Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2042071353', 'doi': 'https://doi.org/10.1016/j.bbamcr.2013.06.004', 'title': 'The endoplasmic reticulum and junctional membrane communication during calcium signaling', 'display_name': 'The endoplasmic reticulum and junctional membrane communication during calcium signaling', 'publication_year': 2013, 'publication_date': '2013-11-01', 'ids': {'openalex': 'https://openalex.org/W2042071353', 'doi': 'https://doi.org/10.1016/j.bbamcr.2013.06.004', 'mag': '2042071353', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23770047'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbamcr.2013.06.004', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210226410', 'display_name': 'Biochimica et Biophysica Acta (BBA) - Molecular Cell Research', 'issn_l': '0167-4889', 'issn': ['0167-4889', '1879-2596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5062934053', 'display_name': 'Andy K.M. Lam', 'orcid': 'https://orcid.org/0000-0002-2983-3044'}, 'institutions': [{'id': 'https://openalex.org/I40120149', 'display_name': 'University of Oxford', 'ror': 'https://ror.org/052gg0110', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I40120149']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Andy K.M. Lam', 'raw_affiliation_strings': ['Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK', 'institution_ids': ['https://openalex.org/I40120149']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5026573711', 'display_name': 'Antony Galione', 'orcid': 'https://orcid.org/0000-0002-4132-7646'}, 'institutions': [{'id': 'https://openalex.org/I40120149', 'display_name': 'University of Oxford', 'ror': 'https://ror.org/052gg0110', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I40120149']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Antony Galione', 'raw_affiliation_strings': ['Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK', 'institution_ids': ['https://openalex.org/I40120149']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3380, 'currency': 'USD', 'value_usd': 3380, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.51, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 110, 'citation_normalized_percentile': {'value': 0.594828, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '1833', 'issue': '11', 'first_page': '2542', 'last_page': '2559'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T13415', 'display_name': 'Lysosomal Calcium Signaling in Physiology and Pathology', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1314', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T13415', 'display_name': 'Lysosomal Calcium Signaling in Physiology and Pathology', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1314', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10617', 'display_name': 'Mechanisms of Intracellular Membrane Trafficking', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10493', 'display_name': 'Molecular Mechanisms of Ion Channels Regulation', 'score': 0.994, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/calcium-signaling', 'display_name': 'Calcium signaling', 'score': 0.6784809}, {'id': 'https://openalex.org/keywords/membrane-contact-site', 'display_name': 'Membrane contact site', 'score': 0.63941485}, {'id': 'https://openalex.org/keywords/organelle', 'display_name': 'Organelle', 'score': 0.57075894}, {'id': 'https://openalex.org/keywords/cell-signaling', 'display_name': 'Cell Signaling', 'score': 0.511399}], 'concepts': [{'id': 'https://openalex.org/C158617107', 'wikidata': 'https://www.wikidata.org/wiki/Q79927', 'display_name': 'Endoplasmic reticulum', 'level': 2, 'score': 0.969327}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.7822719}, {'id': 'https://openalex.org/C162740809', 'wikidata': 'https://www.wikidata.org/wiki/Q15334560', 'display_name': 'STIM1', 'level': 3, 'score': 0.7643453}, {'id': 'https://openalex.org/C201571599', 'wikidata': 'https://www.wikidata.org/wiki/Q5018840', 'display_name': 'Calcium signaling', 'level': 3, 'score': 0.6784809}, {'id': 'https://openalex.org/C88020867', 'wikidata': 'https://www.wikidata.org/wiki/Q6815123', 'display_name': 'Membrane contact site', 'level': 5, 'score': 0.63941485}, {'id': 'https://openalex.org/C168240541', 'wikidata': 'https://www.wikidata.org/wiki/Q45948', 'display_name': 'Organelle', 'level': 2, 'score': 0.57075894}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.46370962}, {'id': 'https://openalex.org/C6492254', 'wikidata': 'https://www.wikidata.org/wiki/Q84230', 'display_name': 'Secretory pathway', 'level': 4, 'score': 0.43255395}, {'id': 'https://openalex.org/C190062978', 'wikidata': 'https://www.wikidata.org/wiki/Q79899', 'display_name': 'Cytoplasm', 'level': 2, 'score': 0.42728493}, {'id': 'https://openalex.org/C119062480', 'wikidata': 'https://www.wikidata.org/wiki/Q83181', 'display_name': 'Golgi apparatus', 'level': 3, 'score': 0.42558262}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.37424472}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.34165287}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.29936737}, {'id': 'https://openalex.org/C144647389', 'wikidata': 'https://www.wikidata.org/wiki/Q423042', 'display_name': 'Membrane protein', 'level': 3, 'score': 0.2719226}, {'id': 'https://openalex.org/C41625074', 'wikidata': 'https://www.wikidata.org/wiki/Q176088', 'display_name': 'Membrane', 'level': 2, 'score': 0.22330064}, {'id': 'https://openalex.org/C161200384', 'wikidata': 'https://www.wikidata.org/wiki/Q1757382', 'display_name': 'Integral membrane protein', 'level': 4, 'score': 0.113850534}], 'mesh': [{'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015220', 'descriptor_name': 'Calcium Channels', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D020013', 'descriptor_name': 'Calcium Signaling', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D004721', 'descriptor_name': 'Endoplasmic Reticulum', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015220', 'descriptor_name': 'Calcium Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020013', 'descriptor_name': 'Calcium Signaling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004721', 'descriptor_name': 'Endoplasmic Reticulum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbamcr.2013.06.004', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210226410', 'display_name': 'Biochimica et Biophysica Acta (BBA) - Molecular Cell Research', 'issn_l': '0167-4889', 'issn': ['0167-4889', '1879-2596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23770047', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 306, 'referenced_works': ['https://openalex.org/W1494114085', 'https://openalex.org/W1520395487', 'https://openalex.org/W1524417563', 'https://openalex.org/W1528977425', 'https://openalex.org/W1540222357', 'https://openalex.org/W1542263802', 'https://openalex.org/W1571164133', 'https://openalex.org/W1575995900', 'https://openalex.org/W1580746914', 'https://openalex.org/W1598081743', 'https://openalex.org/W1599277155', 'https://openalex.org/W1606220682', 'https://openalex.org/W1615545200', 'https://openalex.org/W1782667879', 'https://openalex.org/W1853732393', 'https://openalex.org/W1856053518', 'https://openalex.org/W1900339045', 'https://openalex.org/W1929385394', 'https://openalex.org/W1935060748', 'https://openalex.org/W1952906612', 'https://openalex.org/W1953311373', 'https://openalex.org/W1963791094', 'https://openalex.org/W1964549513', 'https://openalex.org/W1965021019', 'https://openalex.org/W1965590635', 'https://openalex.org/W1965790765', 'https://openalex.org/W1965893090', 'https://openalex.org/W1966467373', 'https://openalex.org/W1967626349', 'https://openalex.org/W1968257316', 'https://openalex.org/W1969637387', 'https://openalex.org/W1969709153', 'https://openalex.org/W1972080672', 'https://openalex.org/W1974507976', 'https://openalex.org/W1975645575', 'https://openalex.org/W1975700762', 'https://openalex.org/W1975832881', 'https://openalex.org/W1975992025', 'https://openalex.org/W1976134600', 'https://openalex.org/W1976621077', 'https://openalex.org/W1976913583', 'https://openalex.org/W1977201959', 'https://openalex.org/W1977413050', 'https://openalex.org/W1977703065', 'https://openalex.org/W1978260512', 'https://openalex.org/W1978593035', 'https://openalex.org/W1980610652', 'https://openalex.org/W1980939512', 'https://openalex.org/W1981049765', 'https://openalex.org/W1981582810', 'https://openalex.org/W1982528213', 'https://openalex.org/W1983181941', 'https://openalex.org/W1983188620', 'https://openalex.org/W1984638411', 'https://openalex.org/W1985313695', 'https://openalex.org/W1985730861', 'https://openalex.org/W1985785210', 'https://openalex.org/W1986213783', 'https://openalex.org/W1988252217', 'https://openalex.org/W1988421541', 'https://openalex.org/W1990076574', 'https://openalex.org/W1990441231', 'https://openalex.org/W1990567099', 'https://openalex.org/W1991055482', 'https://openalex.org/W1991865867', 'https://openalex.org/W1993228729', 'https://openalex.org/W1993401680', 'https://openalex.org/W1993480617', 'https://openalex.org/W1994786455', 'https://openalex.org/W1995540148', 'https://openalex.org/W1995873775', 'https://openalex.org/W1997018082', 'https://openalex.org/W1997112574', 'https://openalex.org/W1997778815', 'https://openalex.org/W1997816574', 'https://openalex.org/W1999741914', 'https://openalex.org/W2000665911', 'https://openalex.org/W2000683352', 'https://openalex.org/W2001917660', 'https://openalex.org/W2002791298', 'https://openalex.org/W2003197964', 'https://openalex.org/W2004540956', 'https://openalex.org/W2005216847', 'https://openalex.org/W2005302551', 'https://openalex.org/W2005641938', 'https://openalex.org/W2007513923', 'https://openalex.org/W2007781466', 'https://openalex.org/W2008245136', 'https://openalex.org/W2008363564', 'https://openalex.org/W2009301053', 'https://openalex.org/W2010572143', 'https://openalex.org/W2011432266', 'https://openalex.org/W2011786631', 'https://openalex.org/W2011921884', 'https://openalex.org/W2012233526', 'https://openalex.org/W2012335235', 'https://openalex.org/W2012751980', 'https://openalex.org/W2013003557', 'https://openalex.org/W2013798123', 'https://openalex.org/W2014985826', 'https://openalex.org/W2014993252', 'https://openalex.org/W2015536770', 'https://openalex.org/W2016121717', 'https://openalex.org/W2016479661', 'https://openalex.org/W2016944692', 'https://openalex.org/W2017073927', 'https://openalex.org/W2017173867', 'https://openalex.org/W2017245381', 'https://openalex.org/W2017281114', 'https://openalex.org/W2019023589', 'https://openalex.org/W2019079031', 'https://openalex.org/W2020325237', 'https://openalex.org/W2020372983', 'https://openalex.org/W2020536777', 'https://openalex.org/W2021069369', 'https://openalex.org/W2023024494', 'https://openalex.org/W2024969865', 'https://openalex.org/W2025695820', 'https://openalex.org/W2026452617', 'https://openalex.org/W2026571586', 'https://openalex.org/W2028023732', 'https://openalex.org/W2030650261', 'https://openalex.org/W2031790758', 'https://openalex.org/W2032362466', 'https://openalex.org/W2032781637', 'https://openalex.org/W2032816757', 'https://openalex.org/W2033113702', 'https://openalex.org/W2034507898', 'https://openalex.org/W2035348154', 'https://openalex.org/W2035920388', 'https://openalex.org/W2036557271', 'https://openalex.org/W2036701273', 'https://openalex.org/W2036997353', 'https://openalex.org/W2038626940', 'https://openalex.org/W2042892520', 'https://openalex.org/W2044173086', 'https://openalex.org/W2044541783', 'https://openalex.org/W2045164997', 'https://openalex.org/W2045583936', 'https://openalex.org/W2046196975', 'https://openalex.org/W2046369033', 'https://openalex.org/W2047112668', 'https://openalex.org/W2048221764', 'https://openalex.org/W2048465199', 'https://openalex.org/W2048682543', 'https://openalex.org/W2049529068', 'https://openalex.org/W2049940479', 'https://openalex.org/W2050824263', 'https://openalex.org/W2051404222', 'https://openalex.org/W2052304001', 'https://openalex.org/W2052471341', 'https://openalex.org/W2052739933', 'https://openalex.org/W2052964194', 'https://openalex.org/W2056145463', 'https://openalex.org/W2056633265', 'https://openalex.org/W2057252925', 'https://openalex.org/W2057264167', 'https://openalex.org/W2057872722', 'https://openalex.org/W2058449890', 'https://openalex.org/W2060802834', 'https://openalex.org/W2061436416', 'https://openalex.org/W2063041590', 'https://openalex.org/W2063081959', 'https://openalex.org/W2065054453', 'https://openalex.org/W2065368005', 'https://openalex.org/W2065569764', 'https://openalex.org/W2065771385', 'https://openalex.org/W2065773869', 'https://openalex.org/W2066585188', 'https://openalex.org/W2066963386', 'https://openalex.org/W2067841051', 'https://openalex.org/W2069274491', 'https://openalex.org/W2070832223', 'https://openalex.org/W2072266307', 'https://openalex.org/W2073095545', 'https://openalex.org/W2073308483', 'https://openalex.org/W2073327841', 'https://openalex.org/W2073679788', 'https://openalex.org/W2073706613', 'https://openalex.org/W2074085303', 'https://openalex.org/W2074132933', 'https://openalex.org/W2075094914', 'https://openalex.org/W2076531123', 'https://openalex.org/W2076698517', 'https://openalex.org/W2078391920', 'https://openalex.org/W2079071687', 'https://openalex.org/W2080015061', 'https://openalex.org/W2080163146', 'https://openalex.org/W2081397479', 'https://openalex.org/W2081959931', 'https://openalex.org/W2082089816', 'https://openalex.org/W2082625926', 'https://openalex.org/W2082849134', 'https://openalex.org/W2085111073', 'https://openalex.org/W2085113308', 'https://openalex.org/W2085474187', 'https://openalex.org/W2086698861', 'https://openalex.org/W2087739792', 'https://openalex.org/W2088093088', 'https://openalex.org/W2088499993', 'https://openalex.org/W2088960324', 'https://openalex.org/W2090240729', 'https://openalex.org/W2090362748', 'https://openalex.org/W2090706449', 'https://openalex.org/W2091300408', 'https://openalex.org/W2093364468', 'https://openalex.org/W2093439904', 'https://openalex.org/W2094629035', 'https://openalex.org/W2095152173', 'https://openalex.org/W2095201918', 'https://openalex.org/W2095402256', 'https://openalex.org/W2096183879', 'https://openalex.org/W2096199252', 'https://openalex.org/W2096579721', 'https://openalex.org/W2097265484', 'https://openalex.org/W2098329073', 'https://openalex.org/W2100310965', 'https://openalex.org/W2101586949', 'https://openalex.org/W2101765077', 'https://openalex.org/W2108183974', 'https://openalex.org/W2108411628', 'https://openalex.org/W2108578589', 'https://openalex.org/W2112045725', 'https://openalex.org/W2112583647', 'https://openalex.org/W2112794298', 'https://openalex.org/W2114228694', 'https://openalex.org/W2114996039', 'https://openalex.org/W2115021528', 'https://openalex.org/W2115900546', 'https://openalex.org/W2116635624', 'https://openalex.org/W2118810404', 'https://openalex.org/W2118988881', 'https://openalex.org/W2121330845', 'https://openalex.org/W2121556516', 'https://openalex.org/W2122005870', 'https://openalex.org/W2122025785', 'https://openalex.org/W2123384023', 'https://openalex.org/W2123466564', 'https://openalex.org/W2126948267', 'https://openalex.org/W2127063807', 'https://openalex.org/W2127088485', 'https://openalex.org/W2128484647', 'https://openalex.org/W2130233190', 'https://openalex.org/W2131387907', 'https://openalex.org/W2132320808', 'https://openalex.org/W2133603157', 'https://openalex.org/W2134791820', 'https://openalex.org/W2136225082', 'https://openalex.org/W2137283585', 'https://openalex.org/W2137508826', 'https://openalex.org/W2137884233', 'https://openalex.org/W2138786573', 'https://openalex.org/W2138958648', 'https://openalex.org/W2139625864', 'https://openalex.org/W2139989763', 'https://openalex.org/W2140313980', 'https://openalex.org/W2140955594', 'https://openalex.org/W2141260882', 'https://openalex.org/W2141385342', 'https://openalex.org/W2142240313', 'https://openalex.org/W2143695671', 'https://openalex.org/W2145686156', 'https://openalex.org/W2146289785', 'https://openalex.org/W2146341872', 'https://openalex.org/W2146447679', 'https://openalex.org/W2146949990', 'https://openalex.org/W2148185042', 'https://openalex.org/W2149352571', 'https://openalex.org/W2150832037', 'https://openalex.org/W2150991652', 'https://openalex.org/W2153698618', 'https://openalex.org/W2155147247', 'https://openalex.org/W2155842024', 'https://openalex.org/W2156083006', 'https://openalex.org/W2156675315', 'https://openalex.org/W2157073047', 'https://openalex.org/W2157869491', 'https://openalex.org/W2160975493', 'https://openalex.org/W2161440135', 'https://openalex.org/W2161549748', 'https://openalex.org/W2163789582', 'https://openalex.org/W2165292955', 'https://openalex.org/W2165573061', 'https://openalex.org/W2166432730', 'https://openalex.org/W2168921260', 'https://openalex.org/W2168983594', 'https://openalex.org/W2169410461', 'https://openalex.org/W2169635583', 'https://openalex.org/W2169854908', 'https://openalex.org/W2170274797', 'https://openalex.org/W2170376656', 'https://openalex.org/W2172267807', 'https://openalex.org/W2187420146', 'https://openalex.org/W2318239700', 'https://openalex.org/W2396028691', 'https://openalex.org/W2396888550', 'https://openalex.org/W2401018933', 'https://openalex.org/W2403713465', 'https://openalex.org/W2413549617', 'https://openalex.org/W2853874477', 'https://openalex.org/W2971700467', 'https://openalex.org/W2995106832', 'https://openalex.org/W4211132321', 'https://openalex.org/W4234290491', 'https://openalex.org/W4249424055', 'https://openalex.org/W4285719527'], 'related_works': ['https://openalex.org/W4241790563', 'https://openalex.org/W3159607164', 'https://openalex.org/W2416224051', 'https://openalex.org/W2158592428', 'https://openalex.org/W2150351373', 'https://openalex.org/W2105729094', 'https://openalex.org/W2068122493', 'https://openalex.org/W1995405373', 'https://openalex.org/W1975323469', 'https://openalex.org/W1578855781'], 'abstract_inverted_index': {'The': [0, 29], 'endoplasmic': [1, 30, 103, 126, 145, 158, 187, 271], 'reticulum': [2, 104, 127, 146, 159, 188], 'is': [3, 40, 163, 247, 259], 'a': [4, 106, 241, 262], 'major': [5, 66, 75], 'organelle': [6, 49], 'in': [7, 50, 55, 109, 116, 214, 244, 252], 'all': [8], 'eukaryotic': [9, 51], 'cells': [10], 'which': [11, 72, 162], 'performs': [12], 'multiple': [13], 'functions': [14], 'including': [15], 'protein': [16], 'and': [17, 20, 24, 27, 32, 43, 82, 91, 121, 196, 203, 226, 234, 240, 267], 'lipid': [18], 'synthesis': [19], 'sorting,': [21], 'drug': [22], 'metabolism,': [23], 'Ca(2+)': [25, 47, 69, 77, 88, 92, 99, 110, 113, 129, 147, 154, 172, 215, 232], 'storage': [26, 48, 70, 84], 'release.': [28], 'reticulum,': [31, 39], 'its': [33, 117], 'specialized': [34], 'muscle': [35], 'counterpart': [36], 'the': [37, 41, 60, 102, 119, 125, 140, 164, 186, 193, 248], 'sarcoplasmic': [38], 'largest': [42], 'most': [44], 'extensive': [45], 'of': [46, 57, 59, 68, 124, 198, 261, 270], 'cells,': [52], 'often': [53, 249], 'occupying': [54], 'excess': [56], '10%': [58], 'cell': [61], 'volume.': [62], 'There': [63], 'are': [64, 150], 'three': [65], 'components': [67], 'organelles': [71, 199], 'mediate': [73], 'their': [74, 208], 'functions:': [76], 'uptake,': [78], 'mediated': [79, 94], 'by': [80, 86, 95, 153, 180], 'pumps': [81], 'exchangers;': [83], 'enhanced': [85], 'luminal': [87], 'binding': [89], 'proteins,': [90], 'mobilization': [93, 100], 'specific': [96, 136, 175], 'ion': [97], 'channels.': [98], 'from': [101], 'plays': [105], 'central': [107], 'role': [108], 'signaling.': [111], 'Through': [112], 'release': [114, 130, 148], 'channels': [115, 149], 'membrane,': [118], 'pervading': [120], 'plastic': [122], 'structure': [123], 'allows': [128], 'to': [131, 135, 157, 177], 'be': [132, 178], 'rapidly': [133], 'targeted': [134], 'cytoplasmic': [137], 'sites': [138], 'across': [139], 'whole': [141], 'cell.': [142], 'That': [143], 'several': [144], 'also': [151], 'activated': [152], 'itself,': [155], 'contributes': [156], 'membrane': [160, 195], 'excitability': [161], 'principal': [165], 'basis': [166], 'for': [167], 'generating': [168], 'spatio-temporal': [169], 'complex': [170], 'cellular': [171, 219, 223], 'signals,': [173], 'allowing': [174], 'processes': [176, 220, 236], 'regulated': [179], 'this': [181, 245], 'universal': [182], 'messenger.': [183], 'In': [184], 'addition,': [185], 'forms': [189], 'discrete': [190], 'junctions': [191, 230], 'with': [192], 'plasma': [194], 'membranes': [197], 'such': [200, 221], 'as': [201, 222], 'mitochondria': [202], 'lysosomes,': [204], 'forming': [205], 'nanodomains': [206], 'at': [207], 'interfaces': [209], 'that': [210], 'play': [211], 'critical': [212], 'roles': [213], 'signaling': [216], 'during': [217], 'key': [218, 231], 'bioenergetics,': [224], 'apoptosis': [225], 'autophagy.': [227], 'At': [228], 'these': [229, 254], 'transport': [233], 'regulatory': [235], 'come': [237], 'into': [238], 'play,': [239], 'recurring': [242], 'theme': [243], 'review': [246], 'tortuous': [250], 'paths': [251], 'identifying': [253], 'mechanisms': [255], 'unequivocally.': [256], 'This': [257], 'article': [258], 'part': [260], 'Special': [263], 'Issue': [264], 'entitled:': [265], 'Functional': [266], 'structural': [268], 'diversity': [269], 'reticulum.': [272]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2042071353', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 9}, {'year': 2021, 'cited_by_count': 10}, {'year': 2020, 'cited_by_count': 17}, {'year': 2019, 'cited_by_count': 12}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 13}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 12}, {'year': 2014, 'cited_by_count': 12}], 'updated_date': '2024-08-13T09:59:14.689139', 'created_date': '2016-06-24'}