Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2036228214', 'doi': 'https://doi.org/10.1007/s11033-011-0928-6', 'title': 'Cell growth arrest and apoptosis induced by Oct4 or Nanog knockdown in mouse embryonic stem cells: a possible role of Trp53', 'display_name': 'Cell growth arrest and apoptosis induced by Oct4 or Nanog knockdown in mouse embryonic stem cells: a possible role of Trp53', 'publication_year': 2011, 'publication_date': '2011-06-25', 'ids': {'openalex': 'https://openalex.org/W2036228214', 'doi': 'https://doi.org/10.1007/s11033-011-0928-6', 'mag': '2036228214', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21706347'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s11033-011-0928-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S197962172', 'display_name': 'Molecular Biology Reports', 'issn_l': '0301-4851', 'issn': ['0301-4851', '1573-4978'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5084543201', 'display_name': 'Tianji Chen', 'orcid': 'https://orcid.org/0000-0002-3026-2066'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Tianji Chen', 'raw_affiliation_strings': ['central south university'], 'affiliations': [{'raw_affiliation_string': 'central south university', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045364810', 'display_name': 'Juan Du', 'orcid': 'https://orcid.org/0000-0001-8190-3524'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Juan Du', 'raw_affiliation_strings': ['central south university'], 'affiliations': [{'raw_affiliation_string': 'central south university', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5101396789', 'display_name': 'Guangxiu Lu', 'orcid': 'https://orcid.org/0009-0002-4732-6756'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Guangxiu Lu', 'raw_affiliation_strings': ['central south university'], 'affiliations': [{'raw_affiliation_string': 'central south university', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.773, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 33, 'citation_normalized_percentile': {'value': 0.758279, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '39', 'issue': '2', 'first_page': '1855', 'last_page': '1861'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10505', 'display_name': 'Induction and Differentiation of Pluripotent Stem Cells', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10505', 'display_name': 'Induction and Differentiation of Pluripotent Stem Cells', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10878', 'display_name': 'Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12140', 'display_name': 'Molecular Mechanisms of Kidney Development and Disease', 'score': 0.9911, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/homeobox-protein-nanog', 'display_name': 'Homeobox protein NANOG', 'score': 0.9870182}, {'id': 'https://openalex.org/keywords/rex1', 'display_name': 'Rex1', 'score': 0.799713}, {'id': 'https://openalex.org/keywords/nanog-homeobox-protein', 'display_name': 'Nanog Homeobox Protein', 'score': 0.5731995}, {'id': 'https://openalex.org/keywords/embryonic-stem-cells', 'display_name': 'Embryonic Stem Cells', 'score': 0.471921}], 'concepts': [{'id': 'https://openalex.org/C207701140', 'wikidata': 'https://www.wikidata.org/wiki/Q420522', 'display_name': 'Homeobox protein NANOG', 'level': 5, 'score': 0.9870182}, {'id': 'https://openalex.org/C173396325', 'wikidata': 'https://www.wikidata.org/wiki/Q1501275', 'display_name': 'Gene knockdown', 'level': 3, 'score': 0.92982256}, {'id': 'https://openalex.org/C145103041', 'wikidata': 'https://www.wikidata.org/wiki/Q1151519', 'display_name': 'Embryonic stem cell', 'level': 3, 'score': 0.8015106}, {'id': 'https://openalex.org/C207168726', 'wikidata': 'https://www.wikidata.org/wiki/Q18050439', 'display_name': 'Rex1', 'level': 5, 'score': 0.799713}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5962353}, {'id': 'https://openalex.org/C2908926650', 'wikidata': 'https://www.wikidata.org/wiki/Q420522', 'display_name': 'Nanog Homeobox Protein', 'level': 5, 'score': 0.5731995}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.5360553}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5070081}, {'id': 'https://openalex.org/C127561419', 'wikidata': 'https://www.wikidata.org/wiki/Q224527', 'display_name': 'Downregulation and upregulation', 'level': 3, 'score': 0.50036335}, {'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.45998353}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.39412695}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3594228}, {'id': 'https://openalex.org/C107459253', 'wikidata': 'https://www.wikidata.org/wiki/Q674925', 'display_name': 'Induced pluripotent stem cell', 'level': 4, 'score': 0.20632923}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.19454709}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.13457596}], 'mesh': [{'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D053595', 'descriptor_name': 'Embryonic Stem Cells', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D018398', 'descriptor_name': 'Homeodomain Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D050814', 'descriptor_name': 'Octamer Transcription Factor-3', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D016159', 'descriptor_name': 'Tumor Suppressor Protein p53', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001973', 'descriptor_name': 'Bromodeoxyuridine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017931', 'descriptor_name': 'DNA Primers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017931', 'descriptor_name': 'DNA Primers', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D053595', 'descriptor_name': 'Embryonic Stem Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005434', 'descriptor_name': 'Flow Cytometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055785', 'descriptor_name': 'Gene Knockdown Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018398', 'descriptor_name': 'Homeodomain Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000071317', 'descriptor_name': 'Nanog Homeobox Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050814', 'descriptor_name': 'Octamer Transcription Factor-3', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034622', 'descriptor_name': 'RNA Interference', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060888', 'descriptor_name': 'Real-Time Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020133', 'descriptor_name': 'Reverse Transcriptase Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016159', 'descriptor_name': 'Tumor Suppressor Protein p53', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s11033-011-0928-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S197962172', 'display_name': 'Molecular Biology Reports', 'issn_l': '0301-4851', 'issn': ['0301-4851', '1573-4978'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21706347', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 25, 'referenced_works': ['https://openalex.org/W1966636083', 'https://openalex.org/W1968728409', 'https://openalex.org/W1970515701', 'https://openalex.org/W1981088384', 'https://openalex.org/W1982331566', 'https://openalex.org/W1985263934', 'https://openalex.org/W2022489847', 'https://openalex.org/W2038249969', 'https://openalex.org/W2051875932', 'https://openalex.org/W2059006768', 'https://openalex.org/W2061004792', 'https://openalex.org/W2069408483', 'https://openalex.org/W2072747624', 'https://openalex.org/W2077956417', 'https://openalex.org/W2081690888', 'https://openalex.org/W2096753123', 'https://openalex.org/W2105361655', 'https://openalex.org/W2106840146', 'https://openalex.org/W2126851387', 'https://openalex.org/W2128323764', 'https://openalex.org/W2144284013', 'https://openalex.org/W2150163104', 'https://openalex.org/W2162262059', 'https://openalex.org/W2325068802', 'https://openalex.org/W2411145099'], 'related_works': ['https://openalex.org/W4254787690', 'https://openalex.org/W3196835192', 'https://openalex.org/W2624131434', 'https://openalex.org/W2373796651', 'https://openalex.org/W2148099781', 'https://openalex.org/W2123806948', 'https://openalex.org/W2063334316', 'https://openalex.org/W2036228214', 'https://openalex.org/W1976337831', 'https://openalex.org/W1975823499'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2036228214', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 7}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-09-24T14:08:08.760026', 'created_date': '2016-06-24'}