Title: Histometry of normal thyroid glands in neonatal and adult rats
Abstract: Abstract The present histometric study is on thyroid glands of Wistar rats ranging in age from 0 to 120 days. The mean volume of one lobe of the thyroid in 4‐month‐old animals was some 22‐, 10‐, 5‐, and 3‐fold greater, respectively, than the volumes in the newborn, 5‐, 10‐, and 30‐day‐old rats. At 4 months of age the mean length of the lobe was 3 times greater than at birth. The volumetric fractions (Vv) of the different histological components (follicular cells, C‐cells, colloid, and interstitial tissue) changed considerably in the course of development. The Vv of follicular cells diminished from 61.4% at birth to 37.2% at 4 months. C‐cells increased from 2.9% in the newborn to 4% at 15 days, with no further significant change at 4 months. Colloid and stroma together represented 35.7% at birth, increasing to 58.5% at 120 days. In the course of the first 4 months of life, the absolute volumes occupied by follicular cells, C‐cells, colloid, and stroma increased 13.25, 30.75, 38.6, and 33.7 times, respectively; these changes reflect the variations that occur in the volume of the gland and the Vv throughout postnatal development.
Publication Year: 1991
Publication Date: 1991-08-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 22
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