Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2039539566', 'doi': 'https://doi.org/10.1177/0961203312441046', 'title': 'Successful tocilizumab and tacrolimus treatment in a patient with rheumatoid arthritis complicated by systemic lupus erythematosus', 'display_name': 'Successful tocilizumab and tacrolimus treatment in a patient with rheumatoid arthritis complicated by systemic lupus erythematosus', 'publication_year': 2012, 'publication_date': '2012-03-20', 'ids': {'openalex': 'https://openalex.org/W2039539566', 'doi': 'https://doi.org/10.1177/0961203312441046', 'mag': '2039539566', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22433919'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1177/0961203312441046', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S115920904', 'display_name': 'Lupus', 'issn_l': '0961-2033', 'issn': ['0961-2033', '1477-0962'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320017', 'host_organization_name': 'SAGE Publishing', 'host_organization_lineage': ['https://openalex.org/P4310320017'], 'host_organization_lineage_names': ['SAGE Publishing'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5011313885', 'display_name': 'Keisuke Maeshima', 'orcid': 'https://orcid.org/0000-0002-9251-5997'}, 'institutions': [{'id': 'https://openalex.org/I188815454', 'display_name': 'Oita University', 'ror': 'https://ror.org/01nyv7k26', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I188815454']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'K Maeshima', 'raw_affiliation_strings': ['Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan', 'institution_ids': ['https://openalex.org/I188815454']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069661274', 'display_name': 'Koji Ishii', 'orcid': 'https://orcid.org/0000-0002-8502-4532'}, 'institutions': [{'id': 'https://openalex.org/I188815454', 'display_name': 'Oita University', 'ror': 'https://ror.org/01nyv7k26', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I188815454']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'K Ishii', 'raw_affiliation_strings': ['Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan', 'institution_ids': ['https://openalex.org/I188815454']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035619205', 'display_name': 'Masataka Torigoe', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I188815454', 'display_name': 'Oita University', 'ror': 'https://ror.org/01nyv7k26', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I188815454']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'M Torigoe', 'raw_affiliation_strings': ['Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan', 'institution_ids': ['https://openalex.org/I188815454']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068969190', 'display_name': 'Chiharu Imada', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I188815454', 'display_name': 'Oita University', 'ror': 'https://ror.org/01nyv7k26', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I188815454']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'C Imada', 'raw_affiliation_strings': ['Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan', 'institution_ids': ['https://openalex.org/I188815454']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054300116', 'display_name': 'Mikako Iwakura', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I188815454', 'display_name': 'Oita University', 'ror': 'https://ror.org/01nyv7k26', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I188815454']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'M Iwakura', 'raw_affiliation_strings': ['Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan', 'institution_ids': ['https://openalex.org/I188815454']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079425654', 'display_name': 'Hajime Hamasaki', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I188815454', 'display_name': 'Oita University', 'ror': 'https://ror.org/01nyv7k26', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I188815454']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'H Hamasaki', 'raw_affiliation_strings': ['Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan', 'institution_ids': ['https://openalex.org/I188815454']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080821368', 'display_name': 'Misuzu Akamine', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I188815454', 'display_name': 'Oita University', 'ror': 'https://ror.org/01nyv7k26', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I188815454']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'M Akamine', 'raw_affiliation_strings': ['Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan', 'institution_ids': ['https://openalex.org/I188815454']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006413362', 'display_name': 'Miwa Haranaka', 'orcid': 'https://orcid.org/0000-0001-6813-3131'}, 'institutions': [{'id': 'https://openalex.org/I188815454', 'display_name': 'Oita University', 'ror': 'https://ror.org/01nyv7k26', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I188815454']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'M Haranaka', 'raw_affiliation_strings': ['Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan', 'institution_ids': ['https://openalex.org/I188815454']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5070474200', 'display_name': 'Hironobu Yoshimatsu', 'orcid': 'https://orcid.org/0000-0001-5427-817X'}, 'institutions': [{'id': 'https://openalex.org/I188815454', 'display_name': 'Oita University', 'ror': 'https://ror.org/01nyv7k26', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I188815454']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'H Yoshimatsu', 'raw_affiliation_strings': ['Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine I, Faculty of Medicine, Oita University, Oita, Japan', 'institution_ids': ['https://openalex.org/I188815454']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.851, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 16, 'citation_normalized_percentile': {'value': 0.901421, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '21', 'issue': '9', 'first_page': '1003', 'last_page': '1006'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10308', 'display_name': 'Systemic Lupus Erythematosus and Antiphospholipid Syndrome', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10308', 'display_name': 'Systemic Lupus Erythematosus and Antiphospholipid Syndrome', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10200', 'display_name': 'Rheumatoid Arthritis', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11735', 'display_name': 'Guillain-Barré Syndrome and Related Neuropathies', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/prednisolone', 'display_name': 'Prednisolone', 'score': 0.64384794}, {'id': 'https://openalex.org/keywords/tocilizumab', 'display_name': 'Tocilizumab', 'score': 0.63101447}, {'id': 'https://openalex.org/keywords/hydroxychloroquine', 'display_name': 'Hydroxychloroquine', 'score': 0.6236039}, {'id': 'https://openalex.org/keywords/treatment', 'display_name': 'Treatment', 'score': 0.513714}, {'id': 'https://openalex.org/keywords/combination-therapy', 'display_name': 'Combination therapy', 'score': 0.43736464}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9732317}, {'id': 'https://openalex.org/C2909675724', 'wikidata': 'https://www.wikidata.org/wiki/Q411648', 'display_name': 'Tacrolimus', 'level': 3, 'score': 0.7173457}, {'id': 'https://openalex.org/C2777575956', 'wikidata': 'https://www.wikidata.org/wiki/Q187255', 'display_name': 'Rheumatoid arthritis', 'level': 2, 'score': 0.7012268}, {'id': 'https://openalex.org/C2776715498', 'wikidata': 'https://www.wikidata.org/wiki/Q11426176', 'display_name': 'Prednisolone', 'level': 2, 'score': 0.64384794}, {'id': 'https://openalex.org/C2777178219', 'wikidata': 'https://www.wikidata.org/wiki/Q425154', 'display_name': 'Tocilizumab', 'level': 3, 'score': 0.63101447}, {'id': 'https://openalex.org/C2779123688', 'wikidata': 'https://www.wikidata.org/wiki/Q421094', 'display_name': 'Hydroxychloroquine', 'level': 5, 'score': 0.6236039}, {'id': 'https://openalex.org/C2776760755', 'wikidata': 'https://www.wikidata.org/wiki/Q18939', 'display_name': 'Azathioprine', 'level': 3, 'score': 0.60355765}, {'id': 'https://openalex.org/C149443304', 'wikidata': 'https://www.wikidata.org/wiki/Q185390', 'display_name': 'Anti-nuclear antibody', 'level': 4, 'score': 0.59186536}, {'id': 'https://openalex.org/C2778917330', 'wikidata': 'https://www.wikidata.org/wiki/Q1274464', 'display_name': 'Polyarthritis', 'level': 3, 'score': 0.5850403}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.5205308}, {'id': 'https://openalex.org/C2776755627', 'wikidata': 'https://www.wikidata.org/wiki/Q408524', 'display_name': 'Cyclophosphamide', 'level': 3, 'score': 0.4958094}, {'id': 'https://openalex.org/C2776999253', 'wikidata': 'https://www.wikidata.org/wiki/Q1304270', 'display_name': 'Combination therapy', 'level': 2, 'score': 0.43736464}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.43277776}, {'id': 'https://openalex.org/C2777077863', 'wikidata': 'https://www.wikidata.org/wiki/Q170990', 'display_name': 'Arthritis', 'level': 2, 'score': 0.42552203}, {'id': 'https://openalex.org/C2775915377', 'wikidata': 'https://www.wikidata.org/wiki/Q188297', 'display_name': 'Lupus erythematosus', 'level': 3, 'score': 0.42350322}, {'id': 'https://openalex.org/C2776912625', 'wikidata': 'https://www.wikidata.org/wiki/Q1485', 'display_name': 'Systemic lupus erythematosus', 'level': 3, 'score': 0.42114538}, {'id': 'https://openalex.org/C2779912601', 'wikidata': 'https://www.wikidata.org/wiki/Q1621830', 'display_name': 'Lupus nephritis', 'level': 3, 'score': 0.4194162}, {'id': 'https://openalex.org/C16005928', 'wikidata': 'https://www.wikidata.org/wiki/Q171171', 'display_name': 'Dermatology', 'level': 1, 'score': 0.41153324}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.38216284}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.30120668}, {'id': 'https://openalex.org/C163764329', 'wikidata': 'https://www.wikidata.org/wiki/Q785022', 'display_name': 'Autoantibody', 'level': 3, 'score': 0.20300412}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.19230431}, {'id': 'https://openalex.org/C2911091166', 'wikidata': 'https://www.wikidata.org/wiki/Q106419912', 'display_name': 'Transplantation', 'level': 2, 'score': 0.1501764}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.08617911}, {'id': 'https://openalex.org/C3008058167', 'wikidata': 'https://www.wikidata.org/wiki/Q84263196', 'display_name': 'Coronavirus disease 2019 (COVID-19)', 'level': 4, 'score': 0.0}, {'id': 'https://openalex.org/C524204448', 'wikidata': 'https://www.wikidata.org/wiki/Q788926', 'display_name': 'Infectious disease (medical specialty)', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D061067', 'descriptor_name': 'Antibodies, Monoclonal, Humanized', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D007166', 'descriptor_name': 'Immunosuppressive Agents', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D008180', 'descriptor_name': 'Lupus Erythematosus, Systemic', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D016559', 'descriptor_name': 'Tacrolimus', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D061067', 'descriptor_name': 'Antibodies, Monoclonal, Humanized', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001172', 'descriptor_name': 'Arthritis, Rheumatoid', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D004359', 'descriptor_name': 'Drug Therapy, Combination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007166', 'descriptor_name': 'Immunosuppressive Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008180', 'descriptor_name': 'Lupus Erythematosus, Systemic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008180', 'descriptor_name': 'Lupus Erythematosus, Systemic', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D016559', 'descriptor_name': 'Tacrolimus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1177/0961203312441046', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S115920904', 'display_name': 'Lupus', 'issn_l': '0961-2033', 'issn': ['0961-2033', '1477-0962'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320017', 'host_organization_name': 'SAGE Publishing', 'host_organization_lineage': ['https://openalex.org/P4310320017'], 'host_organization_lineage_names': ['SAGE Publishing'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22433919', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.73, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 11, 'referenced_works': ['https://openalex.org/W1984734865', 'https://openalex.org/W2023862046', 'https://openalex.org/W2043298079', 'https://openalex.org/W2049628940', 'https://openalex.org/W2061182345', 'https://openalex.org/W2095151808', 'https://openalex.org/W2104423175', 'https://openalex.org/W2127354755', 'https://openalex.org/W2141738951', 'https://openalex.org/W2515960618', 'https://openalex.org/W4254273933'], 'related_works': ['https://openalex.org/W3153679424', 'https://openalex.org/W3149354770', 'https://openalex.org/W3110506613', 'https://openalex.org/W3096335653', 'https://openalex.org/W3036925868', 'https://openalex.org/W3027791452', 'https://openalex.org/W2520571625', 'https://openalex.org/W2277727625', 'https://openalex.org/W2275736852', 'https://openalex.org/W2093526042'], 'abstract_inverted_index': {'We': [0], 'report': [1, 143], 'a': [2, 21, 126], '37-year-old': [3], 'female': [4], 'of': [5, 23, 50, 76, 112, 118, 129, 137], 'intractable': [6], 'rheumatoid': [7], 'arthritis': [8], '(RA)': [9], 'complicated': [10], 'by': [11], 'systemic': [12], 'lupus': [13], 'erythematosus': [14], '(SLE),': [15], 'who': [16], 'was': [17, 29, 35, 40, 63, 85, 125], 'successfully': [18], 'treated': [19], 'with': [20, 31, 87, 121], 'combination': [22, 119, 149], 'tocilizumab': [24], '(TCZ)': [25], 'and': [26, 39, 46, 59, 73, 82, 90, 101], 'tacrolimus.': [27], 'She': [28, 55], 'diagnosed': [30, 86], 'RA': [32, 130], 'when': [33, 61], 'she': [34, 62], '21': [36], 'years': [37, 65], 'old,': [38], 'administered': [41, 103], 'oral': [42], 'prednisolone,': [43], 'injectable': [44], 'gold': [45], 'salazosulfapyridine,': [47], 'but': [48, 132], 'deformity': [49], 'her': [51], 'hands': [52], 'gradually': [53], 'developed.': [54], 'developed': [56, 93], 'high': [57, 74], 'fever': [58], 'thrombocytopenia': [60], '35': [64], 'old.': [66], 'Renal': [67], 'involvement,': [68], 'pericarditis,': [69], 'positive': [70], 'antinuclear': [71], 'antibody': [72, 79], 'level': [75], 'anti-double-stranded': [77], 'DNA': [78], 'were': [80], 'found': [81], 'the': [83, 116, 134, 145], 'patient': [84], 'SLE.': [88], 'Polyarthritis': [89], 'immunological': [91], 'abnormalities': [92], 'despite': [94], 'aggressive': [95], 'immunosuppressive': [96], 'therapy': [97, 107, 120, 150], 'including': [98], 'high-dose': [99], 'corticosteroids': [100], 'intravenously': [102], 'cyclophosphamide.': [104], 'Tacrolimus': [105], '(TAC)': [106], 'gave': [108], 'only': [109, 124], 'partial': [110], 'improvement': [111], 'joint': [113], 'symptoms.': [114], 'After': [115], 'initiation': [117], 'TCZ,': [122], 'not': [123], 'complete': [127], 'remission': [128], 'obtained,': [131], 'also': [133], 'serum': [135], 'levels': [136], 'SLE': [138, 155], 'markers': [139], 'dramatically': [140], 'decreased.': [141], 'Our': [142], 'suggests': [144], 'possibility': [146], 'that': [147], 'this': [148], 'is': [151], 'effective': [152], 'in': [153], 'treating': [154], 'as': [156, 158], 'well': [157], 'RA.': [159]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2039539566', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-08-13T09:43:39.424071', 'created_date': '2016-06-24'}