Effect of glycosylation inhibitors on the structure and function of the murine transferrin receptor

Name: Work Video:
Duration: 3 min 30 s
Julie E. Ralton; Heather J. JACKSON; M.G. Zanoni; Paul A. Gleeson
{'id': 'https://openalex.org/W2032681459', 'doi': 'https://doi.org/10.1111/j.1432-1033.1989.tb15254.x', 'title': 'Effect of glycosylation inhibitors on the structure and function of the murine transferrin receptor', 'display_name': 'Effect of glycosylation inhibitors on the structure and function of the murine transferrin receptor', 'publication_year': 1989, 'publication_date': '1989-12-01', 'ids': {'openalex': 'https://openalex.org/W2032681459', 'doi': 'https://doi.org/10.1111/j.1432-1033.1989.tb15254.x', 'mag': '2032681459', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2514095'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1432-1033.1989.tb15254.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1432-1033.1989.tb15254.x', 'source': {'id': 'https://openalex.org/S4210214924', 'display_name': 'European Journal of Biochemistry', 'issn_l': '0014-2956', 'issn': ['0014-2956', '0945-5795', '1432-1033'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1432-1033.1989.tb15254.x', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5008548030', 'display_name': 'Julie E. Ralton', 'orcid': 'https://orcid.org/0000-0002-9536-6253'}, 'institutions': [{'id': 'https://openalex.org/I56590836', 'display_name': 'Monash University', 'ror': 'https://ror.org/02bfwt286', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I56590836']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Julie E. RALTON', 'raw_affiliation_strings': ['Department of Pathology & Immunology, Monash University Medical School Melbourne, Australia'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology & Immunology, Monash University Medical School Melbourne, Australia', 'institution_ids': ['https://openalex.org/I56590836']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111705505', 'display_name': 'Heather J. JACKSON', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I56590836', 'display_name': 'Monash University', 'ror': 'https://ror.org/02bfwt286', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I56590836']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Heather J. JACKSON', 'raw_affiliation_strings': ['Department of Pathology & Immunology, Monash University Medical School Melbourne, Australia'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology & Immunology, Monash University Medical School Melbourne, Australia', 'institution_ids': ['https://openalex.org/I56590836']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5107858668', 'display_name': 'M.G. Zanoni', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I56590836', 'display_name': 'Monash University', 'ror': 'https://ror.org/02bfwt286', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I56590836']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Maureen ZANONI', 'raw_affiliation_strings': ['Department of Pathology & Immunology, Monash University Medical School Melbourne, Australia'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology & Immunology, Monash University Medical School Melbourne, Australia', 'institution_ids': ['https://openalex.org/I56590836']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5090566469', 'display_name': 'Paul A. Gleeson', 'orcid': 'https://orcid.org/0000-0002-5336-6503'}, 'institutions': [{'id': 'https://openalex.org/I56590836', 'display_name': 'Monash University', 'ror': 'https://ror.org/02bfwt286', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I56590836']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Paul A. GLEESON', 'raw_affiliation_strings': ['Department of Pathology & Immunology, Monash University Medical School Melbourne, Australia'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology & Immunology, Monash University Medical School Melbourne, Australia', 'institution_ids': ['https://openalex.org/I56590836']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.976, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 12, 'citation_normalized_percentile': {'value': 0.517516, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 80, 'max': 81}, 'biblio': {'volume': '186', 'issue': '3', 'first_page': '637', 'last_page': '647'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10602', 'display_name': 'Glycosylation and Glycoproteins Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10602', 'display_name': 'Glycosylation and Glycoproteins Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10835', 'display_name': 'Carbohydrate Chemistry and Synthesis', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11016', 'display_name': 'Monoclonal and Polyclonal Antibodies Research', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/castanospermine', 'display_name': 'Castanospermine', 'score': 0.96942234}, {'id': 'https://openalex.org/keywords/tunicamycin', 'display_name': 'Tunicamycin', 'score': 0.9514625}, {'id': 'https://openalex.org/keywords/swainsonine', 'display_name': 'Swainsonine', 'score': 0.83408487}, {'id': 'https://openalex.org/keywords/transferrin-receptor', 'display_name': 'Transferrin receptor', 'score': 0.50941736}, {'id': 'https://openalex.org/keywords/n-linked-glycosylation', 'display_name': 'N-linked glycosylation', 'score': 0.4397605}], 'concepts': [{'id': 'https://openalex.org/C2781060939', 'wikidata': 'https://www.wikidata.org/wiki/Q753104', 'display_name': 'Castanospermine', 'level': 3, 'score': 0.96942234}, {'id': 'https://openalex.org/C2777575526', 'wikidata': 'https://www.wikidata.org/wiki/Q3542091', 'display_name': 'Tunicamycin', 'level': 4, 'score': 0.9514625}, {'id': 'https://openalex.org/C2775928797', 'wikidata': 'https://www.wikidata.org/wiki/Q415324', 'display_name': 'Swainsonine', 'level': 2, 'score': 0.83408487}, {'id': 'https://openalex.org/C19869320', 'wikidata': 'https://www.wikidata.org/wiki/Q419277', 'display_name': 'Concanavalin A', 'level': 3, 'score': 0.7033833}, {'id': 'https://openalex.org/C2777313579', 'wikidata': 'https://www.wikidata.org/wiki/Q898365', 'display_name': 'Glycosylation', 'level': 2, 'score': 0.67422163}, {'id': 'https://openalex.org/C2775887612', 'wikidata': 'https://www.wikidata.org/wiki/Q10809118', 'display_name': 'Mannose', 'level': 2, 'score': 0.6018436}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.5750889}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.53045833}, {'id': 'https://openalex.org/C32264632', 'wikidata': 'https://www.wikidata.org/wiki/Q1134983', 'display_name': 'Transferrin receptor', 'level': 3, 'score': 0.50941736}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.46455497}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.4635799}, {'id': 'https://openalex.org/C30324644', 'wikidata': 'https://www.wikidata.org/wiki/Q3334151', 'display_name': 'N-linked glycosylation', 'level': 4, 'score': 0.4397605}, {'id': 'https://openalex.org/C108625454', 'wikidata': 'https://www.wikidata.org/wiki/Q187126', 'display_name': 'Glycoprotein', 'level': 2, 'score': 0.3965496}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.29639286}, {'id': 'https://openalex.org/C206212055', 'wikidata': 'https://www.wikidata.org/wiki/Q2553138', 'display_name': 'Glycan', 'level': 3, 'score': 0.28232855}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.23211479}, {'id': 'https://openalex.org/C158617107', 'wikidata': 'https://www.wikidata.org/wiki/Q79927', 'display_name': 'Endoplasmic reticulum', 'level': 2, 'score': 0.091006845}, {'id': 'https://openalex.org/C139447449', 'wikidata': 'https://www.wikidata.org/wiki/Q14633900', 'display_name': 'Unfolded protein response', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000470', 'descriptor_name': 'Alkaloids', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D006026', 'descriptor_name': 'Glycoside Hydrolases', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D007212', 'descriptor_name': 'Indolizines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011990', 'descriptor_name': 'Receptors, Transferrin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014415', 'descriptor_name': 'Tunicamycin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D000470', 'descriptor_name': 'Alkaloids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002455', 'descriptor_name': 'Cell Division', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002455', 'descriptor_name': 'Cell Division', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005643', 'descriptor_name': 'Fucose', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005643', 'descriptor_name': 'Fucose', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006020', 'descriptor_name': 'Glycopeptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006020', 'descriptor_name': 'Glycopeptides', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D006026', 'descriptor_name': 'Glycoside Hydrolases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006031', 'descriptor_name': 'Glycosylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008358', 'descriptor_name': 'Mannose', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008358', 'descriptor_name': 'Mannose', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008361', 'descriptor_name': 'Mannosidases', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D008361', 'descriptor_name': 'Mannosidases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008715', 'descriptor_name': 'Methionine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008715', 'descriptor_name': 'Methionine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009363', 'descriptor_name': 'Neoplasm Proteins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D009363', 'descriptor_name': 'Neoplasm Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010954', 'descriptor_name': 'Plasmacytoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011865', 'descriptor_name': 'Radioisotope Dilution Technique', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011990', 'descriptor_name': 'Receptors, Transferrin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011990', 'descriptor_name': 'Receptors, Transferrin', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D011990', 'descriptor_name': 'Receptors, Transferrin', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D013462', 'descriptor_name': 'Sulfur Radioisotopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017026', 'descriptor_name': 'Swainsonine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014316', 'descriptor_name': 'Tritium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014415', 'descriptor_name': 'Tunicamycin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1432-1033.1989.tb15254.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1432-1033.1989.tb15254.x', 'source': {'id': 'https://openalex.org/S4210214924', 'display_name': 'European Journal of Biochemistry', 'issn_l': '0014-2956', 'issn': ['0014-2956', '0945-5795', '1432-1033'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2514095', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1432-1033.1989.tb15254.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1432-1033.1989.tb15254.x', 'source': {'id': 'https://openalex.org/S4210214924', 'display_name': 'European Journal of Biochemistry', 'issn_l': '0014-2956', 'issn': ['0014-2956', '0945-5795', '1432-1033'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 47, 'referenced_works': ['https://openalex.org/W1485388309', 'https://openalex.org/W1486483688', 'https://openalex.org/W1505773153', 'https://openalex.org/W1511330982', 'https://openalex.org/W1512614115', 'https://openalex.org/W1520282358', 'https://openalex.org/W1524991795', 'https://openalex.org/W1543822102', 'https://openalex.org/W1549391316', 'https://openalex.org/W1588683230', 'https://openalex.org/W1591975847', 'https://openalex.org/W1592553645', 'https://openalex.org/W1605980863', 'https://openalex.org/W1815150347', 'https://openalex.org/W1962690668', 'https://openalex.org/W1988158452', 'https://openalex.org/W2009889818', 'https://openalex.org/W2012932147', 'https://openalex.org/W2015113703', 'https://openalex.org/W2015788957', 'https://openalex.org/W2019757220', 'https://openalex.org/W2020437934', 'https://openalex.org/W2031119708', 'https://openalex.org/W2035152288', 'https://openalex.org/W2041034132', 'https://openalex.org/W2043701906', 'https://openalex.org/W2049645388', 'https://openalex.org/W2065047355', 'https://openalex.org/W2070651228', 'https://openalex.org/W2071853137', 'https://openalex.org/W2083830246', 'https://openalex.org/W2083848280', 'https://openalex.org/W2085882979', 'https://openalex.org/W2088599228', 'https://openalex.org/W2095720325', 'https://openalex.org/W2100837269', 'https://openalex.org/W2140277678', 'https://openalex.org/W2140892487', 'https://openalex.org/W2161629160', 'https://openalex.org/W2227071218', 'https://openalex.org/W2313516846', 'https://openalex.org/W2398724578', 'https://openalex.org/W280875868', 'https://openalex.org/W326103902', 'https://openalex.org/W4206701382', 'https://openalex.org/W57809147', 'https://openalex.org/W934245563'], 'related_works': ['https://openalex.org/W2464202189', 'https://openalex.org/W2340807671', 'https://openalex.org/W2137469126', 'https://openalex.org/W2117168010', 'https://openalex.org/W2116068036', 'https://openalex.org/W2048764560', 'https://openalex.org/W2044669462', 'https://openalex.org/W2032681459', 'https://openalex.org/W1974174443', 'https://openalex.org/W1964404605'], 'abstract_inverted_index': {'The': [0, 155, 285], 'murine': [1, 26, 279], 'transferrin': [2, 23, 105, 294], 'receptor': [3, 24, 106, 124, 147, 156, 184, 254, 280, 287, 305], 'is': [4, 281], 'a': [5, 96, 266], 'disulphide‐linked': [6], 'dimer': [7], 'with': [8, 32, 92, 299], 'three': [9], 'N': [10, 118, 151, 165, 170, 223, 249], '‐glycosylation': [11], 'sites.': [12], 'We': [13], 'have': [14], 'investigated': [15], 'the': [16, 22, 33, 38, 99, 104, 123, 130, 183, 219, 245, 253, 271, 304, 311], 'structural': [17], 'and': [18, 37, 42, 69, 82, 110, 168, 179, 198, 225, 258], 'functional': [19], 'properties': [20], 'of': [21, 79, 89, 103, 122, 196, 218, 221, 228, 244, 247, 252, 276, 283, 303, 313], 'from': [25, 107, 125, 157, 185, 255, 288], 'plasmacytoma': [27], 'cells': [28, 52, 81, 91, 127, 159, 187, 261, 290], '(NS‐1': [29], 'cells)': [30], 'treated': [31, 260], 'glycosylation': [34], 'inhibitor,': [35], 'tunicamycin': [36, 93], 'glycosylation‐processing': [39], 'inhibitors,': [40], 'swainsonine': [41, 66, 209, 257, 315], 'castanospermine.': [43], 'Tunicamycin': [44], '(1': [45, 67, 210], 'μg/ml)': [46, 68, 72, 211, 236], 'inhibited': [47, 58], 'mannose': [48, 75], 'incorporation': [49, 60, 76], 'in': [50, 74, 95, 98, 129, 176, 214, 239, 310], 'NS‐1': [51, 90], 'by': [53, 61, 202, 297, 320], '&gt;': [54, 77], '90%,': [55], 'but': [56], 'also': [57], 'me‐thionine': [59], 'up': [62], 'to': [63, 113, 149, 163, 192, 270, 292], '50%.': [64], 'Both': [65], 'castanospermine': [70, 234, 259, 317], '(50': [71], 'resulted': [73, 94, 128, 213, 238], '100%': [78], 'untreated': [80, 126], 'neither': [83], 'drug': [84], 'affected': [85], 'methionine': [86], 'incorporation.': [87], 'Incubation': [88], 'shift': [97], 'apparent': [100], 'molecular': [101], 'mass': [102], '96': [108], 'kDa': [109, 112, 134, 141], '94': [111], 'approximately': [114, 215], '82': [115, 133], 'kDa.': [116], 'Peptide': [117], '‐glycosidase': [119, 152, 166], 'F': [120, 153, 167], 'digestion': [121], 'fully': [131], 'deglycosylated': [132, 146], 'component': [135, 142, 268], 'as': [136, 138, 295, 318], 'well': [137], 'an': [139, 226], '87': [140], 'which': [143], 'represents': [144], 'partially': [145, 190], 'resistant': [148], 'peptide': [150, 164], 'digestion.': [154], 'swainsonine‐treated': [158], 'was': [160, 188, 306], 'equally': [161], 'sensitive': [162, 191], 'endo‐β‐': [169], '‐acetylglucosaminidase': [171], 'H': [172], '(endo': [173], 'H;': [174], 'resulting': [175], 'both': [177], '87‐kDa': [178], '82‐kDa': [180], 'components),': [181], 'whereas': [182], 'castanospermine‐treated': [186], 'only': [189, 240], 'endo': [193], 'H.': [194], 'Analysis': [195, 251], 'mannose‐': [197], 'fucose‐labelled': [199], 'cellular': [200], 'glycopeptides': [201], 'concanavalin‐A': [203], '‐': [204], 'Sepharose': [205], 'chromatography': [206], 'showed': [207, 265], 'that': [208, 274], 'treatment': [212, 237], '90%': [216], 'inhibition': [217, 242], 'synthesis': [220, 246], 'complex': [222, 248], '‐glycans': [224], 'accumulation': [227], 'fucosylated': [229], 'hybrid': [230], 'structures.': [231], 'In': [232], 'contrast,': [233], '(100': [235], 'partial': [241], '(60%)': [243], '‐glycans.': [250], 'tunicamycin,': [256], 'under': [262], 'non‐reducing': [263], 'conditions': [264], 'single': [267], 'corresponding': [269], 'dimer,': [272], 'indicating': [273], 'dimerisation': [275], 'newly': [277], 'synthesisted': [278], 'independent': [282], 'carbohydrate.': [284], 'non‐glycosylated': [286], 'tunicamycin‐treated': [289], 'appears': [291], 'bind': [293], 'demonstrated': [296], 'interaction': [298], 'transferrin‐Sepharose.': [300], 'Surface': [301], 'expression': [302], 'not': [307], 'significantly': [308], 'altered': [309], 'presence': [312], 'either': [314], 'or': [316], 'judged': [319], 'flow': [321], 'cytometry.': [322]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2032681459', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-12-09T23:16:09.588606', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
