Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2037931322', 'doi': 'https://doi.org/10.1161/01.cir.102.20.e167', 'title': 'Plasma Urokinase Antigen and Plasminogen Activator Inhibitor-1 Antigen Levels Predict Angiographic Coronary Restenosis', 'display_name': 'Plasma Urokinase Antigen and Plasminogen Activator Inhibitor-1 Antigen Levels Predict Angiographic Coronary Restenosis', 'publication_year': 2000, 'publication_date': '2000-11-14', 'ids': {'openalex': 'https://openalex.org/W2037931322', 'doi': 'https://doi.org/10.1161/01.cir.102.20.e167', 'mag': '2037931322', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11076837'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1161/01.cir.102.20.e167', 'pdf_url': 'https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.102.20.e167', 'source': {'id': 'https://openalex.org/S116251202', 'display_name': 'Circulation', 'issn_l': '0009-7322', 'issn': ['0009-7322', '1524-4539'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.102.20.e167', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5110045460', 'display_name': 'Uichi Ikeda', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I146500386', 'display_name': 'Jichi Medical University', 'ror': 'https://ror.org/010hz0g26', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I146500386']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Uichi Ikeda', 'raw_affiliation_strings': ['Department of Cardiology, Jichi Medical School, Tochigi 329-0498, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, Jichi Medical School, Tochigi 329-0498, Japan', 'institution_ids': ['https://openalex.org/I146500386']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013731354', 'display_name': 'Yukihiro Hojo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I146500386', 'display_name': 'Jichi Medical University', 'ror': 'https://ror.org/010hz0g26', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I146500386']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yukihiro Hojo', 'raw_affiliation_strings': ['Department of Cardiology, Jichi Medical School, Tochigi 329-0498, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, Jichi Medical School, Tochigi 329-0498, Japan', 'institution_ids': ['https://openalex.org/I146500386']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5068557516', 'display_name': 'Kazuyuki Shimada', 'orcid': 'https://orcid.org/0000-0002-1075-9219'}, 'institutions': [{'id': 'https://openalex.org/I146500386', 'display_name': 'Jichi Medical University', 'ror': 'https://ror.org/010hz0g26', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I146500386']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuyuki Shimada', 'raw_affiliation_strings': ['Department of Cardiology, Jichi Medical School, Tochigi 329-0498, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiology, Jichi Medical School, Tochigi 329-0498, Japan', 'institution_ids': ['https://openalex.org/I146500386']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 2, 'citation_normalized_percentile': {'value': 0.294872, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 65, 'max': 69}, 'biblio': {'volume': '102', 'issue': '20', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10620', 'display_name': 'Protease and Inhibitor Mechanisms', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10620', 'display_name': 'Protease and Inhibitor Mechanisms', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10193', 'display_name': 'Coronary Interventions and Diagnostics', 'score': 0.9936, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10881', 'display_name': 'Blood Coagulation and Thrombosis Mechanisms', 'score': 0.9898, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/plasminogen-activator-inhibitor-1', 'display_name': 'Plasminogen activator inhibitor-1', 'score': 0.4204776}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.87239885}, {'id': 'https://openalex.org/C2778283817', 'wikidata': 'https://www.wikidata.org/wiki/Q6590597', 'display_name': 'Restenosis', 'level': 3, 'score': 0.76243234}, {'id': 'https://openalex.org/C2778259205', 'wikidata': 'https://www.wikidata.org/wiki/Q629460', 'display_name': 'Coronary sinus', 'level': 2, 'score': 0.6705836}, {'id': 'https://openalex.org/C2779679481', 'wikidata': 'https://www.wikidata.org/wiki/Q13581432', 'display_name': 'Plasminogen activator', 'level': 2, 'score': 0.6493921}, {'id': 'https://openalex.org/C164705383', 'wikidata': 'https://www.wikidata.org/wiki/Q10379', 'display_name': 'Cardiology', 'level': 1, 'score': 0.59699863}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.5944064}, {'id': 'https://openalex.org/C2776892390', 'wikidata': 'https://www.wikidata.org/wiki/Q7119591', 'display_name': 'Urokinase', 'level': 2, 'score': 0.52219146}, {'id': 'https://openalex.org/C2780675426', 'wikidata': 'https://www.wikidata.org/wiki/Q410485', 'display_name': 'Plasminogen activator inhibitor-1', 'level': 3, 'score': 0.4204776}, {'id': 'https://openalex.org/C2776572282', 'wikidata': 'https://www.wikidata.org/wiki/Q416351', 'display_name': 'Tissue plasminogen activator', 'level': 2, 'score': 0.41351762}, {'id': 'https://openalex.org/C2778583881', 'wikidata': 'https://www.wikidata.org/wiki/Q1325542', 'display_name': 'Stent', 'level': 2, 'score': 0.20191815}], 'mesh': [{'descriptor_ui': 'D006083', 'descriptor_name': 'Graft Occlusion, Vascular', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': True}, {'descriptor_ui': 'D006083', 'descriptor_name': 'Graft Occlusion, Vascular', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D017395', 'descriptor_name': 'Plasminogen Activator Inhibitor 1', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D014568', 'descriptor_name': 'Urokinase-Type Plasminogen Activator', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D015906', 'descriptor_name': 'Angioplasty, Balloon, Coronary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006083', 'descriptor_name': 'Graft Occlusion, Vascular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006083', 'descriptor_name': 'Graft Occlusion, Vascular', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017395', 'descriptor_name': 'Plasminogen Activator Inhibitor 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011237', 'descriptor_name': 'Predictive Value of Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014568', 'descriptor_name': 'Urokinase-Type Plasminogen Activator', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1161/01.cir.102.20.e167', 'pdf_url': 'https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.102.20.e167', 'source': {'id': 'https://openalex.org/S116251202', 'display_name': 'Circulation', 'issn_l': '0009-7322', 'issn': ['0009-7322', '1524-4539'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11076837', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1161/01.cir.102.20.e167', 'pdf_url': 'https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.102.20.e167', 'source': {'id': 'https://openalex.org/S116251202', 'display_name': 'Circulation', 'issn_l': '0009-7322', 'issn': ['0009-7322', '1524-4539'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/4', 'score': 0.4, 'display_name': 'Quality education'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 1, 'referenced_works': ['https://openalex.org/W1988034880'], 'related_works': ['https://openalex.org/W2466118865', 'https://openalex.org/W2426433410', 'https://openalex.org/W2365163608', 'https://openalex.org/W2114135330', 'https://openalex.org/W2061070006', 'https://openalex.org/W2054958817', 'https://openalex.org/W2038747404', 'https://openalex.org/W2027618512', 'https://openalex.org/W2000605128', 'https://openalex.org/W1995024643'], 'abstract_inverted_index': {'HomeCirculationVol.': [0], '102,': [1, 502], 'No.': [2], '20Plasma': [3], 'Urokinase': [4, 31], 'Antigen': [5, 10, 32, 37], 'and': [6, 33, 47, 75, 110, 140, 144, 184, 190, 209, 214, 217, 262, 284, 324, 327, 346, 370, 419, 426, 436, 463, 482], 'Plasminogen': [7, 34], 'Activator': [8, 35], 'Inhibitor-1': [9, 36], 'Levels': [11, 38], 'Predict': [12, 39], 'Angiographic': [13, 40], 'Coronary': [14, 41], 'Restenosis': [15, 42, 477], 'Free': [16], 'AccessLetterPDF/EPUBAboutView': [17], 'PDFView': [18], 'EPUBSections': [19], 'ToolsAdd': [20], 'to': [21, 398], 'favoritesDownload': [22], 'citationsTrack': [23], 'citationsPermissions': [24], 'ShareShare': [25], 'onFacebookTwitterLinked': [26], 'InMendeleyRedditDiggEmail': [27], 'Jump': [28], 'toFree': [29], 'AccessLetterPDF/EPUBPlasma': [30], 'Uichi': [43, 50], 'Ikeda,': [44], 'Yukihiro': [45, 63], 'Hojo': [46, 65, 361], 'Kazuyuki': [48, 76], 'Shimada': [49, 78], 'IkedaUichi': [51], 'Ikeda': [52, 363], 'Department': [53, 66, 79], 'of': [54, 67, 80, 241, 368, 384, 474], 'Cardiology,': [55, 68, 81], 'Jichi': [56, 69, 82], 'Medical': [57, 70, 83], 'School,': [58, 71, 84], 'Tochigi': [59, 72, 85], '329-0498,': [60, 73, 86], 'Japan': [61, 74, 87], ',': [62], 'HojoYukihiro': [64], 'ShimadaKazuyuki': [77], 'Originally': [88, 513], 'published14': [89], 'Nov': [90], '2000https://doi.org/10.1161/01.CIR.102.20.e167Circulation.': [91], '2000;102:e167To': [92], 'the': [93, 99, 136, 169, 179, 202, 231, 239, 258, 263, 285, 295, 301, 308, 313, 320, 385], 'Editor:We': [94], 'read': [95], 'with': [96, 118, 161, 481], 'great': [97], 'interest': [98], 'article': [100], 'by': [101, 297, 378, 509], 'Strauss': [102, 298, 335], 'et': [103, 299, 341, 365], 'al1': [104], 'on': [105], 'urokinase': [106, 344, 424], 'plasminogen': [107, 111, 219, 281, 347], 'activator': [108, 112, 220, 282, 348], '(uPA)': [109], 'inhibitor-1': [113, 349], '(PAI-1)': [114], 'levels': [115, 148, 155, 200, 221, 240, 256, 283, 326, 351], 'in': [116, 159, 166, 168, 201, 230, 238, 257, 294, 373, 478], 'patients': [117, 160], 'stable': [119], 'angina': [120, 430], 'who': [121], 'underwent': [122], 'percutaneous': [123], 'transluminal': [124], 'coronary': [125, 170, 180, 203, 259, 309, 354, 374, 380, 389, 433], 'angioplasty': [126], '(PTCA).': [127], 'In': [128], 'their': [129], 'study,': [130], 'plasma': [131, 145], 'samples': [132, 175, 303], 'were': [133, 149, 156, 176], 'drawn': [134, 177, 306], 'from': [135, 178, 307], 'antecubital': [137], 'vein': [138], 'before': [139, 183], 'serially': [141], 'after': [142, 172, 193, 212, 227, 269, 432], 'PTCA,': [143, 270, 489], 'uPA': [146, 323], 'antigen': [147, 154, 345, 350, 425], 'significantly': [150, 157, 207, 224], 'higher,': [151], 'whereas': [152, 271], 'PAI-1': [153, 216, 278, 325, 468], 'lower,': [158], 'restenosis.Previously,': [162], 'we': [163, 247, 290], 'investigated': [164], 'changes': [165], 'hemostasis': [167], 'circulation': [171], 'PTCA.': [173, 194, 228], 'Blood': [174], 'sinus': [181, 204, 260, 310, 375], 'immediately': [182], 'after,': [185], 'as': [186, 188], 'well': [187], '4': [189, 208], '24': [191, 210, 225], 'hours': [192, 211, 226], 'We': [195], 'found': [196, 248], 'that': [197, 215, 292], 'tissue': [198, 218, 254, 280], 'factor': [199, 255], 'blood': [205, 261, 302, 376], 'increased': [206, 223], 'PTCA': [213], 'also': [222], 'However,': [229], 'femoral': [232], 'arterial': [233], 'blood,': [234], 'no': [235, 272], 'significant': [236, 250, 273], 'change': [237], 'these': [242], 'markers': [243], 'was': [244, 275], 'observed.2': [245], 'Furthermore,': [246], 'a': [249, 471], 'positive': [251], 'correlation': [252, 274], 'between': [253, 277, 322], 'late': [264, 286], 'loss': [265, 287], 'index': [266], '6': [267], 'months': [268], 'observed': [276], 'or': [279], 'index.': [288], 'Therefore,': [289], 'speculate': [291], 'if,': [293], 'study': [296], 'al,1': [300], 'had': [304], 'been': [305, 331], 'rather': [311], 'than': [312], 'peripheral': [314], 'vein,': [315], 'more': [316], 'definite': [317], 'conclusions': [318], 'regarding': [319], 'relationship': [321], 'restenosis': [328], 'could': [329], 'have': [330], 'obtained.': [332], 'References': [333], '1': [334], 'BH,': [336], 'Lau': [337], 'HK,': [338], 'Bowman': [339], 'KA,': [340], 'al.': [342, 366], 'Plasma': [343, 423], 'predict': [352, 429], 'angiographic': [353], 'restenosis.': [355], 'Circulation.1999;': [356], '100:1616–1622.CrossrefMedlineGoogle': [357], 'Scholar2': [358], 'Mizuno': [359], 'O,': [360, 408], 'Y,': [362, 404], 'U,': [364], 'Assessment': [367], 'coagulation': [369], 'platelet': [371], 'activation': [372], 'induced': [377], 'transcatheter': [379], 'intervention': [381], 'for': [382], 'narrowing': [383], 'left': [386], 'anterior': [387], 'descending': [388], 'artery.': [390], 'Am': [391], 'J': [392], 'Cardiol..2000;': [393], '85:154–160.CrossrefMedlineGoogle': [394], 'Scholar': [395], 'Previous': [396], 'Back': [397], 'top': [399], 'Next': [400], 'FiguresReferencesRelatedDetailsCited': [401], 'By': [402], 'Parfyonova': [403], 'Alekseeva': [405], 'I,': [406], 'Plekhanova': [407], 'Deev': [409], 'A,': [410, 414], 'Titaeva': [411], 'E,': [412, 450], 'Dobrovolsky': [413], 'Gabbasov': [415], 'Z,': [416], 'Lyakishev': [417], 'A': [418], 'Tkachuk': [420], 'V': [421], '(2013)': [422], 'C-reactive': [427], 'protein': [428], 'recurrence': [431], 'angioplasty,': [434], 'Heart': [435, 511], 'Vessels,': [437], '10.1007/s00380-013-0407-1,': [438], '29:5,': [439], '(611-618),': [440], 'Online': [441, 495], 'publication': [442, 496], 'date:': [443, 497], '1-Sep-2014.': [444], 'Prisco': [445], 'D,': [446], 'Fedi': [447], 'S,': [448], 'Antonucci': [449], 'Capanni': [451], 'M,': [452, 456, 458], 'Chiarugi': [453], 'L,': [454], 'Chioccioli': [455], 'Falai': [457], 'Giglioli': [459], 'C,': [460], 'Abbate': [461], 'R': [462], 'Gensini': [464], 'G': [465], '(2001)': [466], 'Postprocedural': [467], 'Activity': [469], 'is': [470], 'Risk': [472], 'Marker': [473], 'Subsequent': [475], 'Clinical': [476], 'Patients': [479], 'Both': [480], 'without': [483], 'Stent': [484], 'Implantation': [485], 'After': [486], 'Elective': [487], 'Balloon': [488], 'Thrombosis': [490], 'Research,': [491], '10.1016/S0049-3848(01)00360-7,': [492], '104:3,': [493], '(181-186),': [494], '1-Nov-2001.': [498], 'November': [499], '14,': [500, 515], '2000Vol': [501], 'Issue': [503], '20Article': [504], 'InformationMetrics': [505], 'Copyright': [506], '©': [507], '2000': [508, 516], 'American': [510], 'Associationhttps://doi.org/10.1161/01.CIR.102.20.e167': [512], 'publishedNovember': [514], 'PDF': [517], 'download': [518], 'Advertisement': [519]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2037931322', 'counts_by_year': [{'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-12-13T05:41:45.623959', 'created_date': '2016-06-24'}