Title: Nanogel Star Polymer Architectures: A Nanoparticle Platform for Modular Programmable Macromolecular Self‐Assembly, Intercellular Transport, and Dual‐Mode Cargo Delivery
Abstract: Advanced MaterialsVolume 23, Issue 39 p. 4509-4515 Communication Nanogel Star Polymer Architectures: A Nanoparticle Platform for Modular Programmable Macromolecular Self-Assembly, Intercellular Transport, and Dual-Mode Cargo Delivery Victor Y. Lee, Victor Y. Lee IBM Almaden Research Center, San Jose, CA 95120, USASearch for more papers by this authorKaren Havenstrite, Karen Havenstrite School of Medicine, Stanford University, Stanford, CA 94305, USASearch for more papers by this authorMelia Tjio, Melia Tjio Department of Chemical and Materials Engineering, San Jose State University, San Jose, CA 95192, USASearch for more papers by this authorMelanie McNeil, Melanie McNeil Department of Chemical and Materials Engineering, San Jose State University, San Jose, CA 95192, USASearch for more papers by this authorHelen M. Blau, Helen M. Blau School of Medicine, Stanford University, Stanford, CA 94305, USASearch for more papers by this authorRobert D. Miller, Corresponding Author Robert D. Miller [email protected] IBM Almaden Research Center, San Jose, CA 95120, USAIBM Almaden Research Center, San Jose, CA 95120, USA.Search for more papers by this authorJoseph Sly, Corresponding Author Joseph Sly [email protected] IBM Almaden Research Center, San Jose, CA 95120, USAIBM Almaden Research Center, San Jose, CA 95120, USA.Search for more papers by this author Victor Y. Lee, Victor Y. Lee IBM Almaden Research Center, San Jose, CA 95120, USASearch for more papers by this authorKaren Havenstrite, Karen Havenstrite School of Medicine, Stanford University, Stanford, CA 94305, USASearch for more papers by this authorMelia Tjio, Melia Tjio Department of Chemical and Materials Engineering, San Jose State University, San Jose, CA 95192, USASearch for more papers by this authorMelanie McNeil, Melanie McNeil Department of Chemical and Materials Engineering, San Jose State University, San Jose, CA 95192, USASearch for more papers by this authorHelen M. Blau, Helen M. Blau School of Medicine, Stanford University, Stanford, CA 94305, USASearch for more papers by this authorRobert D. Miller, Corresponding Author Robert D. Miller [email protected] IBM Almaden Research Center, San Jose, CA 95120, USAIBM Almaden Research Center, San Jose, CA 95120, USA.Search for more papers by this authorJoseph Sly, Corresponding Author Joseph Sly [email protected] IBM Almaden Research Center, San Jose, CA 95120, USAIBM Almaden Research Center, San Jose, CA 95120, USA.Search for more papers by this author First published: 08 September 2011 https://doi.org/10.1002/adma.201102371Citations: 43Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Graphical Abstract Nanogel star polymers are developed as a new route for the formation of dual-mode nanoparticle systems for applications in the areas of synergistic therapeutic delivery, imaged therapeutic delivery, and dual-mode bioimaging agents. These extremely uniform, structurally versatile, water-soluble, unimolecular organic nanoparticles with tunable polyvalency and functionality are preprogrammed to spontaneously upload different types of complex functional macromolecules. References 1 E.-K. Lim, Y.-M. H. J. Yang, K. Lee, J.-S. Suh, S. Haam, Adv. Mater. 2011, 23, 2426. 2 S. M. Janib, A. S. Moses, J. A. Mackay, Adv. Drug Delivery Rev. 2010, 62, 1052. 3 R. Hao, R. Xing, Z. Xu, Y. Hou, S. Gao, S. Sun, Adv. Mater. 2010, 22, 2729. 4 P. Horcajada, T. Chalati, C. Serre, B. Gillet, C. Sebrie, T. Baati, J. F. Eubank, D. Heurtaux, P. Clayette, C. Kreuz, J.-S. Chang, Y. Hwang, V. Marsaud, P.-N. Bories, L. Cynober, S. Gil, G. Férey, P. Couvreur, R. 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