Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2038487944', 'doi': 'https://doi.org/10.1002/dvdy.20831', 'title': 'Analysis of origin and growth of the thyroid gland in zebrafish', 'display_name': 'Analysis of origin and growth of the thyroid gland in zebrafish', 'publication_year': 2006, 'publication_date': '2006-05-05', 'ids': {'openalex': 'https://openalex.org/W2038487944', 'doi': 'https://doi.org/10.1002/dvdy.20831', 'mag': '2038487944', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16680726'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/dvdy.20831', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104993753', 'display_name': 'Developmental Dynamics', 'issn_l': '1058-8388', 'issn': ['1058-8388', '1097-0177'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5080772133', 'display_name': 'Burkhard Alt', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I180923762', 'display_name': 'University of Cologne', 'ror': 'https://ror.org/00rcxh774', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I180923762']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Burkhard Alt', 'raw_affiliation_strings': ['Institute for Developmental Biology, University of Cologne, Gyrhofstrasse 17,50923 Köln, Germany.'], 'affiliations': [{'raw_affiliation_string': 'Institute for Developmental Biology, University of Cologne, Gyrhofstrasse 17,50923 Köln, Germany.', 'institution_ids': ['https://openalex.org/I180923762']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034234727', 'display_name': 'Saskia Reibe', 'orcid': 'https://orcid.org/0000-0003-3638-7529'}, 'institutions': [{'id': 'https://openalex.org/I180923762', 'display_name': 'University of Cologne', 'ror': 'https://ror.org/00rcxh774', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I180923762']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Saskia Reibe', 'raw_affiliation_strings': ['Institute for Developmental Biology, University of Cologne, Gyrhofstrasse 17,50923 Köln, Germany.'], 'affiliations': [{'raw_affiliation_string': 'Institute for Developmental Biology, University of Cologne, Gyrhofstrasse 17,50923 Köln, Germany.', 'institution_ids': ['https://openalex.org/I180923762']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050609108', 'display_name': 'Natália Martins Feitosa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I180923762', 'display_name': 'University of Cologne', 'ror': 'https://ror.org/00rcxh774', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I180923762']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Natalia M. Feitosa', 'raw_affiliation_strings': ['Institute for Developmental Biology, University of Cologne, Gyrhofstrasse 17,50923 Köln, Germany.'], 'affiliations': [{'raw_affiliation_string': 'Institute for Developmental Biology, University of Cologne, Gyrhofstrasse 17,50923 Köln, Germany.', 'institution_ids': ['https://openalex.org/I180923762']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011381016', 'display_name': 'Osama A. Elsalini', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I180923762', 'display_name': 'University of Cologne', 'ror': 'https://ror.org/00rcxh774', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I180923762']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Osama A. Elsalini', 'raw_affiliation_strings': ['Institute for Developmental Biology, University of Cologne, Gyrhofstrasse 17,50923 Köln, Germany.'], 'affiliations': [{'raw_affiliation_string': 'Institute for Developmental Biology, University of Cologne, Gyrhofstrasse 17,50923 Köln, Germany.', 'institution_ids': ['https://openalex.org/I180923762']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038664039', 'display_name': 'Thomas Wendl', 'orcid': 'https://orcid.org/0000-0002-1153-7167'}, 'institutions': [{'id': 'https://openalex.org/I180923762', 'display_name': 'University of Cologne', 'ror': 'https://ror.org/00rcxh774', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I180923762']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Thomas Wendl', 'raw_affiliation_strings': ['Institute for Developmental Biology, University of Cologne, Gyrhofstrasse 17,50923 Köln, Germany.'], 'affiliations': [{'raw_affiliation_string': 'Institute for Developmental Biology, University of Cologne, Gyrhofstrasse 17,50923 Köln, Germany.', 'institution_ids': ['https://openalex.org/I180923762']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5059307916', 'display_name': 'Klaus Röhr', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I180923762', 'display_name': 'University of Cologne', 'ror': 'https://ror.org/00rcxh774', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I180923762']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Klaus B. Rohr', 'raw_affiliation_strings': ['Institute for Developmental Biology, University of Cologne, Gyrhofstrasse 17,50923 Köln, Germany.'], 'affiliations': [{'raw_affiliation_string': 'Institute for Developmental Biology, University of Cologne, Gyrhofstrasse 17,50923 Köln, Germany.', 'institution_ids': ['https://openalex.org/I180923762']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4020, 'currency': 'USD', 'value_usd': 4020, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.332, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 162, 'citation_normalized_percentile': {'value': 0.999942, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '235', 'issue': '7', 'first_page': '1872', 'last_page': '1883'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11077', 'display_name': 'Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities', 'score': 0.9957, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11077', 'display_name': 'Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities', 'score': 0.9957, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11677', 'display_name': 'Congenital heart defects research', 'score': 0.9907, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11505', 'display_name': 'Reproductive biology and impacts on aquatic species', 'score': 0.9819, 'subfield': {'id': 'https://openalex.org/subfields/1314', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/endocrine-gland', 'display_name': 'Endocrine gland', 'score': 0.4613455}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.85203373}, {'id': 'https://openalex.org/C526584372', 'wikidata': 'https://www.wikidata.org/wiki/Q16399', 'display_name': 'Thyroid', 'level': 2, 'score': 0.8503763}, {'id': 'https://openalex.org/C2777164004', 'wikidata': 'https://www.wikidata.org/wiki/Q331858', 'display_name': 'Endoderm', 'level': 4, 'score': 0.6183288}, {'id': 'https://openalex.org/C102570824', 'wikidata': 'https://www.wikidata.org/wiki/Q147807', 'display_name': 'Follicle', 'level': 2, 'score': 0.5920354}, {'id': 'https://openalex.org/C2779627488', 'wikidata': 'https://www.wikidata.org/wiki/Q315860', 'display_name': 'Calcitonin', 'level': 2, 'score': 0.5841794}, {'id': 'https://openalex.org/C2776878037', 'wikidata': 'https://www.wikidata.org/wiki/Q169444', 'display_name': 'Zebrafish', 'level': 3, 'score': 0.57555586}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.540714}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.54020053}, {'id': 'https://openalex.org/C187785154', 'wikidata': 'https://www.wikidata.org/wiki/Q5464664', 'display_name': 'Follicular phase', 'level': 2, 'score': 0.47987333}, {'id': 'https://openalex.org/C182203180', 'wikidata': 'https://www.wikidata.org/wiki/Q324663', 'display_name': 'Endocrine gland', 'level': 3, 'score': 0.4613455}, {'id': 'https://openalex.org/C2777216303', 'wikidata': 'https://www.wikidata.org/wiki/Q866324', 'display_name': 'Hair follicle', 'level': 2, 'score': 0.41044334}, {'id': 'https://openalex.org/C145103041', 'wikidata': 'https://www.wikidata.org/wiki/Q1151519', 'display_name': 'Embryonic stem cell', 'level': 3, 'score': 0.3257681}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.17281911}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.071547985}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D013961', 'descriptor_name': 'Thyroid Gland', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': True}, {'descriptor_ui': 'D015027', 'descriptor_name': 'Zebrafish', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': True}, {'descriptor_ui': 'D015027', 'descriptor_name': 'Zebrafish', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002116', 'descriptor_name': 'Calcitonin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002116', 'descriptor_name': 'Calcitonin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019070', 'descriptor_name': 'Cell Lineage', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D019070', 'descriptor_name': 'Cell Lineage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004625', 'descriptor_name': 'Embryo, Nonmammalian', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': False}, {'descriptor_ui': 'D004625', 'descriptor_name': 'Embryo, Nonmammalian', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004707', 'descriptor_name': 'Endoderm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004707', 'descriptor_name': 'Endoderm', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D004707', 'descriptor_name': 'Endoderm', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007814', 'descriptor_name': 'Larva', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D007814', 'descriptor_name': 'Larva', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007814', 'descriptor_name': 'Larva', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009024', 'descriptor_name': 'Morphogenesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013961', 'descriptor_name': 'Thyroid Gland', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013961', 'descriptor_name': 'Thyroid Gland', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': False}, {'descriptor_ui': 'D013961', 'descriptor_name': 'Thyroid Gland', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015027', 'descriptor_name': 'Zebrafish', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D029961', 'descriptor_name': 'Zebrafish Proteins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D029961', 'descriptor_name': 'Zebrafish Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/dvdy.20831', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104993753', 'display_name': 'Developmental Dynamics', 'issn_l': '1058-8388', 'issn': ['1058-8388', '1097-0177'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16680726', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 40, 'referenced_works': ['https://openalex.org/W1489916230', 'https://openalex.org/W1495400959', 'https://openalex.org/W1527223408', 'https://openalex.org/W1767712531', 'https://openalex.org/W1859795936', 'https://openalex.org/W1967419775', 'https://openalex.org/W1977157996', 'https://openalex.org/W1982920741', 'https://openalex.org/W1987338017', 'https://openalex.org/W1996610348', 'https://openalex.org/W1999249427', 'https://openalex.org/W2020128111', 'https://openalex.org/W2032226363', 'https://openalex.org/W2039748624', 'https://openalex.org/W2061956923', 'https://openalex.org/W2062638230', 'https://openalex.org/W2069072867', 'https://openalex.org/W2073447884', 'https://openalex.org/W2076694729', 'https://openalex.org/W2083578935', 'https://openalex.org/W2098597135', 'https://openalex.org/W2109094772', 'https://openalex.org/W2116191709', 'https://openalex.org/W2119287481', 'https://openalex.org/W2119446332', 'https://openalex.org/W2124111326', 'https://openalex.org/W2128722623', 'https://openalex.org/W2139618367', 'https://openalex.org/W2144096654', 'https://openalex.org/W2146410655', 'https://openalex.org/W2149022414', 'https://openalex.org/W2151410031', 'https://openalex.org/W2160922979', 'https://openalex.org/W2166658859', 'https://openalex.org/W2168472739', 'https://openalex.org/W2411519297', 'https://openalex.org/W2415023339', 'https://openalex.org/W35183985', 'https://openalex.org/W4239022737', 'https://openalex.org/W592520988'], 'related_works': ['https://openalex.org/W2555720653', 'https://openalex.org/W2409390576', 'https://openalex.org/W2396320928', 'https://openalex.org/W2393922212', 'https://openalex.org/W2392321483', 'https://openalex.org/W2373241822', 'https://openalex.org/W2368912829', 'https://openalex.org/W2363964233', 'https://openalex.org/W2350964028', 'https://openalex.org/W2350384469'], 'abstract_inverted_index': {'Abstract': [0], 'The': [1, 35, 92], 'zebrafish': [2, 106], 'thyroid': [3, 55, 75, 82, 99, 120], 'gland': [4], 'shows': [5], 'a': [6, 12, 53], 'unique': [7], 'pattern': [8], 'of': [9, 21, 25, 30, 32, 37, 46, 74], 'growth': [10, 31], 'as': [11, 107], 'differentiated': [13], 'endocrine': [14], 'gland.': [15, 34], 'Here,': [16], 'we': [17], 'analyze': [18], 'the': [19, 23, 28, 44, 69, 89, 98, 118, 130], 'onset': [20], 'differentiation,': [22], 'contribution': [24], 'lineages,': [26], 'and': [27, 43, 134], 'mode': [29], 'this': [33], 'expression': [36], 'genes': [38], 'involved': [39], 'in': [40, 100, 105], 'hormone': [41], 'production': [42], 'establishment': [45], 'epithelial': [47], 'polarity': [48], 'show': [49], 'that': [50, 81, 95, 117, 135], 'differentiation': [51], 'into': [52], 'first': [54, 119], 'follicle': [56, 83, 121, 133], 'takes': [57], 'place': [58], 'early': [59], 'during': [60], 'embryonic': [61], 'development.': [62], 'Thyroid': [63], 'follicular': [64], 'tissue': [65], 'then': [66], 'grows': [67], 'along': [68], 'pharyngeal': [70, 90], 'midline,': [71], 'initially': [72], 'independently': [73], 'stimulating': [76], 'hormone.': [77], 'Lineage': [78], 'analysis': [79, 115], 'reveals': [80], 'cells': [84], 'are': [85, 138], 'exclusively': [86], 'recruited': [87], 'from': [88], 'endoderm.': [91], 'ultimobranchial': [93], 'bodies': [94], 'merge': [96], 'with': [97], 'mammals': [101], 'form': [102], 'separate': [103], 'glands': [104], 'visualized': [108], 'by': [109], 'calcitonin': [110], 'precursor': [111], 'gene': [112], 'expression.': [113], 'Mosaic': [114], 'suggests': [116], 'differentiating': [122], 'at': [123], '55': [124], 'hours': [125], 'postfertilization': [126], 'corresponds': [127], 'later': [128], 'to': [129], 'most': [131], 'anterior': [132], 'new': [136], 'follicles': [137], 'added': [139], 'caudally.': [140], 'Developmental': [141], 'Dynamics': [142], '235:1872–1883,': [143], '2006.': [144], '©': [145], '2006': [146], 'Wiley‐Liss,': [147], 'Inc.': [148]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2038487944', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 9}, {'year': 2022, 'cited_by_count': 12}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 11}, {'year': 2019, 'cited_by_count': 10}, {'year': 2018, 'cited_by_count': 13}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 11}, {'year': 2014, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 14}, {'year': 2012, 'cited_by_count': 9}], 'updated_date': '2024-12-30T14:18:40.781671', 'created_date': '2016-06-24'}