Title: A possible link between multiple sclerosis and Creutzfeldt–Jakob disease based on clinical, genetic, pathological and immunological evidence involving Acinetobacter bacteria
Abstract: Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the nervous system. There is an increasingly likelihood that MS could be triggered/perpetuated by environmental (microbial) agents. Sporadic Creutzfeldt-Jakob disease (sCJD) is a relatively rare but fatal disease, which shows various clinical, genetic, pathological and immunological features through which it resembles a severe form of MS. The disease in some patients with MS may show a rapidly downhill course with death occurring within one to two years and a similar situation occurs in sCJD. The occurrence of these comparative similarities between MS and sCJD could be explained on the basis that both of these conditions might be sharing a common aetiopathogenic factor such as infection by Acinetobacter microbes and this possibility could be investigated further by carrying out immunological studies on a relatively large numbers of patients with MS and CJD.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 11
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