Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2030726203', 'doi': 'https://doi.org/10.1016/j.tiv.2010.01.005', 'title': 'Calcium signals and caspase-12 participated in paraoxon-induced apoptosis in EL4 cells', 'display_name': 'Calcium signals and caspase-12 participated in paraoxon-induced apoptosis in EL4 cells', 'publication_year': 2010, 'publication_date': '2010-01-18', 'ids': {'openalex': 'https://openalex.org/W2030726203', 'doi': 'https://doi.org/10.1016/j.tiv.2010.01.005', 'mag': '2030726203', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20079824'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.tiv.2010.01.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S39580544', 'display_name': 'Toxicology in Vitro', 'issn_l': '0887-2333', 'issn': ['0887-2333', '1879-3177'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100373019', 'display_name': 'Lan Li', 'orcid': 'https://orcid.org/0000-0002-4635-6331'}, 'institutions': [{'id': 'https://openalex.org/I76214153', 'display_name': 'Lanzhou University', 'ror': 'https://ror.org/01mkqqe32', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76214153']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lan Li', 'raw_affiliation_strings': ['School of Life Sciences, Lanzhou University Lanzhou 730000, PR China.'], 'affiliations': [{'raw_affiliation_string': 'School of Life Sciences, Lanzhou University Lanzhou 730000, PR China.', 'institution_ids': ['https://openalex.org/I76214153']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070589690', 'display_name': 'Zhiheng Cao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I76214153', 'display_name': 'Lanzhou University', 'ror': 'https://ror.org/01mkqqe32', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76214153']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhiheng Cao', 'raw_affiliation_strings': ['School of Life Sciences, Lanzhou University Lanzhou 730000, PR China.'], 'affiliations': [{'raw_affiliation_string': 'School of Life Sciences, Lanzhou University Lanzhou 730000, PR China.', 'institution_ids': ['https://openalex.org/I76214153']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102221841', 'display_name': 'Pengfei Jia', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I76214153', 'display_name': 'Lanzhou University', 'ror': 'https://ror.org/01mkqqe32', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76214153']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Pengfei Jia', 'raw_affiliation_strings': ['School of Life Sciences, Lanzhou University Lanzhou 730000, PR China.'], 'affiliations': [{'raw_affiliation_string': 'School of Life Sciences, Lanzhou University Lanzhou 730000, PR China.', 'institution_ids': ['https://openalex.org/I76214153']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5065154754', 'display_name': 'Ziren Wang', 'orcid': 'https://orcid.org/0000-0002-8227-8959'}, 'institutions': [{'id': 'https://openalex.org/I76214153', 'display_name': 'Lanzhou University', 'ror': 'https://ror.org/01mkqqe32', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I76214153']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ziren Wang', 'raw_affiliation_strings': ['School of Life Sciences, Lanzhou University Lanzhou 730000, PR China.'], 'affiliations': [{'raw_affiliation_string': 'School of Life Sciences, Lanzhou University Lanzhou 730000, PR China.', 'institution_ids': ['https://openalex.org/I76214153']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3910, 'currency': 'USD', 'value_usd': 3910, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.666, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 9, 'citation_normalized_percentile': {'value': 0.608068, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 83, 'max': 84}, 'biblio': {'volume': '24', 'issue': '3', 'first_page': '728', 'last_page': '736'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10294', 'display_name': 'Cell death mechanisms and regulation', 'score': 0.9899, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10294', 'display_name': 'Cell death mechanisms and regulation', 'score': 0.9899, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11150', 'display_name': 'Endoplasmic Reticulum Stress and Disease', 'score': 0.9814, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12975', 'display_name': 'Paraoxonase enzyme and polymorphisms', 'score': 0.9737, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/paraoxon', 'display_name': 'Paraoxon', 'score': 0.85191554}], 'concepts': [{'id': 'https://openalex.org/C2777207434', 'wikidata': 'https://www.wikidata.org/wiki/Q416108', 'display_name': 'Paraoxon', 'level': 4, 'score': 0.85191554}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.7611834}, {'id': 'https://openalex.org/C519063684', 'wikidata': 'https://www.wikidata.org/wiki/Q706', 'display_name': 'Calcium', 'level': 2, 'score': 0.6590855}, {'id': 'https://openalex.org/C98424977', 'wikidata': 'https://www.wikidata.org/wiki/Q25805', 'display_name': 'Caspase', 'level': 4, 'score': 0.6325604}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.46880797}, {'id': 'https://openalex.org/C12519072', 'wikidata': 'https://www.wikidata.org/wiki/Q14914370', 'display_name': 'Caspase 3', 'level': 4, 'score': 0.46339944}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.44608983}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.28126138}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.27577305}, {'id': 'https://openalex.org/C31573885', 'wikidata': 'https://www.wikidata.org/wiki/Q304484', 'display_name': 'Programmed cell death', 'level': 3, 'score': 0.24638194}, {'id': 'https://openalex.org/C2778816929', 'wikidata': 'https://www.wikidata.org/wiki/Q22676679', 'display_name': 'Acetylcholinesterase', 'level': 3, 'score': 0.1676977}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.16181436}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D020013', 'descriptor_name': 'Calcium Signaling', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D053454', 'descriptor_name': 'Caspase 12', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D007306', 'descriptor_name': 'Insecticides', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D010261', 'descriptor_name': 'Paraoxon', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015220', 'descriptor_name': 'Calcium Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015220', 'descriptor_name': 'Calcium Channels', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D020013', 'descriptor_name': 'Calcium Signaling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053454', 'descriptor_name': 'Caspase 12', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D053454', 'descriptor_name': 'Caspase 12', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002614', 'descriptor_name': 'Chelating Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D002614', 'descriptor_name': 'Chelating Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004533', 'descriptor_name': 'Egtazic Acid', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D004533', 'descriptor_name': 'Egtazic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004721', 'descriptor_name': 'Endoplasmic Reticulum', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D004721', 'descriptor_name': 'Endoplasmic Reticulum', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004721', 'descriptor_name': 'Endoplasmic Reticulum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006493', 'descriptor_name': 'Heparin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D006493', 'descriptor_name': 'Heparin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053496', 'descriptor_name': 'Inositol 1,4,5-Trisphosphate Receptors', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D053496', 'descriptor_name': 'Inositol 1,4,5-Trisphosphate Receptors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007306', 'descriptor_name': 'Insecticides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010261', 'descriptor_name': 'Paraoxon', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011343', 'descriptor_name': 'Procaine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D011343', 'descriptor_name': 'Procaine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019837', 'descriptor_name': 'Ryanodine Receptor Calcium Release Channel', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D019837', 'descriptor_name': 'Ryanodine Receptor Calcium Release Channel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.tiv.2010.01.005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S39580544', 'display_name': 'Toxicology in Vitro', 'issn_l': '0887-2333', 'issn': ['0887-2333', '1879-3177'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20079824', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.46, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 54, 'referenced_works': ['https://openalex.org/W1542639123', 'https://openalex.org/W1967451252', 'https://openalex.org/W1968772834', 'https://openalex.org/W1971320218', 'https://openalex.org/W1974980101', 'https://openalex.org/W1979972336', 'https://openalex.org/W1981608433', 'https://openalex.org/W1987691932', 'https://openalex.org/W1994811478', 'https://openalex.org/W1997005484', 'https://openalex.org/W1999349182', 'https://openalex.org/W1999469541', 'https://openalex.org/W2001162182', 'https://openalex.org/W2001184859', 'https://openalex.org/W2002208801', 'https://openalex.org/W2003432129', 'https://openalex.org/W2006289026', 'https://openalex.org/W2006384362', 'https://openalex.org/W2014100516', 'https://openalex.org/W2015768084', 'https://openalex.org/W2022412065', 'https://openalex.org/W2030842083', 'https://openalex.org/W2034213169', 'https://openalex.org/W2036595429', 'https://openalex.org/W2040877289', 'https://openalex.org/W2042859546', 'https://openalex.org/W2048619984', 'https://openalex.org/W2048975837', 'https://openalex.org/W2052947854', 'https://openalex.org/W2065849060', 'https://openalex.org/W2070433129', 'https://openalex.org/W2072881240', 'https://openalex.org/W2080164857', 'https://openalex.org/W2080913553', 'https://openalex.org/W2086152985', 'https://openalex.org/W2090304479', 'https://openalex.org/W2090804167', 'https://openalex.org/W2097222331', 'https://openalex.org/W2110718102', 'https://openalex.org/W2114263369', 'https://openalex.org/W2114280450', 'https://openalex.org/W2126376871', 'https://openalex.org/W2140872647', 'https://openalex.org/W2142756896', 'https://openalex.org/W2142769269', 'https://openalex.org/W2143492413', 'https://openalex.org/W2152522654', 'https://openalex.org/W2157574938', 'https://openalex.org/W2158114348', 'https://openalex.org/W2257040116', 'https://openalex.org/W2383535828', 'https://openalex.org/W2410537699', 'https://openalex.org/W2412238260', 'https://openalex.org/W2417721384'], 'related_works': ['https://openalex.org/W3142839065', 'https://openalex.org/W2388316603', 'https://openalex.org/W2357228307', 'https://openalex.org/W2120753181', 'https://openalex.org/W2066782359', 'https://openalex.org/W2042949990', 'https://openalex.org/W2029377139', 'https://openalex.org/W2020987091', 'https://openalex.org/W1980109110', 'https://openalex.org/W1979154669'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2030726203', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-16T12:22:27.508118', 'created_date': '2016-06-24'}