Title: Protein Conformation-Induced Modulation of Ligand Binding Kinetics: A Femtosecond Mid-IR Study of Nitric Oxide Binding Trajectories in Myoglobin
Abstract: By directly probing the photolyzed NO from MbNO at physiological conditions, the rebinding trajectories of the photoproduct were obtained, from which we found that a time-dependent barrier arising from protein relaxation on the same time scale as that of the rebinding process is responsible for the NO nonexponential rebinding.
Publication Year: 2005
Publication Date: 2005-06-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 32
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