Title: Proton magnetic resonance spectroscopy of brain metabolites in galactosemia
Abstract:Abstract Brain edema may occur in infants with galactosemia and has been associated with accumulation of galactitol. Proton magnetic resonance spectra were obtained from 12 patients (four newly diagno...Abstract Brain edema may occur in infants with galactosemia and has been associated with accumulation of galactitol. Proton magnetic resonance spectra were obtained from 12 patients (four newly diagnosed neonates and eight patients on galactose‐restricted diets, age range 1.7–47 years) and control subjects to measure brain galactitol levels in vivo and correlate them with urinary galactitol excretion. The results demonstrate that a markedly elevated brain galactitol level may be present only in newborn infants with galactosemia who exhibit massive urinary galactitol excretion.Read More
Publication Year: 2001
Publication Date: 2001-07-30
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 42
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