Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2041605613', 'doi': 'https://doi.org/10.1016/j.annemergmed.2013.05.026', 'title': 'Rapid Reversal of Warfarin-Associated Hemorrhage in the Emergency Department by Prothrombin Complex Concentrates', 'display_name': 'Rapid Reversal of Warfarin-Associated Hemorrhage in the Emergency Department by Prothrombin Complex Concentrates', 'publication_year': 2013, 'publication_date': '2013-12-01', 'ids': {'openalex': 'https://openalex.org/W2041605613', 'doi': 'https://doi.org/10.1016/j.annemergmed.2013.05.026', 'mag': '2041605613', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23829955'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.annemergmed.2013.05.026', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S116012647', 'display_name': 'Annals of Emergency Medicine', 'issn_l': '0196-0644', 'issn': ['0196-0644', '1085-8717', '1097-6760'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5010693129', 'display_name': 'Kenneth Frumkin', 'orcid': 'https://orcid.org/0000-0001-6400-9088'}, 'institutions': [{'id': 'https://openalex.org/I1303481939', 'display_name': 'Naval Medical Center Portsmouth', 'ror': 'https://ror.org/04vxq1969', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1303481939', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Kenneth Frumkin', 'raw_affiliation_strings': ['Emergency Medicine Department, Naval Medical Center Portsmouth, VA'], 'affiliations': [{'raw_affiliation_string': 'Emergency Medicine Department, Naval Medical Center Portsmouth, VA', 'institution_ids': ['https://openalex.org/I1303481939']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5010693129'], 'corresponding_institution_ids': ['https://openalex.org/I1303481939'], 'apc_list': {'value': 3850, 'currency': 'USD', 'value_usd': 3850, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.387, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 19, 'citation_normalized_percentile': {'value': 0.723214, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '62', 'issue': '6', 'first_page': '616', 'last_page': '626.e8'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11116', 'display_name': 'Fluid Resuscitation in Trauma and Critical Care', 'score': 0.9959, 'subfield': {'id': 'https://openalex.org/subfields/2706', 'display_name': 'Critical Care and Intensive Care Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11116', 'display_name': 'Fluid Resuscitation in Trauma and Critical Care', 'score': 0.9959, 'subfield': {'id': 'https://openalex.org/subfields/2706', 'display_name': 'Critical Care and Intensive Care Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10065', 'display_name': 'Atrial Fibrillation', 'score': 0.9954, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11763', 'display_name': 'Management and Pathophysiology of Intracerebral Hemorrhage', 'score': 0.9893, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/prothrombin-complex-concentrate', 'display_name': 'Prothrombin complex concentrate', 'score': 0.964231}, {'id': 'https://openalex.org/keywords/fresh-frozen-plasma', 'display_name': 'Fresh frozen plasma', 'score': 0.9597032}, {'id': 'https://openalex.org/keywords/prothrombin-complex', 'display_name': 'PROTHROMBIN COMPLEX', 'score': 0.7757822}, {'id': 'https://openalex.org/keywords/recombinant-factor-viia', 'display_name': 'Recombinant Factor VIIa', 'score': 0.509046}, {'id': 'https://openalex.org/keywords/vitamin-k-antagonist', 'display_name': 'Vitamin K antagonist', 'score': 0.45804068}], 'concepts': [{'id': 'https://openalex.org/C2777091921', 'wikidata': 'https://www.wikidata.org/wiki/Q2044524', 'display_name': 'Prothrombin complex concentrate', 'level': 4, 'score': 0.964231}, {'id': 'https://openalex.org/C66112548', 'wikidata': 'https://www.wikidata.org/wiki/Q1225698', 'display_name': 'Fresh frozen plasma', 'level': 3, 'score': 0.9597032}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9359353}, {'id': 'https://openalex.org/C2776301958', 'wikidata': 'https://www.wikidata.org/wiki/Q407431', 'display_name': 'Warfarin', 'level': 3, 'score': 0.9306278}, {'id': 'https://openalex.org/C2909974469', 'wikidata': 'https://www.wikidata.org/wiki/Q2044524', 'display_name': 'PROTHROMBIN COMPLEX', 'level': 3, 'score': 0.7757822}, {'id': 'https://openalex.org/C2778961111', 'wikidata': 'https://www.wikidata.org/wiki/Q5940878', 'display_name': 'Recombinant factor VIIa', 'level': 2, 'score': 0.66356164}, {'id': 'https://openalex.org/C2780724011', 'wikidata': 'https://www.wikidata.org/wiki/Q1295316', 'display_name': 'Emergency department', 'level': 2, 'score': 0.6012376}, {'id': 'https://openalex.org/C2993590494', 'wikidata': 'https://www.wikidata.org/wiki/Q182338', 'display_name': 'Vitamin k', 'level': 2, 'score': 0.49150667}, {'id': 'https://openalex.org/C2776704044', 'wikidata': 'https://www.wikidata.org/wiki/Q2852541', 'display_name': 'Vitamin K antagonist', 'level': 4, 'score': 0.45804068}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.35435194}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.34884375}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.33890462}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.23426428}, {'id': 'https://openalex.org/C2778382381', 'wikidata': 'https://www.wikidata.org/wiki/Q179217', 'display_name': 'Coagulation', 'level': 2, 'score': 0.18526077}, {'id': 'https://openalex.org/C2779161974', 'wikidata': 'https://www.wikidata.org/wiki/Q815819', 'display_name': 'Atrial fibrillation', 'level': 2, 'score': 0.0781185}, {'id': 'https://openalex.org/C89560881', 'wikidata': 'https://www.wikidata.org/wiki/Q101026', 'display_name': 'Platelet', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000925', 'descriptor_name': 'Anticoagulants', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D001779', 'descriptor_name': 'Blood Coagulation Factors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D004636', 'descriptor_name': 'Emergency Service, Hospital', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006470', 'descriptor_name': 'Hemorrhage', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': True}, {'descriptor_ui': 'D014859', 'descriptor_name': 'Warfarin', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D000925', 'descriptor_name': 'Anticoagulants', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D000925', 'descriptor_name': 'Anticoagulants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001779', 'descriptor_name': 'Blood Coagulation Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002985', 'descriptor_name': 'Clinical Protocols', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015942', 'descriptor_name': 'Factor VIIa', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D015942', 'descriptor_name': 'Factor VIIa', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006470', 'descriptor_name': 'Hemorrhage', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D006470', 'descriptor_name': 'Hemorrhage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010949', 'descriptor_name': 'Plasma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014859', 'descriptor_name': 'Warfarin', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D014859', 'descriptor_name': 'Warfarin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.annemergmed.2013.05.026', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S116012647', 'display_name': 'Annals of Emergency Medicine', 'issn_l': '0196-0644', 'issn': ['0196-0644', '1085-8717', '1097-6760'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23829955', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.79, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 179, 'referenced_works': ['https://openalex.org/W104784625', 'https://openalex.org/W119219662', 'https://openalex.org/W1496176026', 'https://openalex.org/W1496495751', 'https://openalex.org/W1511722589', 'https://openalex.org/W1518149871', 'https://openalex.org/W1555146896', 'https://openalex.org/W1563967546', 'https://openalex.org/W1566673589', 'https://openalex.org/W1653318174', 'https://openalex.org/W1716364657', 'https://openalex.org/W1758702260', 'https://openalex.org/W176534838', 'https://openalex.org/W1824315968', 'https://openalex.org/W1916118824', 'https://openalex.org/W1922017495', 'https://openalex.org/W1965695013', 'https://openalex.org/W1966222151', 'https://openalex.org/W1969628768', 'https://openalex.org/W1970408568', 'https://openalex.org/W1972516474', 'https://openalex.org/W1973511791', 'https://openalex.org/W1976071809', 'https://openalex.org/W1977050755', 'https://openalex.org/W1979888396', 'https://openalex.org/W1980319135', 'https://openalex.org/W1980390900', 'https://openalex.org/W1980595649', 'https://openalex.org/W1981166715', 'https://openalex.org/W1982083319', 'https://openalex.org/W1982487316', 'https://openalex.org/W1982664841', 'https://openalex.org/W1984564593', 'https://openalex.org/W1984648226', 'https://openalex.org/W1986546417', 'https://openalex.org/W1991755700', 'https://openalex.org/W1996528806', 'https://openalex.org/W1998104558', 'https://openalex.org/W1999235052', 'https://openalex.org/W2000180054', 'https://openalex.org/W2001169909', 'https://openalex.org/W2001272791', 'https://openalex.org/W2001643101', 'https://openalex.org/W2001661061', 'https://openalex.org/W2009555992', 'https://openalex.org/W2013864258', 'https://openalex.org/W2014312811', 'https://openalex.org/W2014758509', 'https://openalex.org/W2015117150', 'https://openalex.org/W2015809256', 'https://openalex.org/W2017026770', 'https://openalex.org/W2018237487', 'https://openalex.org/W2018241240', 'https://openalex.org/W2020018325', 'https://openalex.org/W2020068593', 'https://openalex.org/W2020578825', 'https://openalex.org/W2020678913', 'https://openalex.org/W2020689733', 'https://openalex.org/W2021074681', 'https://openalex.org/W2021472508', 'https://openalex.org/W2021556330', 'https://openalex.org/W2022008771', 'https://openalex.org/W2022080618', 'https://openalex.org/W2022348489', 'https://openalex.org/W2023267145', 'https://openalex.org/W2025478649', 'https://openalex.org/W2028568079', 'https://openalex.org/W2031273634', 'https://openalex.org/W2031759462', 'https://openalex.org/W2031990245', 'https://openalex.org/W2033072987', 'https://openalex.org/W2038433315', 'https://openalex.org/W2042603596', 'https://openalex.org/W2042688215', 'https://openalex.org/W2043113187', 'https://openalex.org/W2043747195', 'https://openalex.org/W2044129244', 'https://openalex.org/W2045169807', 'https://openalex.org/W2045644486', 'https://openalex.org/W2047707618', 'https://openalex.org/W2048269822', 'https://openalex.org/W2049901839', 'https://openalex.org/W2051548515', 'https://openalex.org/W2053209897', 'https://openalex.org/W2058128077', 'https://openalex.org/W2058308598', 'https://openalex.org/W2058400674', 'https://openalex.org/W2058821379', 'https://openalex.org/W2059014224', 'https://openalex.org/W2064925106', 'https://openalex.org/W2067636854', 'https://openalex.org/W2068294482', 'https://openalex.org/W2069273332', 'https://openalex.org/W2070658389', 'https://openalex.org/W2071399101', 'https://openalex.org/W2071688599', 'https://openalex.org/W2071718709', 'https://openalex.org/W2072471714', 'https://openalex.org/W2072662439', 'https://openalex.org/W2072829757', 'https://openalex.org/W2072836104', 'https://openalex.org/W2075238363', 'https://openalex.org/W2076438380', 'https://openalex.org/W2076954584', 'https://openalex.org/W2077833540', 'https://openalex.org/W2079197199', 'https://openalex.org/W2079259978', 'https://openalex.org/W2081293034', 'https://openalex.org/W2081794820', 'https://openalex.org/W2081889559', 'https://openalex.org/W2082814100', 'https://openalex.org/W2086550134', 'https://openalex.org/W2086977057', 'https://openalex.org/W2088604835', 'https://openalex.org/W2088707870', 'https://openalex.org/W2091110852', 'https://openalex.org/W2092060277', 'https://openalex.org/W2092177028', 'https://openalex.org/W2092992754', 'https://openalex.org/W2094585602', 'https://openalex.org/W2095402186', 'https://openalex.org/W2096051551', 'https://openalex.org/W2101438273', 'https://openalex.org/W2101982080', 'https://openalex.org/W2104286300', 'https://openalex.org/W2104835969', 'https://openalex.org/W2106722871', 'https://openalex.org/W2108921931', 'https://openalex.org/W2108988937', 'https://openalex.org/W2115446024', 'https://openalex.org/W2115696894', 'https://openalex.org/W2118340301', 'https://openalex.org/W2118476830', 'https://openalex.org/W2121392791', 'https://openalex.org/W2124142208', 'https://openalex.org/W2126506324', 'https://openalex.org/W2126603651', 'https://openalex.org/W2127079385', 'https://openalex.org/W2127103113', 'https://openalex.org/W2127787916', 'https://openalex.org/W2128485851', 'https://openalex.org/W2130487729', 'https://openalex.org/W2131248096', 'https://openalex.org/W2138238488', 'https://openalex.org/W2143829405', 'https://openalex.org/W2144129764', 'https://openalex.org/W2147549352', 'https://openalex.org/W2149071603', 'https://openalex.org/W2150752234', 'https://openalex.org/W2152758372', 'https://openalex.org/W2153350446', 'https://openalex.org/W2153636570', 'https://openalex.org/W2153971536', 'https://openalex.org/W2154537473', 'https://openalex.org/W2156687558', 'https://openalex.org/W2157750317', 'https://openalex.org/W2157822705', 'https://openalex.org/W2158203908', 'https://openalex.org/W2158889560', 'https://openalex.org/W2159149367', 'https://openalex.org/W2161369674', 'https://openalex.org/W2161734919', 'https://openalex.org/W2163334011', 'https://openalex.org/W2168492365', 'https://openalex.org/W2169670745', 'https://openalex.org/W2172150766', 'https://openalex.org/W2172255405', 'https://openalex.org/W2333136077', 'https://openalex.org/W2410033362', 'https://openalex.org/W2471666488', 'https://openalex.org/W3171831654', 'https://openalex.org/W37849039', 'https://openalex.org/W4231993637', 'https://openalex.org/W4237953286', 'https://openalex.org/W4245917296', 'https://openalex.org/W4249252758', 'https://openalex.org/W4285719527', 'https://openalex.org/W4317929383', 'https://openalex.org/W5756051'], 'related_works': ['https://openalex.org/W2605187573', 'https://openalex.org/W2341828612', 'https://openalex.org/W2304698973', 'https://openalex.org/W2278994024', 'https://openalex.org/W2168492365', 'https://openalex.org/W2151962760', 'https://openalex.org/W2088707870', 'https://openalex.org/W2057606773', 'https://openalex.org/W2041605613', 'https://openalex.org/W104778587'], 'abstract_inverted_index': {'Life-threatening': [0], 'warfarin-associated': [1], 'hemorrhage': [2], 'is': [3], 'common,': [4], 'with': [5, 65], 'a': [6, 80], 'high': [7], 'mortality.': [8], 'In': [9], 'the': [10, 13, 34, 59], 'United': [11, 35], 'States,': [12, 36], 'most': [14], 'commonly': [15], 'used': [16, 42], 'therapies--fresh': [17], 'frozen': [18, 67], 'plasma': [19, 46], 'and': [20, 24, 26, 72, 76], 'vitamin': [21], 'K--are': [22], 'slow': [23], 'unpredictable': [25], 'can': [27], 'result': [28], 'in': [29, 51], 'volume': [30], 'overload.': [31], 'Outside': [32], 'of': [33], 'prothrombin': [37, 69], 'complex': [38, 70], 'concentrates': [39], 'are': [40], 'often': [41], 'instead;': [43], 'these': [44], 'pooled': [45], 'products': [47], 'reverse': [48], 'warfarin': [49, 63], 'anticoagulation': [50], 'minutes': [52], 'rather': [53], 'than': [54], 'hours.': [55], 'This': [56], 'article': [57], 'reviews': [58], 'literature': [60], 'relating': [61], 'to': [62], 'reversal': [64], 'fresh': [66], 'plasma,': [68], 'concentrates,': [71], 'recombinant': [73], 'factor': [74], 'VIIa': [75], 'provides': [77], 'elements': [78], 'for': [79], 'management': [81], 'protocol': [82], 'based': [83], 'on': [84], 'this': [85], 'literature.': [86]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2041605613', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-08-15T06:39:11.905331', 'created_date': '2016-06-24'}