Publication Information

{'id': 'https://openalex.org/W2033644025', 'doi': 'https://doi.org/10.1111/j.1463-1326.2009.01126.x', 'title': 'Effects of intensive insulin therapy alone and with added pioglitazone on renal salt/water balance and fluid compartment shifts in type 2 diabetes', 'display_name': 'Effects of intensive insulin therapy alone and with added pioglitazone on renal salt/water balance and fluid compartment shifts in type 2 diabetes', 'publication_year': 2009, 'publication_date': '2009-11-02', 'ids': {'openalex': 'https://openalex.org/W2033644025', 'doi': 'https://doi.org/10.1111/j.1463-1326.2009.01126.x', 'mag': '2033644025', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19889003'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1463-1326.2009.01126.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S148394532', 'display_name': 'Diabetes Obesity and Metabolism', 'issn_l': '1462-8902', 'issn': ['1462-8902', '1463-1326'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5089649262', 'display_name': 'Sunder Mudaliar', 'orcid': 'https://orcid.org/0000-0003-4441-8508'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}, {'id': 'https://openalex.org/I4210099595', 'display_name': 'VA San Diego Healthcare System', 'ror': 'https://ror.org/00znqwq11', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210099595', 'https://openalex.org/I4210138663']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'S. Mudaliar', 'raw_affiliation_strings': ['Department of Medicine, University of California San Diego, CA, USA', 'VA San Diego Healthcare System, San Diego, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of California San Diego, CA, USA', 'institution_ids': ['https://openalex.org/I36258959']}, {'raw_affiliation_string': 'VA San Diego Healthcare System, San Diego, CA, USA', 'institution_ids': ['https://openalex.org/I4210099595']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110733568', 'display_name': 'Anna Chang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}, {'id': 'https://openalex.org/I4210099595', 'display_name': 'VA San Diego Healthcare System', 'ror': 'https://ror.org/00znqwq11', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210099595', 'https://openalex.org/I4210138663']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'A. R. Chang', 'raw_affiliation_strings': ['Department of Medicine, University of California San Diego, CA, USA', 'VA San Diego Healthcare System, San Diego, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of California San Diego, CA, USA', 'institution_ids': ['https://openalex.org/I36258959']}, {'raw_affiliation_string': 'VA San Diego Healthcare System, San Diego, CA, USA', 'institution_ids': ['https://openalex.org/I4210099595']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005405894', 'display_name': 'Vanita R. Aroda', 'orcid': 'https://orcid.org/0000-0002-7706-4585'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}, {'id': 'https://openalex.org/I4210099595', 'display_name': 'VA San Diego Healthcare System', 'ror': 'https://ror.org/00znqwq11', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210099595', 'https://openalex.org/I4210138663']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'V. R. Aroda', 'raw_affiliation_strings': ['Department of Medicine, University of California San Diego, CA, USA', 'VA San Diego Healthcare System, San Diego, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of California San Diego, CA, USA', 'institution_ids': ['https://openalex.org/I36258959']}, {'raw_affiliation_string': 'VA San Diego Healthcare System, San Diego, CA, USA', 'institution_ids': ['https://openalex.org/I4210099595']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076400392', 'display_name': 'Edward C. Chao', 'orcid': 'https://orcid.org/0000-0002-8871-3309'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}, {'id': 'https://openalex.org/I4210099595', 'display_name': 'VA San Diego Healthcare System', 'ror': 'https://ror.org/00znqwq11', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210099595', 'https://openalex.org/I4210138663']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'E. Chao', 'raw_affiliation_strings': ['Department of Medicine, University of California San Diego, CA, USA', 'VA San Diego Healthcare System, San Diego, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of California San Diego, CA, USA', 'institution_ids': ['https://openalex.org/I36258959']}, {'raw_affiliation_string': 'VA San Diego Healthcare System, San Diego, CA, USA', 'institution_ids': ['https://openalex.org/I4210099595']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108752882', 'display_name': 'P. Burke', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210099595', 'display_name': 'VA San Diego Healthcare System', 'ror': 'https://ror.org/00znqwq11', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210099595', 'https://openalex.org/I4210138663']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'P. Burke', 'raw_affiliation_strings': ['VA San Diego Healthcare System; San Diego CA USA'], 'affiliations': [{'raw_affiliation_string': 'VA San Diego Healthcare System; San Diego CA USA', 'institution_ids': ['https://openalex.org/I4210099595']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073950544', 'display_name': 'Sunita Baxi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}, {'id': 'https://openalex.org/I4210099595', 'display_name': 'VA San Diego Healthcare System', 'ror': 'https://ror.org/00znqwq11', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210099595', 'https://openalex.org/I4210138663']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'S. Baxi', 'raw_affiliation_strings': ['Department of Medicine, University of California San Diego, CA, USA', 'VA San Diego Healthcare System, San Diego, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of California San Diego, CA, USA', 'institution_ids': ['https://openalex.org/I36258959']}, {'raw_affiliation_string': 'VA San Diego Healthcare System, San Diego, CA, USA', 'institution_ids': ['https://openalex.org/I4210099595']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056008800', 'display_name': 'Kathryn Griver', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210099595', 'display_name': 'VA San Diego Healthcare System', 'ror': 'https://ror.org/00znqwq11', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210099595', 'https://openalex.org/I4210138663']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'K. A. Griver', 'raw_affiliation_strings': ['VA San Diego Healthcare System; San Diego CA USA'], 'affiliations': [{'raw_affiliation_string': 'VA San Diego Healthcare System; San Diego CA USA', 'institution_ids': ['https://openalex.org/I4210099595']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103420852', 'display_name': 'Daniel T. O’Connor', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'D. T. O’Connor', 'raw_affiliation_strings': ['Department of Medicine, University of California-San Diego, CA, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of California-San Diego, CA, USA.', 'institution_ids': ['https://openalex.org/I36258959']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5045462483', 'display_name': 'Robert R. Henry', 'orcid': 'https://orcid.org/0000-0002-4821-0117'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}, {'id': 'https://openalex.org/I4210099595', 'display_name': 'VA San Diego Healthcare System', 'ror': 'https://ror.org/00znqwq11', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210099595', 'https://openalex.org/I4210138663']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'R. R. Henry', 'raw_affiliation_strings': ['Department of Medicine, University of California San Diego, CA, USA', 'VA San Diego Healthcare System, San Diego, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of California San Diego, CA, USA', 'institution_ids': ['https://openalex.org/I36258959']}, {'raw_affiliation_string': 'VA San Diego Healthcare System, San Diego, CA, USA', 'institution_ids': ['https://openalex.org/I4210099595']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4940, 'currency': 'USD', 'value_usd': 4940, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.285, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 22, 'citation_normalized_percentile': {'value': 0.837998, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': '12', 'issue': '2', 'first_page': '133', 'last_page': '138'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11967', 'display_name': 'Electrolyte and hormonal disorders', 'score': 0.9976, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11967', 'display_name': 'Electrolyte and hormonal disorders', 'score': 0.9976, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12279', 'display_name': 'Body Composition Measurement Techniques', 'score': 0.9967, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12267', 'display_name': 'Diet and metabolism studies', 'score': 0.9939, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pioglitazone', 'display_name': 'Pioglitazone', 'score': 0.9589132}], 'concepts': [{'id': 'https://openalex.org/C2778384471', 'wikidata': 'https://www.wikidata.org/wiki/Q417765', 'display_name': 'Pioglitazone', 'level': 4, 'score': 0.9589132}, {'id': 'https://openalex.org/C2113261', 'wikidata': 'https://www.wikidata.org/wiki/Q2914458', 'display_name': 'Extracellular fluid', 'level': 3, 'score': 0.8095227}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.75019014}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.7388958}, {'id': 'https://openalex.org/C2779306644', 'wikidata': 'https://www.wikidata.org/wiki/Q2002370', 'display_name': 'Insulin', 'level': 2, 'score': 0.6982077}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.51595837}, {'id': 'https://openalex.org/C2777180221', 'wikidata': 'https://www.wikidata.org/wiki/Q3025883', 'display_name': 'Type 2 diabetes', 'level': 3, 'score': 0.51418567}, {'id': 'https://openalex.org/C555293320', 'wikidata': 'https://www.wikidata.org/wiki/Q12206', 'display_name': 'Diabetes mellitus', 'level': 2, 'score': 0.43129435}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.38162097}, {'id': 'https://openalex.org/C28406088', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Extracellular', 'level': 2, 'score': 0.19356567}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0656172}], 'mesh': [{'descriptor_ui': 'D001834', 'descriptor_name': 'Body Water', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D003924', 'descriptor_name': 'Diabetes Mellitus, Type 2', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D007004', 'descriptor_name': 'Hypoglycemic Agents', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D007328', 'descriptor_name': 'Insulin', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D009765', 'descriptor_name': 'Obesity', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D045162', 'descriptor_name': 'Thiazolidinediones', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D001786', 'descriptor_name': 'Blood Glucose', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001786', 'descriptor_name': 'Blood Glucose', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001823', 'descriptor_name': 'Body Composition', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D001823', 'descriptor_name': 'Body Composition', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001834', 'descriptor_name': 'Body Water', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D001834', 'descriptor_name': 'Body Water', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003924', 'descriptor_name': 'Diabetes Mellitus, Type 2', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D003924', 'descriptor_name': 'Diabetes Mellitus, Type 2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018495', 'descriptor_name': 'Fluid Shifts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007004', 'descriptor_name': 'Hypoglycemic Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D007004', 'descriptor_name': 'Hypoglycemic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007328', 'descriptor_name': 'Insulin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D007328', 'descriptor_name': 'Insulin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009765', 'descriptor_name': 'Obesity', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D009765', 'descriptor_name': 'Obesity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077205', 'descriptor_name': 'Pioglitazone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045162', 'descriptor_name': 'Thiazolidinediones', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D045162', 'descriptor_name': 'Thiazolidinediones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014882', 'descriptor_name': 'Water-Electrolyte Balance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014882', 'descriptor_name': 'Water-Electrolyte Balance', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D014882', 'descriptor_name': 'Water-Electrolyte Balance', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1463-1326.2009.01126.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S148394532', 'display_name': 'Diabetes Obesity and Metabolism', 'issn_l': '1462-8902', 'issn': ['1462-8902', '1463-1326'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19889003', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Clean water and sanitation', 'score': 0.84, 'id': 'https://metadata.un.org/sdg/6'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 26, 'referenced_works': ['https://openalex.org/W1966195317', 'https://openalex.org/W1983310674', 'https://openalex.org/W1987692887', 'https://openalex.org/W2004170935', 'https://openalex.org/W2004693666', 'https://openalex.org/W2021459014', 'https://openalex.org/W2036663374', 'https://openalex.org/W2044034911', 'https://openalex.org/W2044848016', 'https://openalex.org/W2046218459', 'https://openalex.org/W2049227087', 'https://openalex.org/W2060060473', 'https://openalex.org/W2062560800', 'https://openalex.org/W2066409356', 'https://openalex.org/W2082432305', 'https://openalex.org/W2108550834', 'https://openalex.org/W2138385978', 'https://openalex.org/W2148403865', 'https://openalex.org/W2157738006', 'https://openalex.org/W2166653277', 'https://openalex.org/W2166796262', 'https://openalex.org/W2168294324', 'https://openalex.org/W2169563394', 'https://openalex.org/W2171851249', 'https://openalex.org/W2415382680', 'https://openalex.org/W4240449862'], 'related_works': ['https://openalex.org/W46097970', 'https://openalex.org/W3142910047', 'https://openalex.org/W2965513749', 'https://openalex.org/W2752583015', 'https://openalex.org/W2556250268', 'https://openalex.org/W2341560996', 'https://openalex.org/W2324414017', 'https://openalex.org/W2057743727', 'https://openalex.org/W1967713685', 'https://openalex.org/W1897237112'], 'abstract_inverted_index': {'To': [0], 'evaluate': [1], 'the': [2, 93, 198, 233, 247, 279, 286], 'effects': [3], 'of': [4, 27, 82, 89, 95, 193, 249, 282], 'intensive': [5], 'insulin': [6, 90, 118, 144, 180, 218, 273], 'therapy': [7, 91, 274], 'alone': [8, 119, 145, 181, 219], 'or': [9, 45], 'with': [10, 32, 75, 117, 125, 143, 154, 168, 179, 203, 217, 269, 272, 289], 'added': [11, 126, 155, 169, 204], 'pioglitazone': [12, 39, 96, 127, 156, 170, 205, 250], 'on': [13], 'renal': [14], 'salt/water': [15], 'balance': [16], 'and': [17, 50, 67, 85, 92, 102, 104, 109, 122, 133, 149, 166, 266], 'body': [18, 64, 106, 260], 'fluid': [19, 69, 163], 'compartment': [20], 'shifts': [21], 'in': [22, 232, 259, 293], 'type': [23, 33, 239], '2': [24, 34, 240], 'diabetes.A': [25], 'total': [26, 63], '25': [28], 'insulin-treated,': [29], 'obese': [30, 238], 'patients': [31], 'diabetes': [35], 'were': [36, 228], 'randomized': [37], 'to': [38, 56, 197, 209, 223], '45': [40], 'mg': [41], '(n': [42, 47], '=': [43, 48, 131, 147, 187], '12)': [44], 'placebo': [46], '13)': [49], 'treated': [51], 'intensively': [52, 236], 'for': [53], '12-16': [54], 'weeks': [55], 'achieve': [57], 'equivalent': [58, 244], 'glycaemic': [59, 245], 'control.': [60], 'We': [61], 'measured': [62], 'water': [65, 261], '(TBW)': [66], 'extracellular/intracellular': [68], 'by': [70, 79], 'bioimpedance': [71], 'analysis;': [72], 'plasma/RBC': [73], 'volume': [74, 137], 'I(131)albumin;': [76], 'sodium': [77, 195, 283], 'handling': [78], 'fractional': [80], 'excretion': [81], 'sodium/lithium': [83], '(FeNa/FeLi)': [84], 'other': [86, 234], 'renal/hormonal': [87], 'parameters.Intensification': [88], 'addition': [94, 248], 'significantly': [97, 165, 202], 'improved': [98], 'glycaemia': [99], '(HbA1C': [100], '7.8-7.2%': [101], '7.6-7.1%)': [103], 'increased': [105, 114, 138, 164, 201], 'weight': [107, 253], '(1.7': [108], '4.9': [110], 'kg)': [111], 'respectively.': [112], 'TBW': [113], '1.7': [115], 'l': [116, 124, 142, 153], '(65%': [120], 'intracellular)': [121], '1.6': [123], '(75%': [128], 'extracellular)': [129], '(p': [130, 146, 157], '0.06': [132], '0.09': [134], 'respectively).': [135], 'Plasma': [136], '0.2': [139, 173, 184], '+/-': [140, 151, 172, 183, 207, 211, 221, 225], '0.1': [141, 152], '0.05)': [148], '0.4': [150], '<': [158, 176], '0.05).': [159], 'Extravascular,': [160], 'extracellular': [161, 265], '(interstitial)': [162], 'more': [167], '(0.8': [171], 'l,': [174, 185], 'p': [175, 186], '0.01)': [177], 'than': [178], '(0.4': [182], 'ns).': [188], 'At': [189], 'steady-state,': [190], 'FeLi': [191], '(marker': [192], 'proximal-tubular': [194], 'delivery': [196], 'distal': [199, 287], 'nephron)': [200], '(12.4': [206], '1.3': [208], '18.0': [210], '3.2%)': [212], 'vs.': [213], 'no': [214, 229, 290], 'significant': [215, 230], 'change': [216, 292], '(15.4': [220], '1.2': [222], '14.5': [224], '2.3%).': [226], 'There': [227], 'changes': [231], 'parameters.In': [235], 'insulin-treated': [237], 'diabetic': [241], 'patients,': [242], 'at': [243, 285], 'control,': [246], 'causes': [251], 'greater': [252], 'gain,': [254], 'but': [255], 'a': [256], 'similar': [257], 'increase': [258, 271], 'that': [262], 'is': [263], 'mainly': [264], 'interstitial': [267], 'compared': [268], 'intracellular': [270], 'alone.': [275], 'Pioglitazone': [276], 'also': [277], 'increases': [278], 'filtered': [280], 'load': [281], 'reabsorbed': [284], 'nephron': [288], 'net': [291], 'FeNa.': [294]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2033644025', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2025-01-12T01:08:34.930565', 'created_date': '2016-06-24'}