Title: Management of preterm premature rupture of the membranes then and now—are outcomes different?
Abstract: Objective: To analyze the success of current management strategies in patients with preterm premature rupture of the membrane (PPROM) by comparing maternal and neonatal outcomes past and present. Methods: Twenty-two cases of PPROM between 24 and 33 weeks of estimated gestational age (EGA) from 1989 to 1991 were analyzed and compared with the same number of patients from 1997 to 1999. Both groups were matched for race, parity, age, EGA at the time of PPROM, and EGA at delivery. Neonatal care also was matched between the two groups to include use of surfactant, antibiotics, and ventilator support. Group 1 received no antibiotics and steroids and received tocolysis only if in preterm labor. Maternal and neonatal outcomes were analyzed using χ2 and one-way analysis of variance. Results: A significant difference was seen in the mean latent period, with group 2 being 12.2 days versus 7.6 days in group 1 (P <0.05). A significant difference did exist in average ventilator days, with group 2 being 3.6 days versus 12 days in group 1. Conclusions: Current management of PPROM demonstrates longer latent periods attributed to the use of prophylactic antibiotics. Antenatal steroids and antibiotics were associated with fewer ventilator days and did not increase infectious morbidity for mothers or babies.
Publication Year: 2000
Publication Date: 2000-06-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 1
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