Title: Tyrosinase Inhibitory and Anti-Tumor Promoting Activities of Compounds Isolated from Safflower (Carthamus Tinctorius L.) and Cotton (Gossypium Hirsutum L.) Oil Cakes
Abstract:Abstract Tyrosinase inhibitory and anti-tumor promoting activities of 14 compounds isolated from safflower and cotton oil cakes were evaluated together with the two genins of glycosides, trachorogenin...Abstract Tyrosinase inhibitory and anti-tumor promoting activities of 14 compounds isolated from safflower and cotton oil cakes were evaluated together with the two genins of glycosides, trachorogenin (8a) and quercetin (12a). Catechin (11) and quercetin (12a) showed moderate tyrosinase inhibitory activity. N-(p-Coumaroyl)serotonin (1) and its 5-O-glucoside (3) exhibited weak anti-tyrosinase activity, but potent inhibitory activity on melanine production in the assay. Serotonin derivatives (1-4). 2-hydroxyarctiin (8), matairesinol glycoside (9) and sesquiterpene glucosides (13, 14) exhibited potent inhibitory activity on phorbol-12-myristate-13-acetate induced Epstein-Barr virus early antigen activation, which is the short term in vitro assay for anti-tumor-promoting activity.Read More
Publication Year: 2000
Publication Date: 2000-03-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 34
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