Publication Information

{'id': 'https://openalex.org/W2034014394', 'doi': 'https://doi.org/10.1159/000238056', 'title': 'Bactericidal Activity of Cefazolin, Cefoxitin, and Cefmetazole against <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i>', 'display_name': 'Bactericidal Activity of Cefazolin, Cefoxitin, and Cefmetazole against <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i>', 'publication_year': 1982, 'publication_date': '1982-01-01', 'ids': {'openalex': 'https://openalex.org/W2034014394', 'doi': 'https://doi.org/10.1159/000238056', 'mag': '2034014394', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7035088'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1159/000238056', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S92531173', 'display_name': 'Chemotherapy', 'issn_l': '0009-3157', 'issn': ['0009-3157', '1421-9794'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317820', 'host_organization_name': 'Karger Publishers', 'host_organization_lineage': ['https://openalex.org/P4310317820'], 'host_organization_lineage_names': ['Karger Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5102283756', 'display_name': 'Sachiko Gotô', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I129634264', 'display_name': 'Toho University', 'ror': 'https://ror.org/02hcx7n63', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I129634264']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Sachiko Goto', 'raw_affiliation_strings': ['Department of Microbiology, Toho University School of Medicine, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, Toho University School of Medicine, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I129634264']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083782157', 'display_name': 'Hiroshi Sakamoto', 'orcid': 'https://orcid.org/0000-0002-8767-2111'}, 'institutions': [{'id': 'https://openalex.org/I129634264', 'display_name': 'Toho University', 'ror': 'https://ror.org/02hcx7n63', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I129634264']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiroshi Sakamoto', 'raw_affiliation_strings': ['Department of Microbiology, Toho University School of Medicine, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, Toho University School of Medicine, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I129634264']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048993740', 'display_name': 'Masaru Ogawa', 'orcid': 'https://orcid.org/0000-0001-6030-3554'}, 'institutions': [{'id': 'https://openalex.org/I129634264', 'display_name': 'Toho University', 'ror': 'https://ror.org/02hcx7n63', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I129634264']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Masatoshi Ogawa', 'raw_affiliation_strings': ['Department of Microbiology, Toho University School of Medicine, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, Toho University School of Medicine, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I129634264']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023149224', 'display_name': 'Akiyoshi Tsuji', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I129634264', 'display_name': 'Toho University', 'ror': 'https://ror.org/02hcx7n63', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I129634264']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Akiyoshi Tsuji', 'raw_affiliation_strings': ['Department of Microbiology, Toho University School of Medicine, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, Toho University School of Medicine, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I129634264']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5044397980', 'display_name': 'Shôgo Kuwahara', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I129634264', 'display_name': 'Toho University', 'ror': 'https://ror.org/02hcx7n63', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I129634264']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shogo Kuwahara', 'raw_affiliation_strings': ['Department of Microbiology, Toho University School of Medicine, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, Toho University School of Medicine, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I129634264']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.225, 'has_fulltext': False, 'cited_by_count': 11, 'citation_normalized_percentile': {'value': 0.611111, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 80, 'max': 81}, 'biblio': {'volume': '28', 'issue': '1', 'first_page': '18', 'last_page': '25'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10147', 'display_name': 'Global Challenge of Antibiotic Resistance in Bacteria', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1313', 'display_name': 'Molecular Medicine'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10147', 'display_name': 'Global Challenge of Antibiotic Resistance in Bacteria', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1313', 'display_name': 'Molecular Medicine'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11036', 'display_name': 'Pharmacokinetics of Antibiotics in Critically Ill Patients', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13454', 'display_name': 'Biological Activities of Phenothiazines and Related Compounds', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cefmetazole', 'display_name': 'Cefmetazole', 'score': 0.9767777}, {'id': 'https://openalex.org/keywords/cefazolin', 'display_name': 'Cefazolin', 'score': 0.94830316}, {'id': 'https://openalex.org/keywords/cefalotin', 'display_name': 'Cefalotin', 'score': 0.49473426}, {'id': 'https://openalex.org/keywords/antimicrobial', 'display_name': 'Antimicrobial', 'score': 0.459125}], 'concepts': [{'id': 'https://openalex.org/C2776237055', 'wikidata': 'https://www.wikidata.org/wiki/Q5057238', 'display_name': 'Cefmetazole', 'level': 4, 'score': 0.9767777}, {'id': 'https://openalex.org/C2776124114', 'wikidata': 'https://www.wikidata.org/wiki/Q2353907', 'display_name': 'Cefoxitin', 'level': 4, 'score': 0.9563435}, {'id': 'https://openalex.org/C2778353156', 'wikidata': 'https://www.wikidata.org/wiki/Q415739', 'display_name': 'Cefazolin', 'level': 3, 'score': 0.94830316}, {'id': 'https://openalex.org/C2777058267', 'wikidata': 'https://www.wikidata.org/wiki/Q132592', 'display_name': 'Klebsiella pneumoniae', 'level': 4, 'score': 0.7896452}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.7271445}, {'id': 'https://openalex.org/C64778159', 'wikidata': 'https://www.wikidata.org/wiki/Q271021', 'display_name': 'Cephalosporin', 'level': 3, 'score': 0.5726525}, {'id': 'https://openalex.org/C2779233340', 'wikidata': 'https://www.wikidata.org/wiki/Q2736126', 'display_name': 'Cefalotin', 'level': 4, 'score': 0.49473426}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.45613697}, {'id': 'https://openalex.org/C547475151', 'wikidata': 'https://www.wikidata.org/wiki/Q25419', 'display_name': 'Escherichia coli', 'level': 3, 'score': 0.41517138}, {'id': 'https://openalex.org/C501593827', 'wikidata': 'https://www.wikidata.org/wiki/Q12187', 'display_name': 'Antibiotics', 'level': 2, 'score': 0.360526}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.2474072}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.243868}, {'id': 'https://openalex.org/C2779489039', 'wikidata': 'https://www.wikidata.org/wiki/Q188121', 'display_name': 'Staphylococcus aureus', 'level': 3, 'score': 0.16859424}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.05252692}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002511', 'descriptor_name': 'Cephalosporins', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D007711', 'descriptor_name': 'Klebsiella pneumoniae', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D002437', 'descriptor_name': 'Cefazolin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D002437', 'descriptor_name': 'Cefazolin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015311', 'descriptor_name': 'Cefmetazole', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002440', 'descriptor_name': 'Cefoxitin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D002440', 'descriptor_name': 'Cefoxitin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002511', 'descriptor_name': 'Cephalosporins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002513', 'descriptor_name': 'Cephamycins', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D002513', 'descriptor_name': 'Cephamycins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007711', 'descriptor_name': 'Klebsiella pneumoniae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008826', 'descriptor_name': 'Microbial Sensitivity Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1159/000238056', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S92531173', 'display_name': 'Chemotherapy', 'issn_l': '0009-3157', 'issn': ['0009-3157', '1421-9794'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317820', 'host_organization_name': 'Karger Publishers', 'host_organization_lineage': ['https://openalex.org/P4310317820'], 'host_organization_lineage_names': ['Karger Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7035088', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W615981323', 'https://openalex.org/W2487169079', 'https://openalex.org/W2420792604', 'https://openalex.org/W2392724075', 'https://openalex.org/W2392606755', 'https://openalex.org/W2166132024', 'https://openalex.org/W2101503243', 'https://openalex.org/W2034014394', 'https://openalex.org/W2016573306', 'https://openalex.org/W1963778845'], 'abstract_inverted_index': {'The': [0, 19, 42, 97], 'bactericidal': [1, 95, 113], 'activity': [2, 44, 114], 'of': [3, 11, 29, 50, 63, 75, 90, 108, 120], 'cefazolin,': [4], 'cefoxitin,': [5], 'and': [6, 14, 40, 47, 52, 58, 103, 115], 'cefmetazole': [7, 53], 'against': [8, 25], 'clinical': [9], 'isolates': [10], 'Escherichia': [12], 'coli': [13], 'Klebsiella': [15], 'pneumoniae': [16], 'was': [17, 54, 59, 87], 'investigated.': [18], 'mean': [20], 'geometric': [21], 'minimum': [22], 'inhibition': [23, 118], 'concentrations': [24, 107], '200': [26], 'strains': [27], 'each': [28], 'the': [30, 56, 66, 72, 76, 88, 91, 101, 111, 116], 'test': [31], 'organisms': [32], 'were': [33], 'lowest': [34], 'for': [35], 'cefmetazole,': [36], 'followed': [37], 'by': [38], 'cefazolin': [39, 51, 86, 109], 'cefoxitin.': [41, 64], 'killing': [43], 'at': [45], '5': [46], '50': [48], 'microgram/ml': [49], 'almost': [55], 'same': [57], 'superior': [60], 'to': [61], 'that': [62, 100], 'In': [65], 'kinetic': [67], 'model': [68], 'under': [69], 'conditions': [70], 'simulating': [71], 'serum': [73, 106], 'levels': [74], 'two': [77], 'drugs': [78, 93], 'in': [79, 94], 'humans': [80], 'after': [81], 'intravenous': [82], 'injection': [83], '(1': [84], 'g),': [85], 'strongest': [89], 'three': [92], 'activity.': [96], 'results': [98], 'indicate': [99], 'highest': [102], 'most': [104], 'prolonged': [105], 'reflected': [110], 'strong': [112], 'longest': [117], 'period': [119], 'bacterial': [121], 'regrowth.': [122]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2034014394', 'counts_by_year': [{'year': 2022, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-09-25T23:52:32.043388', 'created_date': '2016-06-24'}