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2724, 2739, 2804, 2817, 2829, 2833, 2966, 2977, 2983, 3069, 3081, 3151, 3250, 3309, 3404, 3417, 3423, 3431, 3468, 3476, 3645, 3650, 3766, 3799, 3832, 3910, 3953, 3959, 3970, 4003, 4175, 4185, 4240, 4423], 'a': [37, 173, 302, 686, 853, 1210, 1302, 1321, 1430, 1497, 1638, 2027, 2108, 2329, 2368, 2558, 2650, 2711, 2717, 2884, 3266, 3348, 3413, 3433, 3484, 3489, 3877, 3928, 3954, 4179, 4428, 4547], 'crucial': [38, 1259, 2944], 'enzyme': [39, 265, 2371, 3765, 3957, 4092], 'in': [40, 71, 78, 287, 313, 340, 364, 368, 375, 387, 422, 503, 543, 549, 572, 575, 591, 700, 735, 790, 794, 830, 839, 888, 911, 916, 924, 970, 1004, 1014, 1049, 1148, 1156, 1177, 1222, 1260, 1265, 1320, 1367, 1378, 1485, 1489, 1499, 1507, 1547, 1614, 1650, 1690, 1801, 1860, 1918, 1928, 1932, 1963, 1998, 2036, 2049, 2077, 2134, 2151, 2164, 2181, 2276, 2284, 2303, 2316, 2340, 2342, 2373, 2395, 2426, 2431, 2470, 2511, 2526, 2566, 2570, 2639, 2720, 2725, 2742, 2771, 2774, 2795, 2800, 2952, 2968, 3044, 3058, 3061, 3109, 3152, 3163, 3187, 3238, 3260, 3265, 3314, 3354, 3359, 3395, 3481, 3534, 3579, 3607, 3633, 3659, 3719, 3730, 3778, 3782, 3838, 3840, 3880, 3887, 3924, 3961, 3981, 4004, 4013, 4020, 4054, 4104, 4133, 4193, 4211, 4255, 4259, 4292, 4299, 4308, 4313, 4324, 4414, 4425, 4434, 4445, 4453, 4478, 4490, 4542, 4550, 4556], 'the': [41, 48, 57, 76, 83, 89, 97, 100, 262, 278, 288, 314, 341, 369, 376, 394, 399, 415, 423, 507, 537, 573, 576, 601, 694, 697, 701, 727, 733, 765, 779, 791, 795, 822, 831, 840, 848, 889, 894, 897, 904, 908, 917, 946, 953, 971, 974, 1001, 1005, 1015, 1050, 1144, 1149, 1169, 1174, 1206, 1266, 1299, 1326, 1351, 1358, 1368, 1374, 1425, 1435, 1439, 1443, 1448, 1490, 1500, 1508, 1543, 1552, 1581, 1588, 1603, 1609, 1619, 1623, 1654, 1683, 1692, 1793, 1865, 1921, 1925, 1929, 1957, 1961, 1996, 2030, 2034, 2044, 2078, 2171, 2187, 2231, 2237, 2242, 2272, 2277, 2285, 2304, 2343, 2355, 2362, 2374, 2377, 2387, 2399, 2420, 2427, 2456, 2471, 2479, 2514, 2527, 2567, 2571, 2593, 2609, 2618, 2631, 2640, 2645, 2659, 2721, 2728, 2731, 2734, 2772, 2775, 2788, 2796, 2807, 2811, 2842, 2872, 2948, 2953, 3016, 3022, 3037, 3041, 3045, 3059, 3074, 3077, 3094, 3166, 3173, 3233, 3248, 3254, 3295, 3303, 3320, 3355, 3390, 3393, 3401, 3424, 3466, 3479, 3521, 3637, 3640, 3653, 3660, 3664, 3675, 3680, 3686, 3713, 3720, 3745, 3763, 3769, 3772, 3779, 3790, 3841, 3861, 3866, 3874, 3914, 3920, 3925, 3933, 3940, 3962, 3974, 3982, 4007, 4014, 4017, 4021, 4117, 4152, 4158, 4161, 4176, 4246, 4249, 4253, 4293, 4309, 4314, 4320, 4325, 4357, 4415, 4420, 4435, 4446, 4449, 4476, 4491, 4538, 4551], 'control': [42, 1253], 'of': [43, 52, 59, 111, 255, 264, 281, 297, 311, 372, 396, 401, 417, 440, 500, 689, 781, 891, 900, 907, 948, 973, 1143, 1151, 1216, 1219, 1301, 1304, 1325, 1354, 1361, 1442, 1451, 1503, 1505, 1545, 1593, 1611, 1622, 1627, 1640, 1653, 1707, 1726, 1737, 1799, 1867, 2029, 2082, 2111, 2213, 2300, 2358, 2376, 2401, 2422, 2429, 2458, 2473, 2481, 2561, 2620, 2635, 2647, 2661, 2663, 2733, 2768, 2778, 2791, 2798, 2810, 2824, 2877, 2882, 2950, 3019, 3047, 3052, 3063, 3076, 3172, 3232, 3257, 3319, 3392, 3412, 3483, 3520, 3655, 3663, 3677, 3688, 3774, 3863, 3868, 3876, 3917, 3919, 3935, 3945, 3949, 3964, 3985, 4011, 4016, 4120, 4164, 4172, 4182, 4305, 4356, 4417, 4448, 4457, 4540, 4553], 'homeostasis.': [45], 'It': [46, 91, 844, 930, 1138, 1784, 2023, 2347, 2803, 2955, 3080, 3416, 3649, 3909, 3969, 4079, 4239], 'catalyzes': [47], 'last': [49], 'biochemical': [50], 'reaction': [51], 'gluconeogenesis': [53, 1230, 2341, 2668, 2799, 2951, 2960, 2971, 3057, 3656, 3750, 4291, 4318], 'and': [54, 65, 99, 392, 446, 509, 536, 568, 578, 603, 608, 1017, 1043, 1316, 1344, 1363, 1371, 1373, 1438, 1584, 1590, 1625, 1644, 1716, 1724, 1734, 1990, 2080, 2215, 2228, 2268, 2333, 2384, 2404, 2412, 2518, 2569, 2626, 2637, 2654, 2665, 2783, 2793, 2963, 2974, 3001, 3054, 3088, 3430, 3569, 3669, 3712, 3858, 3865, 3948, 4093, 4154, 4191, 4384, 4483], 'glycogenolysis,': [55], 'i.e.': [56, 826, 1721, 4090], 'hydrolysis': [58], '6-phosphate': [61], '(Glc-6-P)': [62], 'into': [63, 88, 2219, 2282, 2417, 2523, 3035], 'Pi.': [66], 'Glc-6-Pase': [67, 112, 171, 250, 256, 272, 312, 373, 397, 420, 441, 501, 540, 566, 585, 690, 782, 824, 859, 1002, 1041, 1162, 1262, 1292, 1426, 1506, 1546, 1594, 2112, 2792, 2827, 2940, 3946, 4410, 4433, 4451, 4482, 4541], 'therefore': [69], 'unique': [70, 2967], 'that': [72, 96, 176, 565, 778, 847, 855, 934, 967, 1141, 1225, 1251, 1307, 1789, 1920, 2026, 2223, 2350, 2516, 2730, 2806, 2939, 2959, 2984, 3302, 3389, 3411, 3420, 3487, 3652, 3771, 3913, 3958, 3973, 4084, 4178, 4245, 4290, 4317, 4409, 4441, 4474, 4479], 'it': [73, 80, 935, 1012, 1701, 1710, 2157, 2389, 2976, 3298, 3644], 'confers': [74], 'upon': [75], 'tissues': [77, 107, 448, 504, 594, 927], 'which': [79, 300, 763, 949, 1356, 1550, 1587, 2270, 2887, 3516, 3987], 'expressed': [82, 730, 915, 942, 969, 1366, 3777, 4489], 'capacity': [84, 104], 'to': [85, 335, 362, 414, 696, 732, 896, 913, 938, 951, 1173, 1298, 1350, 1482, 1487, 1542, 1583, 1864, 2408, 2463, 2552, 2612, 2624, 2836, 3387, 3406, 3470, 3478, 3636, 3647, 3785, 3792, 3939, 3991, 4150, 4157], 'release': [86, 1624, 1791, 1923, 1958, 3867], 'blood.': [90], 'has': [92, 494, 931, 1617, 1633, 1785, 2158, 2460, 2710, 2786, 3262, 3299, 3488, 4080], 'long': [93, 3881], 'been': [94, 379, 932, 1634, 1787, 2160, 2461, 3263, 3300, 4082], 'recognized': [95], 'liver': [98, 342, 508, 796, 841, 1016, 2081, 2428, 2572, 3249, 3258, 3467, 3638, 3681, 3941, 4159, 4254], 'kidney': [101, 510, 1018, 1655, 3234, 4247], 'possess': [102], 'this': [103, 244, 388, 919, 1536, 1630, 2050, 2482, 2801, 3827, 4173, 4543], 'because': [105, 3662, 3795], 'both': [106, 1310, 1434, 2402, 2888, 2985, 3086, 3567, 3860], 'express': [108, 1551, 3517], 'high': [109, 295, 2116, 3518, 3522], 'levels': [110, 296, 336, 3519], '(1Ashmore': [113, 183], 'J.': [114, 161, 184, 231, 349, 463, 665, 716, 985, 1092, 1192, 1232, 1406, 1407, 1563, 1564, 1669, 1753, 1818, 1883, 1980, 2098, 2857, 2906, 3125, 3203, 3219, 3275, 3368, 3848, 3902, 4036, 4227, 4271, 4339, 4394], 'Weber': [115, 185], 'G.': [116, 159, 186, 229, 460, 512, 552, 612, 641, 673, 704, 746, 806, 1020, 1064, 1080, 1123, 1194, 1277, 1464, 1521, 1741, 1774, 1806, 1839, 1904, 1946, 1968, 2013, 2063, 2086, 2201, 2255, 2445, 2499, 2540, 2582, 2680, 2699, 2755, 2845, 2894, 2927, 3702, 4024, 4341, 4390, 4503, 4527], 'Vitam.': [117, 187], 'Horm.': [118, 188], '1959;': [119, 189], '17:': [120, 190], '91-132Crossref': [121, 191], 'Scopus': [122, 139, 154, 167, 192, 209, 224, 237, 331, 356, 434, 490, 528, 628, 652, 722, 757, 817, 878, 990, 1036, 1075, 1098, 1134, 1200, 1245, 1288, 1339, 1395, 1419, 1474, 1531, 1576, 1675, 1759, 1780, 1824, 1845, 1889, 1910, 1952, 1986, 2019, 2069, 2104, 2207, 2261, 2451, 2505, 2546, 2588, 2686, 2705, 2761, 2863, 2912, 2933, 3146, 3225, 3287, 3343, 3380, 3446, 3462, 3507, 3558, 3628, 3708, 3819, 3854, 4042, 4075, 4283, 4347, 4380, 4405, 4514, 4533], '(104)': [123, 193], 'Google': [124, 141, 156, 169, 194, 211, 226, 239, 333, 358, 436, 473, 492, 530, 630, 654, 680, 724, 759, 819, 880, 992, 1038, 1077, 1100, 1136, 1202, 1247, 1290, 1341, 1397, 1421, 1476, 1533, 1578, 1677, 1761, 1782, 1826, 1847, 1891, 1912, 1954, 1988, 2021, 2071, 2106, 2209, 2263, 2326, 2453, 2507, 2548, 2590, 2688, 2707, 2763, 2865, 2914, 2935, 3119, 3135, 3148, 3197, 3213, 3227, 3289, 3345, 3382, 3448, 3464, 3509, 3544, 3560, 3589, 3617, 3630, 3710, 3740, 3821, 3856, 3907, 4044, 4064, 4077, 4114, 4143, 4221, 4237, 4285, 4349, 4382, 4407, 4516, 4535], 'Scholar,': [125, 142, 157, 195, 212, 227, 474, 631, 655, 1078, 1398, 1762, 1827, 1892, 2689, 2915, 3120, 3136, 3198, 3214, 3449, 3545, 3618, 4045, 4065, 4222, 4517], '2Nordlie': [126, 196], 'R.C.': [127, 197, 428, 2126], 'Foster': [128, 198], 'J.D.': [129, 199], 'Lange': [130, 200], 'A.J.': [131, 201], 'Annu.': [132, 202, 1332], 'Rev.': [133, 203, 1240, 1333], 'Nutr.': [134, 204], '1999;': [135, 205, 643, 748, 808, 1066, 1125, 1279, 1671, 1885, 4505], '19:': [136, 206], '379-406Crossref': [137, 207], 'PubMed': [138, 153, 166, 208, 223, 236, 330, 355, 433, 472, 489, 527, 627, 651, 721, 756, 816, 877, 989, 1035, 1074, 1097, 1133, 1199, 1244, 1287, 1338, 1394, 1418, 1473, 1530, 1575, 1674, 1758, 1779, 1823, 1844, 1888, 1909, 1951, 1985, 2018, 2068, 2103, 2206, 2260, 2450, 2504, 2545, 2587, 2685, 2704, 2760, 2862, 2911, 2932, 3134, 3145, 3212, 3286, 3342, 3379, 3445, 3461, 3506, 3557, 3627, 3707, 3818, 4041, 4074, 4236, 4282, 4346, 4379, 4404, 4513, 4532], '(437)': [140, 210], '3Adrogue': [143, 213], 'H.J.': [144, 214], 'Kidney': [145, 215], 'Int.': [146, 216], '1992;': [147, 217, 1241], '42:': [148, 218], '1266-1282Abstract': [149, 219], 'Full': [150, 220, 469, 646, 648, 751, 753, 811, 813, 1069, 1071, 1128, 1130, 1282, 1284, 1413, 1415, 1570, 1572, 3131, 3209, 3281, 3283, 3374, 3376, 3458, 3503, 3554, 4233, 4277, 4279, 4399, 4401, 4508, 4510], 'Text': [151, 221, 470, 647, 649, 752, 754, 812, 814, 1070, 1072, 1129, 1131, 1283, 1285, 1414, 1416, 1571, 1573, 3132, 3210, 3282, 3284, 3375, 3377, 3459, 3504, 3555, 4234, 4278, 4280, 4400, 4402, 4509, 4511], 'PDF': [152, 222, 471, 650, 755, 815, 1073, 1132, 1286, 1417, 1574, 3133, 3211, 3285, 3378, 3460, 3505, 3556, 4235, 4281, 4403, 4512], '(86)': [155, 225], '4Mithieux': [158, 228], 'Eur.': [160, 230], 'Endocrinol.': [162, 232], '1997;': [163, 233, 560, 874], '136:': [164, 234], '137-145Crossref': [165, 235], '(103)': [168, 238], 'Scholar).': [170, 240, 359, 437, 531, 681, 760, 820, 881, 1039, 1101, 1137, 1203, 1248, 1291, 1342, 1422, 1477, 1534, 1579, 1678, 1783, 1848, 1913, 2022, 2072, 2145, 2210, 2264, 2454, 2508, 2549, 2591, 2708, 2764, 2866, 2936, 3149, 3228, 3290, 3383, 3510, 3561, 3590, 3631, 3822, 3908, 4078, 4115, 4144, 4238, 4286, 4350], 'hydrophobic': [174], 'protein': [175, 569, 920], 'embedded': [178], 'within': [179, 3400], 'endoplasmic': [180, 849, 975], 'reticulum': [181, 850, 976], 'membrane': [182, 851], 'The': [241, 438, 882, 2981, 3049, 3229, 3760, 3823, 4302, 4351], 'reason': [242, 2982], 'for': [243, 858, 957, 994, 1712, 2236, 2382, 2398, 2658, 2667, 2736, 2875, 2947, 3005, 3013, 3040, 3073, 3351, 3473, 3493, 3679, 3922, 4431], 'localization': [245], 'not': [247, 588, 1155, 1687, 2159, 2280, 2299, 2521, 2740, 2830, 2834, 3800], 'clear.': [248], 'Before': [249], 'cDNA': [251], 'was': [252, 259], 'isolated,': [253], 'detection': [254], 'gene': [257, 691, 728, 1003, 1145, 1163, 1263, 1293, 1353, 2351, 2735, 2769, 2813, 3321, 3921, 4452, 4469, 4477], 'expression': [258, 385, 502, 692, 1103, 1142, 1164, 1264, 1300, 1480, 1504, 1592, 2352, 2732, 2770, 3480], 'based': [260], 'on': [261, 1597], 'assay': [263, 541], 'activity.': [266], 'Because': [267, 1478, 1602, 4481], 'numerous': [268, 592, 925], 'phosphatases': [269], 'other': [270, 505, 593, 4085, 4484], 'than': [271, 506, 793, 837, 1995, 2714, 2945, 3409], 'hydrolyze': [273], 'Glc-6-P': [274, 892], '(e.g.': [275, 1255], 'alkaline': [276, 298], 'phosphatase),': [277], 'accurate': [279], 'measurement': [280], 'nonspecific': [282, 304, 366], 'Glc-6-P-phosphohydrolase': [283], 'crucial,': [285], 'especially': [286, 3399], 'intestine': [290, 1369, 3237, 4197], '(SI).': [291], 'This': [292, 408, 1249, 1632, 2146, 2509, 2615, 2723, 2937, 3150, 3475, 3511, 3591, 4002], 'tissue': [293, 389, 607, 4544], 'contains': [294, 852], 'phosphatase,': [299], 'generates': [301], 'high,': [303], 'background': [305], '(Fig.': [306, 581, 833, 928, 2345, 2628, 4000], '1A).': [307], 'Thus,': [308, 1580], 'conflicting': [309], 'reports': [310, 371, 499], 'rat': [315, 577, 702, 1179, 1684, 4315], 'SI': [316, 377, 424, 574, 1006, 1171, 1267, 1509, 1604, 1685, 1794, 1930, 2035, 2079, 2243, 2305, 2344, 2472, 2528, 2568, 2641, 2773, 2843, 2873, 3060, 3167, 3394, 3780, 3926, 4022, 4250, 4294, 4310, 4321, 4421, 4493], 'range': [317], 'from': [318, 444, 693, 893, 1168, 1792, 2041, 2150, 2170, 2600, 2605, 2871, 2961, 2964, 2972, 3031, 3176, 3514, 3595, 3657, 3748, 4160, 4198, 4354, 4419, 4467], 'nil': [319], '(5Ginsburg': [320], 'V.': [321, 1663, 1877], 'Hers': [322], 'H.G.': [323, 2309, 3102, 3122, 3180, 3200, 3527, 3572, 3600, 3723, 4047, 4097, 4126, 4204, 4224], 'Biochim.': [324, 3139, 3439, 3621, 4068], 'Biophys.': [325, 3140, 3440, 3622, 4069], 'Acta.': [326, 3141, 3441, 3623, 4070], '1960;': [327], '38:': [328, 3456, 3501, 3552], '427-434Crossref': [329], '(39)': [332, 3463, 3508, 3559], 'Scholar)': [334, 564, 1989, 3711, 3741, 4383], 'comparable': [337], 'with': [338, 1433, 1855, 2074, 2513, 2644, 2727, 3154, 3294, 3316, 3674, 4006, 4427], 'those': [339], '(6Field': [343], 'J.B.': [344, 482], 'Epstein': [345], 'S.': [346, 458, 556, 637, 742, 802, 1060, 1119, 1190, 1273, 1665, 1772, 1837, 1879, 1902, 1944, 2011, 2061, 2199, 2253, 2443, 2497, 2538, 2580, 2678, 2697, 2753, 2925, 3700, 4337, 4374, 4499, 4525], 'Egan': [347], 'T.': [348], 'Clin.': [350], 'Invest.': [351], '1965;': [352, 3815], '44:': [353], '1240-1247Crossref': [354], '(32)': [357], 'In': [360, 583, 682, 1160, 2265, 2386, 2550, 2592, 2867, 3161, 3291, 3562, 4169], 'addition': [361, 912], 'difficulties': [363], 'quantifying': [365], 'activity': [367, 374, 860, 1045, 2110, 2457, 2816, 2828, 2892, 3690, 3718, 3947], 'have': [378, 2221, 2289], 'further': [380, 1600, 2486], 'confounded': [381], 'by': [382, 393, 774, 1009, 1108, 1228, 1428, 1586, 1629, 1682, 2033, 2122, 2162, 2183, 2241, 2361, 2410, 2466, 2602, 2841, 2995, 3056, 3093, 3312, 3768, 3802, 4319], 'an': [383, 418, 940, 2392, 2656, 2978, 4242, 4296], 'anteroposterior': [384, 1359, 1501], 'gradient': [386, 688, 1502], '(see': [390, 977, 2306, 3682, 4166], 'below)': [391], 'inactivation': [395], 'during': [398, 1205, 2186, 2554, 3241, 3253, 3873, 4263, 4311], 'isolation': [400], 'intestinal': [402, 1305, 4432, 4450], 'microsomes.': [403], '2G.': [404], 'Mithieux,': [405], 'unpublished': [406], 'results.': [407], 'latter': [409, 2045, 3296, 3764], 'complication': [410], 'may': [411, 769, 936, 1257, 1295, 1795, 2039, 2113, 2177, 2234, 2941, 3672, 3742, 3979, 4148, 4251, 4439], 'be': [412, 589, 770, 1258, 1296, 1483, 1540, 1688, 1853, 2178, 2464, 2942, 2957, 3407, 3989, 4412, 4464], 'due': [413, 3477], 'presence': [416], 'inhibitor': [421], '(7Lygre': [425], 'D.G.': [426, 1331], 'Nordlie': [427, 2124], 'Biochemistry.': [429], '1968;': [430], '7:': [431], '3219-3226Crossref': [432], '(30)': [435], 'availability': [439], 'cDNA,': [442], 'isolated': [443, 609, 4196], 'mouse': [445, 4360], 'human': [447, 579, 4492], '(8Shelly': [449], 'L.L.': [450, 478], 'Lei': [451], 'K.J.': [452, 476], 'Pan': [453, 479], 'C.J.': [454, 480], 'Sakata': [455], 'S.F.': [456], 'Ruppert': [457], 'Schutz': [459], 'Chou': [461, 483], 'J.Y.': [462, 484], 'Biol.': [464, 1390, 1408, 1565, 3126, 3204, 3276, 3369, 4228, 4272], 'Chem.': [465, 1409, 1566, 3127, 3205, 3277, 3370, 4229, 4273], '1993;': [466, 486], '268:': [467], '21482-21485Abstract': [468], '9Lei': [475], 'Shelly': [477], 'Sidbury': [481], 'Science.': [485], '262:': [487], '580-583Crossref': [488], '(320)': [491], 'Scholar),': [493, 725, 1955, 2107, 3346, 3465, 4408, 4536], 'greatly': [495], 'helped': [496], 'resolve': [497], 'discordant': [498], '(10Mithieux': [511, 611, 1019], 'Vidal': [513, 613, 1021], 'H.': [514, 614, 1022, 1667, 1881], 'Zitoun': [515, 557, 615, 638, 713, 743, 803, 1023, 1061, 1089, 1120, 1274, 1750, 1767, 1815, 1832, 1897, 1939, 1977, 2006, 2056, 2095, 2194, 2248, 2438, 2492, 2533, 2577, 2673, 2694, 2748, 2854, 2903, 2920, 3695, 4033, 4500, 4522], 'C.': [516, 522, 558, 616, 622, 639, 671, 714, 744, 804, 1024, 1030, 1062, 1090, 1121, 1186, 1275, 1383, 1456, 1513, 1751, 1768, 1816, 1833, 1898, 1940, 1978, 2007, 2057, 2096, 2195, 2249, 2439, 2493, 2534, 2578, 2674, 2695, 2749, 2855, 2904, 2921, 3696, 4034, 4333, 4501, 4523], 'Bruni': [517, 553, 617, 634, 739, 799, 1025, 1057, 1116, 1187, 1270, 4334, 4496], 'N.': [518, 520, 554, 618, 620, 635, 740, 800, 1026, 1028, 1058, 1117, 1188, 1271, 3811, 4335, 4497], 'Daniele': [519, 619, 1027], 'Minassian': [521, 621, 1029, 1185, 4332], 'Diabetes.': [523, 559, 623, 676, 1031, 1195, 1670, 1775, 1840, 1884, 1905, 1947, 2014, 2064, 2202, 2256, 2446, 2500, 2541, 2583, 2681, 2700, 2756, 2928, 3338, 3703, 4342, 4528], '1996;': [524, 624, 1032, 1335, 1410, 1567], '45:': [525, 625, 1033], '891-896Crossref': [526, 626, 1034], '(129)': [529, 629, 1037], 'Using': [532], 'RT-PCR,': [533], 'Northern': [534, 775], 'blotting,': [535], 'highly': [538, 3071], 'specific': [539, 823, 2356], 'described': [542, 3159], 'Fig.': [544, 761, 3683, 4167], '1,': [545], 'we': [546], 'first': [547], 'reported': [548], '1997': [550], '(11Mithieux': [551], 'Tarpin': [555, 1189, 4336], '46': [561], '(abstr.):': [562], '76Google': [563], 'mRNA': [567, 586, 783, 1042], 'are': [570, 968, 1046, 1105, 1346, 1364, 2271, 2279, 2520, 3090, 3097, 3870, 4487], 'present': [571, 1147], 'species': [580], '1).': [582], 'contrast,': [584, 2266, 2868], 'could': [587, 1686, 4545], 'detected': [590], 'previously': [595, 1648, 2120, 4008], 'identified': [596], 'as': [597, 961, 1011, 2119, 2328, 2337, 2649, 2716, 3067], 'expressing': [598], 'it,': [599], 'including': [600], 'brain': [602], 'pancreas': [604, 1376], '(both': [605], 'whole': [606, 3078, 3396, 4458], 'islets)': [610], '12Rajas': [632], 'F.': [633, 667, 712, 738, 798, 1056, 1088, 1115, 1182, 1269, 1466, 1523, 1749, 1766, 1814, 1831, 1896, 1938, 1976, 2005, 2055, 2094, 2193, 2247, 2437, 2491, 2532, 2574, 2672, 2691, 2747, 2853, 2902, 2919, 3451, 3496, 3547, 3694, 4032, 4329, 4362, 4495, 4519], 'Montano': [636, 741, 801, 1059, 1118, 1272, 1771, 1836, 1901, 1943, 2010, 2060, 2198, 2252, 2442, 2496, 2537, 2579, 2677, 2696, 2752, 2924, 3699, 4498, 4524], 'Mithieux': [640, 672, 745, 805, 1063, 1122, 1193, 1276, 1463, 1520, 1773, 1838, 1903, 1945, 2012, 2062, 2200, 2254, 2444, 2498, 2539, 2581, 2679, 2698, 2754, 2926, 3701, 4340, 4502, 4526], 'Gastroenterology.': [642, 747, 807, 1065, 1124, 1278, 4395, 4504], '117:': [644, 749, 809, 1067, 1126, 1280, 4506], '132-139Abstract': [645, 750, 810, 1068, 1127, 1281, 4507], '(148)': [653, 758, 818, 1076, 1135, 1289, 4515], '13Portha': [656], 'B.': [657, 1400, 1557, 4368, 4392], 'Giroix': [658], 'M.H.': [659], 'Serradas': [660], 'P.': [661, 1234, 1402, 1559, 3272, 3323, 3329, 3365, 4268], 'Gangnerau': [662], 'M.N.': [663], 'Movassat': [664], 'Rajas': [666, 711, 1087, 1465, 1522, 1748, 1765, 1813, 1830, 1895, 1937, 1975, 2004, 2054, 2093, 2192, 2246, 2436, 2490, 2531, 2671, 2746, 2852, 2901, 2918, 3693, 4031], 'Bailbe': [668], 'D.': [669, 2313, 3106, 3184, 3531, 3576, 3604, 3727, 4051, 4101, 4130, 4208], 'Plachot': [670], 'Marie': [674], 'J.C.': [675], '2001;': [677, 1776, 1841, 1906, 1948, 2015, 2065, 2203, 2257, 2447, 2501, 2542, 2682, 2757, 2929, 3704, 4376], '50:': [678, 1777, 1842, 1907, 1949, 2016, 2066, 2204, 2258, 2448, 2502, 2543, 2683, 2758, 2930, 3705], '89-93Crossref': [679], 'addition,': [683, 1161], 'there': [684, 2556], 'decreasing': [687], 'duodenum': [695], 'distal': [698, 1175], 'jejunum': [699, 792], '(14Mithieux': [703, 1740, 1805, 1967, 2085, 2844, 2893, 4023], 'Bady': [705, 1081, 1459, 1516, 1742, 1807, 1969, 2087, 2846, 2895, 4025], 'I.': [706, 862, 983, 1082, 1387, 1404, 1460, 1517, 1561, 1743, 1808, 1970, 2088, 2847, 2896, 4026], 'Gautier': [707, 1083, 1744, 1809, 1971, 2089, 2848, 2897, 4027], 'A.': [708, 1084, 1454, 1458, 1511, 1515, 1661, 1745, 1810, 1875, 1972, 2090, 2849, 2898, 4028, 4375], 'Croset': [709, 1085, 1746, 1811, 1973, 2091, 2575, 2692, 2850, 2899, 4029, 4520], 'M.': [710, 864, 1086, 1385, 1747, 1764, 1812, 1829, 1894, 1936, 1974, 2003, 2053, 2092, 2191, 2245, 2435, 2489, 2530, 2576, 2670, 2693, 2745, 2851, 2900, 2917, 3138, 3274, 3327, 3367, 3438, 3453, 3498, 3549, 3620, 3692, 4030, 4067, 4270, 4521], 'Am.': [715, 1091, 1752, 1817, 1979, 2097, 2856, 2905, 3901, 4035], 'Physiol.': [717, 1093, 1239, 1334, 1754, 1819, 1981, 2099, 2858, 2907, 3220, 3849, 3903, 4037], '2004;': [718, 1094, 1755, 1820, 1982, 2100, 2859, 2908, 4038], '286:': [719, 1095, 1756, 1821, 1983, 2101, 2860, 2909, 4039], 'E370-E375Crossref': [720, 1096, 1757, 1822, 1984, 2102, 2861, 2910, 4040], '(89)': [723, 1099, 1760, 1825, 1987, 2105, 2589, 2706, 2864, 2913, 4043, 4534], 'whereas': [726, 1445, 1956, 2826], 'up': [731, 1172], 'ileum': [734, 1150, 1176], 'humans': [736], '(12Rajas': [737, 797, 1055, 1114, 1268, 4494], '1B,': [762], 'shows': [764], 'non-quantitative': [766], 'RT-PCR': [767], 'data,': [768], 'misleading.': [771], 'Quantitative': [772], 'analysis': [773, 1869], 'blot': [776], 'revealed': [777], 'amount': [780], 'about': [785, 827, 1722, 1797, 2226], '7–8': [786], 'times': [787, 4163], 'less': [788], 'abundant': [789, 3426], 'Moreover,': [821, 3685], 'activity,': [825], '1': [828, 1314], 'μmol/min/g': [829], 'mid-jejunum': [832], '1A),': [834], 'lower': [836, 1994], 'noted': [838], 'or': [842, 964, 1052, 1110, 1694, 2604, 3007, 3244, 3751], 'kidney.': [843], 'noteworthy': [846, 1140, 2025, 2349, 2805, 3083], 'translocase': [854, 884], 'required': [857, 1618], '(15Gerin': [861], 'Veiga-da-Cunha': [863], 'Achouri': [865], 'Y.': [866, 3812], 'Collet': [867], 'J.F.': [868], 'Van': [869], 'Schaftingen': [870, 980], 'E.': [871, 981, 3890], 'FEBS': [872], 'Lett.': [873], '419:': [875], '235-238Crossref': [876], '(194)': [879], 'glucose-6-phosphate': [883], 'putatively': [886], 'involved': [887, 2372, 3960, 4413], 'translocation': [890], 'cytosol': [895], 'hydrolytic': [898], 'site': [899], 'located': [902], 'at': [903, 2115, 2467, 2821, 2879, 2886, 3169], 'luminal': [905], 'side': [906], 'membrane.': [909], 'However,': [910, 4116], 'being': [914, 2046], 'also': [922, 1786, 1916, 2390, 2617, 3082, 3743, 4081, 4087, 4322, 4424], 'found': [923], 'nongluconeogenic': [926], '1B).': [929], 'suggested': [933, 2121, 2462, 4009, 4083], 'serve': [937], 'feed': [939], 'ubiquitously': [941], 'intraluminal': [943], 'hexose-6-phosphate': [944], 'dehydrogenase,': [945], 'role': [947, 1498, 2394, 2713, 3350, 3391, 4010, 4298, 4430, 4447, 4539], 'provide': [952], 'reducing': [954, 2991, 3020], 'equivalents': [955], 'needed': [956], 'several': [958], 'reductases,': [959], 'such': [960, 3066], '11β-hydroxysteroid': [962], 'dehydrogenase-1': [963], 'glutathione': [965], 'reductase,': [966], 'lumen': [972, 4422], 'Ref.': [978, 2307], '16van': [979], 'Gerin': [982], 'Biochem.': [984, 1388], '2002;': [986], '362:': [987], '513-532Crossref': [988], '(344)': [991], 'Scholar': [993, 2327], 'review).': [995], 'A': [996, 1857, 2765], 'key': [997, 2369, 3230, 3434, 4429], 'question': [998], 'whether': [1000], 'regulated': [1008], 'insulin': [1010, 1111, 2184], 'Both': [1040], 'enzymatic': [1044, 2815], 'markedly': [1047, 2047], 'induced': [1048, 2741, 2820], 'fasted': [1051, 1152, 1697, 1965, 2000, 3164, 3842, 4201], 'diabetic': [1053, 1158, 1803, 1933, 2037, 2083], 'states': [1054, 2433, 3243], '14Mithieux': [1079], 'These': [1102, 1849, 2287], 'parameters': [1104], 'rapidly': [1106, 2179], 'normalized': [1107], 're-feeding': [1109], 'treatment,': [1112], 'respectively': [1113, 1739], 'rats': [1153, 1804, 1934, 1966, 2001, 2038, 2182, 2430, 2474, 3165, 4202], 'though': [1154], 'streptozotocin-treated': [1157, 1802], 'rats.': [1159], 'strongly': [1166], 'enhanced': [1167, 1229, 3983], 'proximal': [1170, 1323, 1491], 'nursing': [1178], 'pups': [1180], '(18Chatelain': [1181, 4328], 'Pegorier': [1183, 1235, 4330], 'J.P.': [1184, 1236, 4331], 'Girard': [1191, 4338], '1998;': [1196, 1391, 4343], '47:': [1197, 4344], '882-889Crossref': [1198, 4345], '(79)': [1201, 4348], 'Nursing': [1204], 'neonatal': [1207], 'period': [1208], 'represents': [1209, 3025], 'particular': [1211], 'hypoinsulinemic': [1212, 2432, 3242], 'fed': [1213, 1693, 4326, 4436], 'state': [1214, 1698, 3843, 4327], '(because': [1215, 2295], 'relative': [1217, 3784, 4118], 'deficiency': [1218], "mother's": [1220], 'milk': [1221], 'glucidic': [1223], 'nutrients)': [1224], 'typified': [1227], '(17Girard': [1231], 'Ferre': [1233], 'Duee': [1237], 'P.H.': [1238], '72:': [1242], '507-562Crossref': [1243], '(419)': [1246], 'suggests': [1250, 2938, 4316], 'non-insulin-regulated': [1252], 'mechanisms': [1254], 'nutrition)': [1256], 'regulating': [1261], 'transcription': [1294, 1436, 3918], 'related': [1297, 1349, 1541], 'set': [1303], 'genes': [1306, 4307], 'all': [1308, 4488], 'share': [1309], 'hepatic': [1311, 2175], 'nuclear': [1312, 1347], 'factor': [1313], '(HNF1)': [1315], 'CDX': [1317], 'binding': [1318], 'sites': [1319], 'very': [1322, 1607, 3490, 3714], 'region': [1324], 'promoter': [1327, 1427], '(19Traber': [1328], 'P.G.': [1329], 'Silberg': [1330], '58:': [1336], '275-297Crossref': [1337], '(135)': [1340], 'CDX1': [1343, 1423, 1452, 1479], '-2': [1345], 'factors': [1348, 1494], '"caudal"': [1352], 'Drosophila,': [1355], 'governs': [1357], 'axis': [1360], 'development,': [1362], 'exclusively': [1365, 1555], '(CDX1': [1370], '-2)': [1372], 'endocrine': [1375], '(CDX2)': [1377], 'mammals': [1379], '(20Freund': [1380], 'J.N.': [1381, 1462, 1519], 'Domon-Dell': [1382, 1455, 1512], 'Kedinger': [1384], 'Duluc': [1386], 'Cell': [1389], '76:': [1392], '957-969Crossref': [1393], '(171)': [1396], '21Laser': [1399], 'Meda': [1401, 1558], 'Constant': [1403, 1560], 'Philippe': [1405, 1562], '271:': [1411, 1568], '28984-28994Abstract': [1412, 1569], '(57)': [1420, 1577], 'transactivates': [1424], 'forming': [1429], 'ternary': [1431], 'complex': [1432], 'machinery': [1437], 'TATA': [1440], 'box': [1441], 'gene,': [1444], 'CDX2': [1446, 1488, 1553], 'antagonizes': [1447], 'transactivating': [1449], 'effect': [1450], '(22Gautier-Stein': [1453, 1510], 'Calon': [1457, 1514], 'Freund': [1461, 1518], 'Nucleic': [1467, 1524], 'Acids': [1468, 1525], 'Res.': [1469, 1526], '2003;': [1470, 1527, 3278, 3339, 3371, 4274, 4396], '31:': [1471, 1528], '5238-5246Crossref': [1472, 1529], '(35)': [1475, 1532], 'appears': [1481], 'predominant': [1484], 'regard': [1486], 'intestine,': [1492], 'these': [1493, 1861, 3360, 4121, 4146, 4454], 'might': [1495, 1539, 3931, 4411], 'play': [1496], 'Additionally,': [1535], 'dual': [1537], 'regulation': [1538, 2634], 'absence': [1544], 'pancreatic': [1548], 'islets,': [1549], 'isotype': [1554], '(21Laser': [1556], 'extent': [1582], 'mechanism': [1585, 2480], 'nutrition-': [1589], 'hormone-sensitive': [1591], 'dependent': [1596], 'CDX1/CDX2': [1598], 'merits': [1599], 'study.': [1601], 'utilizes': [1605], 'actively,': [1608], 'assessment': [1610], 'its': [1612, 2174], 'participation': [1613], 'production': [1616, 1681, 1730, 2169, 2840, 2870, 3676, 3837], 'simultaneous': [1620], 'partitioning': [1621], 'uptake': [1626, 1927, 1962, 1997, 3862], 'tissue.': [1631, 2802, 4480], 'successfully': [1635], 'accomplished': [1636], 'using': [1637], 'combination': [1639], 'arteriovenous': [1641], 'balance': [1643], '3-[3H]glucose': [1645], 'dilution': [1646], 'techniques': [1647], 'similar': [1651, 2476], 'studies': [1652, 1862, 2212, 2353, 4355], '(23Ekberg': [1656, 1870], 'K.': [1657, 1871, 4366], 'Landau': [1658, 1872], 'B.R.': [1659, 1873], 'Wajngot': [1660, 1874], 'Chandramouli': [1662, 1876], 'Efendic': [1664, 1878], 'Brunengraber': [1666, 1880], 'Wahren': [1668, 1882], '48:': [1672, 1886], '292-298Crossref': [1673, 1887], '(198)': [1676, 1890], 'Though': [1679], 'demonstrated': [1689], 'either': [1691, 2599, 3032, 3749], 'short': [1695, 3884, 4199], 'term': [1696, 3882, 3885, 4200], '(24': [1699], 'h),': [1700], 'progressively': [1702], 'increases': [1703], 'after': [1704, 1732, 2406, 2622, 3927], '24': [1705, 2822], 'h': [1706, 1736, 2823, 2881], 'fasting,': [1708, 1738, 2825, 2883], 'where': [1709, 3247, 3643], 'accounts': [1711, 2874], '8.6': [1713], '±': [1714, 1718], '1.5': [1715], '16.9': [1717], '4.0': [1719], 'μmol/kg/min,': [1720], '20': [1723], '35%': [1725], 'total': [1727, 2238, 3304], '(EGP),': [1731], '48': [1733, 2784, 2880], '72': [1735], '24Croset': [1763, 1828, 1893, 2916], 'Hurot': [1769, 1834, 1899, 1941, 2008, 2058, 2196, 2250, 2440, 2494, 2535, 2675, 2750, 2922, 3697], 'J.M.': [1770, 1835, 1900, 1942, 2009, 2059, 2197, 2251, 2441, 2495, 2536, 2676, 2751, 2923, 3698], '740-746Crossref': [1778, 1843, 1908, 1950, 2017, 2067, 2205, 2259, 2449, 2503, 2544, 2684, 2759, 2931, 3706], '(160)': [1781, 1846, 1911, 1953, 2020, 2070, 2208, 2262, 2452, 2506, 2547, 2687, 2762, 2934, 3709], 'estimated': [1788], 'represent': [1796], 'one-third': [1798, 3313], 'EGP': [1800, 2878], 'determinations': [1850], 'must,': [1851], 'however,': [1852], 'regarded': [1854], 'caution.': [1856], 'major': [1858, 2273, 2651, 3156, 3349, 3955], 'difficulty': [1859], 'relates': [1863], 'accuracy': [1866], 'tracer': [1868], 'One': [1914, 4438], 'must': [1915, 2956], 'bear': [1917], 'mind': [1919], 'surpasses': [1924], 'only': [1931, 1959, 3098, 3311], '(24Croset': [1935, 2002, 2052, 2190, 2244, 2434, 2488, 2529, 2669, 2744, 3691], 'compensates': [1960], '72-h': [1964], 'even': [1992, 3942], 'slightly': [1993], '48-h': [1999], 'portion': [2028], 'produced': [2032, 2598, 3030], 'originate': [2040], 'glycogen': [2042, 2075], 'stores,': [2043], 'increased': [2048, 2891, 3803, 3872, 3975], 'situation': [2051], 'Consistent': [2073], 'storage': [2076], 'animals': [2084, 3361], 'glucose-phosphorylating': [2109], 'occur': [2114], 'concentration,': [2118], 'Robert': [2123], '(25Nordlie': [2125], 'Hanson': [2127], 'R.W.': [2128], 'Mehlman': [2129], 'M.A.': [2130, 3270, 3337, 3363, 4266], 'Gluconeogenesis:': [2131], 'Its': [2132], 'Regulation': [2133], 'Mammalian': [2135, 2317, 3110, 3188, 3535, 3580, 3608, 3731, 4055, 4105, 4134, 4212], 'Species.': [2136], 'John': [2137], 'Wiley': [2138], '&': [2139], 'Sons,': [2140], 'Inc.,': [2141, 2322, 3115, 3193, 3540, 3585, 3613, 3736, 4060, 4110, 4139, 4217], 'New': [2142, 2320, 2323, 3113, 3116, 3191, 3194, 3538, 3541, 3583, 3586, 3611, 3614, 3734, 3737, 4058, 4061, 4108, 4111, 4137, 4140, 4215, 4218], 'York1976:': [2143], '93-152Google': [2144], 'hypothesis': [2147, 4174], 'derived': [2148], 'mainly': [2149], 'vitro': [2152], 'experiments.': [2153], 'To': [2154], 'our': [2155], 'knowledge,': [2156], 'supported': [2161], 'definitive': [2163], 'vivo': [2165], 'experimentation.': [2166], 'Interestingly,': [2167], 'like': [2173, 3386], 'counterpart,': [2176], 'blunted': [2180], 'infusion': [2185], 'euglycemic-hyperinsulinemic': [2188], 'clamp': [2189], 'Incorporation': [2211], '14C-': [2214], '13C-labeled': [2216], 'gluconeogenic': [2217, 2274, 2359, 2652, 2986, 3305, 3435, 3936, 4306, 4485], 'precursors': [2218, 2360], 'indicated': [2222], 'glutamine': [2224, 2621, 2648, 2715, 2962, 3006, 3053, 3089, 3422, 3472, 3494, 3568, 3658, 3864, 3878, 4183], '(for': [2225, 2230], '80%)': [2227], 'glycerol': [2229, 2331, 2737, 2965, 3055], 'residual': [2232], '20%)': [2233], 'account': [2235, 3036], 'synthesized': [2240], 'alanine,': [2269, 2975], 'substrates': [2275, 2606, 3937], 'liver,': [2278, 2388, 2594], 'incorporated': [2281, 2522], 'SI.': [2286, 2363, 2722, 2954], 'findings': [2288], 'implicated': [2290], 'glutaminase,': [2291], 'aminotransferase': [2293], '(ALT)': [2294], 'glutamate': [2296, 2625, 3668], 'dehydrogenase': [2297, 2335, 2414, 2997, 3003, 3009, 3717], 'quantitative': [2301], 'importance': [2302, 4119], '26Windmueller': [2308, 4046], 'Haüssinger': [2310, 3103, 3181, 3528, 3573, 3601, 3724, 4048, 4098, 4127, 4205], 'H.D.': [2311, 3104, 3182, 3529, 3574, 3602, 3725, 4049, 4099, 4128, 4206], 'Sies': [2312, 3105, 3183, 3530, 3575, 3603, 3726, 4050, 4100, 4129, 4207], 'Glutamine': [2314, 3107, 3185, 3532, 3577, 3605, 3728, 4052, 4102, 4131, 4209], 'Metabolism': [2315, 3108, 3186, 3533, 3578, 3606, 3729, 4053, 4103, 4132, 4210], 'Tissues.': [2318, 3111, 3189, 3536, 3581, 3609, 3732, 4056, 4106, 4135, 4213], 'Springer-Verlag': [2319, 3112, 3190, 3537, 3582, 3610, 3733, 4057, 4107, 4136, 4214], 'York': [2321, 3114, 3192, 3539, 3584, 3612, 3735, 4059, 4109, 4138, 4216], 'York1984:': [2324, 3117, 3195, 3542, 3587, 3615, 3738, 4062, 4112, 4141, 4219], '61-77Crossref': [2325, 3118, 3196, 3543, 3588, 3616, 3739, 4063, 4113, 4142, 4220], 'review)),': [2330], 'kinase,': [2332, 3995], 'glycerol-3-phosphate': [2334, 3008], '(G3PDH)': [2336], 'critical': [2338], 'enzymes': [2339, 2889, 4086, 4486], '2).': [2346, 2629, 3684], 'support': [2354, 3826, 4171], 'selection': [2357], 'Pyruvate': [2364], 'carboxylase': [2365], '(PC)': [2366], 'anaplerotic': [2370], 'removal': [2375], 'citric': [2378, 3965], 'acid': [2379, 3429, 3966], 'cycle': [2380, 2611, 3967], 'intermediates': [2381], 'glyceroneogenesis': [2383], 'lipogenesis.': [2385], 'plays': [2391, 4295], 'important': [2393, 4297, 4442], 'gluconeogenesis,': [2396, 3398], 'accounting': [2397], 'incorporation': [2400], 'conversion': [2407, 2623], 'ALT': [2411, 3598, 3757], '(LDH),': [2415], 'respectively,': [2416, 3753], 'glucose.': [2418, 3648], 'Accordingly,': [2419], 'Vmax': [2421], 'PC': [2423, 2459, 2603, 2636, 3689], 'doubled': [2425], 'Conversely,': [2455], 'decreased': [2465, 3310], 'least': [2468, 3170], '80%': [2469], 'under': [2475, 3245], 'conditions,': [2477], 'although': [2478, 3085, 3421], 'suppression': [2483], 'would': [2484, 3385], 'merit': [2485], 'characterization': [2487], 'keeping': [2512, 4426], 'fact': [2515, 2729, 3770], 'formed': [2525], 'contrast': [2551], 'hypoinsulinemia': [2555, 2743], 'strong': [2559, 3292, 4170, 4303], 'induction': [2560, 2809, 3654, 3916, 3944, 4304], 'carboxykinase': [2564], '(PEPCK-C)': [2565], '(27Rajas': [2573], '2000;': [2584, 2701, 4529], '49:': [2585, 2702, 4530], '1165-1168Crossref': [2586, 2703, 4531], 'PEPCK-C': [2595, 2638, 2794, 2812, 2946, 3308, 3353, 3923, 3952, 3978, 4012], 'uses': [2596], 'oxaloacetate,': [2597], 'cycling': [2607], 'through': [2608, 3307, 3756, 3762], 'Krebs': [2610], 'generate': [2613], 'phosphoenolpyruvate.': [2614], 'fate': [2619], 'α-ketoglutarate': [2627, 2996], 'Therefore,': [2630], 'coordinate': [2632], 'inverse': [2633], 'fits': [2642], 'well': [2643], 'use': [2646], 'substrate': [2653], 'explanation': [2657], 'lack': [2660], 'utilization': [2662, 3051], '27Rajas': [2690, 4518], 'Glycerol': [2709], 'lesser': [2712], 'precursor': [2719, 3436], 'agreement': [2726, 3293, 4005], 'kinase': [2738], 'recent': [2766, 3267, 4352], 'study': [2767], 'early': [2776], 'phases': [2777], 'fasting': [2779, 3068, 3886, 4165, 4264], '(i.e.': [2780], 'between': [2781, 3667, 4189], '0': [2782], 'h)': [2785], 'highlighted': [2787], 'respective': [2789], 'roles': [2790, 3231], 'initiation': [2797, 2949], 'rapid': [2808, 3915], '(its': [2814], 'already': [2818], 'maximally': [2819], 'yet': [2831], 'increased)': [2832], 'sufficient': [2835], 'trigger': [2837], 'detectable': [2838], '20%': [2876], 'time': [2885], 'exhibit': [2890], 'more': [2943, 3408], 'emphasized': [2958, 3301], 'that,': [2969, 3084], 'unlike': [2970], 'exergonic': [2979], 'process.': [2980], 'pathways': [2987, 4122], 'involve': [2988], 'reactions': [2989], 'generating': [2990], 'equivalents,': [2992, 3021], 'e.g.': [2993, 3252, 4262, 4466], 'catalyzed': [2994], '(NADH': [2998, 3010], '+': [2999, 3011], 'H+)': [3000, 3012], 'succinate': [3002], '(FADH2)': [3004], 'glycerol.': [3014], 'Assuming': [3015], 'aerobic': [3017], 'oxidation': [3018, 3831], 'net': [3023], 'yield': [3024], '4': [3026], 'ATP': [3027, 3038], 'per': [3028], 'precursor,': [3033], 'taking': [3034], 'requirement': [3039, 3175], 'urea': [3042], 'synthesis': [3043, 3594, 3984, 3999], 'case': [3046], 'glutamine.': [3048], 'increasing': [3050, 3754, 3997], 'periods': [3062], 'energy': [3064, 3174], 'depletion': [3065], 'thus': [3070, 3971], 'favorable': [3072], 'energetics': [3075], 'body.': [3079], 'actively': [3091, 3565], 'utilized': [3092], 'they': [3096], 'partially': [3099], 'oxidized': [3100], '(26Windmueller': [3101, 3179, 3526, 3571, 3599, 3722, 4096, 4125, 4203], '28Windmueller': [3121, 3199, 4223], 'Spaeth': [3123, 3201, 4225], 'A.E.': [3124, 3202, 4226], '1978;': [3128, 3206, 3222, 3851, 4230], '253:': [3129, 3207, 4231], '69-76Abstract': [3130, 3208, 4232], '29Watford': [3137, 3619, 4066], '1994;': [3142, 3442, 3624, 4071], '1200:': [3143, 3443, 3625, 4072], '73-78Crossref': [3144, 3444, 3626, 4073], '(45)': [3147, 3226, 3447, 3629, 3855, 4076], 'line': [3153], 'their': [3155], 'metabolic': [3157], 'fates': [3158], 'below.': [3160], 'fact,': [3162, 3563], 'derives': [3168], '50%': [3171], 'ketone': [3177], 'bodies': [3178], '30Hanson': [3215], 'P.J.': [3216, 3845], 'Parsons': [3217, 3846], 'D.S.': [3218, 3847], '(Lond.).': [3221, 3850], '278:': [3223, 3279, 3372, 3852, 4275], '55-67Crossref': [3224, 3853], 'and/or': [3235, 3758, 4195, 4248, 4472], 'supply': [3240, 3358, 3934, 4156], 'conditions': [3246], 'absent,': [3251], 'anhepatic': [3255], 'phase': [3256], 'transplantation': [3259], 'humans,': [3261], 'discussed': [3264], 'review': [3268], '(31Magnuson': [3269, 3362, 4265], 'She': [3271, 3364, 4267], 'Shiota': [3273, 3326, 3366, 4269], '32485-32488Abstract': [3280, 3373, 4276], '(27)': [3288, 3381, 4284], 'concept,': [3297], 'flux': [3306, 3755, 3761, 3976], 'mice': [3315, 4471, 4473], 'liver-specific': [3317], 'knock-out': [3318, 4359, 4470], '(32She': [3322], 'Burgess': [3324], 'S.C.': [3325], 'Flakoll': [3328], 'Donahue': [3330], 'E.P.': [3331], 'Malloy': [3332], 'C.R.': [3333], 'Sherry': [3334], 'A.D.': [3335], 'Magnuson': [3336], '52:': [3340], '1649-1654Crossref': [3341], '(90)': [3344], 'suggesting': [3347], 'extrahepatic': [3352], 'systemic': [3356], 'We': [3384, 4287], 'stress': [3388], 'body': [3397, 4459], 'splanchnic': [3402], 'bed,': [3403], 'likely': [3405, 3651], 'just': [3410], 'contributor.': [3415], 'indeed': [3418], 'striking': [3419], 'most': [3425], 'plasma': [3427], 'amino': [3428], 'considered': [3432], '(29Watford': [3437], '33Hartmann': [3450, 3546], 'Plauth': [3452, 3497, 3548], 'Metabolism.': [3454, 3499, 3550], '1989;': [3455, 3500, 3551], '18-24Abstract': [3457, 3502, 3553], 'unable': [3469], 'utilize': [3471, 3566], 'gluconeogenesis.': [3474], 'hepatocytes': [3482], 'liver-type': [3485], 'glutaminase': [3486, 3525], 'low': [3491, 3715], 'affinity': [3492], '(33Hartmann': [3495], 'strikingly': [3512], 'differs': [3513], 'enterocytes,': [3515], 'affinity,': [3523], 'kidney-type': [3524], 'enterocytes': [3564, 3839, 4194], 'favors': [3592, 3789], 'via': [3597, 3639, 3977, 3993], 'Alanine,': [3632], 'turn,': [3634], 'continues': [3635], 'portal': [3641], 'vein': [3642], 'converted': [3646, 3990], 'ALT-dependent': [3665], 'coupling': [3666], 'utilization,': [3671], 'synergize': [3673], 'reduction': [3687], 'enterocyte': [3721], 'divert': [3744], 'pool': [3747, 4019], 'oxidation,': [3752], 'LDH.': [3759], 'facilitated': [3767], 'kinetics': [3773], 'LDH': [3775, 3796], 'isoforms': [3776], '(rich': [3781], 'M': [3783, 3798], 'L': [3786], 'polypeptide': [3787], 'chains)': [3788], 'conversion,': [3794], 'type': [3797], 'inhibited': [3801], 'concentrations': [3805], '(34Fondy': [3806], 'T.P.': [3807], 'Kaplan': [3808], 'N.O.': [3809], 'Ann.': [3810], 'Acad.': [3813, 4371], 'Sci.': [3814, 4372], '119:': [3816], '888-904Crossref': [3817], '(43)': [3820], 'following': [3824], 'observations': [3825], 'proposal.': [3828], '1)': [3829], 'virtually': [3833], 'abolished,': [3834], 'favoring': [3835], '(30Hanson': [3844], 'Scholar);': [3857], '2)': [3859], 'concomitantly': [3871], 'processing': [3875], 'load': [3879], 'versus': [3883], 'dogs': [3888], '(35Cersosimo': [3889], 'Williams': [3891], 'P.E.': [3892], 'Radosevich': [3893], 'P.M.': [3894], 'Hoxworth': [3895], 'B.T.': [3896], 'Lacy': [3897], 'W.W.': [3898], 'Abumrad': [3899], 'N.N.': [3900], '1986;': [3904], '250:': [3905], 'E622-E628PubMed': [3906], 'worth': [3911], 'emphasizing': [3912], '24-h': [3929], 'fast': [3930], 'enhance': [3932], 'furnished': [3938], 'without': [3943], 'production.': [3951], 'cataplerotic': [3956], 'disposal': [3963], 'intermediates.': [3968], 'expected': [3972], 'result': [3980], 'phosphoenolpyruvate,': [3986], 'can': [3988], 'thereby': [3996], '3).': [4001, 4168], 'replenishment': [4015], 'synthesize': [4088], 'pyruvate,': [4089], 'malic': [4091], 'oxaloacetate': [4094], 'decarboxylase': [4095], 'remains': [4123], 'uncertain': [4124], 'Altogether,': [4145], 'processes': [4147], 'function': [4149], 'increase': [4151], 'earliest': [4162], 'observation': [4177], 'substantial': [4180], 'proportion': [4181], 'carbons': [4184], 'almost': [4186], 'equally': [4187], 'distributed': [4188], 'becoming': [4241], 'accepted': [4243], 'view': [4244], 'augment': [4252], 'controlling': [4256], 'homeostasis': [4258, 4555], 'various': [4260], 'situations,': [4261], 'emphasize': [4288], 'here': [4289], 'balance.': [4301], 'suckling': [4312], 'occurs': [4323], 'suggestion,': [4353], 'Glut2': [4358], '(36Stumpel': [4361], 'Burcelin': [4363], 'R.': [4364, 4388], 'Jungermann': [4365], 'Thorens': [4367], 'Proc.': [4369], 'Natl.': [4370], 'U.': [4373], '98:': [4377], '11330-11335Crossref': [4378], '(125)': [4381], 'Glc-6-Pase-deficient': [4385], 'patients': [4386], '(37Santer': [4387], 'Hillebrand': [4389], 'Steinmann': [4391], 'Schaub': [4393], '124:': [4397], '34-39Abstract': [4398], '(54)': [4406], 'absorption': [4416], 'state.': [4437], 'anticipate': [4440], 'new': [4443], 'insights': [4444], 'different': [4455], 'aspects': [4456], 'metabolism': [4461], 'will': [4462], 'soon': [4463], 'available,': [4465], 'intestine-specific': [4468], 'overexpress': [4475], 'deciphering': [4537], 'constitute': [4546], 'significant': [4548], 'breakthrough': [4549], 'understanding': [4552], 'humans.': [4557]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2036616293', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 8}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 9}, {'year': 2013, 'cited_by_count': 9}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-14T15:42:04.419981', 'created_date': '2016-06-24'}