Publication Information

{'id': 'https://openalex.org/W2030644390', 'doi': 'https://doi.org/10.1111/j.1574-6968.2006.00404.x', 'title': 'IdeE, an IgG-endopeptidase of<i>Streptococcus equi</i>ssp.<i>equi</i>', 'display_name': 'IdeE, an IgG-endopeptidase of<i>Streptococcus equi</i>ssp.<i>equi</i>', 'publication_year': 2006, 'publication_date': '2006-08-02', 'ids': {'openalex': 'https://openalex.org/W2030644390', 'doi': 'https://doi.org/10.1111/j.1574-6968.2006.00404.x', 'mag': '2030644390', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16923080'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1574-6968.2006.00404.x', 'pdf_url': 'https://academic.oup.com/femsle/article-pdf/262/2/230/19603401/262-2-230.pdf', 'source': {'id': 'https://openalex.org/S34954451', 'display_name': 'FEMS Microbiology Letters', 'issn_l': '0378-1097', 'issn': ['0378-1097', '1574-6968'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://academic.oup.com/femsle/article-pdf/262/2/230/19603401/262-2-230.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5113538751', 'display_name': 'Jonas Lannergård', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I298625061', 'display_name': 'Swedish University of Agricultural Sciences', 'ror': 'https://ror.org/02yy8x990', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I298625061']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Jonas Lannergård', 'raw_affiliation_strings': ['Department of Microbiology Swedish University of Agricultural Sciences Uppsala Sweden'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology Swedish University of Agricultural Sciences Uppsala Sweden', 'institution_ids': ['https://openalex.org/I298625061']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5008166970', 'display_name': 'Bengt Guss', 'orcid': 'https://orcid.org/0000-0002-7044-0701'}, 'institutions': [{'id': 'https://openalex.org/I298625061', 'display_name': 'Swedish University of Agricultural Sciences', 'ror': 'https://ror.org/02yy8x990', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I298625061']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Bengt Guss', 'raw_affiliation_strings': ['Department of Microbiology Swedish University of Agricultural Sciences Uppsala Sweden'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology Swedish University of Agricultural Sciences Uppsala Sweden', 'institution_ids': ['https://openalex.org/I298625061']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2686, 'currency': 'GBP', 'value_usd': 3294, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.949, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 50, 'citation_normalized_percentile': {'value': 0.919763, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '262', 'issue': '2', 'first_page': '230', 'last_page': '235'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11153', 'display_name': 'Streptococcal Infections and Treatments', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11153', 'display_name': 'Streptococcal Infections and Treatments', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11961', 'display_name': 'Neonatal and Maternal Infections', 'score': 0.9872, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10195', 'display_name': 'Antimicrobial Resistance in Staphylococcus', 'score': 0.986, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/streptococcus-equi', 'display_name': 'Streptococcus equi', 'score': 0.9244048}, {'id': 'https://openalex.org/keywords/proteolysis', 'display_name': 'Proteolysis', 'score': 0.54886097}], 'concepts': [{'id': 'https://openalex.org/C2908622527', 'wikidata': 'https://www.wikidata.org/wiki/Q1430934', 'display_name': 'Streptococcus equi', 'level': 3, 'score': 0.9244048}, {'id': 'https://openalex.org/C2780762169', 'wikidata': 'https://www.wikidata.org/wiki/Q5905368', 'display_name': 'Horse', 'level': 2, 'score': 0.620118}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.57995}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.5490362}, {'id': 'https://openalex.org/C2781307694', 'wikidata': 'https://www.wikidata.org/wiki/Q33123', 'display_name': 'Proteolysis', 'level': 3, 'score': 0.54886097}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.50982803}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.50876385}, {'id': 'https://openalex.org/C2780898057', 'wikidata': 'https://www.wikidata.org/wiki/Q79448', 'display_name': 'Immunoglobulin G', 'level': 3, 'score': 0.47356045}, {'id': 'https://openalex.org/C2776714187', 'wikidata': 'https://www.wikidata.org/wiki/Q212410', 'display_name': 'Protease', 'level': 3, 'score': 0.44561836}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.37475717}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.34058222}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.24828172}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.23825878}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.20563564}, {'id': 'https://openalex.org/C151730666', 'wikidata': 'https://www.wikidata.org/wiki/Q7205', 'display_name': 'Paleontology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D007074', 'descriptor_name': 'Immunoglobulin G', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D018502', 'descriptor_name': 'Streptococcus equi', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004591', 'descriptor_name': 'Electrophoresis, Polyacrylamide Gel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005798', 'descriptor_name': 'Genes, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006736', 'descriptor_name': 'Horses', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006736', 'descriptor_name': 'Horses', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D007074', 'descriptor_name': 'Immunoglobulin G', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008322', 'descriptor_name': 'Mammals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008322', 'descriptor_name': 'Mammals', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013058', 'descriptor_name': 'Mass Spectrometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016133', 'descriptor_name': 'Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D044967', 'descriptor_name': 'Serum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018502', 'descriptor_name': 'Streptococcus equi', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D018502', 'descriptor_name': 'Streptococcus equi', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013379', 'descriptor_name': 'Substrate Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1574-6968.2006.00404.x', 'pdf_url': 'https://academic.oup.com/femsle/article-pdf/262/2/230/19603401/262-2-230.pdf', 'source': {'id': 'https://openalex.org/S34954451', 'display_name': 'FEMS Microbiology Letters', 'issn_l': '0378-1097', 'issn': ['0378-1097', '1574-6968'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16923080', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1574-6968.2006.00404.x', 'pdf_url': 'https://academic.oup.com/femsle/article-pdf/262/2/230/19603401/262-2-230.pdf', 'source': {'id': 'https://openalex.org/S34954451', 'display_name': 'FEMS Microbiology Letters', 'issn_l': '0378-1097', 'issn': ['0378-1097', '1574-6968'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 18, 'referenced_works': ['https://openalex.org/W1801667322', 'https://openalex.org/W1969022131', 'https://openalex.org/W1970759336', 'https://openalex.org/W1995030682', 'https://openalex.org/W1995693274', 'https://openalex.org/W2002100123', 'https://openalex.org/W2047875207', 'https://openalex.org/W2088076848', 'https://openalex.org/W2095079710', 'https://openalex.org/W2104017250', 'https://openalex.org/W2111538629', 'https://openalex.org/W2123060283', 'https://openalex.org/W2125545709', 'https://openalex.org/W2149910352', 'https://openalex.org/W2165521792', 'https://openalex.org/W2167655086', 'https://openalex.org/W2171100726', 'https://openalex.org/W4235866557'], 'related_works': ['https://openalex.org/W4214661119', 'https://openalex.org/W3183742356', 'https://openalex.org/W3102935653', 'https://openalex.org/W2429296518', 'https://openalex.org/W2399537989', 'https://openalex.org/W2188933794', 'https://openalex.org/W2158630561', 'https://openalex.org/W2111895380', 'https://openalex.org/W2065213859', 'https://openalex.org/W108022468'], 'abstract_inverted_index': {'Streptococcus': [0, 40], 'equi': [1, 3, 61, 139, 141, 197], 'ssp.': [2, 62, 140, 198], 'is': [4, 46, 107, 135, 142], 'the': [5, 17, 27, 34, 49, 53, 57, 67, 87, 96, 119, 145, 158, 165, 172, 192], 'causative': [6], 'agent': [7], 'of': [8, 21, 29, 33, 39, 44, 51, 56, 66, 70, 80, 90, 98, 147, 160, 174, 187, 195], 'strangles,': [9], 'a': [10, 31, 78, 128, 182], 'highly': [11], 'contagious': [12], 'and': [13, 73], 'serious': [14], 'disease': [15], 'in': [16, 123, 144, 191], 'upper': [18], 'respiratory': [19], 'tract': [20], 'horses.': [22], 'The': [23, 42], 'present': [24], 'study': [25, 65], 'describes': [26], 'characterization': [28], 'IdeE,': [30], 'homolog': [32], 'secreted': [35], 'IgG-specific': [36], 'protease': [37], 'IdeS/Mac': [38, 91], 'pyogenes.': [41], 'activity': [43, 50, 69, 167], 'IdeE': [45, 72], 'compared': [47], 'with': [48, 154], 'IdeZ,': [52], 'corresponding': [54], 'enzyme': [55, 177], 'closely': [58], 'related': [59], 'S.': [60, 138, 196], 'zooepidemicus.': [63, 199], 'A': [64], 'proteolytic': [68], 'recombinant': [71], 'IdeZ': [74], 'on': [75], 'IgG': [76, 104, 112, 121, 162, 188], 'from': [77, 105, 113], 'selection': [79], 'mammals': [81], 'shows': [82], 'that': [83, 95], 'only': [84], 'antibodies': [85], 'containing': [86], 'substrate': [88, 130], 'site': [89, 131], 'are': [92, 101], 'cleaved,': [93], 'indicating': [94], 'specificities': [97], 'these': [99], 'enzymes': [100], 'similar.': [102], 'Interestingly,': [103], 'horse': [106, 124, 148], 'less': [108], 'effectively': [109], 'cleaved': [110], 'than': [111, 179], 'e.g.': [114], 'dog': [115], 'or': [116], 'humans,': [117], 'as': [118], 'dominating': [120], 'isotype': [122], 'sera': [125], '(IgG4)': [126], 'lacks': [127], 'distinct': [129], 'for': [132], 'IdeE/IdeZ.': [133], 'IgG-degradation': [134], 'observed': [136, 166], 'when': [137, 152], 'grown': [143, 153], 'presence': [146], 'serum,': [149], 'but': [150], 'not': [151], 'purified': [155], 'IgG.': [156], 'As': [157], 'fraction': [159], 'degraded': [161], 'contains': [163], 'IgG4,': [164], 'might': [168], 'be': [169], 'due': [170], 'to': [171], 'expression': [173], 'an': [175], 'unknown': [176], 'rather': [178], 'IdeE.': [180], 'In': [181], 'similar': [183], 'assay,': [184], 'no': [185], 'proteolysis': [186], 'was': [189], 'detected': [190], 'growth': [193], 'media': [194]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2030644390', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-12-14T01:47:35.253660', 'created_date': '2016-06-24'}