Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2034098009', 'doi': 'https://doi.org/10.3109/01677063.2014.885966', 'title': 'Defective Motile Cilia in<i>Prickle2</i>-Deficient Mice', 'display_name': 'Defective Motile Cilia in<i>Prickle2</i>-Deficient Mice', 'publication_year': 2014, 'publication_date': '2014-04-07', 'ids': {'openalex': 'https://openalex.org/W2034098009', 'doi': 'https://doi.org/10.3109/01677063.2014.885966', 'mag': '2034098009', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24708399'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.3109/01677063.2014.885966', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S64145856', 'display_name': 'Journal of Neurogenetics', 'issn_l': '0167-7063', 'issn': ['0167-7063', '1026-8057', '1563-5260'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5029039226', 'display_name': 'Levi P. Sowers', 'orcid': 'https://orcid.org/0000-0002-5375-9825'}, 'institutions': [{'id': 'https://openalex.org/I126307644', 'display_name': 'University of Iowa', 'ror': 'https://ror.org/036jqmy94', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I126307644']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Levi P. Sowers', 'raw_affiliation_strings': ['Department of Neurology, The University of Iowa,\nIowa City, Iowa, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, The University of Iowa,\nIowa City, Iowa, USA', 'institution_ids': ['https://openalex.org/I126307644']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055109681', 'display_name': 'Terry C. Yin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I126307644', 'display_name': 'University of Iowa', 'ror': 'https://ror.org/036jqmy94', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I126307644']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Terry Yin', 'raw_affiliation_strings': ['Department of Psychiatry, The University of Iowa,\nIowa City, Iowa, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Psychiatry, The University of Iowa,\nIowa City, Iowa, USA', 'institution_ids': ['https://openalex.org/I126307644']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001466650', 'display_name': 'Vinit B. Mahajan', 'orcid': 'https://orcid.org/0000-0003-1886-1741'}, 'institutions': [{'id': 'https://openalex.org/I126307644', 'display_name': 'University of Iowa', 'ror': 'https://ror.org/036jqmy94', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I126307644']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Vinit B. Mahajan', 'raw_affiliation_strings': ['Department of Opthalmology, The University of Iowa,\nIowa City, Iowa, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Opthalmology, The University of Iowa,\nIowa City, Iowa, USA', 'institution_ids': ['https://openalex.org/I126307644']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5033502887', 'display_name': 'Alexander G. Bassuk', 'orcid': 'https://orcid.org/0000-0002-4067-2157'}, 'institutions': [{'id': 'https://openalex.org/I126307644', 'display_name': 'University of Iowa', 'ror': 'https://ror.org/036jqmy94', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I126307644']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Alexander G. Bassuk', 'raw_affiliation_strings': ['Department of Neurology, The University of Iowa,\nIowa City, Iowa, USA', 'Department of Pediatrics, The University of Iowa,\nIowa City, Iowa, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurology, The University of Iowa,\nIowa City, Iowa, USA', 'institution_ids': ['https://openalex.org/I126307644']}, {'raw_affiliation_string': 'Department of Pediatrics, The University of Iowa,\nIowa City, Iowa, USA', 'institution_ids': ['https://openalex.org/I126307644']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5033502887'], 'corresponding_institution_ids': ['https://openalex.org/I126307644'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.787, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 10, 'citation_normalized_percentile': {'value': 0.734598, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '28', 'issue': '1-2', 'first_page': '146', 'last_page': '152'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11412', 'display_name': 'Genetic and Kidney Cyst Diseases', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11412', 'display_name': 'Genetic and Kidney Cyst Diseases', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10492', 'display_name': 'Microtubule and mitosis dynamics', 'score': 0.9891, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11928', 'display_name': 'Genetic Syndromes and Imprinting', 'score': 0.9852, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/motile-cilium', 'display_name': 'Motile cilium', 'score': 0.9594522}, {'id': 'https://openalex.org/keywords/ependyma', 'display_name': 'Ependyma', 'score': 0.6948602}, {'id': 'https://openalex.org/keywords/intraflagellar-transport', 'display_name': 'Intraflagellar Transport', 'score': 0.43409768}, {'id': 'https://openalex.org/keywords/ciliopathy', 'display_name': 'Ciliopathy', 'score': 0.42072812}], 'concepts': [{'id': 'https://openalex.org/C100094513', 'wikidata': 'https://www.wikidata.org/wiki/Q180436', 'display_name': 'Cilium', 'level': 2, 'score': 0.97399294}, {'id': 'https://openalex.org/C2910722709', 'wikidata': 'https://www.wikidata.org/wiki/Q180436', 'display_name': 'Motile cilium', 'level': 3, 'score': 0.9594522}, {'id': 'https://openalex.org/C58207958', 'wikidata': 'https://www.wikidata.org/wiki/Q33596', 'display_name': 'Motility', 'level': 2, 'score': 0.7892661}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7330407}, {'id': 'https://openalex.org/C2776663378', 'wikidata': 'https://www.wikidata.org/wiki/Q1134467', 'display_name': 'Ependyma', 'level': 3, 'score': 0.6948602}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6230721}, {'id': 'https://openalex.org/C37590093', 'wikidata': 'https://www.wikidata.org/wiki/Q978456', 'display_name': 'Intraflagellar transport', 'level': 4, 'score': 0.43409768}, {'id': 'https://openalex.org/C2780561973', 'wikidata': 'https://www.wikidata.org/wiki/Q203031', 'display_name': 'Ciliopathy', 'level': 4, 'score': 0.42072812}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.3617608}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.34199446}, {'id': 'https://openalex.org/C115811362', 'wikidata': 'https://www.wikidata.org/wiki/Q189998', 'display_name': 'Flagellum', 'level': 3, 'score': 0.31548387}, {'id': 'https://openalex.org/C127716648', 'wikidata': 'https://www.wikidata.org/wiki/Q104053', 'display_name': 'Phenotype', 'level': 3, 'score': 0.2695139}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.15964684}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.13668475}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.09312096}], 'mesh': [{'descriptor_ui': 'D002923', 'descriptor_name': 'Cilia', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D002923', 'descriptor_name': 'Cilia', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D006849', 'descriptor_name': 'Hydrocephalus', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D006849', 'descriptor_name': 'Hydrocephalus', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D060588', 'descriptor_name': 'LIM Domain Proteins', 'qualifier_ui': 'Q000172', 'qualifier_name': 'deficiency', 'is_major_topic': True}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000172', 'qualifier_name': 'deficiency', 'is_major_topic': True}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016764', 'descriptor_name': 'Cell Polarity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016764', 'descriptor_name': 'Cell Polarity', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002552', 'descriptor_name': 'Cerebral Ventricles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002552', 'descriptor_name': 'Cerebral Ventricles', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D002552', 'descriptor_name': 'Cerebral Ventricles', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D002923', 'descriptor_name': 'Cilia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002923', 'descriptor_name': 'Cilia', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D004805', 'descriptor_name': 'Ependyma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004805', 'descriptor_name': 'Ependyma', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D004805', 'descriptor_name': 'Ependyma', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D006849', 'descriptor_name': 'Hydrocephalus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060588', 'descriptor_name': 'LIM Domain Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060588', 'descriptor_name': 'LIM Domain Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008279', 'descriptor_name': 'Magnetic Resonance Imaging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008822', 'descriptor_name': 'Mice, Transgenic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046529', 'descriptor_name': 'Microscopy, Electron, Transmission', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.3109/01677063.2014.885966', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S64145856', 'display_name': 'Journal of Neurogenetics', 'issn_l': '0167-7063', 'issn': ['0167-7063', '1026-8057', '1563-5260'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24708399', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 26, 'referenced_works': ['https://openalex.org/W1562392324', 'https://openalex.org/W1966088670', 'https://openalex.org/W1971002207', 'https://openalex.org/W1988987349', 'https://openalex.org/W1999476407', 'https://openalex.org/W2002027085', 'https://openalex.org/W2016959238', 'https://openalex.org/W2022840073', 'https://openalex.org/W2029823974', 'https://openalex.org/W2033965339', 'https://openalex.org/W2037850388', 'https://openalex.org/W2048102969', 'https://openalex.org/W2048790780', 'https://openalex.org/W2055555061', 'https://openalex.org/W2068732761', 'https://openalex.org/W2094055557', 'https://openalex.org/W2106803950', 'https://openalex.org/W2113619522', 'https://openalex.org/W2136854118', 'https://openalex.org/W2142546000', 'https://openalex.org/W2152990036', 'https://openalex.org/W2159869422', 'https://openalex.org/W2163035368', 'https://openalex.org/W2166404638', 'https://openalex.org/W2416788485', 'https://openalex.org/W4320577290'], 'related_works': ['https://openalex.org/W4385684609', 'https://openalex.org/W4383821461', 'https://openalex.org/W4380683307', 'https://openalex.org/W4322154584', 'https://openalex.org/W4237217929', 'https://openalex.org/W2471599151', 'https://openalex.org/W2415033250', 'https://openalex.org/W2167377309', 'https://openalex.org/W2030939638', 'https://openalex.org/W1519697983'], 'abstract_inverted_index': {'Motile': [0], 'cilia': [1, 14, 83, 92, 109], 'play': [2], 'diverse': [3], 'roles': [4], 'across': [5], 'phyla': [6], 'and': [7, 10, 46, 78, 111], 'cell': [8, 36], 'types,': [9], 'abnormalities': [11, 25], 'in': [12, 26, 43, 58, 80], 'motile': [13, 23, 49, 65, 82, 91, 108], 'lead': [15], 'to': [16, 61], 'numerous': [17], 'disease': [18], 'states,': [19], 'including': [20, 39], 'hydrocephalus.': [21], 'Although': [22], 'ciliary': [24], 'Prickle2': [27, 102], 'mutants': [28], 'have': [29], 'not': [30, 70], 'yet': [31], 'been': [32], 'described,': [33], 'the': [34, 44, 81, 85], 'planar': [35], 'polarity': [37], 'genes,': [38], 'Prickle2,': [40], 'are': [41], 'implicated': [42], 'development': [45, 110], 'function': [47], 'of': [48, 84, 89], 'cilia.': [50, 66], 'This': [51], 'report': [52], 'evaluates': [53], 'Prickle2-deficient': [54, 67], 'mice': [55, 68], 'for': [56, 105], 'dysfunction': [57], 'processes': [59], 'known': [60], 'depend': [62], 'on': [63], 'functioning': [64], 'do': [69, 74], 'develop': [71], 'hydrocephalus,': [72], 'but': [73], 'display': [75], 'abnormal': [76], 'morphology': [77, 88], 'motility': [79], 'ependyma.': [86], 'The': [87], 'tracheal': [90], 'is': [93, 103], 'also': [94], 'abnormal.': [95], 'Taken': [96], 'together,': [97], 'these': [98], 'results': [99], 'demonstrate': [100], 'that': [101], 'required': [104], 'normal': [106], 'ependymal': [107], 'function.': [112]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2034098009', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 3}], 'updated_date': '2024-12-24T15:15:00.746560', 'created_date': '2016-06-24'}