Title: Coinfection and the evolution of parasite virulence
Abstract: Restricted accessMoreSectionsView PDF ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InRedditEmail Cite this article May Robert M. and Nowak Martin A. 1995Coinfection and the evolution of parasite virulenceProc. R. Soc. Lond. B.261209–215http://doi.org/10.1098/rspb.1995.0138SectionRestricted accessArticleCoinfection and the evolution of parasite virulence Robert M. May Google Scholar Find this author on PubMed Search for more papers by this author and Martin A. Nowak Google Scholar Find this author on PubMed Search for more papers by this author Robert M. May Google Scholar Find this author on PubMed and Martin A. Nowak Google Scholar Find this author on PubMed Published:22 August 1995https://doi.org/10.1098/rspb.1995.0138AbstractAnalyses of the selection pressures acting on parasite virulence are made more complicated when individual hosts can simultaneously harbour many different strains or genotypes of a parasite. Here we explore the evolutionary dynamics of host-parasite associations in which individual hosts can be coinfected with many different parasite strains. (We take coinfection to mean that each strain transmits at a rate unaffected by the presence of others in the same host.) This study thus represents the opposite extreme to our earlier work on superinfection in which there is a dominance hierarchy such that only the most virulent strain present in a host is transmitted. For highly diverse populations of parasite strains, we find that such coinfection leads to selection for strains whose virulence-levels lie in a relatively narrow band close to the maximum consistent with the parasite's basic preproductive ratio, R0, exceeding unity.FootnotesThis text was harvested from a scanned image of the original document using optical character recognition (OCR) software. As such, it may contain errors. Please contact the Royal Society if you find an error you would like to see corrected. 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Publication Year: 1995
Publication Date: 1995-08-22
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 748
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