Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2030588833', 'doi': 'https://doi.org/10.1242/jcs.138578', 'title': 'Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors', 'display_name': 'Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors', 'publication_year': 2013, 'publication_date': '2013-01-01', 'ids': {'openalex': 'https://openalex.org/W2030588833', 'doi': 'https://doi.org/10.1242/jcs.138578', 'mag': '2030588833', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24046449', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3828596'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1242/jcs.138578', 'pdf_url': 'https://jcs.biologists.org/content/joces/126/22/5305.full.pdf', 'source': {'id': 'https://openalex.org/S5677253', 'display_name': 'Journal of Cell Science', 'issn_l': '0021-9533', 'issn': ['0021-9533', '1477-9137'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://jcs.biologists.org/content/joces/126/22/5305.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5086721384', 'display_name': 'Ryan J. Park', 'orcid': 'https://orcid.org/0000-0003-4725-2937'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}, {'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ryan Park', 'raw_affiliation_strings': ['Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA', 'Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06510, USA', 'Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA', 'Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT 06510, USA', 'Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06510, USA'], 'affiliations': [{'raw_affiliation_string': 'Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I1344073410', 'https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005621524', 'display_name': 'Haihong Shen', 'orcid': 'https://orcid.org/0000-0002-2115-7037'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}, {'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hongying Shen', 'raw_affiliation_strings': ['Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA', 'Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06510, USA', 'Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA', 'Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT 06510, USA', 'Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06510, USA'], 'affiliations': [{'raw_affiliation_string': 'Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I1344073410', 'https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100343788', 'display_name': 'Lijuan Liu', 'orcid': 'https://orcid.org/0000-0003-1138-5543'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lijuan Liu', 'raw_affiliation_strings': ['Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA', 'Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT 06510, USA', 'Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06510, USA'], 'affiliations': [{'raw_affiliation_string': 'Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100782677', 'display_name': 'Xinran Liu', 'orcid': 'https://orcid.org/0000-0002-1586-2151'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Xinran Liu', 'raw_affiliation_strings': ['Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091271525', 'display_name': 'Shawn M. Ferguson', 'orcid': 'https://orcid.org/0000-0002-3092-7718'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Shawn M. Ferguson', 'raw_affiliation_strings': ['Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA', 'Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06510, USA'], 'affiliations': [{'raw_affiliation_string': 'Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5037459294', 'display_name': 'Pietro De Camilli', 'orcid': 'https://orcid.org/0000-0001-9045-0723'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}, {'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Pietro De Camilli', 'raw_affiliation_strings': ['Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA', 'Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06510, USA', 'Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA', 'Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT 06510, USA', 'Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06510, USA'], 'affiliations': [{'raw_affiliation_string': 'Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I1344073410', 'https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA', 'institution_ids': ['https://openalex.org/I32971472']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 9.908, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 232, 'citation_normalized_percentile': {'value': 0.885754, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10617', 'display_name': 'Mechanisms of Intracellular Membrane Trafficking', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10617', 'display_name': 'Mechanisms of Intracellular Membrane Trafficking', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12286', 'display_name': 'Mechanosensitive Ion Channels in Physiology and Disease', 'score': 0.9746, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10691', 'display_name': 'Molecular Mechanisms of Retinal Degeneration and Regeneration', 'score': 0.971, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dynamin', 'display_name': 'Dynamin', 'score': 0.546075}, {'id': 'https://openalex.org/keywords/membrane-ruffling', 'display_name': 'Membrane ruffling', 'score': 0.5394012}, {'id': 'https://openalex.org/keywords/knockout-mouse', 'display_name': 'Knockout mouse', 'score': 0.47471133}], 'concepts': [{'id': 'https://openalex.org/C156407911', 'wikidata': 'https://www.wikidata.org/wiki/Q420160', 'display_name': 'Dynamin', 'level': 4, 'score': 0.99330056}, {'id': 'https://openalex.org/C28005876', 'wikidata': 'https://www.wikidata.org/wiki/Q189814', 'display_name': 'Endocytosis', 'level': 3, 'score': 0.92101735}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7902492}, {'id': 'https://openalex.org/C207332259', 'wikidata': 'https://www.wikidata.org/wiki/Q769143', 'display_name': 'GTPase', 'level': 2, 'score': 0.7400058}, {'id': 'https://openalex.org/C79747257', 'wikidata': 'https://www.wikidata.org/wiki/Q189814', 'display_name': 'Endocytic cycle', 'level': 4, 'score': 0.6999086}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.66072243}, {'id': 'https://openalex.org/C38676607', 'wikidata': 'https://www.wikidata.org/wiki/Q6815140', 'display_name': 'Membrane ruffling', 'level': 4, 'score': 0.5394012}, {'id': 'https://openalex.org/C182704531', 'wikidata': 'https://www.wikidata.org/wiki/Q1364740', 'display_name': 'Knockout mouse', 'level': 3, 'score': 0.47471133}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.29465264}, {'id': 'https://openalex.org/C142669718', 'wikidata': 'https://www.wikidata.org/wiki/Q154626', 'display_name': 'Cytoskeleton', 'level': 3, 'score': 0.26340935}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.17623577}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.119589835}], 'mesh': [{'descriptor_ui': 'D034284', 'descriptor_name': 'Dynamin I', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D034285', 'descriptor_name': 'Dynamin II', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D034286', 'descriptor_name': 'Dynamin III', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D013569', 'descriptor_name': 'Synapses', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034284', 'descriptor_name': 'Dynamin I', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D034284', 'descriptor_name': 'Dynamin I', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034285', 'descriptor_name': 'Dynamin II', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D034285', 'descriptor_name': 'Dynamin II', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034286', 'descriptor_name': 'Dynamin III', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D034286', 'descriptor_name': 'Dynamin III', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004705', 'descriptor_name': 'Endocytosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004705', 'descriptor_name': 'Endocytosis', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D055786', 'descriptor_name': 'Gene Knockout Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006835', 'descriptor_name': 'Hydrazones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006835', 'descriptor_name': 'Hydrazones', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009284', 'descriptor_name': 'Naphthols', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009284', 'descriptor_name': 'Naphthols', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D013569', 'descriptor_name': 'Synapses', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1242/jcs.138578', 'pdf_url': 'https://jcs.biologists.org/content/joces/126/22/5305.full.pdf', 'source': {'id': 'https://openalex.org/S5677253', 'display_name': 'Journal of Cell Science', 'issn_l': '0021-9533', 'issn': ['0021-9533', '1477-9137'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3828596', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828596', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24046449', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1242/jcs.138578', 'pdf_url': 'https://jcs.biologists.org/content/joces/126/22/5305.full.pdf', 'source': {'id': 'https://openalex.org/S5677253', 'display_name': 'Journal of Cell Science', 'issn_l': '0021-9533', 'issn': ['0021-9533', '1477-9137'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 67, 'referenced_works': ['https://openalex.org/W1491787713', 'https://openalex.org/W1502026371', 'https://openalex.org/W1526128150', 'https://openalex.org/W1536382528', 'https://openalex.org/W1538926863', 'https://openalex.org/W1574831557', 'https://openalex.org/W1585616862', 'https://openalex.org/W1970669095', 'https://openalex.org/W1970851569', 'https://openalex.org/W1973096186', 'https://openalex.org/W1974137853', 'https://openalex.org/W1974195547', 'https://openalex.org/W1981431290', 'https://openalex.org/W1986972844', 'https://openalex.org/W1989894857', 'https://openalex.org/W1991893658', 'https://openalex.org/W1991972640', 'https://openalex.org/W2000531537', 'https://openalex.org/W2000678571', 'https://openalex.org/W2004351850', 'https://openalex.org/W2007669066', 'https://openalex.org/W2009018171', 'https://openalex.org/W2015879663', 'https://openalex.org/W2016484067', 'https://openalex.org/W2020372995', 'https://openalex.org/W2022634792', 'https://openalex.org/W2026049773', 'https://openalex.org/W2029873308', 'https://openalex.org/W2033264288', 'https://openalex.org/W2033978875', 'https://openalex.org/W2036484541', 'https://openalex.org/W2038622174', 'https://openalex.org/W2039313004', 'https://openalex.org/W2042527044', 'https://openalex.org/W2051410189', 'https://openalex.org/W2055473408', 'https://openalex.org/W2055555352', 'https://openalex.org/W2056787790', 'https://openalex.org/W2058568944', 'https://openalex.org/W2063414626', 'https://openalex.org/W2065828105', 'https://openalex.org/W2068177704', 'https://openalex.org/W2070914973', 'https://openalex.org/W2079900215', 'https://openalex.org/W2081222984', 'https://openalex.org/W2084489003', 'https://openalex.org/W2094123735', 'https://openalex.org/W2096476993', 'https://openalex.org/W2096829751', 'https://openalex.org/W2105364466', 'https://openalex.org/W2106675234', 'https://openalex.org/W2107651598', 'https://openalex.org/W2107775821', 'https://openalex.org/W2107801352', 'https://openalex.org/W2112032807', 'https://openalex.org/W2122132740', 'https://openalex.org/W2124818274', 'https://openalex.org/W2145525047', 'https://openalex.org/W2151249393', 'https://openalex.org/W2151888693', 'https://openalex.org/W2157963288', 'https://openalex.org/W2158621547', 'https://openalex.org/W2167118899', 'https://openalex.org/W2167806590', 'https://openalex.org/W2172095199', 'https://openalex.org/W2409486774', 'https://openalex.org/W2804806451'], 'related_works': ['https://openalex.org/W3175753174', 'https://openalex.org/W3132603526', 'https://openalex.org/W2761193853', 'https://openalex.org/W2149387052', 'https://openalex.org/W2139539366', 'https://openalex.org/W2064968758', 'https://openalex.org/W2051841888', 'https://openalex.org/W2013112818', 'https://openalex.org/W1570552209', 'https://openalex.org/W1505938433'], 'abstract_inverted_index': {'Dynamin,': [0], 'which': [1], 'is': [2, 9, 29], 'encoded': [3], 'by': [4, 131], 'three': [5, 136], 'genes': [6], 'in': [7, 13, 24, 66, 83, 116, 154], 'mammals,': [8], 'a': [10, 69], 'GTPase': [11], 'implicated': [12], 'endocytic': [14], 'membrane': [15, 126], 'fission.': [16], 'Dynamin': [17, 161], '1': [18, 53], 'and': [19, 50, 54, 97, 124, 146, 158, 175], '3': [20, 81, 98], 'are': [21], 'predominantly': [22], 'expressed': [23], 'brain,': [25], 'while': [26, 120], 'dynamin': [27, 43, 52, 80, 94, 143, 181], '2': [28, 55], 'ubiquitously': [30], 'expressed.': [31], 'With': [32], 'the': [33, 37, 40, 79, 132, 169, 176], 'goal': [34], 'of': [35, 39, 42, 68, 72, 78, 134, 172, 178], 'assessing': [36], 'impact': [38], 'lack': [41, 133], 'on': [44], 'cell': [45], 'physiology,': [46], 'we': [47, 90], 'previously': [48, 114], 'generated': [49], 'characterized': [51], 'double': [56], 'KO': [57, 100], '(DKO)': [58], 'fibroblasts.': [59, 102, 118], 'These': [60, 103], 'DKO': [61, 117], 'cells': [62, 85, 104, 157, 163], 'were': [63, 128], 'unexpectedly': [64], 'viable': [65], 'spite': [67], 'severe': [70], 'impairment': [71], 'clathrin-mediated': [73], 'endocytosis.': [74], 'As': [75], 'low-level': [76], 'expression': [77], 'gene': [82], 'these': [84, 150], 'could': [86], 'not': [87, 106, 129], 'be': [88, 165], 'excluded,': [89], 'have': [91], 'now': [92], 'engineered': [93], '1,': [95], '2,': [96], 'triple': [99], '(TKO)': [101], 'did': [105], 'reveal': [107], 'any': [108], 'additional': [109], 'defects': [110], 'beyond': [111], 'what': [112], 'was': [113], 'observed': [115], 'Surprisingly,': [119], 'fluid': [121], 'phase': [122], 'endocytosis': [123], 'peripheral': [125], 'ruffling': [127], 'impaired': [130], 'all': [135], 'dynamins,': [137], 'two': [138, 151], 'structurally': [139], 'similar,': [140], 'widely': [141], 'used': [142], 'inhibitors,': [144], 'dynasore': [145], 'Dyngo-4a,': [147], 'robustly': [148], 'inhibited': [149], 'processes': [152, 174], 'both': [153], 'wild': [155], 'type': [156], 'TKO': [159, 162], 'cells.': [160], 'will': [164], 'useful': [166], 'tools': [167], 'for': [168], 'further': [170], 'exploration': [171], 'dynamin-dependent': [173], 'development': [177], 'more': [179], 'specific': [180], 'inhibitors.': [182]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2030588833', 'counts_by_year': [{'year': 2024, 'cited_by_count': 17}, {'year': 2023, 'cited_by_count': 15}, {'year': 2022, 'cited_by_count': 22}, {'year': 2021, 'cited_by_count': 28}, {'year': 2020, 'cited_by_count': 18}, {'year': 2019, 'cited_by_count': 16}, {'year': 2018, 'cited_by_count': 28}, {'year': 2017, 'cited_by_count': 21}, {'year': 2016, 'cited_by_count': 16}, {'year': 2015, 'cited_by_count': 21}, {'year': 2014, 'cited_by_count': 27}], 'updated_date': '2024-09-13T09:41:48.074988', 'created_date': '2016-06-24'}