Title: Incidence of helicobacter pylori antibiotic resistance and relationship to age, sex and socio-economic status
Abstract: Background: The proportion of H. pylori-negative (Hp-ve) duodenal ulcer disease appears to be increasing.Data on clinical outcome and prognosis in this subgroup are lacking.Methods: 276 duodenal ulcer patients randomized to either eradication therapy or maintenance omeprazole (doubleblind, double-dummy design) for 1 year were studied.Patients were followed up for 2 years with visits performed every 2 months the first year and every 6 months for the following year.Hp status was assessed by