Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2031116189', 'doi': 'https://doi.org/10.1248/bpb.31.336', 'title': 'Determination of Albumin in Bronchoalveolar Lavage Fluid by Flow-Injection Fluorometry Using Chromazurol S', 'display_name': 'Determination of Albumin in Bronchoalveolar Lavage Fluid by Flow-Injection Fluorometry Using Chromazurol S', 'publication_year': 2008, 'publication_date': '2008-01-01', 'ids': {'openalex': 'https://openalex.org/W2031116189', 'doi': 'https://doi.org/10.1248/bpb.31.336', 'mag': '2031116189', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18310888'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1248/bpb.31.336', 'pdf_url': 'https://www.jstage.jst.go.jp/article/bpb/31/3/31_3_336/_pdf', 'source': {'id': 'https://openalex.org/S165235614', 'display_name': 'Biological and Pharmaceutical Bulletin', 'issn_l': '0918-6158', 'issn': ['0918-6158', '1347-5215'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313382', 'host_organization_name': 'Pharmaceutical Society of Japan', 'host_organization_lineage': ['https://openalex.org/P4310313382'], 'host_organization_lineage_names': ['Pharmaceutical Society of Japan'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.jstage.jst.go.jp/article/bpb/31/3/31_3_336/_pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5103370517', 'display_name': 'Takaji Sato', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I90237989', 'display_name': 'Osaka University of Pharmaceutical Sciences', 'ror': 'https://ror.org/029yaft79', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I90237989']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takaji Sato', 'raw_affiliation_strings': ['Osaka University of Pharmaceutical Sciences'], 'affiliations': [{'raw_affiliation_string': 'Osaka University of Pharmaceutical Sciences', 'institution_ids': ['https://openalex.org/I90237989']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025802848', 'display_name': 'Yoshihiro Saito', 'orcid': 'https://orcid.org/0000-0002-3955-2684'}, 'institutions': [{'id': 'https://openalex.org/I90237989', 'display_name': 'Osaka University of Pharmaceutical Sciences', 'ror': 'https://ror.org/029yaft79', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I90237989']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yoshihiro Saito', 'raw_affiliation_strings': ['Osaka University of Pharmaceutical Sciences'], 'affiliations': [{'raw_affiliation_string': 'Osaka University of Pharmaceutical Sciences', 'institution_ids': ['https://openalex.org/I90237989']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010700178', 'display_name': 'Masahiko Chikuma', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I90237989', 'display_name': 'Osaka University of Pharmaceutical Sciences', 'ror': 'https://ror.org/029yaft79', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I90237989']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Masahiko Chikuma', 'raw_affiliation_strings': ['Osaka University of Pharmaceutical Sciences'], 'affiliations': [{'raw_affiliation_string': 'Osaka University of Pharmaceutical Sciences', 'institution_ids': ['https://openalex.org/I90237989']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046786824', 'display_name': 'Yutaka Saito', 'orcid': 'https://orcid.org/0000-0003-2296-8373'}, 'institutions': [{'id': 'https://openalex.org/I163770644', 'display_name': 'Okayama University', 'ror': 'https://ror.org/02pc6pc55', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I163770644']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yutaka Saito', 'raw_affiliation_strings': ['Department of Pharmaceutical Sciences, Graduate School of Medicine and Dentistry and Pharmaceutical Sciences, Okayama University'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmaceutical Sciences, Graduate School of Medicine and Dentistry and Pharmaceutical Sciences, Okayama University', 'institution_ids': ['https://openalex.org/I163770644']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111727403', 'display_name': 'Sonoko Nagai', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I22299242', 'display_name': 'Kyoto University', 'ror': 'https://ror.org/02kpeqv85', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I22299242']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Sonoko Nagai', 'raw_affiliation_strings': ['Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University'], 'affiliations': [{'raw_affiliation_string': 'Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University', 'institution_ids': ['https://openalex.org/I22299242']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.266, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 7, 'citation_normalized_percentile': {'value': 0.747069, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 81, 'max': 82}, 'biblio': {'volume': '31', 'issue': '3', 'first_page': '336', 'last_page': '339'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11651', 'display_name': 'Inhalation and Respiratory Drug Delivery', 'score': 0.9908, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11651', 'display_name': 'Inhalation and Respiratory Drug Delivery', 'score': 0.9908, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11189', 'display_name': 'Transplantation: Methods and Outcomes', 'score': 0.9747, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10051', 'display_name': 'Asthma and respiratory diseases', 'score': 0.9731, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2777961210', 'wikidata': 'https://www.wikidata.org/wiki/Q927148', 'display_name': 'Bronchoalveolar lavage', 'level': 3, 'score': 0.89822394}, {'id': 'https://openalex.org/C158711907', 'wikidata': 'https://www.wikidata.org/wiki/Q1768467', 'display_name': 'Fluorescence spectroscopy', 'level': 3, 'score': 0.6072836}, {'id': 'https://openalex.org/C2776125364', 'wikidata': 'https://www.wikidata.org/wiki/Q169219', 'display_name': 'Albumin', 'level': 2, 'score': 0.59732115}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.48870042}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.39921063}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.39072737}, {'id': 'https://openalex.org/C91881484', 'wikidata': 'https://www.wikidata.org/wiki/Q191807', 'display_name': 'Fluorescence', 'level': 2, 'score': 0.20555383}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.19053406}, {'id': 'https://openalex.org/C2777714996', 'wikidata': 'https://www.wikidata.org/wiki/Q7886', 'display_name': 'Lung', 'level': 2, 'score': 0.08609474}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C62520636', 'wikidata': 'https://www.wikidata.org/wiki/Q944', 'display_name': 'Quantum mechanics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000418', 'descriptor_name': 'Albumins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D001992', 'descriptor_name': 'Bronchoalveolar Lavage Fluid', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D062385', 'descriptor_name': 'Hydroxybenzoates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000418', 'descriptor_name': 'Albumins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001992', 'descriptor_name': 'Bronchoalveolar Lavage Fluid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017022', 'descriptor_name': 'Flow Injection Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005470', 'descriptor_name': 'Fluorometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007202', 'descriptor_name': 'Indicators and Reagents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011658', 'descriptor_name': 'Pulmonary Fibrosis', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D011658', 'descriptor_name': 'Pulmonary Fibrosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015203', 'descriptor_name': 'Reproducibility of Results', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017565', 'descriptor_name': 'Sarcoidosis, Pulmonary', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D017565', 'descriptor_name': 'Sarcoidosis, Pulmonary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012680', 'descriptor_name': 'Sensitivity and Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1248/bpb.31.336', 'pdf_url': 'https://www.jstage.jst.go.jp/article/bpb/31/3/31_3_336/_pdf', 'source': {'id': 'https://openalex.org/S165235614', 'display_name': 'Biological and Pharmaceutical Bulletin', 'issn_l': '0918-6158', 'issn': ['0918-6158', '1347-5215'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313382', 'host_organization_name': 'Pharmaceutical Society of Japan', 'host_organization_lineage': ['https://openalex.org/P4310313382'], 'host_organization_lineage_names': ['Pharmaceutical Society of Japan'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18310888', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1248/bpb.31.336', 'pdf_url': 'https://www.jstage.jst.go.jp/article/bpb/31/3/31_3_336/_pdf', 'source': {'id': 'https://openalex.org/S165235614', 'display_name': 'Biological and Pharmaceutical Bulletin', 'issn_l': '0918-6158', 'issn': ['0918-6158', '1347-5215'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313382', 'host_organization_name': 'Pharmaceutical Society of Japan', 'host_organization_lineage': ['https://openalex.org/P4310313382'], 'host_organization_lineage_names': ['Pharmaceutical Society of Japan'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.45, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 15, 'referenced_works': ['https://openalex.org/W1709830154', 'https://openalex.org/W1962850382', 'https://openalex.org/W2025683601', 'https://openalex.org/W2027073728', 'https://openalex.org/W2027825067', 'https://openalex.org/W2043068531', 'https://openalex.org/W2066633143', 'https://openalex.org/W2068948874', 'https://openalex.org/W2073839443', 'https://openalex.org/W2078066842', 'https://openalex.org/W2148779349', 'https://openalex.org/W2268426516', 'https://openalex.org/W2333507474', 'https://openalex.org/W2409726975', 'https://openalex.org/W4234107586'], 'related_works': ['https://openalex.org/W4387497383', 'https://openalex.org/W2948807893', 'https://openalex.org/W2778153218', 'https://openalex.org/W2748952813', 'https://openalex.org/W2527526854', 'https://openalex.org/W2078814861', 'https://openalex.org/W2062208111', 'https://openalex.org/W1986764834', 'https://openalex.org/W1976181487', 'https://openalex.org/W1531601525'], 'abstract_inverted_index': {'A': [0, 51], 'highly': [1, 52], 'sensitive': [2, 167], 'flow': [3, 90, 150], 'injection': [4, 91, 151], 'fluorometry': [5], 'for': [6, 143], 'the': [7, 16, 44, 59, 68, 88, 95, 133, 156], 'determination': [8, 17, 134, 157], 'of': [9, 18, 32, 46, 49, 135, 158], 'albumin': [10, 19, 60, 100, 113, 136, 160], 'was': [11, 41, 56, 85, 109], 'developed': [12], 'and': [13, 71, 123, 147, 168], 'applied': [14], 'to': [15, 36], 'in': [20, 43, 62, 87, 94, 102, 115, 138, 155, 161], 'human': [21], 'bronchoalveolar': [22], 'lavage': [23], 'fluids': [24], '(BALF).': [25], 'This': [26, 129], 'method': [27, 70, 76, 92, 152], 'is': [28, 141, 153, 166], 'based': [29], 'on': [30], 'binding': [31], 'chromazurol': [33], 'S': [34], '(CAS)': [35], 'albumin.': [37, 50], 'The': [38, 82, 99, 112], 'calibration': [39], 'curve': [40], 'linear': [42, 53], 'range': [45], '5-200': [47], 'microg/ml': [48], 'correlation': [54], '(r=0.986)': [55], 'observed': [57], 'between': [58], 'level': [61, 101], 'BALF': [63, 103, 116, 139, 162], 'samples': [64, 117, 140], '(n=25)': [65], 'determined': [66], 'by': [67, 72], 'proposed': [69], 'a': [73], 'conventional': [74], 'fluorometric': [75], 'using': [77], 'CAS': [78, 89, 96, 149], '(CAS': [79], 'manual': [80, 97], 'method).': [81], 'IgG': [83], 'interference': [84], 'lower': [86], 'than': [93], 'method.': [98], 'collected': [104], 'from': [105, 119], 'healthy': [106], 'volunteers': [107], '(n=10)': [108], '58.5+/-13.1': [110], 'microg/ml.': [111], 'levels': [114, 137], 'obtained': [118], 'patients': [120], 'with': [121], 'sarcoidosis': [122], 'idiopathic': [124], 'pulmonary': [125], 'fibrosis': [126], 'were': [127], 'increased.': [128], 'finding': [130], 'shows': [131], 'that': [132, 148], 'useful': [142], 'investigating': [144], 'lung': [145], 'diseases': [146], 'promising': [154], 'trace': [159], 'samples,': [163], 'because': [164], 'it': [165], 'precise.': [169]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2031116189', 'counts_by_year': [{'year': 2020, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-12-17T02:15:03.415665', 'created_date': '2016-06-24'}