/W2041308303', 'https://openalex.org/W2042436346', 'https://openalex.org/W2043801813', 'https://openalex.org/W2043959346', 'https://openalex.org/W2048067575', 'https://openalex.org/W2048992607', 'https://openalex.org/W2058229730', 'https://openalex.org/W2060004514', 'https://openalex.org/W2060098032', 'https://openalex.org/W2060383679', 'https://openalex.org/W2060441844', 'https://openalex.org/W2060681628', 'https://openalex.org/W2061203855', 'https://openalex.org/W2062490839', 'https://openalex.org/W2064741210', 'https://openalex.org/W2065276143', 'https://openalex.org/W2065429310', 'https://openalex.org/W2065864183', 'https://openalex.org/W2066203385', 'https://openalex.org/W2066728093', 'https://openalex.org/W2067678108', 'https://openalex.org/W2067706259', 'https://openalex.org/W2068551986', 'https://openalex.org/W2071162967', 'https://openalex.org/W2071670416', 'https://openalex.org/W2074036892', 'https://openalex.org/W2074472721', 'https://openalex.org/W2074795280', 'https://openalex.org/W2075860675', 'https://openalex.org/W2076690763', 'https://openalex.org/W2077648685', 'https://openalex.org/W2080399344', 'https://openalex.org/W2083974181', 'https://openalex.org/W2084482466', 'https://openalex.org/W2084951281', 'https://openalex.org/W2089276791', 'https://openalex.org/W2089712328', 'https://openalex.org/W2090179551', 'https://openalex.org/W2091479071', 'https://openalex.org/W2091596699', 'https://openalex.org/W2091906420', 'https://openalex.org/W2094605832', 'https://openalex.org/W2096853390', 'https://openalex.org/W2099029060', 'https://openalex.org/W2100446659', 'https://openalex.org/W2100665873', 'https://openalex.org/W2100706488', 'https://openalex.org/W2102403552', 'https://openalex.org/W2102572106', 'https://openalex.org/W2102791251', 'https://openalex.org/W2103500013', 'https://openalex.org/W2105221079', 'https://openalex.org/W2107444074', 'https://openalex.org/W2109231206', 'https://openalex.org/W2110768898', 'https://openalex.org/W2111200149', 'https://openalex.org/W2111846773', 'https://openalex.org/W2111922856', 'https://openalex.org/W2113295282', 'https://openalex.org/W2113576692', 'https://openalex.org/W2116803339', 'https://openalex.org/W2118926211', 'https://openalex.org/W2119492463', 'https://openalex.org/W2123879591', 'https://openalex.org/W2125566625', 'https://openalex.org/W2125945390', 'https://openalex.org/W2126887217', 'https://openalex.org/W2127934565', 'https://openalex.org/W2129359803', 'https://openalex.org/W2129374849', 'https://openalex.org/W2130775443', 'https://openalex.org/W2132482634', 'https://openalex.org/W2133006561', 'https://openalex.org/W2133972984', 'https://openalex.org/W2134106169', 'https://openalex.org/W2134505828', 'https://openalex.org/W2136329789', 'https://openalex.org/W2137540618', 'https://openalex.org/W2137881107', 'https://openalex.org/W2138677670', 'https://openalex.org/W2140700343', 'https://openalex.org/W2140815975', 'https://openalex.org/W2142162924', 'https://openalex.org/W2145221987', 'https://openalex.org/W2148214390', 'https://openalex.org/W2148985310', 'https://openalex.org/W2150058561', 'https://openalex.org/W2150736048', 'https://openalex.org/W2153280179', 'https://openalex.org/W2156613610', 'https://openalex.org/W2159685069', 'https://openalex.org/W2161577497', 'https://openalex.org/W2163278196', 'https://openalex.org/W2165748936', 'https://openalex.org/W2167317609', 'https://openalex.org/W2169211336', 'https://openalex.org/W2288617339'], 'related_works': ['https://openalex.org/W3204085801', 'https://openalex.org/W3123567612', 'https://openalex.org/W2976957583', 'https://openalex.org/W2962384148', 'https://openalex.org/W2480962382', 'https://openalex.org/W2371493666', 'https://openalex.org/W2353554174', 'https://openalex.org/W2096097730', 'https://openalex.org/W2077594489', 'https://openalex.org/W2072449362'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2042433863', 'counts_by_year': [{'year': 2024, 'cited_by_count': 609}, {'year': 2023, 'cited_by_count': 663}, {'year': 2022, 'cited_by_count': 777}, {'year': 2021, 'cited_by_count': 786}, {'year': 2020, 'cited_by_count': 644}, {'year': 2019, 'cited_by_count': 545}, {'year': 2018, 'cited_by_count': 504}, {'year': 2017, 'cited_by_count': 519}, {'year': 2016, 'cited_by_count': 499}, {'year': 2015, 'cited_by_count': 444}, {'year': 2014, 'cited_by_count': 522}, {'year': 2013, 'cited_by_count': 458}, {'year': 2012, 'cited_by_count': 365}], 'updated_date': '2025-01-08T05:18:31.393962', 'created_date': '2016-06-24'}