Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2041862716', 'doi': 'https://doi.org/10.1111/j.1349-7006.1996.tb03123.x', 'title': 'Primary Human Fibroblasts Induce Diverse Tumor Invasiveness: Involvement of HGF as an Important Paracrine Factor', 'display_name': 'Primary Human Fibroblasts Induce Diverse Tumor Invasiveness: Involvement of HGF as an Important Paracrine Factor', 'publication_year': 1996, 'publication_date': '1996-11-01', 'ids': {'openalex': 'https://openalex.org/W2041862716', 'doi': 'https://doi.org/10.1111/j.1349-7006.1996.tb03123.x', 'mag': '2041862716', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9045942', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5921007'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1349-7006.1996.tb03123.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1349-7006.1996.tb03123.x', 'source': {'id': 'https://openalex.org/S4210193983', 'display_name': 'Japanese Journal of Cancer Research', 'issn_l': '0910-5050', 'issn': ['0910-5050', '1344-6428', '1876-4673'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1349-7006.1996.tb03123.x', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5001676947', 'display_name': 'Takashi Iwazawa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takashi Iwazawa', 'raw_affiliation_strings': ['Second Department of Surgery, Biomedical Research Center, Osaka University Medical School, Suita.'], 'affiliations': [{'raw_affiliation_string': 'Second Department of Surgery, Biomedical Research Center, Osaka University Medical School, Suita.', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5078221062', 'display_name': 'Hitoshi Shiozaki', 'orcid': 'https://orcid.org/0009-0000-1249-4640'}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hitoshi Shiozaki', 'raw_affiliation_strings': ['Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565'], 'affiliations': [{'raw_affiliation_string': 'Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028284770', 'display_name': 'Yuichiro� Doki', 'orcid': 'https://orcid.org/0000-0001-7346-0209'}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yuichiro Doki', 'raw_affiliation_strings': ['Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565'], 'affiliations': [{'raw_affiliation_string': 'Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004846865', 'display_name': 'Masatoshi Inoue', 'orcid': 'https://orcid.org/0000-0001-5077-0052'}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Masatoshi Inoue', 'raw_affiliation_strings': ['Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565'], 'affiliations': [{'raw_affiliation_string': 'Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067567361', 'display_name': 'Shigeyuki Tamura', 'orcid': 'https://orcid.org/0000-0002-1116-5586'}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shigeyuki Tamura', 'raw_affiliation_strings': ['Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565'], 'affiliations': [{'raw_affiliation_string': 'Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020850265', 'display_name': 'Shigeo Matsui', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shigeo Matsui', 'raw_affiliation_strings': ['Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565'], 'affiliations': [{'raw_affiliation_string': 'Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000660745', 'display_name': 'Takushi Monden', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takushi Monden', 'raw_affiliation_strings': ['Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565'], 'affiliations': [{'raw_affiliation_string': 'Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016499405', 'display_name': 'Kunio Matsumoto', 'orcid': 'https://orcid.org/0000-0002-6532-4482'}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kunio Matsumoto', 'raw_affiliation_strings': ['Department of Biochemistry, Biomedical Research Center, Osaka University Medical School, 2‐2 Yamadaoka, Suita, Osaka 565'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Biomedical Research Center, Osaka University Medical School, 2‐2 Yamadaoka, Suita, Osaka 565', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080102542', 'display_name': 'Toshikazu Nakamura', 'orcid': 'https://orcid.org/0000-0001-8672-0946'}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Toshikazu Nakamura', 'raw_affiliation_strings': ['Department of Biochemistry, Biomedical Research Center, Osaka University Medical School, 2‐2 Yamadaoka, Suita, Osaka 565'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Biomedical Research Center, Osaka University Medical School, 2‐2 Yamadaoka, Suita, Osaka 565', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5037320870', 'display_name': 'Morito Monden', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Morito Monden', 'raw_affiliation_strings': ['Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565'], 'affiliations': [{'raw_affiliation_string': 'Second Department of Surgery, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565', 'institution_ids': ['https://openalex.org/I98285908']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.015, 'has_fulltext': False, 'cited_by_count': 40, 'citation_normalized_percentile': {'value': 0.799023, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '87', 'issue': '11', 'first_page': '1134', 'last_page': '1142'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10966', 'display_name': 'Mechanisms and Treatment of Liver Fibrosis', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2721', 'display_name': 'Hepatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10966', 'display_name': 'Mechanisms and Treatment of Liver Fibrosis', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2721', 'display_name': 'Hepatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12287', 'display_name': 'Fibroblast Growth Factor Signaling Pathway', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10839', 'display_name': 'Pancreatic Islet Dysfunction and Regeneration', 'score': 0.9972, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cancer-associated-fibroblasts', 'display_name': 'Cancer-Associated Fibroblasts', 'score': 0.62599444}, {'id': 'https://openalex.org/keywords/fibroblast-growth-factor', 'display_name': 'Fibroblast Growth Factor', 'score': 0.568989}], 'concepts': [{'id': 'https://openalex.org/C2776996007', 'wikidata': 'https://www.wikidata.org/wiki/Q2399112', 'display_name': 'Hepatocyte growth factor', 'level': 3, 'score': 0.9496319}, {'id': 'https://openalex.org/C7876069', 'wikidata': 'https://www.wikidata.org/wiki/Q14873666', 'display_name': 'Paracrine signalling', 'level': 3, 'score': 0.876348}, {'id': 'https://openalex.org/C2909706936', 'wikidata': 'https://www.wikidata.org/wiki/Q42417562', 'display_name': 'Cancer-Associated Fibroblasts', 'level': 4, 'score': 0.62599444}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.5960433}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.5811554}, {'id': 'https://openalex.org/C2780381497', 'wikidata': 'https://www.wikidata.org/wiki/Q463418', 'display_name': 'Fibroblast', 'level': 3, 'score': 0.5248675}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.52271044}, {'id': 'https://openalex.org/C49039625', 'wikidata': 'https://www.wikidata.org/wiki/Q84230', 'display_name': 'Secretion', 'level': 2, 'score': 0.48710942}, {'id': 'https://openalex.org/C2780467284', 'wikidata': 'https://www.wikidata.org/wiki/Q5005897', 'display_name': 'C-Met', 'level': 4, 'score': 0.46062106}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.4468367}, {'id': 'https://openalex.org/C2776107976', 'wikidata': 'https://www.wikidata.org/wiki/Q1786433', 'display_name': 'Tumor microenvironment', 'level': 3, 'score': 0.3251425}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.29930156}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.24095455}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.22723013}, {'id': 'https://openalex.org/C3020616263', 'wikidata': 'https://www.wikidata.org/wiki/Q1216998', 'display_name': 'Tumor cells', 'level': 2, 'score': 0.19685364}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.058792323}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D015820', 'descriptor_name': 'Cadherins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002450', 'descriptor_name': 'Cell Communication', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D003094', 'descriptor_name': 'Collagen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003470', 'descriptor_name': 'Culture Media', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D017228', 'descriptor_name': 'Hepatocyte Growth Factor', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015151', 'descriptor_name': 'Immunoblotting', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009361', 'descriptor_name': 'Neoplasm Invasiveness', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014407', 'descriptor_name': 'Tumor Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1349-7006.1996.tb03123.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1349-7006.1996.tb03123.x', 'source': {'id': 'https://openalex.org/S4210193983', 'display_name': 'Japanese Journal of Cancer Research', 'issn_l': '0910-5050', 'issn': ['0910-5050', '1344-6428', '1876-4673'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5921007', 'pdf_url': 'https://europepmc.org/articles/pmc5921007?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921007', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9045942', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1349-7006.1996.tb03123.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1349-7006.1996.tb03123.x', 'source': {'id': 'https://openalex.org/S4210193983', 'display_name': 'Japanese Journal of Cancer Research', 'issn_l': '0910-5050', 'issn': ['0910-5050', '1344-6428', '1876-4673'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.48, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 37, 'referenced_works': ['https://openalex.org/W1255813291', 'https://openalex.org/W1277127312', 'https://openalex.org/W1490888974', 'https://openalex.org/W1534652806', 'https://openalex.org/W1536690700', 'https://openalex.org/W1570803984', 'https://openalex.org/W1577897965', 'https://openalex.org/W1635038849', 'https://openalex.org/W1933888786', 'https://openalex.org/W1953290841', 'https://openalex.org/W1981752846', 'https://openalex.org/W1984294894', 'https://openalex.org/W2001189283', 'https://openalex.org/W2002695314', 'https://openalex.org/W2003924835', 'https://openalex.org/W2005367151', 'https://openalex.org/W2005782838', 'https://openalex.org/W2009991832', 'https://openalex.org/W2030482951', 'https://openalex.org/W2031893097', 'https://openalex.org/W2048367533', 'https://openalex.org/W2050825441', 'https://openalex.org/W2054042846', 'https://openalex.org/W2060937867', 'https://openalex.org/W2070715920', 'https://openalex.org/W2070852249', 'https://openalex.org/W2072635469', 'https://openalex.org/W2092151880', 'https://openalex.org/W2113142255', 'https://openalex.org/W2117051009', 'https://openalex.org/W2119738345', 'https://openalex.org/W2140911983', 'https://openalex.org/W2143937597', 'https://openalex.org/W2155493449', 'https://openalex.org/W2157746701', 'https://openalex.org/W2399301246', 'https://openalex.org/W90465349'], 'related_works': ['https://openalex.org/W4361883612', 'https://openalex.org/W3171106033', 'https://openalex.org/W2372073679', 'https://openalex.org/W2338212926', 'https://openalex.org/W2330396769', 'https://openalex.org/W2114732323', 'https://openalex.org/W2103094929', 'https://openalex.org/W2071184351', 'https://openalex.org/W2041862716', 'https://openalex.org/W1511529197'], 'abstract_inverted_index': {'Fibroblasts': [0, 113], 'have': [1], 'been': [2], 'considered': [3], 'to': [4, 14, 20, 128, 190], 'play': [5], 'an': [6, 24, 169], 'important': [7, 170], 'role': [8], 'in': [9, 87, 154, 159], 'tumor': [10, 21, 126, 175, 192], 'progression.': [11], 'In': [12], 'order': [13], 'evaluate': [15], 'the': [16, 55, 64, 83, 98, 111, 160, 179], 'contribution': [17], 'of': [18, 45, 71, 85, 91, 102, 122, 143, 181], 'fibroblasts': [19, 36, 106, 144, 185], 'invasion,': [22, 99, 177], 'TE2‐NS,': [23, 72], 'esophageal': [25, 40, 47], 'cancer': [26, 48, 135], 'cell': [27, 176], 'line,': [28], 'was': [29, 80, 148], 'cultured': [30], 'on': [31], 'collagen': [32], 'gel': [33, 57, 65], 'containing': [34, 58, 67], 'primary': [35], 'derived': [37], 'from': [38, 114, 134, 145], 'normal': [39], 'submucosa': [41], 'or': [42], 'cancerous': [43], 'tissues': [44], 'seven': [46], 'patients.': [49, 195], 'TE2‐NS': [50, 153], 'showed': [51], 'diverse': [52], 'invasiveness': [53, 70], 'into': [54, 110], 'underlying': [56], 'fibroblasts,': [59], 'but': [60, 100, 157], 'did': [61], 'not': [62, 66, 158], 'invade': [63], 'fibroblasts.': [68], 'The': [69], 'which': [73, 173], 'expressed': [74], 'hepatocyte': [75], 'growth': [76], 'factor': [77, 172], '(HGF)': [78], 'receptor,': [79], 'well‐correlated': [81], 'with': [82, 137, 152], 'concentration': [84], 'HGF': [86, 95, 104, 123, 141, 167, 182], 'conditioned': [88], 'medium.': [89], 'Administration': [90], 'neutralizing': [92], 'antibody': [93], 'against': [94], 'effectively': [96], 'suppressed': [97], 'application': [101], 'recombinant': [103], 'without': [105], 'induced': [107, 125], 'little': [108], 'invasion': [109, 127, 193], 'gel.': [112], 'non‐cancerous': [115, 146], 'tissue': [116, 147], 'generally': [117], 'secreted': [118], 'a': [119, 129], 'larger': [120], 'amount': [121], 'and': [124, 178], 'greater': [130], 'extent': [131], 'than': [132], 'those': [133], 'tissue,': [136], 'large': [138], 'diversity.': [139], 'Interestingly,': [140], 'secretion': [142], 'stimulated': [149], 'by': [150, 184], 'co‐culture': [151], 'two': [155], 'lines,': [156], 'other': [161], 'four.': [162], 'These': [163], 'results': [164], 'indicate': [165], 'that': [166], 'is': [168], 'paracrine': [171], 'induces': [174], 'diversity': [180], 'production': [183], 'might': [186], 'suggest': [187], 'different': [188], 'potentiality': [189], 'induce': [191], 'among': [194]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2041862716', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-08-15T06:39:41.016439', 'created_date': '2016-06-24'}