Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2035971824', 'doi': 'https://doi.org/10.1016/0006-291x(88)90240-9', 'title': 'Reconstituted U1 small nuclear ribonucleoprotein complex restores 5′ splice site cleavage activity', 'display_name': 'Reconstituted U1 small nuclear ribonucleoprotein complex restores 5′ splice site cleavage activity', 'publication_year': 1988, 'publication_date': '1988-08-01', 'ids': {'openalex': 'https://openalex.org/W2035971824', 'doi': 'https://doi.org/10.1016/0006-291x(88)90240-9', 'mag': '2035971824', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2970258'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0006-291x(88)90240-9', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S151589183', 'display_name': 'Biochemical and Biophysical Research Communications', 'issn_l': '0006-291X', 'issn': ['0006-291X', '1090-2104'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5050629314', 'display_name': 'Clay B. Siegall', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I193531525', 'display_name': 'George Washington University', 'ror': 'https://ror.org/00y4zzh67', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I193531525']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Clay B. Siegall', 'raw_affiliation_strings': ['The George Washington University, Department of Genetics, 2300 I Street, N.W., Washington D.C. 20037 USA'], 'affiliations': [{'raw_affiliation_string': 'The George Washington University, Department of Genetics, 2300 I Street, N.W., Washington D.C. 20037 USA', 'institution_ids': ['https://openalex.org/I193531525']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006724562', 'display_name': 'Timothy Hla', 'orcid': 'https://orcid.org/0000-0001-8355-4065'}, 'institutions': [{'id': 'https://openalex.org/I193531525', 'display_name': 'George Washington University', 'ror': 'https://ror.org/00y4zzh67', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I193531525']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Timothy T. Hla', 'raw_affiliation_strings': ['The George Washington University, Department of Biochemistry, 2300 I Street, N.W., Washington D.C. 20037 USA'], 'affiliations': [{'raw_affiliation_string': 'The George Washington University, Department of Biochemistry, 2300 I Street, N.W., Washington D.C. 20037 USA', 'institution_ids': ['https://openalex.org/I193531525']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5058116407', 'display_name': 'Ajit Kumar', 'orcid': 'https://orcid.org/0000-0002-3979-881X'}, 'institutions': [{'id': 'https://openalex.org/I193531525', 'display_name': 'George Washington University', 'ror': 'https://ror.org/00y4zzh67', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I193531525']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ajit Kumar', 'raw_affiliation_strings': ['The George Washington University, Department of Biochemistry, 2300 I Street, N.W., Washington D.C. 20037 USA', 'The George Washington University, Department of Genetics, 2300 I Street, N.W., Washington D.C. 20037 USA'], 'affiliations': [{'raw_affiliation_string': 'The George Washington University, Department of Biochemistry, 2300 I Street, N.W., Washington D.C. 20037 USA', 'institution_ids': ['https://openalex.org/I193531525']}, {'raw_affiliation_string': 'The George Washington University, Department of Genetics, 2300 I Street, N.W., Washington D.C. 20037 USA', 'institution_ids': ['https://openalex.org/I193531525']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2770, 'currency': 'USD', 'value_usd': 2770, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.235901, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 53, 'max': 61}, 'biblio': {'volume': '154', 'issue': '3', 'first_page': '1010', 'last_page': '1017'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10604', 'display_name': 'RNA Research and Splicing', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10604', 'display_name': 'RNA Research and Splicing', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10521', 'display_name': 'RNA and protein synthesis mechanisms', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11482', 'display_name': 'RNA modifications and cancer', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/snrnp', 'display_name': 'snRNP', 'score': 0.972412}, {'id': 'https://openalex.org/keywords/small-nuclear-ribonucleoprotein', 'display_name': 'Small nuclear ribonucleoprotein', 'score': 0.8040699}, {'id': 'https://openalex.org/keywords/precursor-mrna', 'display_name': 'Precursor mRNA', 'score': 0.7218554}, {'id': 'https://openalex.org/keywords/cleavage', 'display_name': 'Cleavage (geology)', 'score': 0.6402575}, {'id': 'https://openalex.org/keywords/small-nuclear-rna', 'display_name': 'Small nuclear RNA', 'score': 0.6275657}, {'id': 'https://openalex.org/keywords/prp24', 'display_name': 'Prp24', 'score': 0.5486992}, {'id': 'https://openalex.org/keywords/heterogeneous-nuclear-ribonucleoprotein', 'display_name': 'Heterogeneous nuclear ribonucleoprotein', 'score': 0.4102239}], 'concepts': [{'id': 'https://openalex.org/C68483431', 'wikidata': 'https://www.wikidata.org/wiki/Q2076770', 'display_name': 'snRNP', 'level': 5, 'score': 0.972412}, {'id': 'https://openalex.org/C54458228', 'wikidata': 'https://www.wikidata.org/wiki/Q237218', 'display_name': 'RNA splicing', 'level': 4, 'score': 0.8128104}, {'id': 'https://openalex.org/C2908584439', 'wikidata': 'https://www.wikidata.org/wiki/Q2076770', 'display_name': 'Small nuclear ribonucleoprotein', 'level': 5, 'score': 0.8040699}, {'id': 'https://openalex.org/C75934600', 'wikidata': 'https://www.wikidata.org/wiki/Q419245', 'display_name': 'Ribonucleoprotein', 'level': 4, 'score': 0.73044366}, {'id': 'https://openalex.org/C102063271', 'wikidata': 'https://www.wikidata.org/wiki/Q7243183', 'display_name': 'Precursor mRNA', 'level': 5, 'score': 0.7218554}, {'id': 'https://openalex.org/C175156509', 'wikidata': 'https://www.wikidata.org/wiki/Q1990218', 'display_name': 'Cleavage (geology)', 'level': 3, 'score': 0.6402575}, {'id': 'https://openalex.org/C100299639', 'wikidata': 'https://www.wikidata.org/wiki/Q284578', 'display_name': 'Small nuclear RNA', 'level': 5, 'score': 0.6275657}, {'id': 'https://openalex.org/C52990999', 'wikidata': 'https://www.wikidata.org/wiki/Q7252931', 'display_name': 'Prp24', 'level': 5, 'score': 0.5486992}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5470248}, {'id': 'https://openalex.org/C2780114586', 'wikidata': 'https://www.wikidata.org/wiki/Q40260', 'display_name': 'Cell nucleus', 'level': 3, 'score': 0.45455894}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.44263673}, {'id': 'https://openalex.org/C2909472194', 'wikidata': 'https://www.wikidata.org/wiki/Q417662', 'display_name': 'Heterogeneous nuclear ribonucleoprotein', 'level': 5, 'score': 0.4102239}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.36775157}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.29188007}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.25906873}, {'id': 'https://openalex.org/C2780723820', 'wikidata': 'https://www.wikidata.org/wiki/Q1934178', 'display_name': 'Nucleus', 'level': 2, 'score': 0.18349949}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.15212706}, {'id': 'https://openalex.org/C41258723', 'wikidata': 'https://www.wikidata.org/wiki/Q2919111', 'display_name': 'RNA-dependent RNA polymerase', 'level': 4, 'score': 0.09475446}, {'id': 'https://openalex.org/C151730666', 'wikidata': 'https://www.wikidata.org/wiki/Q7205', 'display_name': 'Paleontology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C43369102', 'wikidata': 'https://www.wikidata.org/wiki/Q2307625', 'display_name': 'Fracture (geology)', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D005914', 'descriptor_name': 'Globins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D012326', 'descriptor_name': 'RNA Splicing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012261', 'descriptor_name': 'Ribonucleoproteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005796', 'descriptor_name': 'Genes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005914', 'descriptor_name': 'Globins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006367', 'descriptor_name': 'HeLa Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006367', 'descriptor_name': 'HeLa Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012322', 'descriptor_name': 'RNA Precursors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012322', 'descriptor_name': 'RNA Precursors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012342', 'descriptor_name': 'RNA, Small Nuclear', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012342', 'descriptor_name': 'RNA, Small Nuclear', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012261', 'descriptor_name': 'Ribonucleoproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017411', 'descriptor_name': 'Ribonucleoproteins, Small Nuclear', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013698', 'descriptor_name': 'Templates, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014158', 'descriptor_name': 'Transcription, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0006-291x(88)90240-9', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S151589183', 'display_name': 'Biochemical and Biophysical Research Communications', 'issn_l': '0006-291X', 'issn': ['0006-291X', '1090-2104'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2970258', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.41, 'display_name': 'Clean water and sanitation', 'id': 'https://metadata.un.org/sdg/6'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 20, 'referenced_works': ['https://openalex.org/W1530522395', 'https://openalex.org/W1968223204', 'https://openalex.org/W1968322556', 'https://openalex.org/W1971314065', 'https://openalex.org/W1977542860', 'https://openalex.org/W1982610079', 'https://openalex.org/W1989313376', 'https://openalex.org/W1993243592', 'https://openalex.org/W1995478437', 'https://openalex.org/W2009103135', 'https://openalex.org/W2021054898', 'https://openalex.org/W2024588724', 'https://openalex.org/W2025975378', 'https://openalex.org/W2052745709', 'https://openalex.org/W2073105366', 'https://openalex.org/W2073602088', 'https://openalex.org/W2078119356', 'https://openalex.org/W2090041541', 'https://openalex.org/W2122071753', 'https://openalex.org/W2173963963'], 'related_works': ['https://openalex.org/W4212899779', 'https://openalex.org/W2751654510', 'https://openalex.org/W2396471642', 'https://openalex.org/W2153375374', 'https://openalex.org/W2098415098', 'https://openalex.org/W2035971824', 'https://openalex.org/W2028353886', 'https://openalex.org/W2010696389', 'https://openalex.org/W1974630548', 'https://openalex.org/W1968223204'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2035971824', 'counts_by_year': [{'year': 2020, 'cited_by_count': 1}], 'updated_date': '2024-12-15T23:53:04.969784', 'created_date': '2016-06-24'}