Title: Diuretic activity of <i>Satureja montana</i> subsp. Montana extracts and oil in rats
Abstract: Abstract Three preparations of Satureja montana subsp. montana leaves were tested for diuretic activity in rats: an infusion, a water‐alcohol extract and essential oil. In 1‐day experiments, the cumulative volume of urine was collected during the first 5 h after oral administration of 5 mL/100 g body weight of plant preparation. It was established that all the preparations tested initially caused a decrease in diuresis and subsequently a mild stimulation of diuresis. 0.1% solution of essential oil was considered to be a therapeutic dose, whereas 0.5% and 1% solutions caused toxic symptoms in the animals. A further experiment involving treatment of rats for 3 days with a 10% drug infusion and 0.1% essential oil solution demonstrated the considerable diuretic activity of winter savory.
Publication Year: 1993
Publication Date: 1993-09-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 44
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