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2971, 2987, 2995, 3056, 3080, 3094, 3099, 3125, 3198, 3234, 3239, 3251, 3258, 3282, 3293, 3307, 3312, 3341, 3392, 3411, 3416, 3434, 3485, 3496, 3507, 3518, 3530, 3559, 3562, 3573, 3602, 3647, 3692, 3709, 3737, 3760, 3771, 3823, 3877, 3880, 3899, 3918, 3928, 3965, 3997], 'Clinical': [278, 2323], 'Lipidology,': [279], 'Thrombosis,': [280], 'Prevention': [282], 'Committee': [283], 'Council': [286, 293, 300, 305], 'Nutrition,': [288], 'Physical': [289], 'Activity,': [290], 'Metabolism,': [292], 'Arteriosclerosis,': [295], 'Thrombosis': [296], 'Vascular': [298], 'Biology,': [299], 'Nursing,': [303], 'Kidney': [308], 'in': [309, 388, 437, 448, 493, 624, 650, 659, 666, 700, 712, 754, 772, 805, 817, 879, 935, 985, 996, 1032, 1086, 1095, 1123, 1133, 1174, 1178, 1194, 1199, 1217, 1322, 1344, 1351, 1377, 1382, 1388, 1393, 1397, 1441, 1458, 1538, 1638, 1715, 1741, 1754, 1774, 1804, 1936, 1941, 1955, 1972, 2001, 2080, 2229, 2236, 2268, 2279, 2290, 2318, 2340, 2355, 2408, 2453, 2483, 2548, 2567, 2576, 2806, 2818, 2876, 2933, 2953, 2967, 2983, 3016, 3027, 3035, 3116, 3146, 3221, 3241, 3317, 3338, 3359, 3479, 3488, 3520, 3527, 3547, 3613, 3683, 3686, 3732, 3747, 3800, 3806, 3829, 3836, 3845, 3853, 3863, 3883, 3892, 3910, 3975, 3981], 'Originally': [312], 'published18': [313], 'Apr': [314], '2011https://doi.org/10.1161/CIR.0b013e3182160726Circulation.': [315], '2011;123:2292–2333Other': [316], 'version(s)': [317], 'articleYou': [320], 'are': [321, 675, 968, 1121, 1129, 1430, 1573, 1608, 1612, 1634, 2444, 2491, 2546, 2554, 2642, 2652, 2675, 2894, 3065, 3073, 3083, 3144, 3165, 3175, 3632, 3660, 3679, 3791, 3915, 3932], 'viewing': [322], 'most': [324, 1454, 1513, 1850], 'recent': [325, 520, 1762, 1776, 2061], 'version': [326], 'article.': [329], 'Previous': [330, 335], 'versions:': [331], 'January': [332], '1,': [333], '2011:': [334], 'Version': [336], '1': [337, 1964, 2725, 2790], '1.': [338, 714, 938, 974], 'IntroductionA': [339], 'long-standing': [340], 'association': [341, 1494, 1530, 1568, 1689, 1701, 1898, 1904, 1997, 2095], 'exists': [342], 'between': [343, 656, 732, 1728, 2215, 2288], 'elevated': [344, 1665, 2350, 2368, 2433, 2952], 'triglyceride': [345, 424, 442, 543, 653, 724, 768, 801, 872, 911, 978, 1113, 1127, 1163, 1176, 1210, 1234, 1287, 1529, 1571, 1624, 1648, 1666, 1731, 1767, 1779, 1847, 1879, 1969, 2045, 2059, 2148, 2173, 2191, 2230, 2234, 2253, 2269, 2291, 2303, 2331, 2351, 2369, 2402, 2414, 2502, 2542, 2631, 2667, 2729, 2760, 2827, 2843, 2874, 2910, 2990, 3150, 3329, 3339, 3348, 3465, 3513, 3701], 'levels': [346, 443, 472, 544, 654, 769, 802, 873, 912, 979, 1114, 1128, 1177, 1211, 1542, 1572, 1625, 1732, 2235, 2270, 2292, 2332, 2352, 2415, 2966, 3514], 'cardiovascular': [348, 389, 1462, 1696], 'disease*': [349], '(CVD).1,2': [350], 'However,': [351, 1191, 1682, 1845, 2476, 2945, 3734], 'extent': [353], 'which': [355, 580, 1470, 2136, 2513, 3336, 3357, 3525, 3675, 3801, 3835], 'triglycerides': [356, 387, 492, 1195, 1329, 1362, 1405, 1440, 1708, 1900, 2090, 3827], 'directly': [357, 1710, 3295], 'promote': [358, 3628, 3642, 3860], 'CVD': [359, 499, 592, 643, 1323, 1335, 1407, 1419, 1442, 1536, 1653, 1735, 1786, 1884, 1971, 2098, 2118, 2248, 2278, 2294, 2305, 2356, 2395, 2410, 3398, 3420], 'or': [360, 1474, 1677, 1816, 1870, 1913, 2362, 2761, 3012, 3024, 3040, 3277, 3290, 3414, 3591, 3622, 3626, 3650, 3654, 3726, 3936], 'represent': [361], 'a': [362, 557, 723, 1400, 1532, 1556, 1586, 1616, 1673, 1725, 1781, 1801, 1861, 1896, 2033, 2092, 2218, 2227, 2243, 2285, 2299, 2405, 2422, 2480, 2517, 2601, 2636, 2669, 2879, 2931, 3113, 3122, 3310, 3493, 3578, 3705, 3748, 3758, 3786, 3916], 'biomarker': [363, 2423], 'risk': [365, 390, 500, 604, 644, 1332, 1420, 1443, 1537, 1654, 1697, 1853, 1885, 1962, 2006, 2016, 2036, 2107, 2156, 2192, 2246, 2260, 2306, 3421], 'has': [366, 639, 722, 1337, 1412, 1450, 1796, 3855, 3989], 'been': [367, 404, 1339, 1414, 1452, 1798, 2461, 2816, 3002, 3569, 3596, 3668, 3857, 3991], 'debated': [368], '3': [370, 2626, 2799], 'decades.3': [371], 'To': [372, 3576], 'end,': [374], '2': [375, 461, 793, 1775], 'National': [376, 575, 632, 958, 964, 998, 1059, 1070, 1100, 1296, 1302, 1312], 'Institutes': [377, 959], 'Health': [379, 633, 999, 1060, 1101, 1303, 1313], 'consensus': [380], 'conferences': [381], 'evaluated': [382, 1439, 2027, 2069], 'evidentiary': [384], 'role': [385, 490, 2932, 3974], 'assessment': [391, 2144, 2307], 'provided': [393, 1065, 1291, 2186], 'therapeutic': [394], 'recommendations': [395], 'hypertriglyceridemic': [397, 514, 1617, 3370, 3480, 3549, 3929], 'states.4,5': [398], 'Since': [399], '1993,': [400], 'additional': [401, 1370, 2152, 3477], 'insights': [402], 'have': [403, 444, 473, 741, 1721, 1877, 2185, 2460, 2814, 2947, 3001, 3407, 3568, 3595, 3667, 3902, 3943, 3952], 'made': [405], 'vis-à-vis': [406], 'atherogenicity': [408, 3879], 'triglyceride-rich': [410], 'lipoproteins': [411, 1751, 2459], '(TRLs;': [412], 'ie,': [413], 'chylomicrons': [414, 2613, 2701, 2877], 'very': [416, 692, 763, 1729, 1749, 2863, 2868, 3474], 'low-density': [417, 468, 1750, 1834, 2849, 2852, 2864, 2869, 3468, 3475], 'lipoproteins),': [418], 'genetic': [419, 600], 'metabolic': [421, 598, 1679, 3200], 'regulators': [422], 'metabolism,': [425], 'classification': [427, 668], 'treatment': [429], 'hypertriglyceridemia.': [431, 3435], 'It': [432, 550, 3208], 'is': [433, 482, 551, 710, 1146, 1467, 1479, 1581, 1595, 1660, 1668, 1706, 1768, 2327, 2514, 2587, 2600, 2608, 2730, 2878, 2939, 2951, 2981, 3032, 3104, 3139, 3151, 3226, 3309, 3353, 3482, 3500, 3696, 3703], 'especially': [434, 2426], 'disconcerting': [435], 'that': [436, 1159, 1354, 1438, 1509, 1646, 1663, 1720, 1765, 2141, 2312, 2447, 2520, 2607, 2949, 3000, 3121, 3136, 3211, 3284, 3315, 3369, 3375, 3388, 3424, 3583, 3618, 3627, 3641, 3657, 3700, 3814, 3904, 3920, 3942, 3954], 'United': [439, 626, 629, 1946], 'States,': [440, 630, 1947], 'mean': [441, 467, 1151, 1283], 'risen': [445], 'since': [446], '1976,': [447], 'concert': [449], 'with': [450, 513, 664, 728, 779, 1417, 1485, 1495, 1535, 1540, 1548, 1569, 1576, 1606, 1622, 1695, 1702, 1771, 1788, 1901, 2042, 2052, 2096, 2242, 2250, 2349, 2392, 2429, 2926, 2941, 2997, 3571, 3681, 3762, 3842, 3962], 'growing': [452], 'epidemic': [453], 'obesity,': [455], 'insulin': [456], 'resistance': [457], '(IR),': [458], 'type': [460], 'diabetes': [462, 3797], 'mellitus': [463, 3798], '(T2DM).6,7': [464], 'In': [465, 1820, 1957, 1994, 2195, 2343, 2696, 2710, 2772, 3635, 3754, 3868], 'contrast,': [466], 'lipoprotein': [469, 1426, 1497, 1758, 1835, 1867, 2477, 2583, 2735, 2853, 2856, 2870, 3586, 3604, 3616, 3639], 'cholesterol': [470, 1498, 1814, 2163, 2535, 2641, 3031], '(LDL-C)': [471], 'receded.7': [474], 'Therefore,': [475], 'purpose': [477], 'scientific': [480, 524, 3539], 'statement': [481, 517, 3540], 'update': [484], 'clinicians': [485], 'increasingly': [488], 'crucial': [489], 'evaluation': [495, 1460], 'management': [497], 'highlight': [502], 'approaches': [503], 'aimed': [504], 'at': [505, 784, 1601, 2038, 2078, 2371, 2686], 'minimizing': [506], 'adverse': [508], 'public': [509], 'health–related': [510], 'consequences': [511, 1231, 3433], 'associated': [512, 2241, 2391, 2940, 3570, 3680, 3841, 3891], 'states.': [515], 'This': [516, 1375], 'will': [518, 561, 583, 1738, 2313, 3541, 3873], 'complement': [519], 'statements': [525], 'childhood': [527], 'adolescent': [529], 'obesity8': [530], 'dietary': [532, 2638], 'sugar': [533], 'intake9': [534], 'emphasizing': [536], 'effective': [537], 'lifestyle': [538, 2220, 2310], 'strategies': [539], 'designed': [540], 'lower': [542, 1541, 2044], 'improve': [546], 'overall': [547], 'cardiometabolic': [548], 'health.': [549], 'not': [552, 1130, 1511, 1582, 1635, 1921, 2564, 3173, 3501, 3704], 'intended': [553], 'serve': [555], 'as': [556, 676, 1141, 1561, 1585, 1650, 1800, 1840, 1881, 2404, 2421, 2668, 3008, 3013, 3018, 3071, 3512, 3719, 3727], 'specific': [558, 3585, 3603], 'guideline': [559], 'but': [560, 1558, 2571, 3170], 'be': [562, 587, 1214, 1512, 1739, 2168, 2314, 2751, 2768, 2959, 3131, 3245, 3373, 3381, 3840, 3922], 'value': [564], 'Adult': [567], 'Treatment': [568], 'Panel': [569], 'IV': [570], '(ATP': [571], 'IV)': [572], 'Cholesterol': [576, 965], 'Education': [577, 966], 'Program,': [578], 'from': [579, 1435, 1524, 1874, 1944, 1949, 1953, 2063, 2129, 2180, 2337, 2614, 2992, 3005, 3038, 3075, 3202, 3261, 3286, 3924], 'evidence-based': [581], 'guidelines': [582], 'ensue.': [584], 'Topics': [585], 'addressed': [588], 'include': [589, 2781, 3768], 'epidemiology': [590], 'risk,': [593, 2147, 2357, 2425], 'ethnic': [594], 'racial': [596], 'differences,': [597], 'determinants,': [599, 603], 'family': [602], 'factor': [605, 2407, 2789], 'correlates,': [606], 'effects': [608], 'related': [609, 2325], 'nutrition,': [611], 'physical': [612, 2224, 2465], 'activity,': [613], 'lipid': [615, 1424, 1456, 2338, 2364, 2581], 'medications.2.': [616], 'Scope': [617], 'Problem:': [620], 'Prevalence': [621, 975, 1014, 1083], 'Hypertriglyceridemia': [623, 1017], 'StatesIn': [627], 'Nutrition': [635, 1001, 1062, 1103, 1305, 1315], 'Examination': [636, 1002, 1063, 1104, 1306, 1316], 'Survey': [637, 1003, 1307, 1317], '(NHANES)': [638], 'monitored': [640], 'biomarkers': [641], '>3': [646], 'decades.': [647], 'Accordingly,': [648, 1761], 'increases': [649, 1173, 1193, 1484, 2289, 3522], 'fasting': [651, 767, 977, 1628, 1789], 'serum': [652, 1286], 'observed': [655, 771, 816, 1198], 'surveys': [657], 'conducted': [658], '1976–1980': [660], '1999–20026': [662], 'coincided': [663], 'adjustments': [665], 'hypertriglyceridemia4,10': [670], '(Table': [671, 757], '1).': [672], 'Current': [673], 'designations': [674], 'follows:': [677], '150': [678], '199': [680], 'mg/dL,': [681, 687, 691, 727], 'borderline': [682], 'high;': [683, 688], '200': [684], '499': [686], '≥500': [690, 913], 'high.': [693], 'The': [694, 869, 1345, 1933, 2024, 2125, 2489, 2500, 2743, 3347], 'prevalence': [695, 799, 813, 870, 909], 'hypertriglyceridemia': [697, 1085, 3306], 'ethnicity': [699, 995], 'NHANES': [701, 733, 755, 806, 936, 1035, 1078, 1096, 1098, 1685], '1988–1994': [702, 734, 1247], '1999–2008': [704, 756], 'according': [705], 'these': [707, 1642, 1917, 2346, 3081, 3351, 3693, 3830, 3955, 3969], 'cut': [708, 786], 'points': [709, 787], 'shown': [711, 1122, 3858, 3953, 3992], 'Figure': [713, 792], 'Overall,': [715, 1872, 3254], '31%': [716], 'adult': [719], 'US': [720, 1033, 1241], 'population': [721, 1135, 1391], 'level': [725, 1487, 1649, 1667, 1848, 1880, 2370, 2403], '≥150': [726, 803], 'no': [729, 2122, 2151, 3401], 'appreciable': [730], 'change': [731, 2267], '1999–2008.': [736, 807, 1097], 'Among': [737], 'ethnicities,': [738], 'Mexican': [739, 780, 818, 828, 880, 921, 1052], 'Americans': [740, 781], 'highest': [743, 812, 878, 932, 2394], 'rates': [744, 814], '(34.9%),': [745], 'followed': [746, 835, 894, 2206], 'non-Hispanic': [748, 837, 852, 896], 'whites': [749], '(33%)': [750], 'blacks': [752], '(15.6%)': [753], '2).': [758], 'High': [759], '(≥200': [760], 'mg/dL)': [761, 766, 984, 1184, 1967], 'high': [764, 1233, 1480, 1623, 1730, 2377, 3494], '(≥500': [765], 'were': [770, 815, 1171, 1197, 1826, 2121, 2205, 2212, 2240], '16.2%': [773], '1.1%': [775], 'adults,': [777], 'respectively,': [778], 'being': [782], 'overrepresented': [783], 'both': [785, 1179, 2002, 2097, 2117], '(19.5%': [788], '1.4%,': [790], 'respectively).': [791], 'illustrates': [794], 'sex-': [796], 'age-related': [798], 'mg/dL': [804, 875, 914, 1024], 'Within': [808], 'each': [809], 'group,': [810], 'men': [820, 839, 854, 882, 898, 923, 1180, 1973, 2184, 2198], '(50': [821], '59': [823, 926], 'years': [824, 832, 845, 858, 866, 884, 889, 902, 927, 991, 1092, 1206, 2202, 2275, 2283], 'old,': [825, 833, 846, 859, 867, 903], '58.8%)': [826], 'women': [830, 841, 862, 887, 1186], '(≥70': [831], '50.5%),': [834], 'white': [838, 897, 1278], '(60': [842, 863], '69': [844, 865, 901], '43.6%': [847], '42.2%,': [849], 'respectively)': [850], 'black': [853, 1274], '(40': [855], '49': [857, 1205], '30.4%)': [860], '25.3%).': [868], '≥200': [874], 'was': [876, 915, 1363, 1780, 1860, 1974, 1998, 2127, 2373, 2390], 'also': [877, 2572, 2929, 3183, 3209, 3661, 3810, 3856, 3990], '(≥30': [883], 'old)': [885], '(≥40': [888], 'old;': [890], '21%': [891], '36%),': [893], '(30': [899], '20%': [904], '25%).': [906], 'Although': [907, 3058, 3537, 3776], 'relatively': [916, 2880], 'low': [917, 2380, 2430, 2964], '(1%': [918], '2%),': [920], '50': [924], 'age': [929, 993, 1094, 1201, 2087], 'exhibited': [930, 2353], 'rate': [933], '(9%)': [934], '1999–2008.Table': [937], 'Triglyceride': [939, 1238], 'Classification': [940], 'Revisions': [941], 'Between': [942], '1984': [943], '2001TG': [945], 'Designate1984': [946], 'NIH': [947], 'Consensus': [948], 'Panel1993': [949], 'NCEP': [950, 952], 'Guidelines2001': [951], 'GuidelinesDesirable<250<200<150Borderline-high250–499200–399150–199High500–999400–999200–499Very': [953], 'high>1000>1000≥500TG': [954], 'indicates': [955, 1008, 1058, 1099, 2831, 3438], 'triglyceride;': [956, 3471], 'NIH,': [957], 'Health;': [961], 'NCEP,': [963], 'Program.Values': [967], 'milligrams': [969], 'per': [970, 1963, 2008, 3787], 'deciliter.Download': [971], 'figureDownload': [972, 1080, 2822, 3429], 'PowerPointFigure': [973, 1081, 2823, 3430], '(≥150,': [980], '200,': [981, 1021], '500': [983, 1023], 'males': [986, 1087], '(non-pregnant)': [988], 'females': [989, 1090], '≥18': [990, 1091], '(1988–1994': [1004], '1999–2008).': [1006], 'TG': [1007], 'triglycerides;': [1009, 1107], 'Non-H,': [1010], 'non-Hispanic.Table': [1011], '2.': [1012, 1082], 'Overall': [1013], '(%)': [1015], 'Based': [1018], '150,': [1020], 'Cut': [1025, 1037], 'Points': [1026], 'Age,': [1028, 1246], 'Sex,': [1029], 'Ethnicity': [1031], 'Adults,': [1034], '1999–2008DemographicTriglyceride': [1036], 'Points,': [1038], 'mg/dL≥150≥200≥500Overall': [1039], '(age': [1040], '≥20': [1041, 1243, 1254, 1262], 'y)31.016.21.1Age,': [1042], 'y': [1043], '20–2920.79.50.8': [1044], '30–3925.814.10.7': [1045], '40–4932.816.71.6': [1046], '50–5936.720.11.8': [1047], '60–6941.622.61.0': [1048], '≥7034.517.20.5Sex': [1049], 'Men35.419.81.8': [1050], 'Women*26.812.70.5Ethnicity': [1051], 'American34.919.51.4': [1053], 'Non-Hispanic,': [1054, 1056], 'black15.67.60.4': [1055], 'white33.017.61.1NHANES': [1057], 'Survey.Data': [1064], 'Epidemiology': [1068, 1294, 1319], 'Branch,': [1069, 1295], 'Heart,': [1071, 1297], 'Lung,': [1072, 1298], 'Blood': [1074, 1300], 'Institute.*Excludes': [1075], 'pregnant': [1076, 1289], 'women.Source:': [1077], '1999–2008.Download': [1079], 'non-pregnant': [1089], 'Survey;': [1105], 'TG,': [1106, 3470], 'Non': [1108], 'H,': [1109], 'non-Hispanic;': [1110], 'Mexican-Am,': [1111], 'Mexican-American.Serum': [1112], 'selected': [1116, 3875], 'percentiles': [1117], 'geometric': [1119, 1139, 1282], 'means': [1120], 'Table': [1124], '3.': [1125, 1236, 2824], 'Because': [1126], 'normally': [1131], 'distributed': [1132], '(Section': [1136, 1221, 1481, 2820, 2955], '3.1),': [1137], 'mean,': [1140], 'derived': [1142], 'log': [1144, 1475], 'transformation,': [1145], 'favored': [1147], 'over': [1148, 2271], 'arithmetic': [1150], 'reduce': [1153, 3623], 'potential': [1155], 'impact': [1156, 1711, 3601], 'outliers': [1158], 'might': [1160], 'otherwise': [1161], 'overestimate': [1162], 'levels.11': [1164], 'Over': [1165], 'past': [1167], '20': [1168], 'years,': [1169, 2210], 'there': [1170, 2166, 2211, 3790], 'small': [1172, 2616, 2649], 'median': [1175], '(122': [1181], 'versus': [1182, 1188], '119': [1183], '(106': [1187], '101': [1189], 'mg/dL).': [1190], 'primarily': [1196, 2128, 2366], 'younger': [1200], 'groups': [1202], '(20': [1203], 'old),': [1207], 'overall,': [1209], 'continue': [1212], 'higher': [1215, 2034], 'than': [1216, 1864, 3782], 'less': [1218, 3780], 'industrialized': [1219], 'societies': [1220], '12.1).': [1222], 'We': [1223], 'now': [1224], 'address': [1225, 3542], 'epidemiological': [1227, 1718], 'putative': [1229], 'pathophysiological': [1230, 3579, 3792, 3843], 'levels.Table': [1235], 'Serum': [1237], 'Levels': [1239], 'Adults': [1242], 'Years': [1244], '1999–20081988–19941999–2008Geometric': [1249], 'MeanSelected': [1250, 1252], 'PercentileGeometric': [1251], 'PercentileAge-SpecificAge-Adjusted5th25th50th75th95thAge-SpecificAge-Adjusted5th25th50th75th95thMen': [1253], 'y127.95383119176321128.35285122182361': [1255], '20–2995.1456588126237106.24570100150305': [1256], '30–39118.85279113169298122.15080119175324': [1257], '40–49138.45891133190349143.85794134201473': [1258], '50–59146.66195137223394140.66193133197388': [1259], '60–69146.764101140200378138.25996133196372': [1260], '≥70134.36495131179306121.55487120168266Women*': [1261], 'y109.74772101150274110.04874106155270': [1263], '20–2983.842608411118288.7396383123205': [1264], '30–3991.343628312126795.8426491138243': [1265], '40–49103.04870102139251105.54973102146249': [1266], '50–59129.25584126186325124.75584120176305': [1267], '60–69143.96197137203380135.96396137192299': [1268], '≥70137.27097134182284133.06395129180293Race/ethnicity': [1269], 'Mexican-American': [1270], 'Men138.65383120185387140.85389126196392': [1271], 'Women131.85585118167291126.64881113164277': [1272], 'Non-Hispanic': [1273, 1277], 'Men102.544659214025999.7446794129248': [1275], 'Women88.840587911520888.1386283116209': [1276], 'Men131.35585123182323130.35387126188368': [1279], 'Women110.94874102154276112.15077109161275Percentile': [1280], 'distribution': [1284, 1466], '(mg/dL).*Excludes': [1288], 'women.Data': [1290], 'Institute.Source:': [1301], 'III': [1308], '(1988–1994)': [1309], 'Concurrent': [1311], '(1999–2008).3.': [1318], 'Triglycerides': [1321], 'Risk': [1324, 2066], 'AssessmentThe': [1325], 'independent': [1326, 1359, 1402, 1652, 1883], 'relationship': [1327, 1403, 1508, 1727], 'future': [1334], 'events': [1336], 'long': [1338, 1451], 'controversial.': [1340], 'An': [1341], 'article': [1342], 'published': [1343, 1935], 'New': [1346], 'England': [1347], 'Journal': [1348], 'Medicine': [1350], '1980': [1352], 'concluded': [1353], 'evidence': [1356, 1523, 1763], 'an': [1358, 1505, 1551, 1651, 1664, 1670, 1882, 2628, 2960, 3389, 3528, 3629, 3720, 3728, 3972], 'effect': [1360, 1410, 1552], '“meager,”3': [1364], 'yet': [1365], 'despite': [1366], 'several': [1367], 'decades': [1368], 'research,': [1371], 'controversy': [1373], 'persists.': [1374], 'may': [1376, 1510, 1709, 2167, 2958, 3130, 3372, 3380, 3395, 3741, 3815], 'part': [1378], 'reflect': [1379], 'conflicting': [1380], 'results': [1381, 1434, 1518, 1753, 3285, 3316, 3337, 3358, 3526], 'quality': [1384], 'studies': [1386, 1398, 1437, 1526, 1719, 1876, 1894, 1919, 1940, 2181, 3367], 'performed': [1387], 'general': [1390], 'clinical': [1394, 2335, 3402], 'samples.': [1395], 'Second,': [1396, 1477], 'demonstrating': [1399], 'significant': [1401, 1559, 2213, 3123], 'events,': [1408], 'size': [1411], 'typically': [1413], 'modest': [1415, 1557], 'compared': [1416, 1787, 2041, 2249], 'standard': [1418, 2106], 'factors,': [1421, 2261], 'including': [1422, 2262], 'other': [1423, 2259, 2777, 3543], 'parameters.': [1427], 'Summarized': [1428], 'below': [1429], 'methodological': [1431], 'considerations': [1432], 'representative': [1436], 'assessment.3.1.': [1444], 'Methodological': [1445], 'Considerations': [1446], 'Effect': [1448], 'ModificationTriglyceride': [1449], 'problematic': [1455], 'measure': [1457, 1922, 2172], 'risk.': [1463, 2295, 2396], 'First,': [1464], 'markedly': [1468], 'skewed,': [1469], 'necessitates': [1471], 'categorical': [1472], 'definitions': [1473], 'transformations.': [1476], 'variability': [1478], '10)': [1482], 'triglyceride.12': [1489], 'Third,': [1490], 'strong': [1492, 1726], 'inverse': [1493, 1567], 'high-density': [1496, 3461], '(HDL-C)': [1499], 'apolipoprotein': [1501, 2832, 3439, 3443], '(apo)': [1502], 'AI,': [1503], 'suggests': [1504, 1764], 'intricate': [1506], 'biological': [1507], 'suitably': [1514], 'represented': [1515], 'multivariate': [1520, 1639], 'analysis.': [1521, 1640], 'Finally,': [1522], 'prospective': [1525, 2082], 'supports': [1531, 3556], 'stronger': [1533, 1862], 'link': [1534], 'people': [1539, 2072], 'HDL-C13,14': [1544], 'LDL-C13,14': [1546], 'T2DM.15,16': [1549], 'Such': [1550], 'modification': [1553], 'could': [1554, 3839], 'obscure': [1555], 'effect,': [1560], 'demonstrated': [1562, 3903], 'recently.17In': [1563], 'addition': [1564, 2773], 'HDL-C,': [1570, 2381], 'closely': [1574], 'aligned': [1575], 'T2DM,': [1577], 'even': [1578, 1809, 2255], 'though': [1579], 'T2DM': [1580, 1607, 1633, 2954], 'always': [1583], 'examined': [1584], 'confounding': [1587], 'factor,': [1588], 'when': [1590, 2427, 3141], 'it': [1591, 3555, 3695], 'is,': [1592, 3492], 'diagnosis': [1594], 'commonly': [1596, 2374], 'based': [1597, 2308, 3532], 'history.': [1599], 'Yet': [1600], 'least': [1602], '25%': [1603], 'subjects': [1605, 1621, 1825, 2030, 2348], 'undiagnosed,18': [1609], 'they': [1611, 2719, 2766, 3019, 3072, 3931], 'often': [1613, 1905], 'concentrated': [1614], 'within': [1615, 3350], 'population.': [1618], 'Similarly,': [1619], 'many': [1620, 1891, 2344], 'impaired': [1627], 'glucose': [1629], 'who': [1630, 2204], 'subsequently': [1631, 3161], 'develop': [1632], 'adjusted': [1636], 'Hence,': [1641], 'limitations': [1643], 'restrict': [1644], 'conclusions': [1645], 'support': [1647], 'factor.': [1655], 'Compounding': [1656], 'aforementioned': [1658], 'problem': [1659], 'argument': [1662], 'simply': [1669, 3504], 'epiphenomenon': [1671], '(ie,': [1672, 2385, 3523, 3739, 3934], 'by-product)': [1674], 'IR': [1676, 3308], 'syndrome': [1680], '(MetS).': [1681], 'analysis': [1683, 2004], 'data': [1686, 1873, 2179], 'evaluating': [1687], 'all': [1691, 2815, 2892, 3111, 3174], '5': [1692, 2274, 2282], 'MetS': [1693], 'components': [1694], 'found': [1698, 1895, 2032, 2284], 'strongest': [1700], 'triglycerides.19A': [1703], 'pivotal': [1704], 'consideration': [1705], 'how': [1707], 'atherosclerotic': [1713, 3711], 'process': [1714], 'view': [1716], 'failed': [1722], 'demonstrate': [1724], 'increased': [1734, 2245, 3288, 3324, 3390], 'death.13,20': [1736], 'As': [1737], 'described': [1740], 'Section': [1742], '4,': [1743], 'hydrolysis': [1744, 2875, 3946], 'TRLs': [1746, 3567, 3738, 3756, 3777, 3809, 3854, 3905, 3941], '(eg,': [1747, 2175, 2221, 3551, 3794, 3938, 4000], 'chylomicrons,': [1748, 2662], '[VLDL])': [1752], 'atherogenic': [1755, 2387, 3393, 3486, 3498, 3764], 'cholesterol-enriched': [1756], 'remnant': [1757, 2886, 2934], 'particles': [1759, 2478, 3070, 3164, 3181, 3352, 3379, 3394, 3487, 3499, 3587, 3617, 3640, 3678, 3784, 3831, 3956], '(RLPs).': [1760], 'nonfasting': [1766, 1778], 'strongly': [1769], 'correlated': [1770], 'RLPs,21': [1772], 'studies,': [1777, 1808, 2347, 3566, 3615], 'superior': [1782], 'predictor': [1783], 'incident': [1785, 2277], 'levels.21,223.2.': [1790], 'Case-Control': [1791], 'Studies,': [1792], 'Including': [1793], 'Angiographic': [1794], 'StudiesTriglyceride': [1795], 'routinely': [1797], 'identified': [1799], '“risk': [1802], 'factor”': [1803], 'case-control': [1805, 1822, 1875], 'angiographic': [1807], 'after': [1810, 1908, 1990, 2011, 2103, 2256, 2738, 3088], 'adjustment': [1811, 1909, 1991, 2012, 2085, 2104, 2131, 2257], 'total': [1813, 2162], '(TC)': [1815], 'LDL-C23–34': [1817], 'HDL-C.24,27–29,33,34': [1819], 'another': [1821], 'study,': [1823], 'case': [1824], '3-fold': [1827], 'likely': [1829], 'exhibit': [1831], 'small,': [1832, 3360, 3376], 'dense': [1833, 3361, 3377], '(LDL)': [1836], 'particles,': [1837], 'referred': [1838], '“pattern': [1842], 'B”': [1843], 'phenotype.35': [1844], 'explained': [1849], 'pattern': [1856], 'B': [1857, 3553, 3773], 'phenotype': [1858], 'covariate': [1863], 'LDL-C,': [1865], 'intermediate-density': [1866, 2846], '(IDL)': [1868], 'cholesterol,': [1869, 2496], 'HDL-C.': [1871, 1923, 1993, 2263], 'supported': [1878], 'factor.3.3.': [1886], 'Prospective': [1887], 'Population-Based': [1888], 'Cohort': [1889], 'StudiesAlthough': [1890], 'early': [1892], 'cohort': [1893], 'univariate': [1897, 1958, 2003], 'CVD,': [1902, 3592], 'became': [1906], 'nonsignificant': [1907], 'either': [1911, 3033, 3287], 'TC': [1912, 3508], 'LDL-C.': [1914, 3510], 'Most': [1915], 'earlier': [1918], 'did': [1920], 'Two': [1924], 'meta-analyses': [1925], 'triglycerides-CVD': [1928], 'question': [1929, 2326], 'drew': [1930], 'similar': [1931, 3167], 'conclusions.': [1932], 'first,': [1934], '1996,': [1937], 'considered': [1938, 3633, 3662], '16': [1939], 'men,': [1942], '6': [1943, 1948], 'Scandinavia,': [1950], '4': [1952], 'elsewhere': [1954], 'Europe.36': [1956], 'analysis,': [1959], 'relative': [1961, 2035], 'mmol/L': [1965], '(88.5': [1966], '1.32': [1975], '(95%': [1976, 1984], 'confidence': [1977, 1985, 2019], 'interval': [1978, 1986, 2020], '1.26': [1979], '1.39)': [1981], '1.14': [1983], '1.05': [1987], '1.28)': [1989], 'women,': [1995], 'robust': [2000], '(relative': [2005, 2015], '1.76': [2007], 'mmol/L)': [2009], 'HDL-C': [2014, 2111, 2133, 2160, 2431, 2965], '1.37,': [2017], '95%': [2018, 2666], '1.13': [2021], '1.66).': [2023], 'second': [2025], 'meta-analysis': [2026, 2062], '262': [2028], '000': [2029], '(1.4)': [2037], 'upper': [2040], 'tertile;': [2046], 'estimate': [2048], 'improved': [2049], '1.72': [2051], 'correction': [2053], '“regression': [2055], 'dilution': [2056], 'bias”': [2057], '(intraindividual': [2058], 'variation).2A': [2060], 'Emerging': [2065], 'Factors': [2067], 'Collaboration': [2068], '302': [2070], '430': [2071], 'free': [2073, 2493, 2534, 2746, 2838, 3457], 'known': [2075], 'vascular': [2076, 2146, 2155, 4005], 'disease': [2077], 'baseline': [2079, 2372], '68': [2081], 'studies.17': [2083], 'With': [2084], 'sex,': [2089], 'showed': [2091], 'strong,': [2093], 'stepwise': [2094], 'ischemic': [2100], 'stroke;': [2101], 'however,': [2102, 3400], 'factors': [2108, 3649], 'non–HDL-C,': [2113, 2135], 'associations': [2115], 'stroke': [2120], 'longer': [2123], 'significant.': [2124], 'attenuation': [2126], 'led': [2137], 'conclusion': [2140], '“…for': [2142], 'population-wide': [2143], 'measurement': [2149, 3506], 'provides': [2150, 2627], 'information': [2153, 2420], 'about': [2154], 'given': [2157], 'knowledge': [2158], 'levels,': [2164], 'although': [2165], 'separate': [2169], 'reasons': [2170], 'concentration': [2174, 3495], 'prevention': [2176], 'pancreatitis).”17Additional': [2178], 'involving': [2182], 'young': [2183], 'new': [2187], 'insight': [2188], 'into': [2189, 2644, 2654, 2677, 2759, 2762, 3091], 'status': [2193], 'question.37': [2194], '13': [2196], '953': [2197], '26': [2199], '45': [2201], 'old': [2203], 'up': [2207, 2753, 3004], '10.5': [2209], 'correlations': [2214], 'adoption': [2216], 'favorable': [2219], 'weight': [2222], 'loss,': [2223], 'activity)': [2225], 'decrease': [2228], 'levels.': [2231], 'At': [2232], 'baseline,': [2233], 'top': [2238], 'quintile': [2239], '4-fold': [2244], 'lowest': [2252], 'quintile,': [2254], 'Evaluation': [2264], 'first': [2273], 'next': [2281], 'direct': [2286, 2924], 'correlation': [2287], 'These': [2296, 3664], 'observations': [2297, 3582], 'add': [2298], 'dynamic': [2300], 'element': [2301], 'intervention': [2311], 'elaborated': [2315], 'later': [2317], 'statement.3.4.': [2320], 'Insights': [2321], 'TrialsA': [2324], 'ability': [2329], 'predict': [2334], 'benefit': [2336], 'therapy': [2339], 'outcome': [2341, 3403], 'trials.': [2342], 'improvement': [2354], 'irrespective': [2358], 'drug': [2360], 'class': [2361], 'targeted': [2363], 'fraction,38–40': [2365], 'because': [2367, 3713], 'accompanied': [2375], 'LDL-C': [2378, 3427, 3531], 'combination': [2384, 2994], 'dyslipidemic': [2388], 'triad)': [2389], 'Taken': [2397], 'together,': [2398], 'independence': [2400], 'causal': [2406], 'promoting': [2409], 'remains': [2411], 'debatable.': [2412], 'Rather,': [2413], 'appear': [2416], 'provide': [2418, 3577], 'unique': [2419, 3812], 'combined': [2428], 'LDL-C.4.': [2434], 'Pathophysiology': [2435], 'Hypertriglyceridemia4.1.': [2437], 'Normal': [2438], 'Metabolism': [2439], 'TRLs4.1.1.': [2441], 'Lipoprotein': [2442, 3896], 'CompositionLipoproteins': [2443], 'macromolecular': [2445], 'complexes': [2446], 'carry': [2448], 'various': [2449], 'lipids': [2450, 2490, 2570, 3143], 'proteins': [2452, 2556, 2798], 'plasma.41': [2454], 'Several': [2455], 'major': [2456], 'classes': [2457], 'defined': [2462], 'their': [2464, 2471, 3089], 'chemical': [2467], 'characteristics,': [2468], 'particularly': [2469], 'flotation': [2472], 'characteristics': [2473], 'during': [2474], 'ultracentrifugation.': [2475], 'form': [2479, 2603, 3053], 'continuum,': [2481], 'varying': [2482], 'composition,': [2484], 'size,': [2485], 'density,': [2486], 'function.': [2488], 'mainly': [2492, 2522, 3047, 3247], 'esterified': [2495], 'triglycerides,': [2497], 'phospholipids.': [2499], 'hydrophobic': [2501, 2526], 'cholesteryl': [2504, 3332, 3446, 3449], 'esters': [2505], '(CEs)': [2506], 'compose': [2507], 'core': [2509, 2550, 2569, 2656, 2728], 'lipoproteins,': [2512, 3046], 'covered': [2515], 'unilamellar': [2518], 'surface': [2519, 2559, 3055, 3233], 'contains': [2521], 'amphipathic': [2524], '(both': [2525], 'hydrophilic)': [2528], 'phospholipids': [2529, 3052], 'smaller': [2531, 3156], 'amounts': [2532], 'proteins.': [2537], 'Hundreds': [2538], 'thousands': [2540], 'CE': [2544, 3781], 'molecules': [2545, 3082], 'carried': [2547], 'different': [2552], 'lipoproteins.Apolipoproteins': [2553], 'lipoproteins.': [2562], 'They': [2563, 3767], 'only': [2565], 'participate': [2566], 'solubilizing': [2568], 'play': [2573, 3112, 3218, 3971], 'critical': [2574], 'roles': [2575, 3220], 'regulation': [2578], 'plasma': [2580, 3006, 3242, 3262, 3927], 'transport.': [2584], 'Apo': [2585, 2598, 2623, 2829, 2916, 2975, 3049, 3224, 3436, 3441, 3850], 'B100': [2586, 2606, 3050, 3129, 3225], 'required': [2588, 2609], 'secretion': [2591, 2611, 3098, 3134], 'hepatic-derived': [2593], 'VLDL,': [2594, 2862, 3473], 'IDL,': [2595, 2845], 'LDL.': [2597, 3189, 3207, 3753], 'B48': [2599], 'truncated': [2602], 'apo': [2605, 2703, 2705, 2708, 2741, 2775, 2782, 2784, 2793, 2883, 3128, 3212, 3552, 3772], 'intestine.4.2.': [2617], 'Transport': [2618, 2970], 'Dietary': [2620], 'Lipids': [2621, 2973], 'B48–Containing': [2624], 'LipoproteinsFigure': [2625], 'overview': [2629], 'metabolism.': [2632, 2828, 3302], 'After': [2633], 'ingestion': [2634], 'meal,': [2637], 'fat': [2639, 2755], 'absorbed': [2643], 'cells': [2646, 2756, 3970], 'intestine': [2650], 'incorporated': [2653], 'nascent': [2658, 3068], 'chylomicrons.': [2659], 'Newly': [2660], 'formed': [2661], 'representing': [2663], '80%': [2664, 3257], 'percentage': [2670], 'composition': [2672, 3300, 3413], 'lipids,41': [2674], 'secreted': [2676, 3074], 'lymphatic': [2679], 'system': [2680], 'then': [2682], 'enter': [2683], 'circulation': [2685], 'junction': [2688], 'internal': [2691], 'jugular': [2692], 'subclavian': [2694], 'veins.': [2695], 'lymph': [2698], 'blood,': [2700], 'acquire': [2702], 'CII,': [2704, 2776, 3061], 'CIII,': [2706, 3062], 'E.': [2709], 'capillary': [2712], 'beds': [2713, 3838], 'adipose': [2715], 'tissue': [2716, 3272], 'muscle,': [2718], 'bind': [2720], 'glycosylphosphatidylinositol-anchored': [2722], 'HDL-binding': [2723], 'protein': [2724, 3230], '(GPIHBP1),42': [2726], 'hydrolyzed': [2731, 3152, 3354], 'enzyme': [2734], 'lipase': [2736, 2787, 2911], '(LPL)': [2737], 'activation': [2739], 'CII.43': [2742], 'lipolytic': [2744], 'products,': [2745], 'fatty': [2747, 2839, 2998, 3010, 3458, 3833], 'acids': [2748, 2999, 3011, 3015], '(FFAs),': [2749], 'can': [2750, 2767, 3182, 3803, 3906, 3921, 3957], 'taken': [2752, 3003], 'reincorporated': [2758], 'muscle': [2763], 'cells,': [2764], 'where': [2765], 'used': [2769, 3669], 'energy.': [2771], 'activators': [2778], 'LPL': [2780, 3191, 3824], 'AIV,44': [2783], 'AV,45': [2785], 'maturation': [2788], '(LMF1),46': [2791], 'whereas': [2792, 3269], 'CIII47': [2794], 'angiopoietin-like': [2796], '(ANGPTL)': [2797], '448': [2801], 'inhibit': [2802], 'LPL.': [2803, 3948], 'Human': [2804], 'mutations': [2805], 'LPL,': [2807, 2855, 3154], 'APOC2,': [2808], 'GPIHBP1,': [2809], 'ANGPTL3,': [2810], 'ANGPTL4,': [2811], 'APOA5': [2813], 'implicated': [2817], 'chylomicronemia': [2819], '5).Download': [2821], 'Overview': [2825], 'A-V': [2830], 'A-V;': [2833], 'CMR,': [2834], 'chylomicron': [2835, 2885], 'remnant;': [2836], 'FFAs,': [2837], 'acids;': [2840], 'HTGL,': [2841, 3214, 3356, 3463], 'hepatic': [2842, 2909, 2919, 3142, 3464], 'lipase;': [2844, 2857, 3466], 'lipoprotein;': [2847, 2850, 2865, 3462, 3469], 'LDL,': [2848, 3235, 3467], 'LDL-R,': [2851], 'receptor;': [2854], 'LRP,': [2858], 'LDL': [2859, 2903, 2906, 3216, 3240, 3252, 3259, 3266, 3297, 3342, 3362, 3378, 3677, 3765, 3783], 'receptor–related': [2860, 2907], 'protein;': [2861, 3452], 'VLDL-R,': [2867], 'receptor.The': [2871], 'consequence': [2872, 3311], 'CE-': [2881], 'E–enriched': [2884], '(CMR).': [2887], 'Under': [2888], 'physiological': [2889], 'conditions,': [2890], 'essentially': [2891, 3227], 'CMRs': [2893, 2922], 'removed': [2895, 3176], 'liver': [2898, 3037, 3044, 3103, 3118, 3322], 'binding': [2900], 'receptor,': [2904], 'protein,': [2908, 3335], '(HTGL),': [2912], 'cell-surface': [2914], 'proteoglycans.49–51': [2915], 'AV': [2917], 'facilitates': [2918], 'clearance': [2920], 'through': [2923, 3426], 'interaction': [2925], 'SorLA.52': [2927], 'HTGL': [2928, 2937, 2950], 'plays': [2930], 'removal,49': [2935], 'deficiency': [2938], 'reduced': [2942], 'RLP': [2943], 'clearance.': [2944], 'studies53': [2946], 'indicated': [2948], '6)': [2956], 'important': [2961, 3219, 3697, 3973], 'contributor': [2962], 'disease.4.3.': [2969], 'Endogenous': [2972], 'B100–Containing': [2976], 'Lipoproteins4.3.1.': [2977], 'Very': [2978], 'Low-Density': [2979], 'LipoproteinsVLDL': [2980], 'assembled': [2982], 'endoplasmic': [2985], 'reticulum': [2986], 'hepatocytes.': [2988], 'VLDL': [2989, 3030, 3069, 3087, 3100, 3149, 3159, 3203, 3325, 3328, 3521, 3939], 'derives': [2991], 'glycerol': [2996], '(either': [3007], 'albumin-bound': [3009], 'triglyceride–fatty': [3014], 'RLPs': [3017, 3914], 'return': [3020], 'liver)': [3023], 'newly': [3025, 3126], 'synthesized': [3026, 3034, 3127], 'liver.': [3029, 3179], 'acetate': [3039], 'delivered': [3041], 'CMRs.': [3048], 'VLDL.': [3057], 'apos': [3059], 'CI,': [3060], 'E': [3064], 'present': [3066], 'hepatocyte,': [3077], 'majority': [3079], 'probably': [3084], 'added': [3085], 'entry': [3090], 'plasma.': [3092], 'Regulation': [3093], 'assembly': [3096], 'complex;': [3105], 'substrates,': [3106], 'hormones,': [3107], 'neural': [3109], 'signals': [3110], 'role.': [3114], 'Studies': [3115], 'cultured': [3117], 'cells51,54': [3119], 'indicate': [3120], 'proportion': [3124, 3517], 'degraded': [3132], 'before': [3133], 'degradation': [3138], 'inhibited': [3140], 'abundant.54Once': [3145], 'plasma,': [3148], 'generating': [3155], 'denser': [3158], 'IDL.': [3162], 'IDL': [3163, 3180, 3205], 'physiologically': [3166], 'CMRs,': [3169, 3172], 'unlike': [3171], 'undergo': [3184], 'further': [3185], 'catabolism': [3186, 3260, 3292], 'become': [3188, 3804], 'Some': [3190], 'activity': [3192], 'appears': [3193, 3210, 3243], 'necessary': [3194], 'normal': [3196], 'functioning': [3197], 'cascade': [3201], 'E,': [3213], 'receptors': [3217], 'process.': [3223], 'sole': [3229], 'lifetime': [3238], 'determined': [3246, 3408], 'availability': [3250], 'receptors.': [3253], '≈70%': [3255], 'occurs': [3263, 3274], 'via': [3264], 'receptor': [3267], 'pathway,': [3268], 'remaining': [3271], 'uptake': [3273], 'nonreceptor': [3276], 'alternative-receptor': [3278], 'pathways.41,534.4.': [3279], 'Metabolic': [3280, 3432], 'Consequences': [3281], 'HypertriglyceridemiaHypertriglyceridemia': [3283], 'production': [3289], 'decreased': [3291], 'TRL': [3294, 3881, 3919, 3987], 'influences': [3296], 'HDL': [3299, 3344, 3364, 3371], 'For': [3303, 3611, 3819], 'example,': [3304, 3612, 3820], 'adipocyte': [3313], 'lipolysis': [3314], 'FFA': [3318], 'flux': [3319], 'secretion.': [3326], 'Higher': [3327], 'output': [3330], 'activates': [3331], 'ester': [3333, 3450], 'transfer': [3334, 3451], 'enrichment': [3340], '(Figure': [3345], '4).': [3346], 'content': [3349], 'particles.': [3365, 3766], 'Experimental': [3366], 'suggest': [3368], 'dysfunctional,55,56': [3374], 'susceptible': [3383], 'oxidative': [3385], 'modification,57,58': [3386], 'number': [3391, 3418, 3759, 3898], 'adversely': [3396], 'influence': [3397], 'risk59;': [3399], 'trials': [3404], 'date': [3406], 'whether': [3409], 'normalization': [3410], 'particle': [3412, 3417, 3788], 'reduction': [3415, 3422], 'optimizes': [3419], 'beyond': [3423], 'achieved': [3425], 'lowering.Download': [3428], '4.': [3431], 'A-I': [3437], 'A-I;': [3440], 'B-100,': [3442], 'B-100;': [3444], 'CE,': [3445], 'ester;': [3447], 'CETP,': [3448], 'DGAT,': [3453], 'diacylglycerol': [3454], 'acyltransferase;': [3455], 'FFA,': [3456, 3717], 'acid;': [3459], 'HDL,': [3460], 'lipoprotein.An': [3476], 'complication': [3478], 'states': [3481, 3793], 'accurate': [3483], 'quantification': [3484, 3558], 'circulation.': [3490], 'That': [3491], 'circulating': [3497], 'reliably': [3502], 'assessed': [3503], 'and/or': [3509], 'Moreover,': [3511], 'increase,': [3515], 'triglyceride/CE': [3519], '>5:1),': [3524], 'underestimation': [3529], 'Friedewald': [3535], 'formula.60': [3536], 'variables': [3544], 'consider': [3546, 3874], 'patient': [3550], 'levels),': [3554], 'non–HDL-C.60,614.5.': [3560], 'Atherogenicity': [3561], 'TRLsIn': [3563], 'human': [3564, 3589, 3710], 'observational': [3565], 'measures': [3572], 'coronary': [3574], 'atherosclerosis.62': [3575], 'underpinning': [3580], 'relate': [3584], 'atherosclerosis': [3590, 3682], 'experimental': [3593, 3665, 3900], 'models': [3594, 3889], 'developed': [3597], 'investigate': [3599], 'fractions': [3605], 'isolated': [3607, 3911, 3923], 'vessel': [3608, 3983], 'wall': [3609, 3984], 'cells.': [3610, 3849, 3867, 3913], 'macrophage-based': [3614], 'increase': [3619, 3644, 3994], 'sterol': [3620, 3624], 'delivery': [3621], 'efflux': [3625], 'inflammatory': [3630], 'response': [3631, 3979], 'atherogenic.': [3634, 3663], 'endothelial': [3636, 3848, 3866, 3887, 3912, 3966], 'cell': [3637, 3745, 3888, 4006], 'models,': [3638], 'inflammation,': [3643], 'expression': [3646, 3996], 'coagulation': [3648], 'leukocyte': [3651], 'adhesion': [3652, 4003, 4007], 'molecules,': [3653], 'impair': [3655], 'responses': [3656, 3844, 3862, 3909], 'produce': [3658, 3907], 'vasodilation': [3659], 'systems': [3666, 3901], 'understand': [3671], 'mechanisms': [3673], 'modified': [3676, 3752], 'humans': [3684], 'animals.When': [3687], 'one': [3688], 'evaluates': [3689], 'usefulness': [3691], 'systems,': [3694], 'recognize': [3699], 'overload': [3702], 'classic': [3706, 3763], 'pathological': [3707], 'feature': [3708], 'lesions,': [3712], 'end': [3715], 'product,': [3716], 'serves': [3718], 'active': [3721], 'energy': [3722], 'source': [3723], 'myocytes': [3725], 'inactive': [3729], 'fuel': [3730], 'reserve': [3731], 'adipocytes.': [3733], 'by-product': [3736, 3917], 'RLPs)': [3740], 'lead': [3742], 'foam': [3744], 'formation63': [3746], 'manner': [3749], 'analogous': [3750], 'addition,': [3755], 'share': [3757], 'constituents': [3761, 3813], 'presence': [3770], 'CE.': [3775], 'contain': [3778], 'much': [3779], 'basis,': [3789], 'poorly': [3795], 'controlled': [3796], '[DM])': [3799], 'CEs': [3802], 'enriched': [3805], 'fraction.': [3808], 'possess': [3811], 'contribute': [3816], 'atherogenicity.': [3818], 'action': [3822], 'contained': [3828, 3852], 'releases': [3832], 'acid,': [3834], 'microcapillary': [3837], 'macrophages': [3846, 3864], 'CIII': [3851], 'proatherogenic': [3861, 3908], 'following': [3870], 'paragraphs,': [3871], 'we': [3872], 'aspects': [3876], 'using': [3882], 'vitro': [3884], 'macrophage': [3885], 'vivo': [3893, 3982], 'correlates.4.5.1.': [3894], 'Remnant': [3895], 'ParticlesA': [3897], 'postprandial': [3926], 'subjects;': [3930], 'intestinal': [3933], 'CMRs)': [3935], 'liver-derived': [3937], 'remnants)': [3940], 'undergone': [3944], 'partial': [3945], 'Liu': [3949], 'et': [3950], 'al64': [3951], 'accelerate': [3958], 'senescence': [3959], 'interfere': [3961], 'function': [3964], 'progenitor': [3967], 'cells;': [3968], 'organismal': [3977], 'reparative': [3978], 'injury.': [3985], 'Postprandial': [3986], '(ppTG)': [3988], 'proinflammatory': [3998], 'genes': [3999], 'interleukin-6,': [4001], 'intercellular': [4002], 'molecule-1,': [4004, 4008], 'monocyte': [4010], 'chemotactic': [4011], 'protein-1),65': [4012], 'induce': [4013], 'apoptosis,66': [4014], 'accentuate': [4016], 'infla': [4018]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2036747551', 'counts_by_year': [{'year': 2024, 'cited_by_count': 92}, {'year': 2023, 'cited_by_count': 94}, {'year': 2022, 'cited_by_count': 126}, {'year': 2021, 'cited_by_count': 124}, {'year': 2020, 'cited_by_count': 117}, {'year': 2019, 'cited_by_count': 121}, {'year': 2018, 'cited_by_count': 122}, {'year': 2017, 'cited_by_count': 161}, {'year': 2016, 'cited_by_count': 149}, {'year': 2015, 'cited_by_count': 148}, {'year': 2014, 'cited_by_count': 162}, {'year': 2013, 'cited_by_count': 158}, {'year': 2012, 'cited_by_count': 75}], 'updated_date': '2024-12-18T07:13:13.786073', 'created_date': '2016-06-24'}