Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2041371211', 'doi': 'https://doi.org/10.1523/jneurosci.3429-05.2005', 'title': 'Wnt Signaling in Neural Circuit Development', 'display_name': 'Wnt Signaling in Neural Circuit Development', 'publication_year': 2005, 'publication_date': '2005-11-09', 'ids': {'openalex': 'https://openalex.org/W2041371211', 'doi': 'https://doi.org/10.1523/jneurosci.3429-05.2005', 'mag': '2041371211', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16280576', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6725830'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1523/jneurosci.3429-05.2005', 'pdf_url': 'https://www.jneurosci.org/content/jneuro/25/45/10376.full.pdf', 'source': {'id': 'https://openalex.org/S5555990', 'display_name': 'Journal of Neuroscience', 'issn_l': '0270-6474', 'issn': ['0270-6474', '1529-2401'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319739', 'host_organization_name': 'Society for Neuroscience', 'host_organization_lineage': ['https://openalex.org/P4310319739'], 'host_organization_lineage_names': ['Society for Neuroscience'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://www.jneurosci.org/content/jneuro/25/45/10376.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5057216891', 'display_name': 'Lee G. Fradkin', 'orcid': 'https://orcid.org/0000-0002-5282-2984'}, 'institutions': [{'id': 'https://openalex.org/I2800006345', 'display_name': 'Leiden University Medical Center', 'ror': 'https://ror.org/05xvt9f17', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800006345']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Lee G. Fradkin', 'raw_affiliation_strings': ['Department of Molecular and Cell Biology, Leiden University Medical Center, 2333 AL, Leiden, The Netherlands.'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Cell Biology, Leiden University Medical Center, 2333 AL, Leiden, The Netherlands.', 'institution_ids': ['https://openalex.org/I2800006345']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011083543', 'display_name': 'Gian Garriga', 'orcid': 'https://orcid.org/0000-0003-3641-9439'}, 'institutions': [{'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gian Garriga', 'raw_affiliation_strings': ['Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720,'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720,', 'institution_ids': ['https://openalex.org/I95457486']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020195440', 'display_name': 'Patricia C. Salinas', 'orcid': 'https://orcid.org/0000-0002-5748-083X'}, 'institutions': [{'id': 'https://openalex.org/I45129253', 'display_name': 'University College London', 'ror': 'https://ror.org/02jx3x895', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I124357947', 'https://openalex.org/I45129253']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Patricia C. Salinas', 'raw_affiliation_strings': ['Department of Anatomy and Developmental Biology, University College London, London WC1E 6BT, United Kingdom,'], 'affiliations': [{'raw_affiliation_string': 'Department of Anatomy and Developmental Biology, University College London, London WC1E 6BT, United Kingdom,', 'institution_ids': ['https://openalex.org/I45129253']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103114998', 'display_name': 'John B. Thomas', 'orcid': 'https://orcid.org/0000-0002-0348-2709'}, 'institutions': [{'id': 'https://openalex.org/I1307098950', 'display_name': 'Salk Institute for Biological Studies', 'ror': 'https://ror.org/03xez1567', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1307098950']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'John B. Thomas', 'raw_affiliation_strings': ['Salk Institute, San Diego, California 92186,'], 'affiliations': [{'raw_affiliation_string': 'Salk Institute, San Diego, California 92186,', 'institution_ids': ['https://openalex.org/I1307098950']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009703635', 'display_name': 'Xiang Yu', 'orcid': 'https://orcid.org/0000-0003-1225-7666'}, 'institutions': [{'id': 'https://openalex.org/I19820366', 'display_name': 'Chinese Academy of Sciences', 'ror': 'https://ror.org/034t30j35', 'country_code': 'CN', 'type': 'government', 'lineage': ['https://openalex.org/I19820366']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiang Yu', 'raw_affiliation_strings': ['Institute of Neuroscience, Chinese Academy of Sciences, Shanghai 200031, China, and'], 'affiliations': [{'raw_affiliation_string': 'Institute of Neuroscience, Chinese Academy of Sciences, Shanghai 200031, China, and', 'institution_ids': ['https://openalex.org/I19820366']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5074354492', 'display_name': 'Yimin Zou', 'orcid': 'https://orcid.org/0000-0002-1092-5547'}, 'institutions': [{'id': 'https://openalex.org/I40347166', 'display_name': 'University of Chicago', 'ror': 'https://ror.org/024mw5h28', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I40347166']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Yimin Zou', 'raw_affiliation_strings': ['Department of Neurobiology, Pharmacology, and Physiology, The University of Chicago, Chicago, Illinois 60637'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurobiology, Pharmacology, and Physiology, The University of Chicago, Chicago, Illinois 60637', 'institution_ids': ['https://openalex.org/I40347166']}]}], 'countries_distinct_count': 4, 'institutions_distinct_count': 6, 'corresponding_author_ids': ['https://openalex.org/A5074354492'], 'corresponding_institution_ids': ['https://openalex.org/I40347166'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.488, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 32, 'citation_normalized_percentile': {'value': 0.43355, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '25', 'issue': '45', 'first_page': '10376', 'last_page': '10378'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10929', 'display_name': 'Wnt Signaling in Development and Disease', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10929', 'display_name': 'Wnt Signaling in Development and Disease', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12061', 'display_name': 'Molecular Mechanisms of Axon Guidance', 'score': 0.9952, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10268', 'display_name': 'Notch Signaling Pathway in Development and Disease', 'score': 0.9951, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/wnt-signaling', 'display_name': 'Wnt Signaling', 'score': 0.690294}, {'id': 'https://openalex.org/keywords/lrp6', 'display_name': 'LRP6', 'score': 0.68418986}, {'id': 'https://openalex.org/keywords/cell-signaling', 'display_name': 'Cell Signaling', 'score': 0.593192}, {'id': 'https://openalex.org/keywords/cell-fate-determination', 'display_name': 'Cell fate determination', 'score': 0.5833832}, {'id': 'https://openalex.org/keywords/neural-development', 'display_name': 'Neural development', 'score': 0.5831088}, {'id': 'https://openalex.org/keywords/vascular-patterning', 'display_name': 'Vascular patterning', 'score': 0.514731}, {'id': 'https://openalex.org/keywords/lrp5', 'display_name': 'LRP5', 'score': 0.49804854}, {'id': 'https://openalex.org/keywords/neural-cell', 'display_name': 'Neural cell', 'score': 0.4220705}], 'concepts': [{'id': 'https://openalex.org/C137620995', 'wikidata': 'https://www.wikidata.org/wiki/Q155769', 'display_name': 'Wnt signaling pathway', 'level': 3, 'score': 0.95686525}, {'id': 'https://openalex.org/C170320316', 'wikidata': 'https://www.wikidata.org/wiki/Q18028667', 'display_name': 'LRP6', 'level': 4, 'score': 0.68418986}, {'id': 'https://openalex.org/C163952510', 'wikidata': 'https://www.wikidata.org/wiki/Q5058196', 'display_name': 'Cell fate determination', 'level': 4, 'score': 0.5833832}, {'id': 'https://openalex.org/C461258', 'wikidata': 'https://www.wikidata.org/wiki/Q1345738', 'display_name': 'Neural development', 'level': 3, 'score': 0.5831088}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5731041}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.56016076}, {'id': 'https://openalex.org/C182819311', 'wikidata': 'https://www.wikidata.org/wiki/Q18028670', 'display_name': 'LRP5', 'level': 4, 'score': 0.49804854}, {'id': 'https://openalex.org/C145103041', 'wikidata': 'https://www.wikidata.org/wiki/Q1151519', 'display_name': 'Embryonic stem cell', 'level': 3, 'score': 0.48961288}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.48788762}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.44948986}, {'id': 'https://openalex.org/C2992459734', 'wikidata': 'https://www.wikidata.org/wiki/Q43054', 'display_name': 'Neural cell', 'level': 3, 'score': 0.4220705}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.40312117}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.20230544}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0793879}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.06284323}], 'mesh': [{'descriptor_ui': 'D009415', 'descriptor_name': 'Nerve Net', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D051153', 'descriptor_name': 'Wnt Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009415', 'descriptor_name': 'Nerve Net', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D009415', 'descriptor_name': 'Nerve Net', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051153', 'descriptor_name': 'Wnt Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1523/jneurosci.3429-05.2005', 'pdf_url': 'https://www.jneurosci.org/content/jneuro/25/45/10376.full.pdf', 'source': {'id': 'https://openalex.org/S5555990', 'display_name': 'Journal of Neuroscience', 'issn_l': '0270-6474', 'issn': ['0270-6474', '1529-2401'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319739', 'host_organization_name': 'Society for Neuroscience', 'host_organization_lineage': ['https://openalex.org/P4310319739'], 'host_organization_lineage_names': ['Society for Neuroscience'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6725830', 'pdf_url': 'https://europepmc.org/articles/pmc6725830?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6725830', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16280576', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1523/jneurosci.3429-05.2005', 'pdf_url': 'https://www.jneurosci.org/content/jneuro/25/45/10376.full.pdf', 'source': {'id': 'https://openalex.org/S5555990', 'display_name': 'Journal of Neuroscience', 'issn_l': '0270-6474', 'issn': ['0270-6474', '1529-2401'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319739', 'host_organization_name': 'Society for Neuroscience', 'host_organization_lineage': ['https://openalex.org/P4310319739'], 'host_organization_lineage_names': ['Society for Neuroscience'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.54, 'id': 'https://metadata.un.org/sdg/14', 'display_name': 'Life below water'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 23, 'referenced_works': ['https://openalex.org/W1549831272', 'https://openalex.org/W1603850560', 'https://openalex.org/W1642049387', 'https://openalex.org/W1983145618', 'https://openalex.org/W1989184804', 'https://openalex.org/W1993513195', 'https://openalex.org/W2004172485', 'https://openalex.org/W2004191360', 'https://openalex.org/W2014574033', 'https://openalex.org/W2015222495', 'https://openalex.org/W2033358116', 'https://openalex.org/W2047293798', 'https://openalex.org/W2054207274', 'https://openalex.org/W2074225039', 'https://openalex.org/W2076817049', 'https://openalex.org/W2080698552', 'https://openalex.org/W2083393999', 'https://openalex.org/W2086611394', 'https://openalex.org/W2087203385', 'https://openalex.org/W2091138883', 'https://openalex.org/W2098924417', 'https://openalex.org/W2142480219', 'https://openalex.org/W2165061154'], 'related_works': ['https://openalex.org/W4360873894', 'https://openalex.org/W4307544679', 'https://openalex.org/W4250009627', 'https://openalex.org/W4239267783', 'https://openalex.org/W2399252004', 'https://openalex.org/W2071497196', 'https://openalex.org/W2060954315', 'https://openalex.org/W2041371211', 'https://openalex.org/W1573333099', 'https://openalex.org/W1527340722'], 'abstract_inverted_index': {'The': [0], 'Wingless-type': [1], '(Wnt)': [2], 'family': [3], 'proteins': [4], 'are': [5], 'well': [6], 'known': [7], 'for': [8], 'their': [9], 'functions': [10], 'in': [11, 38], 'embryonic': [12], 'patterning,': [13], 'cell': [14, 18], 'fate': [15], 'determination,': [16], 'and': [17, 21, 29], 'proliferation': [19], '([Wodarz': [20], 'Nusse,': [22], '1998][1]).': [23], 'Wnts': [24], 'act': [25], 'through': [26], 'both': [27], 'canonical': [28], 'noncanonical': [30], 'signal': [31], 'transduction': [32], 'pathways.': [33], 'Canonical': [34], 'Wnt': [35], 'signaling': [36], 'results': [37], 'the': [39]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2041371211', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-08-15T06:38:43.217476', 'created_date': '2016-06-24'}